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3NGO
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BU of 3ngo by Molmil
Crystal structure of the human CNOT6L nuclease domain in complex with poly(A) DNA
Descriptor: 5'-D(*AP*AP*AP*A)-3', CCR4-NOT transcription complex subunit 6-like, MAGNESIUM ION
Authors:Wang, H, Morita, M, Yang, W, Bartlam, M, Yamamoto, T, Rao, Z.
Deposit date:2010-06-12
Release date:2010-07-28
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal structure of the human CNOT6L nuclease domain reveals strict poly(A) substrate specificity.
Embo J., 2010
3NGN
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BU of 3ngn by Molmil
Crystal structure of the human CNOT6L nuclease domain in complex with AMP
Descriptor: ADENOSINE MONOPHOSPHATE, CCR4-NOT transcription complex subunit 6-like
Authors:Wang, H, Morita, M, Yang, W, Bartlam, M, Yamamoto, T, Rao, Z.
Deposit date:2010-06-12
Release date:2010-07-28
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal structure of the human CNOT6L nuclease domain reveals strict poly(A) substrate specificity.
Embo J., 2010
4X1E
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BU of 4x1e by Molmil
Crystal structure of unliganded E. coli transcriptional regulator RutR, W167A mutant
Descriptor: HTH-type transcriptional regulator RutR
Authors:Nguyen Le Minh, P, de Cima, S, Bervoets, I, Maes, D, Rubio, V, Charlier, D.
Deposit date:2014-11-24
Release date:2015-01-21
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Ligand binding specificity of RutR, a member of the TetR family of transcription regulators in Escherichia coli.
Febs Open Bio, 5, 2015
2AY0
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BU of 2ay0 by Molmil
Structure of the Lys9Met mutant of the E. coli Proline Utilization A (PutA) DNA-binding domain.
Descriptor: Bifunctional putA protein, CHLORIDE ION
Authors:Larson, J.D, Schuermann, J.P, Zhou, Y, Jenkins, J.L, Becker, D.F, Tanner, J.J.
Deposit date:2005-09-06
Release date:2006-08-15
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal structures of the DNA-binding domain of Escherichia coli proline utilization A flavoprotein and analysis of the role of Lys9 in DNA recognition.
Protein Sci., 15, 2006
3QPS
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BU of 3qps by Molmil
Crystal structures of CmeR-bile acid complexes from Campylobacter jejuni
Descriptor: CHOLIC ACID, CmeR
Authors:Lei, H.T, Routh, M.D, Shen, Z, Su, C.C, Zhang, Q, Yu, E.W.
Deposit date:2011-02-14
Release date:2011-03-09
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.351 Å)
Cite:Crystal structures of CmeR-bile acid complexes from Campylobacter jejuni.
Protein Sci., 20, 2011
3QQA
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BU of 3qqa by Molmil
Crystal structures of CmeR-bile acid complexes from Campylobacter jejuni
Descriptor: CmeR, TAUROCHOLIC ACID
Authors:Lei, H.T, Routh, M.D, Shen, Z, Su, C.-C, Zhang, Q, Yu, E.W.
Deposit date:2011-02-15
Release date:2011-03-16
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal structures of CmeR-bile acid complexes from Campylobacter jejuni.
Protein Sci., 20, 2011
5IT8
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BU of 5it8 by Molmil
High-resolution structure of the Escherichia coli ribosome
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, 1,2-ETHANEDIOL, 1,4-DIAMINOBUTANE, ...
Authors:Cocozaki, A, Ferguson, A.
Deposit date:2016-03-16
Release date:2016-07-27
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (3.12 Å)
Cite:Resistance mutations generate divergent antibiotic susceptibility profiles against translation inhibitors.
Proc.Natl.Acad.Sci.USA, 113, 2016
3C9C
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BU of 3c9c by Molmil
Structural Basis of Histone H4 Recognition by p55
Descriptor: CADMIUM ION, Chromatin assembly factor 1 p55 subunit, Histone H4, ...
Authors:Song, J.J, Garlick, J.D, Kingston, R.E.
Deposit date:2008-02-15
Release date:2008-05-13
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Structural basis of histone H4 recognition by p55.
Genes Dev., 22, 2008
4YBB
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BU of 4ybb by Molmil
High-resolution structure of the Escherichia coli ribosome
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, 1,2-ETHANEDIOL, 1,4-DIAMINOBUTANE, ...
Authors:Noeske, J, Wasserman, M.R, Terry, D.S, Altman, R.B, Blanchard, S.C, Cate, J.H.D.
Deposit date:2015-02-18
Release date:2015-03-18
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:High-resolution structure of the Escherichia coli ribosome.
