2ML3
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6ADD
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![BU of 6add by Molmil](/molmil-images/mine/6add) | The crystal structure of Rv2747 from Mycobacterium tuberculosis in complex with CoA and NLQ | Descriptor: | Amino-acid acetyltransferase, COENZYME A, N~2~-ACETYL-L-GLUTAMINE | Authors: | Das, U, Singh, E, Pal, R.K, Tiruttani Subhramanyam, U.K, Gourinath, S, Srinivasan, A. | Deposit date: | 2018-07-31 | Release date: | 2018-12-26 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.301 Å) | Cite: | Structural insights into the substrate binding mechanism of novel ArgA from Mycobacterium tuberculosis Int. J. Biol. Macromol., 125, 2019
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2BNA
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2HJS
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![BU of 2hjs by Molmil](/molmil-images/mine/2hjs) | The structure of a probable aspartate-semialdehyde dehydrogenase from Pseudomonas aeruginosa | Descriptor: | 1,4-DIETHYLENE DIOXIDE, USG-1 protein homolog | Authors: | Cuff, M.E, Evdokimova, E, Kudritska, M, Edwards, A, Savchenko, A, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2006-06-30 | Release date: | 2006-08-29 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | The structure of a probable aspartate-semialdehyde dehydrogenase from Pseudomonas aeruginosa To be published
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1P6H
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![BU of 1p6h by Molmil](/molmil-images/mine/1p6h) | Rat neuronal NOS heme domain with L-N(omega)-nitroarginine-2,4-L-diaminobutyric amide bound | Descriptor: | 5,6,7,8-TETRAHYDROBIOPTERIN, ACETATE ION, L-N(OMEGA)-NITROARGININE-2,4-L-DIAMINOBUTYRIC AMIDE, ... | Authors: | Flinspach, M.L, Li, H, Jamal, J, Yang, W, Huang, H, Hah, J.-M, Gomez-Vidal, J.A, Litzinger, E.A, Silverman, R.B, Poulos, T.L. | Deposit date: | 2003-04-29 | Release date: | 2004-01-13 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.98 Å) | Cite: | Structural basis for dipeptide amide isoform-selective inhibition of neuronal nitric oxide synthase. Nat.Struct.Mol.Biol., 11, 2004
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3E4D
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![BU of 3e4d by Molmil](/molmil-images/mine/3e4d) | Structural and Kinetic Study of an S-Formylglutathione Hydrolase from Agrobacterium tumefaciens | Descriptor: | CHLORIDE ION, Esterase D, MAGNESIUM ION | Authors: | Van Straaten, K.E, Gonzalez, C.F, Valladares, R.B, Xu, X, Savchenko, A.V, Sanders, D.A.R. | Deposit date: | 2008-08-11 | Release date: | 2009-08-18 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.01 Å) | Cite: | The structure of a putative S-formylglutathione hydrolase from Agrobacterium tumefaciens Protein Sci., 18, 2009
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7KHW
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5KYM
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![BU of 5kym by Molmil](/molmil-images/mine/5kym) | Crystal Structure of the 1-acyl-sn-glycerophosphate (LPA) acyltransferase, PlsC, from Thermotoga maritima | Descriptor: | 1-HEPTADECANOYL-2-TRIDECANOYL-3-GLYCEROL-PHOSPHONYL CHOLINE, 1-acyl-sn-glycerol-3-phosphate acyltransferase, DODECYL-BETA-D-MALTOSIDE, ... | Authors: | Robertson, R.M, Yao, J, Gajewski, S, Kumar, G, Martin, E.W, Rock, C.O, White, S.W. | Deposit date: | 2016-07-21 | Release date: | 2017-07-26 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | A two-helix motif positions the lysophosphatidic acid acyltransferase active site for catalysis within the membrane bilayer. Nat. Struct. Mol. Biol., 24, 2017
