7O4R
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![BU of 7o4r by Molmil](/molmil-images/mine/7o4r) | Structure of Mycobacterium tuberculosis beta-oxidation trifunctional enzyme with Coenzyme A bound at the thiolase active sites and additional binding site (CoA(HAD/KAT)) | Descriptor: | 3-hydroxyacyl-CoA dehydrogenase, COENZYME A, GLYCEROL, ... | Authors: | Dalwani, S, Wierenga, R.K, Venkatesan, R. | Deposit date: | 2021-04-07 | Release date: | 2021-08-25 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.79 Å) | Cite: | Substrate specificity and conformational flexibility properties of the Mycobacterium tuberculosis beta-oxidation trifunctional enzyme. J.Struct.Biol., 213, 2021
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1ZL5
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![BU of 1zl5 by Molmil](/molmil-images/mine/1zl5) | Crystal structure of Glu335Gln mutant of Clostridium botulinum neurotoxin E catalytic domain | Descriptor: | CHLORIDE ION, botulinum neurotoxin type E | Authors: | Agarwal, R, Binz, T, Swaminathan, S. | Deposit date: | 2005-05-05 | Release date: | 2005-07-05 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Analysis of Active Site Residues of Botulinum Neurotoxin E by Mutational, Functional, and Structural Studies: Glu335Gln Is an Apoenzyme. Biochemistry, 44, 2005
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2E9X
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![BU of 2e9x by Molmil](/molmil-images/mine/2e9x) | The crystal structure of human GINS core complex | Descriptor: | DNA replication complex GINS protein PSF1, DNA replication complex GINS protein PSF2, GINS complex subunit 3, ... | Authors: | Kamada, K, Hanaoka, F. | Deposit date: | 2007-01-27 | Release date: | 2007-04-10 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structure of the human GINS complex and its assembly and functional interface in replication initiation Nat.Struct.Mol.Biol., 14, 2007
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3HNK
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![BU of 3hnk by Molmil](/molmil-images/mine/3hnk) | Crystal structure of the dimeric assembly of the cyt cb562 variant RIDC-1 | Descriptor: | PROTOPORPHYRIN IX CONTAINING FE, Soluble cytochrome b562 | Authors: | Salgado, E.N, Lewis, R.A, Brodin, J, Tezcan, F.A. | Deposit date: | 2009-05-31 | Release date: | 2010-02-09 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Metal templated design of protein interfaces. Proc.Natl.Acad.Sci.USA, 107, 2010
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7A0L
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![BU of 7a0l by Molmil](/molmil-images/mine/7a0l) | Joint neutron/X-ray room temperature structure of perdeuterated Aspergillus flavus urate oxidase in complex with the 8-azaxanthine inhibitor and catalytic water bound in the peroxo hole | Descriptor: | 8-AZAXANTHINE, SODIUM ION, Uricase | Authors: | McGregor, L, Bui, S, Blakeley, M.P, Steiner, R.A. | Deposit date: | 2020-08-09 | Release date: | 2020-12-09 | Last modified: | 2024-05-01 | Method: | NEUTRON DIFFRACTION (1.33 Å), X-RAY DIFFRACTION | Cite: | Joint neutron/X-ray crystal structure of a mechanistically relevant complex of perdeuterated urate oxidase and simulations provide insight into the hydration step of catalysis. Iucrj, 8, 2021
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5VBX
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![BU of 5vbx by Molmil](/molmil-images/mine/5vbx) | Crystal structure of holo-[acyl-carrier-protein] synthase (AcpS) from Escherichia coli | Descriptor: | 1,2-ETHANEDIOL, Holo-[acyl-carrier-protein] synthase, SODIUM ION | Authors: | Marcella, A.M, Barb, A.W. | Deposit date: | 2017-03-30 | Release date: | 2017-11-01 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | Structure, High Affinity, and Negative Cooperativity of the Escherichia coli Holo-(Acyl Carrier Protein):Holo-(Acyl Carrier Protein) Synthase Complex. J. Mol. Biol., 429, 2017