Nat.Struct.Mol.Biol., 22, 2015
1LJ9
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BU of 1lj9 by Molmil
The crystal structure of the transcriptional regulator SlyA
Descriptor: transcriptional regulator SlyA
Authors:Wu, R.Y, Zhang, R.G, Gornicki, P, Joachimiak, A, Midwest Center for Structural Genomics (MCSG)
Deposit date:2002-04-19
Release date:2003-01-21
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Crystal structure of Enterococcus faecalis SlyA-like transcriptional factor
J.Biol.Chem., 278, 2003
3C99
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BU of 3c99 by Molmil
Structural Basis of Histone H4 Recognition by p55
Descriptor: CADMIUM ION, Chromatin assembly factor 1 p55 subunit
Authors:Song, J.J, Garlick, J.D, Kingston, R.E.
Deposit date:2008-02-15
Release date:2008-05-13
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structural basis of histone H4 recognition by p55.
Genes Dev., 22, 2008
7AX1
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BU of 7ax1 by Molmil
Crystal structure of the human CCR4-CAF1 complex
Descriptor: CCR4-NOT transcription complex subunit 6, CCR4-NOT transcription complex subunit 7, MAGNESIUM ION
Authors:Chen, Y, Khazina, E, Weichenrieder, O.
Deposit date:2020-11-09
Release date:2021-05-12
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Crystal structure and functional properties of the human CCR4-CAF1 deadenylase complex.
Nucleic Acids Res., 49, 2021
5L3X
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BU of 5l3x by Molmil
Crystal structure of negative elongation factor subcomplex NELF-AC
Descriptor: CHLORIDE ION, Negative elongation factor A, Negative elongation factor C/D
Authors:Poellmann, D, Vos, S.M, Cramer, P.
Deposit date:2016-05-24
Release date:2016-06-22
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:Architecture and RNA binding of the human negative elongation factor.
Elife, 5, 2016
4QH7
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BU of 4qh7 by Molmil
LC8 - Ana2 (159-168) Complex
Descriptor: Anastral spindle 2, Dynein light chain 1, cytoplasmic
Authors:Slevin, L.K, Romes, E.R, Slep, K.C.
Deposit date:2014-05-27
Release date:2014-06-11
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.829 Å)
Cite:The Mechanism of Dynein Light Chain LC8-mediated Oligomerization of the Ana2 Centriole Duplication Factor.
J.Biol.Chem., 289, 2014
8VLB
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BU of 8vlb by Molmil
Crystal structure of EloBC-VHL-CDO1 complex bound to compound 4 molecular glue
Descriptor: CITRIC ACID, Cysteine dioxygenase type 1, Elongin-B, ...
Authors:Shu, W, Ma, X, Tutter, A, Buckley, D, Golosov, A, Michaud, G.
Deposit date:2024-01-11
Release date:2024-03-13
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:A small molecule VHL molecular glue degrader for cysteine dioxygenase 1
To Be Published
5K98
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BU of 5k98 by Molmil
Structure of HipA-HipB-O2-O3 complex
Descriptor: Antitoxin HipB, DNA (5'-D(*CP*TP*AP*TP*CP*CP*CP*CP*TP*TP*AP*AP*GP*GP*GP*GP*AP*TP*AP*GP*GP*GP*A)-3'), DNA (5'-D(*TP*CP*CP*CP*TP*AP*TP*CP*CP*CP*CP*TP*TP*AP*AP*GP*GP*GP*GP*AP*TP*AP*G)-3'), ...
Authors:Schumacher, M.
Deposit date:2016-05-31
Release date:2016-06-22
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (3.99 Å)
Cite:HipBA-promoter structures reveal the basis of heritable multidrug tolerance.
Nature, 524, 2015
5LM5
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BU of 5lm5 by Molmil
Structure of C-terminal domain from S. cerevisiae Pat1 decapping activator bound to Dcp2 HLM2 peptide (region 435-451)
Descriptor: DNA topoisomerase 2-associated protein PAT1, mRNA decapping protein 2
Authors:Charenton, C, Gaudon-Plesse, C, Fourati, Z, Taverniti, V, Back, R, Kolesnikova, O, Seraphin, B, Graille, M.
Deposit date:2016-07-29
Release date:2017-08-16
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:A unique surface on Pat1 C-terminal domain directly interacts with Dcp2 decapping enzyme and Xrn1 5'-3' mRNA exonuclease in yeast.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5LMG
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BU of 5lmg by Molmil
Structure of C-terminal domain from S. cerevisiae Pat1 decapping activator bound to Dcp2 HLM10 peptide (region 954-970)
Descriptor: 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, DNA topoisomerase 2-associated protein PAT1, ...
Authors:Charenton, C, Gaudon-Plesse, C, Fourati, Z, Taverniti, V, Back, R, Kolesnikova, O, Seraphin, B, Graille, M.
