1JMI
CONTRIBUTIONS OF ORIENTATION AND HYDROGEN BONDING TO CATALYSIS IN ASN-229 MUTANTS OF THYMIDYLATE SYNTHASE
Summary for 1JMI
| Entry DOI | 10.2210/pdb1jmi/pdb |
| Descriptor | THYMIDYLATE SYNTHASE, 2'-DEOXYURIDINE 5'-MONOPHOSPHATE (3 entities in total) |
| Functional Keywords | transferase, methyltransferase |
| Biological source | Lactobacillus casei |
| Cellular location | Cytoplasm: P00469 |
| Total number of polymer chains | 1 |
| Total formula weight | 36911.61 |
| Authors | Finer-Moore, J.,Stroud, R.M. (deposition date: 1997-09-13, release date: 1998-01-28, Last modification date: 2024-02-07) |
| Primary citation | Finer-Moore, J.S.,Liu, L.,Birdsall, D.L.,Brem, R.,Apfeld, J.,Santi, D.V.,Stroud, R.M. Contributions of orientation and hydrogen bonding to catalysis in Asn229 mutants of thymidylate synthase. J.Mol.Biol., 276:113-129, 1998 Cited by PubMed: 9514716DOI: 10.1006/jmbi.1997.1495 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.5 Å) |
Structure validation
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