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3EP3
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![BU of 3ep3 by Molmil](/molmil-images/mine/3ep3) | Human AdoMetDC D174N mutant with no putrescine bound | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, PYRUVIC ACID, S-adenosylmethionine decarboxylase alpha chain, ... | Authors: | Bale, S, Lopez, M.M, Makhatadze, G.I, Fang, Q, Pegg, A.E, Ealick, S.E. | Deposit date: | 2008-09-29 | Release date: | 2008-12-23 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (1.84 Å) | Cite: | Structural Basis for Putrescine Activation of Human S-Adenosylmethionine Decarboxylase. Biochemistry, 47, 2008
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3E7G
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![BU of 3e7g by Molmil](/molmil-images/mine/3e7g) | Structure of human INOSOX with inhibitor AR-C95791 | Descriptor: | 5,6,7,8-TETRAHYDROBIOPTERIN, ETHYL 4-[(4-METHYLPYRIDIN-2-YL)AMINO]PIPERIDINE-1-CARBOXYLATE, Nitric oxide synthase, ... | Authors: | Garcin, E.D, Arvai, A.S, Rosenfeld, R.J, Kroeger, M.D, Crane, B.R, Andersson, G, Andrews, G, Hamley, P.J, Mallinder, P.R, Nicholls, D.J, St-Gallay, S.A, Tinker, A.C, Gensmantel, N.P, Mete, A, Cheshire, D.R, Connolly, S, Stueh, D.J, Aberg, A, Wallace, A.V, Tainer, J.A, Getzoff, E.D. | Deposit date: | 2008-08-18 | Release date: | 2008-10-07 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Anchored plasticity opens doors for selective inhibitor design in nitric oxide synthase. Nat.Chem.Biol., 4, 2008
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2MHX
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![BU of 2mhx by Molmil](/molmil-images/mine/2mhx) | Structure of Exocyclic R,R N6,N6-(2,3-Dihydroxy-1,4-butadiyl)-2'-Deoxyadenosine Adduct Induced by 1,2,3,4-Diepoxybutane in DNA | Descriptor: | 5'-D(*CP*GP*GP*AP*CP*(RBD)P*AP*GP*AP*AP*G)-3'), 5'-D(*CP*TP*TP*CP*TP*TP*GP*TP*CP*CP*G)-3') | Authors: | Kowal, E.A, Seneviratne, U, Wickramaratne, S, Doherty, K.E, Cao, X, Tretyakova, N, Stone, M.P. | Deposit date: | 2013-12-05 | Release date: | 2014-05-28 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | Structures of Exocyclic R,R- and S,S-N(6),N(6)-(2,3-Dihydroxybutan-1,4-diyl)-2'-Deoxyadenosine Adducts Induced by 1,2,3,4-Diepoxybutane. Chem.Res.Toxicol., 27, 2014
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3O6Z
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![BU of 3o6z by Molmil](/molmil-images/mine/3o6z) | Structure of the D152A E.coli GDP-mannose hydrolase (yffh) in complex with Mg++ | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ... | Authors: | Amzel, L.M, Gabelli, S.B, Boto, A.N. | Deposit date: | 2010-07-29 | Release date: | 2011-05-11 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | Structural studies of the Nudix GDP-mannose hydrolase from E. coli reveals a new motif for mannose recognition. Proteins, 79, 2011
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7KWQ
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![BU of 7kwq by Molmil](/molmil-images/mine/7kwq) | Spermidine N-acetyltransferase SpeG R149-K152 chimera from Vibrio cholerae and hSSAT | Descriptor: | Spermidine N(1)-acetyltransferase | Authors: | Le, V.T.B, Tsimbalyuk, S, Lim, E.Q, Solis, A, Gawat, D, Boeck, P, Renolo, R, Forwood, J.K, Kuhn, M.L. | Deposit date: | 2020-12-01 | Release date: | 2020-12-16 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | The Vibrio cholerae SpeG Spermidine/Spermine N -Acetyltransferase Allosteric Loop and beta 6-beta 7 Structural Elements Are Critical for Kinetic Activity. Front Mol Biosci, 8, 2021
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1P7J