Deposit date:2016-07-30
Release date:2017-08-16
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.89 Å)
Cite:A unique surface on Pat1 C-terminal domain directly interacts with Dcp2 decapping enzyme and Xrn1 5'-3' mRNA exonuclease in yeast.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5SD9
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BU of 5sd9 by Molmil
Crystal Structure of Dihydrofolate Reductase from Homo sapiens bound to NADP and SDDC Inhibitor SDDC-1096
Descriptor: (2S)-2-[(2-{3-[(2,4-diamino-6-ethylpyrimidin-5-yl)oxy]propoxy}phenyl)methyl]-3-fluoropropanoic acid, 1,2-ETHANEDIOL, Dihydrofolate reductase, ...
Authors:Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2021-12-20
Release date:2022-02-09
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal Structure of Dihydrofolate Reductase from Homo sapiens bound to NADP and SDDC Inhibitor SDDC-1096
to be published
5SDB
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BU of 5sdb by Molmil
Crystal Structure of Human DHFR complexed with NADP and N10-formyl-tetrahydrofolate
Descriptor: 1,2-ETHANEDIOL, Dihydrofolate reductase, N-(4-{[(2,4-diaminopteridin-6-yl)methyl](hydroxymethyl)amino}benzene-1-carbonyl)-L-glutamic acid, ...
Authors:Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2021-12-20
Release date:2022-02-09
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Crystal Structure of Human DHFR complexed with NADP and N10-formyl-tetrahydrofolate
to be published
5SD6
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BU of 5sd6 by Molmil
Crystal Structure of Dihydrofolate Reductase from Homo sapiens bound to NADP and SDDC Inhibitor SDDC-892
Descriptor: 1,2-ETHANEDIOL, 6-ethyl-5-(4-{2-[2-(1H-tetrazol-5-yl)ethyl]phenoxy}butoxy)pyrimidine-2,4-diamine, CHLORIDE ION, ...
Authors:Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2021-12-20
Release date:2022-02-09
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Crystal Structure of Dihydrofolate Reductase from Homo sapiens bound to NADP and SDDC Inhibitor SDDC-892
to be published
8VL9
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BU of 8vl9 by Molmil
Crystal structure of EloBC-VHL-CDO1 complex bound to compound 8 molecular glue
Descriptor: CITRIC ACID, Cysteine dioxygenase type 1, Elongin-B, ...
Authors:Shu, W, Ma, X, Tutter, A, Buckley, D, Golosov, A, Michaud, G.
Deposit date:2024-01-11
Release date:2024-03-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:A small molecule VHL molecular glue degrader for cysteine dioxygenase 1
To Be Published
5SUW
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BU of 5suw by Molmil
Crystal Structure of ToxT from Vibrio Cholerae O395 bound to 3-(8-Methyl-1,2,3,4-tetrahydronaphthalen-1-yl)propanoic acid
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 3-[(1R)-8-methyl-1,2,3,4-tetrahydronaphthalen-1-yl]propanoic acid, TCP pilus virulence regulatory protein
Authors:Kull, F.J, Kelley, A.R.
Deposit date:2016-08-04
Release date:2017-04-12
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal Structure of ToxT from Vibrio Cholerae O395 bound to 3-(8-Methyl-1,2,3,4-tetrahydronaphthalen-1-yl)propanoic acid
To Be Published
5SD8
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BU of 5sd8 by Molmil
Crystal Structure of Dihydrofolate Reductase from Homo sapiens bound to NADP and SDDC Inhibitor SDDC-1190 (racemic mixture)
Descriptor: (2R)-2-[(2-{3-[(2,4-diamino-6-ethylpyrimidin-5-yl)oxy]propoxy}phenyl)methyl]-3,3-difluoropropanoic acid, (2S)-2-[(2-{3-[(2,4-diamino-6-ethylpyrimidin-5-yl)oxy]propoxy}phenyl)methyl]-3,3-difluoropropanoic acid, CHLORIDE ION, ...
Authors:Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2021-12-20
Release date:2022-02-09
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Crystal Structure of Dihydrofolate Reductase from Homo sapiens bound to NADP and SDDC Inhibitor SDDC-1190 (racemic mixture)
to be published
5SDA
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BU of 5sda by Molmil
Crystal Structure of Dihydrofolate Reductase from Homo sapiens bound to NADP and SDDC Inhibitor SDDC-774
Descriptor: (2R)-3-(2-{3-[(2,4-diamino-6-ethylpyrimidin-5-yl)oxy]propoxy}phenyl)-2-methylpropanamide, 1,2-ETHANEDIOL, CHLORIDE ION, ...
Authors:Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2021-12-20
Release date:2022-02-09
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:Crystal Structure of Dihydrofolate Reductase from Homo sapiens bound to NADP and SDDC Inhibitor SDDC-774
to be published

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PDB entries from 2024-11-06

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