PDB: 48062 resultsInfo pagesStatus searchChemie searchBIRD

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4K2H	Crystal structure of C103A mutant of DJ-1 superfamily protein STM1931 from Salmonella typhimurium Descriptor: Intracellular protease/amidase, ZINC ION Authors: Shumilin, I.A, Niedzialkowska, E, Domagalski, M.J, Stam, J, Anderson, W.F, Minor, W, Center for Structural Genomics of Infectious Diseases (CSGID) Deposit date: 2013-04-09 Release date: 2013-04-24 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Crystal structure of C103A mutant of DJ-1 superfamily protein STM1931 from Salmonella typhimurium TO BE PUBLISHED
4KJZ	Crystal Structure of Thermus Thermophilus IF2, Apo and GDP-bound Forms (2-474) Descriptor: GUANOSINE-5'-DIPHOSPHATE, Translation initiation factor IF-2 Authors: Eiler, D.R, Lin, J, Steitz, T.A. Deposit date: 2013-05-04 Release date: 2013-09-11 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (2.8 Å) Cite: Initiation factor 2 crystal structure reveals a different domain organization from eukaryotic initiation factor 5B and mechanism among translational GTPases. Proc.Natl.Acad.Sci.USA, 110, 2013
4KLX	Crystal structure of dihydrofolate reductase from Mycobacterium tuberculosis in an open conformation. Descriptor: 2'-MONOPHOSPHOADENOSINE-5'-DIPHOSPHATE, 2-{2-[2-2-(METHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, Dihydrofolate reductase Authors: Dias, M.V.B, Tyrakis, P, Blundell, T.L. Deposit date: 2013-05-07 Release date: 2013-12-25 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (1.23 Å) Cite: Mycobacterium tuberculosis Dihydrofolate Reductase Reveals Two Conformational States and a Possible Low Affinity Mechanism to Antifolate Drugs. Structure, 22, 2014
4K2Z	Crystal structure of the complex of type I Ribosome inactivating protein from Momordica balsamina with Methylethylamine at 1.80 A resolution Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, METHYLETHYLAMINE, ... Authors: Yamini, S, Pandey, S, Kushwaha, G.S, Sinha, M, Kaur, P, Sharma, S, Singh, T.P. Deposit date: 2013-04-10 Release date: 2013-05-01 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Crystal structure of the complex of type I Ribosome inactivating protein from Momordica balsamina with Methylethylamine at 1.80 A resolution To be Published
4KRA	Salmonella typhi OmpF complex with Ciprofloxacin Descriptor: 1-CYCLOPROPYL-6-FLUORO-4-OXO-7-PIPERAZIN-1-YL-1,4-DIHYDROQUINOLINE-3-CARBOXYLIC ACID, Outer membrane protein F Authors: Madhuranayaki, T, Balasubramaniam, D, Krishnaswamy, S. Deposit date: 2013-05-16 Release date: 2014-05-28 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (3.32 Å) Cite: Salmonella typhi OmpF complex with Ciprofloxacin To be published
4KSL	Gumby/Fam105B in complex with linear di-ubiquitin Descriptor: Polyubiquitin-C, Protein FAM105B Authors: Juang, Y.-C, Ceccarelli, D.F, Sicheri, F. Deposit date: 2013-05-17 Release date: 2013-06-05 Last modified: 2024-04-03 Method: X-RAY DIFFRACTION (2.83 Å) Cite: The linear ubiquitin-specific deubiquitinase gumby regulates angiogenesis. Nature, 498, 2013
4K5U	Recognition of the BG-H Antigen by a Lamprey Variable Lymphocyte Receptor Descriptor: Variable lymphocyte receptor, beta-D-galactopyranose Authors: Luo, M, Velikovsky, C.A, Yang, X.B, Mariuzza, R.A. Deposit date: 2013-04-15 Release date: 2013-06-26 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (1.698 Å) Cite: Recognition of the thomsen-friedenreich pancarcinoma carbohydrate antigen by a lamprey variable lymphocyte receptor. J.Biol.Chem., 288, 2013
4KDF	Crystal Structure of Thermus thermophilus Malate Dehydrogenase in Complex with NAD Descriptor: Malate dehydrogenase, SULFATE ION Authors: Hsu, C.-H, Hong, C.-H, Chang, Y.-Y. Deposit date: 2013-04-25 Release date: 2014-02-05 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (2.356 Å) Cite: Crystal structures and molecular dynamics simulations of thermophilic malate dehydrogenase reveal critical loop motion for co-substrate binding. Plos One, 8, 2013