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![BU of 1p7j by Molmil](/molmil-images/mine/1p7j) | Crystal structure of engrailed homeodomain mutant K52E | Descriptor: | 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, Segmentation polarity homeobox protein engrailed | Authors: | Stollar, E.J, Mayor, U, Lovell, S.C, Federici, L, Freund, S.M, Fersht, A.R, Luisi, B.F. | Deposit date: | 2003-05-02 | Release date: | 2003-10-14 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Crystal Structures of Engrailed Homeodomain Mutants: IMPLICATIONS FOR STABILITY AND DYNAMICS J.Biol.Chem., 278, 2003
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5YAE
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![BU of 5yae by Molmil](/molmil-images/mine/5yae) | Ferulic acid esterase from Streptomyces cinnamoneus at 2.4 A resolution | Descriptor: | ACETATE ION, Esterase, SULFATE ION | Authors: | Tamura, H, Uraji, M, Mizohata, E, Ogawa, K, Inoue, T, Hatanaka, T. | Deposit date: | 2017-08-31 | Release date: | 2017-12-06 | Last modified: | 2018-01-31 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Loop of Streptomyces Feruloyl Esterase Plays an Important Role in the Enzyme's Catalyzing the Release of Ferulic Acid from Biomass. Appl. Environ. Microbiol., 84, 2018
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4HMR
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![BU of 4hmr by Molmil](/molmil-images/mine/4hmr) | Crystal structure of mutant rabbit PRP 121-230 (S170N/S174N) | Descriptor: | CHLORIDE ION, GLYCEROL, Major prion protein, ... | Authors: | Sweeting, B, Chakrabartty, A, Pai, E.F. | Deposit date: | 2012-10-18 | Release date: | 2013-05-15 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | N-Terminal Helix-Cap in alpha-Helix 2 Modulates beta-State Misfolding in Rabbit and Hamster Prion Proteins. Plos One, 8, 2013
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5IHR
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![BU of 5ihr by Molmil](/molmil-images/mine/5ihr) | STRUCTURE OF E298Q-BETA-GALACTOSIDASE FROM ASPERGILLUS NIGER IN COMPLEX WITH ALLOLACTOSE | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, DIMETHYL SULFOXIDE, ... | Authors: | Rico-Diaz, A, Ramirez-Escudero, M, Vizoso Vazquez, A, Cerdan, M.E, Becerra, M, Sanz-Aparicio, J. | Deposit date: | 2016-02-29 | Release date: | 2017-04-19 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Structural features of Aspergillus niger beta-galactosidase define its activity against glycoside linkages. FEBS J., 284, 2017
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1RZH
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![BU of 1rzh by Molmil](/molmil-images/mine/1rzh) | PHOTOSYNTHETIC REACTION CENTER DOUBLE MUTANT FROM RHODOBACTER SPHAEROIDES WITH ASP L213 REPLACED WITH ASN AND ARG M233 REPLACED WITH CYS IN THE CHARGE-NEUTRAL DQAQB STATE (TRIGONAL FORM) | Descriptor: | BACTERIOCHLOROPHYLL A, BACTERIOPHEOPHYTIN A, CARDIOLIPIN, ... | Authors: | Xu, Q, Axelrod, H.L, Abresch, E.C, Paddock, M.L, Okamura, M.Y, Feher, G. | Deposit date: | 2003-12-24 | Release date: | 2004-04-13 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | X-Ray Structure Determination of Three Mutants of the Bacterial Photosynthetic Reaction Centers from Rb. sphaeroides; Altered Proton Transfer Pathways. STRUCTURE, 12, 2004
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1F1O
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![BU of 1f1o by Molmil](/molmil-images/mine/1f1o) | STRUCTURAL STUDIES OF ADENYLOSUCCINATE LYASES | Descriptor: | ADENYLOSUCCINATE LYASE | Authors: | Toth, E.A, Yeates, T. | Deposit date: | 2000-05-19 | Release date: | 2001-01-10 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (3.25 Å) | Cite: | The crystal structure of adenylosuccinate lyase from Pyrobaculum aerophilum reveals an intracellular protein with three disulfide bonds. J.Mol.Biol., 301, 2000
