4ZSD

Human Cyclophilin D Complexed with an Inhibitor at room temperature

Summary for 4ZSD

Entry DOI	10.2210/pdb4zsd/pdb
Related	4J5C
Descriptor	Peptidyl-prolyl cis-trans isomerase F, mitochondrial, 1-(4-aminobenzyl)-3-[(2S)-4-(methylsulfanyl)-1-{(2R)-2-[2-(methylsulfanyl)phenyl]pyrrolidin-1-yl}-1-oxobutan-2-yl]urea (3 entities in total)
Functional Keywords	isomerase inhibitor complex, isomerase
Biological source	Homo sapiens (Human)
Cellular location	Mitochondrion matrix : P30405
Total number of polymer chains	1
Total formula weight	18124.79
Authors	Gelin, M.,Delfosse, V.,Allemand, F.,Hoh, F.,Sallaz-Damaz, Y.,Pirocchi, M.,Bourguet, W.,Ferrer, J.-L.,Labesse, G.,Guichou, J.-F. (deposition date: 2015-05-13, release date: 2015-08-12, Last modification date: 2015-08-19)
Primary citation	Gelin, M.,Delfosse, V.,Allemand, F.,Hoh, F.,Sallaz-Damaz, Y.,Pirocchi, M.,Bourguet, W.,Ferrer, J.L.,Labesse, G.,Guichou, J.F. Combining `dry' co-crystallization and in situ diffraction to facilitate ligand screening by X-ray crystallography. Acta Crystallogr.,Sect.D, 71:1777-1787, 2015 Cited by PubMed: 26249358 DOI: 10.1107/S1399004715010342 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.45 Å)

Structure validation