4K9F	Neutron structure of Perdeuterated Rubredoxin refined against 1.75 resolution data collected on the new IMAGINE instrument at HFIR, ORNL Descriptor: FE (III) ION, Rubredoxin Authors: Munshi, P, Meilleur, F, Myles, D. Deposit date: 2013-04-19 Release date: 2013-12-04 Last modified: 2023-09-20 Method: NEUTRON DIFFRACTION (1.75 Å) Cite: The IMAGINE instrument: first neutron protein structure and new capabilities for neutron macromolecular crystallography. Acta Crystallogr.,Sect.D, 69, 2013
4KHM	HCV NS5B GT1A with GSK5852 Descriptor: HCV Polymerase, SULFATE ION, [4-({[5-cyclopropyl-2-(4-fluorophenyl)-3-(methylcarbamoyl)-1-benzofuran-6-yl](methylsulfonyl)amino}methyl)-2-fluorophenyl]boronic acid Authors: Williams, S.P, Kahler, K.M, Shotwell, J.B. Deposit date: 2013-04-30 Release date: 2013-05-15 Last modified: 2024-03-13 Method: X-RAY DIFFRACTION (1.7 Å) Cite: Discovery of a Potent Boronic Acid Derived Inhibitor of the HCV RNA-Dependent RNA Polymerase. J.Med.Chem., 57, 2014
4KIV	RECOMBINANT KRINGLE IV-10/W72R MUTANT OF HUMAN APOLIPOPROTEIN(A) Descriptor: APOLIPOPROTEIN Authors: Mochalkin, I, Tulinsky, A, Scanu, A. Deposit date: 1998-08-26 Release date: 1999-05-18 Last modified: 2018-03-14 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Recombinant kringle IV-10 modules of human apolipoprotein(a): structure, ligand binding modes, and biological relevance. Biochemistry, 38, 1999
4KFE	Crystal structure of Hansenula polymorpha copper amine oxidase-1 reduced by methylamine at pH 7.0 Descriptor: COPPER (II) ION, FORMYL GROUP, GLYCEROL, ... Authors: Johnson, B.J, Yukl, E.T, Klema, V.J, Wilmot, C.M. Deposit date: 2013-04-26 Release date: 2013-08-21 Last modified: 2024-10-16 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Structural evidence for the semiquinone in a copper amine oxidase from Hansenula polymorpha: implications for the catalytic mechanism J.Biol.Chem., 2013
4KI4	Ternary complex of rb69 mutant L415F with ribonucleotides at 0 and -1 position Descriptor: CALCIUM ION, DNA (5'-D(*GP*CP*GP*GP*AP*CP*TP*GP*CP*TP*TP*AP*CP*C)-3'), DNA polymerase, ... Authors: Clausen, A.R, Pedersen, L.C. Deposit date: 2013-05-01 Release date: 2013-10-09 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (2.45 Å) Cite: Structure-function analysis of ribonucleotide bypass by B family DNA replicases. Proc.Natl.Acad.Sci.USA, 110, 2013
4KKD	The X-ray crystal structure of Mannose-binding lectin-associated serine proteinase-3 reveals the structural basis for enzyme inactivity associated with the 3MC syndrome Descriptor: IMIDAZOLE, Mannan-binding lectin serine protease 1 Authors: Yongqing, T, Wilmann, P.G, Reeve, S.B, Coetzer, T.H, Smith, A.I, Whisstock, J.C, Pike, R.N, Wijeyewickrema, L.C. Deposit date: 2013-05-05 Release date: 2013-07-03 Last modified: 2024-10-09 Method: X-RAY DIFFRACTION (2.5991 Å) Cite: The X-ray Crystal Structure of Mannose-binding Lectin-associated Serine Proteinase-3 Reveals the Structural Basis for Enzyme Inactivity Associated with the Carnevale, Mingarelli, Malpuech, and Michels (3MC) Syndrome. J.Biol.Chem., 288, 2013
4KKX	Crystal structure of Tryptophan Synthase from Salmonella typhimurium with 2-aminophenol quinonoid in the beta site and the F6 inhibitor in the alpha site Descriptor: 1,2-ETHANEDIOL, 2-{[4-(TRIFLUOROMETHOXY)BENZOYL]AMINO}ETHYL DIHYDROGEN PHOSPHATE, DI(HYDROXYETHYL)ETHER, ... Authors: Hilario, E, Niks, D, Dunn, M.F, Mueller, L.J, Fan, L. Deposit date: 2013-05-06 Release date: 2014-01-01 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (1.77 Å) Cite: Allostery and substrate channeling in the tryptophan synthase bienzyme complex: evidence for two subunit conformations and four quaternary states. Biochemistry, 52, 2013
4KQA	Crystal structure of the golgi casein kinase Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, NICKEL (II) ION, Protein H03A11.1, ... Authors: Xiao, J. Deposit date: 2013-05-14 Release date: 2013-06-26 Last modified: 2020-07-29 Method: X-RAY DIFFRACTION (2.603 Å) Cite: Crystal structure of the Golgi casein kinase. Proc.Natl.Acad.Sci.USA, 110, 2013
4KLN	Structure of p97 N-D1 A232E mutant in complex with ATPgS Descriptor: MAGNESIUM ION, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, Transitional endoplasmic reticulum ATPase Authors: Xia, D, Tang, W.K. Deposit date: 2013-05-07 Release date: 2013-11-13 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (2.62 Å) Cite: Altered Intersubunit Communication Is the Molecular Basis for Functional Defects of Pathogenic p97 Mutants. J.Biol.Chem., 288, 2013
