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1JMH
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BU of 1jmh by Molmil
CONTRIBUTIONS OF ORIENTATION AND HYDROGEN BONDING TO CATALYSIS IN ASN-229 MUTANTS OF THYMIDYLATE SYNTHASE
Descriptor: 2'-DEOXYURIDINE 5'-MONOPHOSPHATE, THYMIDYLATE SYNTHASE
Authors:Finer-Moore, J, Stroud, R.M.
Deposit date:1997-09-13
Release date:1998-01-28
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Contributions of orientation and hydrogen bonding to catalysis in Asn229 mutants of thymidylate synthase.
J.Mol.Biol., 276, 1998
1JMI
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BU of 1jmi by Molmil
CONTRIBUTIONS OF ORIENTATION AND HYDROGEN BONDING TO CATALYSIS IN ASN-229 MUTANTS OF THYMIDYLATE SYNTHASE
Descriptor: 2'-DEOXYURIDINE 5'-MONOPHOSPHATE, THYMIDYLATE SYNTHASE
Authors:Finer-Moore, J, Stroud, R.M.
Deposit date:1997-09-13
Release date:1998-01-28
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Contributions of orientation and hydrogen bonding to catalysis in Asn229 mutants of thymidylate synthase.
J.Mol.Biol., 276, 1998
1K6X
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BU of 1k6x by Molmil
Crystal structure of Nmra, a negative transcriptional regulator in complex with NAD at 1.5 A resolution (Trigonal form)
Descriptor: CHLORIDE ION, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, NmrA
Authors:Stammers, D.K, Ren, J, Leslie, K, Nichols, C.E, Lamb, H.K, Cocklin, S, Dodds, A, Hawkins, A.R.
Deposit date:2001-10-17
Release date:2002-02-20
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:The structure of the negative transcriptional regulator NmrA reveals a structural superfamily which includes the short-chain dehydrogenase/reductases.
EMBO J., 20, 2002
3NB5
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BU of 3nb5 by Molmil
Human carbonic anhydrase II in complex with 2-(3-chloro-4-hydroxyphenyl)-N-(4-sulfamoylphenethyl)acetamide
Descriptor: 2-(3-chloro-4-hydroxyphenyl)-N-[2-(4-sulfamoylphenyl)ethyl]acetamide, Carbonic anhydrase 2, GLYCEROL, ...
Authors:Hofmann, A, Osman, A, Davis, R.A.
Deposit date:2010-06-02
Release date:2011-04-20
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Natural Product-Based Phenols as Novel Probes for Mycobacterial and Fungal Carbonic Anhydrases
J.Med.Chem., 54, 2011
3NHM
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BU of 3nhm by Molmil
Crystal structure of a response regulator from Myxococcus xanthus
Descriptor: Response regulator
Authors:Palani, K, Burley, S.K, Swaminathan, S, New York SGX Research Center for Structural Genomics (NYSGXRC)
Deposit date:2010-06-14
Release date:2010-07-21
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.19 Å)
Cite:Crystal structure of a response regulator from Myxococcus xanthus
To be Published
3N0E
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BU of 3n0e by Molmil
Crystal structure of WDR5 mutant (W330Y)
Descriptor: WD repeat-containing protein 5
Authors:Wu, Y.-D, Wu, X.-H, Gao, Y, Chen, R.-C.
Deposit date:2010-05-13
Release date:2010-10-20
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:The Effect of Asp-His-Ser/Thr-Trp Tetrad on the Thermostability of WD40-Repeat Proteins
Biochemistry, 49, 2010
1K63
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Complex of hydrolytic haloalkane dehalogenase linb from sphingomonas paucimobilis with UT26 2-BROMO-2-PROPENE-1-OL at 1.8A resolution
Descriptor: 1,3,4,6-tetrachloro-1,4-cyclohexadiene hydrolase, 2-BROMO-2-PROPENE-1-OL, BROMIDE ION, ...
Authors:Streltsov, V.A, Damborsky, J, Wilce, M.C.J.
Deposit date:2001-10-15
Release date:2003-08-26
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Haloalkane dehalogenase LinB from Sphingomonas paucimobilis UT26: X-ray crystallographic studies of dehalogenation of brominated substrates
Biochemistry, 42, 2003
1K6J
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Crystal structure of Nmra, a negative transcriptional regulator (Monoclinic form)
Descriptor: CHLORIDE ION, NmrA
Authors:Stammers, D.K, Ren, J, Leslie, K, Nichols, C.E, Lamb, H.K, Cocklin, S, Dodds, A, Hawkins, A.R.
Deposit date:2001-10-16
Release date:2002-02-20
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:The structure of the negative transcriptional regulator NmrA reveals a structural superfamily which includes the short-chain dehydrogenase/reductases.
EMBO J., 20, 2001
1K73
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Co-crystal Structure of Anisomycin Bound to the 50S Ribosomal Subunit
Descriptor: 23S RRNA, 5S RRNA, ANISOMYCIN, ...
Authors:Hansen, J, Ban, N, Nissen, P, Moore, P.B, Steitz, T.A.
