2HBU
Crystal structure of HIF prolyl hydroxylase EGLN-1 in complex with a biologically active inhibitor
Summary for 2HBU
Entry DOI | 10.2210/pdb2hbu/pdb |
Related | 2HBT |
Descriptor | Egl nine homolog 1, FE (II) ION, N-[(1-CHLORO-4-HYDROXYISOQUINOLIN-3-YL)CARBONYL]GLYCINE, ... (4 entities in total) |
Functional Keywords | hif, prolyl hydroxylase, egln, 2-oxoglutarate, hypoxia inducible factor, oxidoreductase |
Biological source | Homo sapiens (human) |
Cellular location | Cytoplasm : Q9GZT9 |
Total number of polymer chains | 1 |
Total formula weight | 28169.18 |
Authors | Evdokimov, A.G.,Walter, R.L.,Mekel, M.,Pokross, M.E.,Kawamoto, R.,Boyer, A. (deposition date: 2006-06-14, release date: 2006-06-27, Last modification date: 2023-08-30) |
Primary citation | Evdokimov, A.G.,Walter, R.L.,Mekel, M.,Pokross, M.E.,Kawamoto, R.,Boyer, A. Crystal structure of HIF prolyl hydroxylase in complex with a biologically active inhibitor To be Published, |
Experimental method | X-RAY DIFFRACTION (1.85 Å) |
Structure validation
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