4K4I	Ternary crystal structures of a human DNA POLYMERASE LAMBDA IN COMPLEX WITH DNA AND (-)FTC-TP. Descriptor: ACETATE ION, CACODYLATE ION, CALCIUM ION, ... Authors: Vyas, R, Suo, Z. Deposit date: 2013-04-12 Release date: 2014-07-16 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (2.25 Å) Cite: Structural basis for the binding and incorporation of nucleotide analogs with L-stereochemistry by human DNA polymerase lambda. Proc.Natl.Acad.Sci.USA, 111, 2014
4K5I	Structure of bovine endothelial nitric oxide synthase heme domain in complex with (R)-1,2-bis((2-amino-4-methylpyridin-6-yl)-methoxy)-propan-3-amine Descriptor: 5,6,7,8-TETRAHYDROBIOPTERIN, 6,6'-{[(2R)-3-aminopropane-1,2-diyl]bis(oxymethanediyl)}bis(4-methylpyridin-2-amine), ACETATE ION, ... Authors: Li, H, Poulos, T.L. Deposit date: 2013-04-14 Release date: 2013-09-18 Last modified: 2024-10-16 Method: X-RAY DIFFRACTION (2.08 Å) Cite: Chiral linkers to improve selectivity of double-headed neuronal nitric oxide synthase inhibitors. Bioorg.Med.Chem.Lett., 23, 2013
4K4G	Ternary crystal structures of human DNA POLYMERASE LAMBDA IN COMPLEX WITH DNA AND L-DCTP. Descriptor: 4-amino-1-{2-deoxy-5-O-[(R)-hydroxy{[(S)-hydroxy(phosphonooxy)phosphoryl]oxy}phosphoryl]-beta-L-erythro-pentofuranosyl}pyrimidin-2(1H)-one, ACETATE ION, CACODYLATE ION, ... Authors: Vyas, R, Suo, Z. Deposit date: 2013-04-12 Release date: 2014-07-16 Last modified: 2024-03-13 Method: X-RAY DIFFRACTION (2.15 Å) Cite: Structural basis for the binding and incorporation of nucleotide analogs with L-stereochemistry by human DNA polymerase lambda. Proc.Natl.Acad.Sci.USA, 111, 2014
4K95	Crystal Structure of Parkin Descriptor: E3 ubiquitin-protein ligase parkin, ZINC ION Authors: Seirafi, M, Menade, M, Sauve, V, Kozlov, G, Trempe, J.-F, Nagar, B, Gehring, K. Deposit date: 2013-04-19 Release date: 2013-05-15 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (6.499 Å) Cite: Structure of parkin reveals mechanisms for ubiquitin ligase activation. Science, 340, 2013
4KB3	Crystal structure of the mitochondrial peroxiredoxin from Leishmania braziliensis in the decameric form Descriptor: Peroxidoxin Authors: Giuseppe, P.O, Souza, T.A.C.B, Morais, M.A.B, Murakami, M.T. Deposit date: 2013-04-23 Release date: 2014-05-14 Method: X-RAY DIFFRACTION (2.93 Å) Cite: Crystal structure of the mitochondrial peroxiredoxin from Leishmania braziliensis in the decameric form To be Published
4KBZ	Crystal Structure of Hypoxia-Inducible Factor Prolyl Hydroxylase (PHD2) with (S)-{2-[2-(5-Cyano-3-hydroxy-pyridin-2-yl)-thiazol-4-yl]-acetylamino}-phenyl-acetic acid Descriptor: (2S)-({[2-(5-cyano-3-hydroxypyridin-2-yl)-1,3-thiazol-4-yl]acetyl}amino)(phenyl)ethanoic acid, Egl nine homolog 1, FE (II) ION, ... Authors: Kim, H.T, Hong, Y.R, Chang, H.J. Deposit date: 2013-04-24 Release date: 2013-05-15 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (2.15 Å) Cite:
4KC5	Crystal structure of the C-terminal part of RhiE from Burkholderia rhizoxinica Descriptor: GLYCEROL, RhiE protein Authors: Zocher, G, Heim, J.B, Stehle, T. Deposit date: 2013-04-24 Release date: 2013-09-18 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (2.14 Å) Cite: Vinylogous chain branching catalysed by a dedicated polyketide synthase module. Nature, 502, 2013
4KFQ	Crystal structure of the NMDA receptor GluN1 ligand binding domain in complex with 1-thioxo-1,2-dihydro-[1,2,4]triazolo[4,3-a]quinoxalin-4(5H)-one Descriptor: 1-sulfanyl[1,2,4]triazolo[4,3-a]quinoxalin-4(5H)-one, GLYCEROL, Glutamate receptor ionotropic, ... Authors: Steffensen, T.B, Tabrizi, F.M, Gajhede, M, Kastrup, J.S. Deposit date: 2013-04-27 Release date: 2013-10-09 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Crystal structure and pharmacological characterization of a novel N-methyl-D-aspartate (NMDA) receptor antagonist at the GluN1 glycine binding site. J.Biol.Chem., 288, 2013

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