Deposit date:2001-10-18
Release date:2003-07-22
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (3.01 Å)
Cite:Structures of Five Antibiotics Bound at the Peptidyl Transferase Center of the Large Ribosomal Subunit
J.Mol.Biol., 330, 2003
1K6E
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BU of 1k6e by Molmil
COMPLEX OF HYDROLYTIC HALOALKANE DEHALOGENASE LINB FROM SPHINGOMONAS PAUCIMOBILIS UT26 WITH 1,2-PROPANEDIOL (PRODUCT OF DEHALOGENATION OF 1,2-DIBROMOPROPANE) AT 1.85A
Descriptor: 1-BROMOPROPANE-2-OL, BROMIDE ION, CHLORIDE ION, ...
Authors:Streltsov, V.A, Prokop, Z, Damborsky, J, Nagata, Y, Oakley, A, Wilce, M.C.J.
Deposit date:2001-10-16
Release date:2003-08-19
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Haloalkane dehalogenase LinB from Sphingomonas paucimobilis UT26: X-ray crystallographic studies of dehalogenation of brominated substrates.
Biochemistry, 42, 2003
1K6I
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BU of 1k6i by Molmil
Crystal structure of Nmra, a negative transcriptional regulator (Trigonal form)
Descriptor: CHLORIDE ION, NmrA
Authors:Stammers, D.K, Ren, J, Leslie, K, Nichols, C.E, Lamb, H.K, Cocklin, S, Dodds, A, Hawkins, A.R.
Deposit date:2001-10-16
Release date:2001-12-05
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:The structure of the negative transcriptional regulator NmrA reveals a structural superfamily which includes the short-chain dehydrogenase/reductases.
EMBO J., 20, 2001
1K8W
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BU of 1k8w by Molmil
Crystal structure of the E. coli pseudouridine synthase TruB bound to a T stem-loop RNA
Descriptor: 5'-R(*GP*GP*CP*AP*AP*CP*GP*GP*UP*(FHU)P*CP*GP*AP*UP*CP*CP*CP*GP*UP*UP*GP*C)-3', SULFATE ION, tRNA Pseudouridine Synthase B
Authors:Hoang, C, Ferre-D'Amare, A.R.
Deposit date:2001-10-25
Release date:2001-12-31
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Cocrystal structure of a tRNA Psi55 pseudouridine synthase: nucleotide flipping by an RNA-modifying enzyme.
Cell(Cambridge,Mass.), 107, 2001
8CH7
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BU of 8ch7 by Molmil
RDC-refined Interleukin-4 (wild type) pH 5.6
Descriptor: Interleukin-4
Authors:Vaz, D.C, Rodrigues, J.R, Loureiro-Ferreira, N, Mueller, T, Sebald, W, Redfield, C, Brito, R.M.M.
Deposit date:2023-02-07
Release date:2023-10-18
Last modified:2024-01-17
Method:SOLUTION NMR
Cite:Lessons on protein structure from interleukin-4: All disulfides are not created equal.
Proteins, 92, 2024
8CGF
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BU of 8cgf by Molmil
Interleukin-4 (wild type) pH 2.4
Descriptor: Interleukin-4
Authors:Vaz, D.C, Rodrigues, J.R, Loureiro-Ferreira, N, Mueller, T, Sebald, W, Redfield, C, Brito, R.M.M.
Deposit date:2023-02-04
Release date:2023-10-18
Last modified:2024-01-17
Method:SOLUTION NMR
Cite:Lessons on protein structure from interleukin-4: All disulfides are not created equal.
Proteins, 92, 2024
1KUQ
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BU of 1kuq by Molmil
CRYSTAL STRUCTURE OF T3C MUTANT S15 RIBOSOMAL PROTEIN IN COMPLEX WITH 16S RRNA
Descriptor: 16S RIBOSOMAL RNA FRAGMENT, 30S RIBOSOMAL PROTEIN S15, SULFATE ION
Authors:Nikulin, A.D, Tishchenko, S, Revtovich, S, Ehresmann, B, Ehresmann, C, Dumas, P, Garber, M, Nikonov, S, Nevskaya, N.
Deposit date:2002-01-22
Release date:2003-06-24
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2.84 Å)
Cite:Role of N-terminal helix in interaction of ribosomal protein S15 with 16S rRNA.
Biochemistry Mosc., 69, 2004
1K8A
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BU of 1k8a by Molmil
Co-crystal structure of Carbomycin A bound to the 50S ribosomal subunit of Haloarcula marismortui
Descriptor: 23S RRNA, 5S RRNA, CADMIUM ION, ...
Authors:Hansen, J.L, Ippolito, J.A, Ban, N, Nissen, P, Moore, P.B, Steitz, T.
Deposit date:2001-10-23
Release date:2002-07-19
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (3 Å)
Cite:The structures of four macrolide antibiotics bound to the large ribosomal subunit.
Mol.Cell, 10, 2002
1KD3
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BU of 1kd3 by Molmil
The Crystal Structure of r(GGUCACAGCCC)2, Thallium form
Descriptor: 5'-R(*GP*GP*UP*CP*AP*CP*AP*GP*CP*CP*C)-3', THALLIUM (I) ION
Authors:Kacer, V, Scaringe, S.A, Scarsdale, J.N, Rife, J.P.