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5VCF
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![BU of 5vcf by Molmil](/molmil-images/mine/5vcf) | RNA hairpin structure containing tetraloop/receptor motif, complexed with 2-MeImpG analogue | Descriptor: | 5'-O-[(S)-hydroxy(4-methyl-1H-imidazol-5-yl)phosphoryl]guanosine, RNA (5'-R(*CP*UP*AP*UP*GP*CP*CP*UP*GP*CP*UP*G)-3'), RNA (5'-R(*CP*UP*GP*CP*UP*GP*GP*CP*UP*AP*AP*GP*GP*CP*CP*CP*GP*AP*AP*AP*GP*G)-3') | Authors: | Zhang, W, Szostak, J.W. | Deposit date: | 2017-03-31 | Release date: | 2018-02-21 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Structural Rationale for the Enhanced Catalysis of Nonenzymatic RNA Primer Extension by a Downstream Oligonucleotide. J. Am. Chem. Soc., 140, 2018
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5X5I
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![BU of 5x5i by Molmil](/molmil-images/mine/5x5i) | The X-ray crystal structure of a TetR family transcription regulator RcdA involved in the regulation of biofilm formation in Escherichia coli | Descriptor: | HTH-type transcriptional regulator RcdA | Authors: | Sugino, H, Usui, M, Shimada, T, Nakano, M, Ogasawara, H, Ishihama, A, Hirata, A. | Deposit date: | 2017-02-16 | Release date: | 2017-12-27 | Method: | X-RAY DIFFRACTION (2.554 Å) | Cite: | A structural sketch of RcdA, a transcription factor controlling the master regulator of biofilm formation. FEBS Lett., 591, 2017
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1CX9
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![BU of 1cx9 by Molmil](/molmil-images/mine/1cx9) | CRYSTAL STRUCTURE OF THE COMPLEX OF BACTERIAL TRYPTOPHAN SYNTHASE WITH THE TRANSITION STATE ANALOGUE INHIBITOR 4-(2-AMINOPHENYLTHIO)-BUTYLPHOSPHONIC ACID | Descriptor: | 4-(2-AMINOPHENYLTHIO)-BUTYLPHOSPHONIC ACID, PYRIDOXAL-5'-PHOSPHATE, SODIUM ION, ... | Authors: | Sachpatzidis, A, Dealwis, C, Lubetsky, J.B, Liang, P.H, Anderson, K.S, Lolis, E. | Deposit date: | 1999-08-29 | Release date: | 1999-12-29 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Crystallographic studies of phosphonate-based alpha-reaction transition-state analogues complexed to tryptophan synthase. Biochemistry, 38, 1999
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1D9E
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![BU of 1d9e by Molmil](/molmil-images/mine/1d9e) | STRUCTURE OF E. COLI KDO8P SYNTHASE | Descriptor: | 3-DEOXY-D-MANNO-OCTULOSONATE 8-PHOSPHATE SYNTHASE, SULFATE ION | Authors: | Radaev, S, Dastidar, P, Patel, M, Woodard, R.W, Gatti, D.L. | Deposit date: | 1999-10-27 | Release date: | 2000-05-10 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Structure and mechanism of 3-deoxy-D-manno-octulosonate 8-phosphate synthase. J.Biol.Chem., 275, 2000
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1CJX
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![BU of 1cjx by Molmil](/molmil-images/mine/1cjx) | CRYSTAL STRUCTURE OF PSEUDOMONAS FLUORESCENS HPPD | Descriptor: | 4-HYDROXYPHENYLPYRUVATE DIOXYGENASE, ACETATE ION, ETHYL MERCURY ION, ... | Authors: | Serre, L, Sailland, A, Sy, D, Boudec, P, Rolland, A, Pebay-Peroulla, E, Cohen-Addad, C. | Deposit date: | 1999-04-20 | Release date: | 2000-04-26 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Crystal structure of Pseudomonas fluorescens 4-hydroxyphenylpyruvate dioxygenase: an enzyme involved in the tyrosine degradation pathway. Structure Fold.Des., 7, 1999
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1CMX
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![BU of 1cmx by Molmil](/molmil-images/mine/1cmx) | |
2AXU
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![BU of 2axu by Molmil](/molmil-images/mine/2axu) | Structure of PrgX | Descriptor: | PrgX | Authors: | Shi, K, Brown, C.K, Gu, Z.Y, Kozlowicz, B.K, Dunny, G.M, Ohlendorf, D.H, Earhart, C.A. | Deposit date: | 2005-09-06 | Release date: | 2005-12-06 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Structure of peptide sex pheromone receptor PrgX and PrgX/pheromone complexes and regulation of conjugation in Enterococcus faecalis. Proc.Natl.Acad.Sci.Usa, 102, 2005
