4KBZ

Crystal Structure of Hypoxia-Inducible Factor Prolyl Hydroxylase (PHD2) with (S)-{2-[2-(5-Cyano-3-hydroxy-pyridin-2-yl)-thiazol-4-yl]-acetylamino}-phenyl-acetic acid

Summary for 4KBZ

• Entry DOI: 10.2210/pdb4kbz/pdb
• Related: 2G19 2G1M 2HBU
• Descriptor: Egl nine homolog 1, (2S)-({[2-(5-cyano-3-hydroxypyridin-2-yl)-1,3-thiazol-4-yl]acetyl}amino)(phenyl)ethanoic acid, FE (II) ION, ... (5 entities in total)
• Functional Keywords: jelly-roll beta-strand core, oxidoreductase, hif
• Biological source: Homo sapiens (human)
• Cellular location: Cytoplasm: Q9GZT9
• Total number of polymer chains: 1
• Total formula weight: 27419.81

Authors

Kim, H.T.,Hong, Y.R.,Chang, H.J. (deposition date: 2013-04-24, release date: 2013-05-15, Last modification date: 2023-09-20)

• Primary citation: ; ,

Experimental method

X-RAY DIFFRACTION (2.15 Å)