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4O8I
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1.45A resolution structure of PEG 400 Bound Cyclophilin D
Descriptor: PENTAETHYLENE GLYCOL, Peptidyl-prolyl cis-trans isomerase F, mitochondrial
Authors:Lovell, S, Valasani, K.R, Battaile, K.P, Wang, C, Yan, S.S.
Deposit date:2013-12-27
Release date:2014-06-11
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:High-resolution crystal structures of two crystal forms of human cyclophilin D in complex with PEG 400 molecules.
Acta Crystallogr F Struct Biol Commun, 70, 2014
4O8H
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0.85A resolution structure of PEG 400 Bound Cyclophilin D
Descriptor: DI(HYDROXYETHYL)ETHER, PENTAETHYLENE GLYCOL, Peptidyl-prolyl cis-trans isomerase F, ...
Authors:Lovell, S, Valasani, K.R, Battaile, K.P, Wang, C, Yan, S.S.
Deposit date:2013-12-27
Release date:2014-06-11
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (0.85 Å)
Cite:High-resolution crystal structures of two crystal forms of human cyclophilin D in complex with PEG 400 molecules.
Acta Crystallogr F Struct Biol Commun, 70, 2014
2MC9
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BU of 2mc9 by Molmil
Cat r 1
Descriptor: Peptidyl-prolyl cis-trans isomerase
Authors:Mueller, G, London, R, Ghosh, D.
Deposit date:2013-08-16
Release date:2014-06-25
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Primary identification, biochemical characterization, and immunologic properties of the allergenic pollen cyclophilin cat R 1.
J.Biol.Chem., 289, 2014
4TOT
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BU of 4tot by Molmil
Crystal structure of rat cyclophilin D in complex with a potent nonimmunosuppressive inhibitor
Descriptor: HEXAETHYLENE GLYCOL, Peptidyl-prolyl cis-trans isomerase F, mitochondrial, ...
Authors:Knapp, M.S, Elling, R.A.
Deposit date:2014-06-06
Release date:2014-11-12
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.39 Å)
Cite:Potent nonimmunosuppressive cyclophilin inhibitors with improved pharmaceutical properties and decreased transporter inhibition.
J.Med.Chem., 57, 2014
4R3E
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BU of 4r3e by Molmil
Structure of the spliceosomal peptidyl-prolyl cis-trans isomerase Cwc27 from Homo sapiens
Descriptor: GLYCEROL, Peptidyl-prolyl cis-trans isomerase CWC27 homolog
Authors:Ulrich, A, Wahl, M.C.
Deposit date:2014-08-15
Release date:2014-11-19
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structure and evolution of the spliceosomal peptidyl-prolyl cis-trans isomerase Cwc27.
Acta Crystallogr.,Sect.D, 70, 2014
4R3F
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BU of 4r3f by Molmil
Structure of the spliceosomal peptidyl-prolyl cis-trans isomerase Cwc27 from Chaetomium thermophilum
Descriptor: 1,2-ETHANEDIOL, 3,6,9,12,15,18,21,24-OCTAOXAHEXACOSAN-1-OL, ACETATE ION, ...
Authors:Ulrich, A, Wahl, M.C.
Deposit date:2014-08-15
Release date:2014-11-19
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:Structure and evolution of the spliceosomal peptidyl-prolyl cis-trans isomerase Cwc27.
Acta Crystallogr.,Sect.D, 70, 2014
4S1J
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BU of 4s1j by Molmil
Crystal structure of cyclophilin mutant V33A from Leishmania donovani at 2.3 angstrom.
Descriptor: Peptidyl-prolyl cis-trans isomerase
Authors:Roy, S, Datta, A.K, Banerjee, R.
Deposit date:2015-01-14
Release date:2015-03-04
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Characterization and prediction of thermal stability of cyclophilin mutants from L.donovani
To be Published
4S1E
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BU of 4s1e by Molmil
Crystal structure of cyclophilin mutant L120A from Leishmania donovani at 2.22 angstrom.
Descriptor: Peptidyl-prolyl cis-trans isomerase
Authors:Roy, S, Datta, A.K, Banerjee, R.
Deposit date:2015-01-13
Release date:2015-03-11
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.22 Å)
Cite:Characterization and prediction of thermal stability of cyclophilin mutants from L.donovani
To be Published
2MZU
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BU of 2mzu by Molmil
Extending the eNOE data set of large proteins by evaluation of NOEs with unresolved diagonals
Descriptor: Peptidyl-prolyl cis-trans isomerase A
Authors:Chi, C.N, Strotz, D, Riek, R, Voegeli, B.
Deposit date:2015-02-24
Release date:2015-04-22
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Extending the eNOE data set of large proteins by evaluation of NOEs with unresolved diagonals.