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7AOI
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![BU of 7aoi by Molmil](/molmil-images/mine/7aoi) | Trypanosoma brucei mitochondrial ribosome large subunit assembly intermediate | Descriptor: | 50S ribosomal protein L13, 50S ribosomal protein L14, 50S ribosomal protein L17, ... | Authors: | Tobiasson, V, Gahura, O, Aibara, S, Baradaran, R, Zikova, A, Amunts, A. | Deposit date: | 2020-10-14 | Release date: | 2020-12-02 | Last modified: | 2021-03-24 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Interconnected assembly factors regulate the biogenesis of mitoribosomal large subunit. Embo J., 40, 2021
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5OPH
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![BU of 5oph by Molmil](/molmil-images/mine/5oph) | |
1APZ
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![BU of 1apz by Molmil](/molmil-images/mine/1apz) | |
7CD0
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![BU of 7cd0 by Molmil](/molmil-images/mine/7cd0) | Crystal structure of the 2-iodoporphobilinogen-bound ES2 intermediate form of human hydroxymethylbilane synthase | Descriptor: | 3-[4-(2-hydroxy-2-oxoethyl)-5-[[4-(2-hydroxy-2-oxoethyl)-5-[[4-(2-hydroxy-2-oxoethyl)-5-[[4-(2-hydroxy-2-oxoethyl)-3-(3-hydroxy-3-oxopropyl)-5-methyl-1~{H}-pyrrol-2-yl]methyl]-3-(3-hydroxy-3-oxopropyl)-1~{H}-pyrrol-2-yl]methyl]-3-(3-hydroxy-3-oxopropyl)-1~{H}-pyrrol-2-yl]methyl]-1~{H}-pyrrol-3-yl]propanoic acid, 3-[5-(aminomethyl)-4-(carboxymethyl)-2-iodo-1H-pyrrol-3-yl]propanoic acid, Porphobilinogen deaminase | Authors: | Sato, H, Sugishima, M, Wada, K, Hirabayashi, K, Tsukaguchi, M. | Deposit date: | 2020-06-18 | Release date: | 2021-03-17 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.31 Å) | Cite: | Crystal structures of hydroxymethylbilane synthase complexed with a substrate analog: a single substrate-binding site for four consecutive condensation steps. Biochem.J., 478, 2021
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7CCZ
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![BU of 7ccz by Molmil](/molmil-images/mine/7ccz) | Crystal structure of the ES2 intermediate form of human hydroxymethylbilane synthase | Descriptor: | 3-[4-(2-hydroxy-2-oxoethyl)-5-[[4-(2-hydroxy-2-oxoethyl)-5-[[4-(2-hydroxy-2-oxoethyl)-5-[[4-(2-hydroxy-2-oxoethyl)-3-(3-hydroxy-3-oxopropyl)-5-methyl-1~{H}-pyrrol-2-yl]methyl]-3-(3-hydroxy-3-oxopropyl)-1~{H}-pyrrol-2-yl]methyl]-3-(3-hydroxy-3-oxopropyl)-1~{H}-pyrrol-2-yl]methyl]-1~{H}-pyrrol-3-yl]propanoic acid, Porphobilinogen deaminase | Authors: | Sato, H, Sugishima, M, Wada, K, Hirabayashi, K, Tsukaguchi, M. | Deposit date: | 2020-06-18 | Release date: | 2021-03-17 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.79 Å) | Cite: | Crystal structures of hydroxymethylbilane synthase complexed with a substrate analog: a single substrate-binding site for four consecutive condensation steps. Biochem.J., 478, 2021
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7CCX
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![BU of 7ccx by Molmil](/molmil-images/mine/7ccx) | Crystal structure of the holo form of human hydroxymethylbilane synthase | Descriptor: | 3-[5-{[3-(2-carboxyethyl)-4-(carboxymethyl)-5-methyl-1H-pyrrol-2-yl]methyl}-4-(carboxymethyl)-1H-pyrrol-3-yl]propanoic acid, Porphobilinogen deaminase | Authors: | Sato, H, Sugishima, M, Wada, K, Hirabayashi, K, Tsukaguchi, M. | Deposit date: | 2020-06-18 | Release date: | 2021-03-17 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.84 Å) | Cite: | Crystal structures of hydroxymethylbilane synthase complexed with a substrate analog: a single substrate-binding site for four consecutive condensation steps. Biochem.J., 478, 2021