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3ILL
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![BU of 3ill by Molmil](/molmil-images/mine/3ill) | Crystal structure of E. coli HPPK(D97A) | Descriptor: | 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase, CHLORIDE ION | Authors: | Blaszczyk, J, Li, Y, Yan, H, Ji, X. | Deposit date: | 2009-08-07 | Release date: | 2010-08-11 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.73 Å) | Cite: | Structural and functional roles of residues D95 and D97 in E. coli HPPK To be Published
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7KX2
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![BU of 7kx2 by Molmil](/molmil-images/mine/7kx2) | Spermidine N-acetyltransferase SpeG F149A mutant from Vibrio cholerae | Descriptor: | Spermidine N(1)-acetyltransferase | Authors: | Le, V.T.B, Tsimbalyuk, S, Lim, E.Q, Solis, A, Gawat, D, Boeck, P, Renolo, R, Forwood, J.K, Kuhn, M.L. | Deposit date: | 2020-12-03 | Release date: | 2020-12-16 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | The Vibrio cholerae SpeG Spermidine/Spermine N -Acetyltransferase Allosteric Loop and beta 6-beta 7 Structural Elements Are Critical for Kinetic Activity. Front Mol Biosci, 8, 2021
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3FAL
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![BU of 3fal by Molmil](/molmil-images/mine/3fal) | humanRXR alpha & mouse LXR alpha complexed with Retenoic acid and GSK2186 | Descriptor: | 2-{4-[butyl(3-chloro-4,5-dimethoxybenzyl)amino]phenyl}-1,1,1,3,3,3-hexafluoropropan-2-ol, Oxysterols receptor LXR-alpha, RETINOIC ACID, ... | Authors: | Chao, E.Y, Caravella, J.A, Watson, M.A, Campobasso, N, Ghisletti, S, Billin, A.N, Galardi, C, Willson, T.M, Zuercher, W.J, Collins, J.L. | Deposit date: | 2008-11-17 | Release date: | 2009-04-14 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.36 Å) | Cite: | Structure-guided design of N-phenyl tertiary amines as transrepression-selective liver X receptor modulators with anti-inflammatory activity. J.Med.Chem., 51, 2008
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5KVA
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![BU of 5kva by Molmil](/molmil-images/mine/5kva) | Crystal Structure of sorghum caffeoyl-CoA O-methyltransferase (CCoAOMT) | Descriptor: | CALCIUM ION, S-ADENOSYLMETHIONINE, caffeoyl-CoA O-methyltransferase | Authors: | Walker, A.M, Sattler, S.A, Regner, M, Jones, J.P, Ralph, J, Vermerris, W, Sattler, S.E, Kang, C. | Deposit date: | 2016-07-14 | Release date: | 2016-08-10 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (1.827 Å) | Cite: | The Structure and Catalytic Mechanism of Sorghum bicolor Caffeoyl-CoA O-Methyltransferase. Plant Physiol., 172, 2016
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1MU2
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![BU of 1mu2 by Molmil](/molmil-images/mine/1mu2) | CRYSTAL STRUCTURE OF HIV-2 REVERSE TRANSCRIPTASE | Descriptor: | GLYCEROL, HIV-2 RT, SULFATE ION | Authors: | Ren, J, Bird, L.E, Chamberlain, P.P, Stewart-Jones, G.B, Stuart, D.I, Stammers, D.K. | Deposit date: | 2002-09-23 | Release date: | 2002-10-30 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.35 Å) | Cite: | Structure of HIV-2 reverse transcriptase at 2.35-A resolution and the mechanism of resistance to non-nucleoside inhibitors Proc.Natl.Acad.Sci.USA, 99, 2002
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1WS1
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![BU of 1ws1 by Molmil](/molmil-images/mine/1ws1) | |