J.Biomol.Nmr, 62, 2015
4YUO
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BU of 4yuo by Molmil
High-resolution multiconformer synchrotron model of CypA at 273 K
Descriptor: Peptidyl-prolyl cis-trans isomerase A
Authors:Keedy, D.A, Kenner, L.R, Warkentin, M, Woldeyes, R.A, Thompson, M.C, Brewster, A.S, Van Benschoten, A.H, Baxter, E.L, Hopkins, J.B, Uervirojnangkoorn, M, McPhillips, S.E, Song, J, Mori, R.A, Holton, J.M, Weis, W.I, Brunger, A.T, Soltis, M, Lemke, H, Gonzalez, A, Sauter, N.K, Cohen, A.E, van den Bedem, H, Thorne, R.E, Fraser, J.S.
Deposit date:2015-03-18
Release date:2015-05-20
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.2 Å)
Cite:Mapping the conformational landscape of a dynamic enzyme by multitemperature and XFEL crystallography.
Elife, 4, 2015
2MVZ
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BU of 2mvz by Molmil
Solution Structure for Cyclophilin A from Geobacillus Kaustophilus
Descriptor: Peptidyl-prolyl cis-trans isomerase
Authors:Holliday, M.J, Isern, N.G, Geoffrey, A.S, Zhang, F, Eisenmesser, E.Z.
Deposit date:2014-10-20
Release date:2015-07-08
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:Structure and Dynamics of GeoCyp: A Thermophilic Cyclophilin with a Novel Substrate Binding Mechanism That Functions Efficiently at Low Temperatures.
Biochemistry, 54, 2015
4XNC
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BU of 4xnc by Molmil
Crystal structure at room temperature of cyclophilin D in complex with an inhibitor
Descriptor: Peptidyl-prolyl cis-trans isomerase F, mitochondrial, ethyl N-[(4-aminobenzyl)carbamoyl]glycinate
Authors:Gelin, M, Allemand, F, Labesse, G, Guichou, J.F.
Deposit date:2015-01-15
Release date:2015-08-12
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.23 Å)
Cite:Combining `dry' co-crystallization and in situ diffraction to facilitate ligand screening by X-ray crystallography.
Acta Crystallogr.,Sect.D, 71, 2015
4N1P
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BU of 4n1p by Molmil
Structure of Cyclophilin A in complex with Picolinamide.
Descriptor: Peptidyl-prolyl cis-trans isomerase A, pyridine-2-carboxamide
Authors:Mcnae, I.W, Dornan, J, Walkinshaw, M.D.
Deposit date:2013-10-04
Release date:2015-08-12
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Mapping the binding surface of Cyclophilin A.
To be Published
4N1S
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BU of 4n1s by Molmil
Structure of Cyclophilin A in complex with benzohydrazide.
Descriptor: Peptidyl-prolyl cis-trans isomerase A, benzohydrazide
Authors:Mcnae, I.W, Dornan, J, Walkinshaw, M.D.
Deposit date:2013-10-04
Release date:2015-08-12
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.47 Å)
Cite:Mapping the binding surface of Cyclophilin A.
To be Published
4ZSD
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BU of 4zsd by Molmil
Human Cyclophilin D Complexed with an Inhibitor at room temperature
Descriptor: 1-(4-aminobenzyl)-3-[(2S)-4-(methylsulfanyl)-1-{(2R)-2-[2-(methylsulfanyl)phenyl]pyrrolidin-1-yl}-1-oxobutan-2-yl]urea, Peptidyl-prolyl cis-trans isomerase F, mitochondrial
Authors:Gelin, M, Delfosse, V, Allemand, F, Hoh, F, Sallaz-Damaz, Y, Pirocchi, M, Bourguet, W, Ferrer, J.-L, Labesse, G, Guichou, J.-F.
Deposit date:2015-05-13
Release date:2015-08-12
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:Combining `dry' co-crystallization and in situ diffraction to facilitate ligand screening by X-ray crystallography.
Acta Crystallogr.,Sect.D, 71, 2015
4N1M
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BU of 4n1m by Molmil
Structure of Cyclophilin A in complex with GlyPro.
Descriptor: GLYCINE, PROLINE, Peptidyl-prolyl cis-trans isomerase A
Authors:Mcnae, I.W, Patterson, A, Walkinshaw, M.D.
Deposit date:2013-10-04
Release date:2015-08-12
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (1.15 Å)
Cite:Mapping the binding surface of Cyclophilin A.
To be Published
4N1N
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BU of 4n1n by Molmil
Structure of Cyclophilin A in complex with Benzamide.
Descriptor: BENZAMIDE, Peptidyl-prolyl cis-trans isomerase A
Authors:Mcnae, I.W, Dornan, J, Walkinshaw, M.D.