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1ZZJ
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![BU of 1zzj by Molmil](/molmil-images/mine/1zzj) | Structure of the third KH domain of hnRNP K in complex with 15-mer ssDNA | Descriptor: | 5'-D(*TP*TP*CP*CP*CP*CP*TP*CP*CP*CP*CP*AP*TP*TP*T)-3', Heterogeneous nuclear ribonucleoprotein K | Authors: | Backe, P.H, Messias, A.C, Ravelli, R.B, Sattler, M, Cusack, S. | Deposit date: | 2005-06-14 | Release date: | 2005-08-09 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | X-Ray Crystallographic and NMR Studies of the Third KH Domain of hnRNP K in Complex with Single-Stranded Nucleic Acids STRUCTURE, 13, 2005
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7CCY
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![BU of 7ccy by Molmil](/molmil-images/mine/7ccy) | Crystal structure of the 2-iodoporphobilinogen-bound holo form of human hydroxymethylbilane synthase | Descriptor: | 3-[5-(aminomethyl)-4-(carboxymethyl)-2-iodo-1H-pyrrol-3-yl]propanoic acid, 3-[5-{[3-(2-carboxyethyl)-4-(carboxymethyl)-5-methyl-1H-pyrrol-2-yl]methyl}-4-(carboxymethyl)-1H-pyrrol-3-yl]propanoic acid, Porphobilinogen deaminase | Authors: | Sato, H, Sugishima, M, Wada, K, Hirabayashi, K, Tsukaguchi, M. | Deposit date: | 2020-06-18 | Release date: | 2021-03-17 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Crystal structures of hydroxymethylbilane synthase complexed with a substrate analog: a single substrate-binding site for four consecutive condensation steps. Biochem.J., 478, 2021
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6HOF
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![BU of 6hof by Molmil](/molmil-images/mine/6hof) | |
6RL2
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![BU of 6rl2 by Molmil](/molmil-images/mine/6rl2) | The crystal structure of AbnE, an arabino-oligosaccharide binding protein, in complex with arabinotetraose | Descriptor: | Arabino-oligosaccharids-binding protein, CALCIUM ION, GLYCEROL, ... | Authors: | Lansky, S, Salama, R, Shoham, Y, Shoham, G. | Deposit date: | 2019-05-01 | Release date: | 2020-04-15 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.94 Å) | Cite: | Carbohydrate-Binding Capability and Functional Conformational Changes of AbnE, an Arabino-oligosaccharide Binding Protein. J.Mol.Biol., 432, 2020
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5TGZ
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![BU of 5tgz by Molmil](/molmil-images/mine/5tgz) | Crystal Structure of the Human Cannabinoid Receptor CB1 | Descriptor: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, 4-[4-[2-(2,4-dichlorophenyl)-4-methyl-5-(piperidin-1-ylcarbamoyl)pyrazol-3-yl]phenyl]but-3-ynyl nitrate, Cannabinoid receptor 1,Flavodoxin,Cannabinoid receptor 1, ... | Authors: | Hua, T, Vemuri, K, Pu, M, Qu, L, Han, G.W, Wu, Y, Zhao, S, Shui, W, Li, S, Korde, A, Laprairie, R.B, Stahl, E.L, Ho, J.H, Zvonok, N, Zhou, H, Kufareva, I, Wu, B, Zhao, Q, Hanson, M.A, Bohn, L.M, Makriyannis, A, Stevens, R.C, Liu, Z.J. | Deposit date: | 2016-09-28 | Release date: | 2016-11-02 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Crystal Structure of the Human Cannabinoid Receptor CB1. Cell, 167, 2016
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2AWI
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![BU of 2awi by Molmil](/molmil-images/mine/2awi) | Structure of PrgX Y153C mutant | Descriptor: | PrgX | Authors: | Shi, K, Brown, C.K, Gu, Z.Y, Kozlowicz, B.k, Dunny, G.M, Ohlendorf, D.H, Earhart, C.A. | Deposit date: | 2005-09-01 | Release date: | 2005-12-06 | Last modified: | 2021-10-20 | Method: | X-RAY DIFFRACTION (2.25 Å) | Cite: | Structure of peptide sex pheromone receptor PrgX and PrgX/pheromone complexes and regulation of conjugation in Enterococcus faecalis. Proc.Natl.Acad.Sci.Usa, 102, 2005
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