Deposit date:2001-11-12
Release date:2003-03-04
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal structures of r(GGUCACAGCCC)2.
Acta Crystallogr.,Sect.D, 59, 2003
1KD4
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BU of 1kd4 by Molmil
The Crystal Structure of r(GGUCACAGCCC)2, Barium form
Descriptor: 5'-R(*GP*GP*UP*CP*AP*CP*AP*GP*CP*CP*C)-3', BARIUM ION
Authors:Kacer, V, Scaringe, S.A, Scarsdale, J.N, Rife, J.P.
Deposit date:2001-11-12
Release date:2003-03-04
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Crystal structures of r(GGUCACAGCCC)2.
Acta Crystallogr.,Sect.D, 59, 2003
3N89
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BU of 3n89 by Molmil
KH domains
Descriptor: Defective in germ line development protein 3, isoform a
Authors:Nakel, K, Hartung, S.A, Bonneau, F, Eckmann, C.R, Conti, E.
Deposit date:2010-05-28
Release date:2010-09-22
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.789 Å)
Cite:Four KH domains of the C. elegans Bicaudal-C ortholog GLD-3 form a globular structural platform.
Rna, 16, 2010
1KOG
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BU of 1kog by Molmil
Crystal structure of E. coli threonyl-tRNA synthetase interacting with the essential domain of its mRNA operator
Descriptor: 5'-O-(N-(L-THREONYL)-SULFAMOYL)ADENOSINE, Threonyl-tRNA synthetase, Threonyl-tRNA synthetase mRNA, ...
Authors:Torres-Larrios, A, Dock-Bregeon, A.C, Romby, P, Rees, B, Sankaranarayanan, R, Caillet, J, Springer, M, Ehresmann, C, Ehresmann, B, Moras, D.
Deposit date:2001-12-20
Release date:2002-04-26
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Structural basis of translational control by Escherichia coli threonyl tRNA synthetase.
Nat.Struct.Biol., 9, 2002
9BIV
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BU of 9biv by Molmil
Crystal Structure of Ubc13 with a New Active Site Loop Conformation
Descriptor: Ubiquitin-conjugating enzyme E2 N, Ubiquitin-conjugating enzyme E2 variant 2
Authors:Farraj, R.A, Edwards, R.A, Glover, J.N.M.
Deposit date:2024-04-24
Release date:2024-05-08
Method:X-RAY DIFFRACTION (1.68 Å)
Cite:Crystal Structure of Ubc13 with a New Active Site Loop Conformation
To Be Published
1KQS
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BU of 1kqs by Molmil
The Haloarcula marismortui 50S Complexed with a Pretranslocational Intermediate in Protein Synthesis
Descriptor: 23S RRNA, 5S RRNA, 6-AMINOHEXANOIC ACID, ...
Authors:Schmeing, T.M, Seila, A.C, Hansen, J.L, Freeborn, B, Soukup, J.K, Scaringe, S.A, Strobel, S.A, Moore, P.B, Steitz, T.A.
Deposit date:2002-01-07
Release date:2002-02-22
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:A pre-translocational intermediate in protein synthesis observed in crystals of enzymatically active 50S subunits.
Nat.Struct.Biol., 9, 2002
1KNC
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Structure of AhpD from Mycobacterium tuberculosis, a novel enzyme with thioredoxin-like activity.
Descriptor: AhpD protein, SULFATE ION
Authors:Bryk, R, Lima, C.D, Erdjument-Bromage, H, Tempst, P, Nathan, C.
Deposit date:2001-12-18
Release date:2002-01-23
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2 Å)
Cite:Metabolic enzymes of mycobacteria linked to antioxidant defense by a thioredoxin-like protein.
Science, 295, 2002
8T9D
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BU of 8t9d by Molmil
CryoEM structure of TR-TRAP
Descriptor: Mediator of RNA polymerase II transcription subunit 1, Mediator of RNA polymerase II transcription subunit 10, Mediator of RNA polymerase II transcription subunit 11, ...
Authors:Zhao, H, Asturias, F.
Deposit date:2023-06-23
Release date:2024-07-03
Last modified:2024-08-07
Method:ELECTRON MICROSCOPY (4.66 Å)
Cite:An IDR-dependent mechanism for nuclear receptor control of Mediator interaction with RNA polymerase II.
Mol.Cell, 84, 2024
2VUK
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Structure of the p53 core domain mutant Y220C bound to the stabilizing small-molecule drug PhiKan083
Descriptor: 1-(9-ethyl-9H-carbazol-3-yl)-N-methylmethanamine, CELLULAR TUMOR ANTIGEN P53, ZINC ION
Authors:Joerger, A.C, Boeckler, F.M, Fersht, A.R.
Deposit date:2008-05-26
Release date:2008-07-22
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Targeted Rescue of a Destabilized Mutant of P53 by an in Silico Screened Drug.
Proc.Natl.Acad.Sci.USA, 105, 2008

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