4KKD

The X-ray crystal structure of Mannose-binding lectin-associated serine proteinase-3 reveals the structural basis for enzyme inactivity associated with the 3MC syndrome

Summary for 4KKD

Entry DOI	10.2210/pdb4kkd/pdb
Descriptor	Mannan-binding lectin serine protease 1, IMIDAZOLE (3 entities in total)
Functional Keywords	protease, chymotrypsin fold, secreted, hydrolase
Biological source	Homo sapiens (human)
Cellular location	Secreted: P48740
Total number of polymer chains	2
Total formula weight	96083.70
Authors	Yongqing, T.,Wilmann, P.G.,Reeve, S.B.,Coetzer, T.H.,Smith, A.I.,Whisstock, J.C.,Pike, R.N.,Wijeyewickrema, L.C. (deposition date: 2013-05-05, release date: 2013-07-03, Last modification date: 2013-08-21)
Primary citation	Yongqing, T.,Wilmann, P.G.,Reeve, S.B.,Coetzer, T.H.,Smith, A.I.,Whisstock, J.C.,Pike, R.N.,Wijeyewickrema, L.C. The X-ray Crystal Structure of Mannose-binding Lectin-associated Serine Proteinase-3 Reveals the Structural Basis for Enzyme Inactivity Associated with the Carnevale, Mingarelli, Malpuech, and Michels (3MC) Syndrome. J.Biol.Chem., 288:22399-22407, 2013 Cited by PubMed: 23792966 DOI: 10.1074/jbc.M113.483875 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.5991 Å)

Structure validation