Deposit date:2013-10-04
Release date:2015-08-12
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Mapping the binding surface of Cyclophilin A.
To be Published
4ZSC
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BU of 4zsc by Molmil
Human Cyclophilin D Complexed with an Inhibitor at room temperature
Descriptor: Peptidyl-prolyl cis-trans isomerase F, mitochondrial, ethyl N-[(4-aminobenzyl)carbamoyl]glycinate
Authors:Gelin, M, Delfosse, V, Allemand, F, Hoh, F, Sallaz-Damaz, Y, Pirocchi, M, Bourguet, W, Ferrer, J.-L, Labesse, G, Guichou, J.-F.
Deposit date:2015-05-13
Release date:2015-08-12
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Combining `dry' co-crystallization and in situ diffraction to facilitate ligand screening by X-ray crystallography.
Acta Crystallogr.,Sect.D, 71, 2015
4N1O
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BU of 4n1o by Molmil
Structure of Cyclophilin A in complex with Saccharin.
Descriptor: 1,2-BENZISOTHIAZOL-3(2H)-ONE 1,1-DIOXIDE, Peptidyl-prolyl cis-trans isomerase A
Authors:Mcnae, I.W, Dornan, J, Walkinshaw, M.D.
Deposit date:2013-10-04
Release date:2015-08-12
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Mapping the binding surface of Cyclophilin A.
To be Published
4N1R
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BU of 4n1r by Molmil
Structure of Cyclophilin A in complex with benzenesulfonohydrazide.
Descriptor: Peptidyl-prolyl cis-trans isomerase A, benzenesulfonohydrazide
Authors:Mcnae, I.W, Dornan, J, Walkinshaw, M.D.
Deposit date:2013-10-04
Release date:2015-08-12
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Mapping the binding surface of Cyclophilin A.
To be Published
4N1Q
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BU of 4n1q by Molmil
Structure of Cyclophilin A in complex with cyclohexanecarboxamide.
Descriptor: Peptidyl-prolyl cis-trans isomerase A, cyclohexanecarboxamide
Authors:Mcnae, I.W, Dornan, J, Walkinshaw, M.D.
Deposit date:2013-10-04
Release date:2015-08-12
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Mapping the binding surface of Cyclophilin A.
To be Published
2N0T
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BU of 2n0t by Molmil
Structural ensemble of the enzyme cyclophilin reveals an orchestrated mode of action at atomic resolution
Descriptor: Peptidyl-prolyl cis-trans isomerase A
Authors:Chi, C.N, Voegeli, B, Bibow, S, Strotz, D, Orts, J, Guntert, P, Riek, R.
Deposit date:2015-03-13
Release date:2015-08-26
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:A Structural Ensemble for the Enzyme Cyclophilin Reveals an Orchestrated Mode of Action at Atomic Resolution.
Angew.Chem.Int.Ed.Engl., 54, 2015
2MS4
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BU of 2ms4 by Molmil
Cyclophilin a complexed with a fragment of crk-ii
Descriptor: Peptide, Peptidyl-prolyl cis-trans isomerase A
Authors:Jankowski, W, Saleh, T, Rossi, P, Kalodimos, C.
Deposit date:2014-07-22
Release date:2015-09-09
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:Cyclophilin A promotes cell migration via the Abl-Crk signaling pathway.
Nat.Chem.Biol., 12, 2016
3JB9
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BU of 3jb9 by Molmil
Cryo-EM structure of the yeast spliceosome at 3.6 angstrom resolution
Descriptor: ADENOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ...
Authors:Yan, C, Hang, J, Wan, R, Huang, M, Wong, C, Shi, Y.
Deposit date:2015-08-09
Release date:2015-09-23
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Structure of a yeast spliceosome at 3.6-angstrom resolution
Science, 349, 2015
4YUK
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BU of 4yuk by Molmil
Multiconformer synchrotron model of CypA at 260 K
Descriptor: Peptidyl-prolyl cis-trans isomerase A
Authors:Keedy, D.A, Kenner, L.R, Warkentin, M, Woldeyes, R.A, Thompson, M.C, Brewster, A.S, Van Benschoten, A.H, Baxter, E.L, Hopkins, J.B, Uervirojnangkoorn, M, McPhillips, S.E, Song, J, Mori, R.A, Holton, J.M, Weis, W.I, Brunger, A.T, Soltis, M, Lemke, H, Gonzalez, A, Sauter, N.K, Cohen, A.E, van den Bedem, H, Thorne, R.E, Fraser, J.S.
Deposit date:2015-03-18
Release date:2015-10-14
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.48 Å)
Cite:Mapping the conformational landscape of a dynamic enzyme by multitemperature and XFEL crystallography.
Elife, 4, 2015

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