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4YBN
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BU of 4ybn by Molmil
Structure of the FAD and Heme binding protein msmeg_4975 from Mycobacterium smegmatis
Descriptor: ACETATE ION, FLAVIN-ADENINE DINUCLEOTIDE, Flavin-nucleotide-binding protein, ...
Authors:Ahmed, F.H, Carr, P.D, Jackson, C.J.
Deposit date:2015-02-18
Release date:2015-10-21
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Sequence-Structure-Function Classification of a Catalytically Diverse Oxidoreductase Superfamily in Mycobacteria.
J.Mol.Biol., 427, 2015
3OUV
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BU of 3ouv by Molmil
SeMet Derivative of L512M mutant of PASTA domain 3 of Mycobacterium tuberculosis PknB
Descriptor: Serine/threonine protein kinase
Authors:Prigozhin, D.M, Chen, T.Y, Alber, T.
Deposit date:2010-09-15
Release date:2011-09-21
Last modified:2016-12-14
Method:X-RAY DIFFRACTION (2.004 Å)
Cite:Structural and Genetic Analyses of the Mycobacterium tuberculosis Protein Kinase B Sensor Domain Identify a Potential Ligand-binding Site.
J.Biol.Chem., 291, 2016
6AYU
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BU of 6ayu by Molmil
Crystal structure of fructose-1,6-bisphosphatase T84S from Mycobacterium tuberculosis
Descriptor: 6-O-phosphono-beta-D-fructofuranose, Fructose-1,6-bisphosphatase class 2, GLYCEROL, ...
Authors:Abad-Zapatero, C, Wolf, N, Gutka, H.J, Movahedzadeh, F.
Deposit date:2017-09-08
Release date:2018-03-14
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structures of the Mycobacterium tuberculosis GlpX protein (class II fructose-1,6-bisphosphatase): implications for the active oligomeric state, catalytic mechanism and citrate inhibition.
Acta Crystallogr D Struct Biol, 74, 2018
5DC2
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BU of 5dc2 by Molmil
X-RAY CRYSTAL STRUCTURE OF A ENZYMATICALLY DEGRADED BIAPENEM-ADDUCT OF L,D-TRANSPEPTIDASE 2 FROM MYCOBACTERIUM TUBERCULOSIS
Descriptor: (4S)-4-methyl-2,5,7-trioxoheptanoic acid, 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, ...
Authors:Pan, Y, Basta, L, Lamichhane, G, Bianchet, M.A.
Deposit date:2015-08-23
Release date:2016-10-05
Last modified:2019-12-11
Method:X-RAY DIFFRACTION (2.182 Å)
Cite:Structural insight into the inactivation of Mycobacterium tuberculosis non-classical transpeptidase LdtMt2 by biapenem and tebipenem.
BMC Biochem., 18, 2017
6DNM
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BU of 6dnm by Molmil
The crystal structure of SatS c-terminal domain
Descriptor: Export chaperone SatS
Authors:Hughes, R.C, Sacchettini, J.C, TB Structural Genomics Consortium (TBSGC)
Deposit date:2018-06-07
Release date:2019-01-23
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (1.397 Å)
Cite:Mycobacterium tuberculosisSatS is a chaperone for the SecA2 protein export pathway.
Elife, 8, 2019
5D5H
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BU of 5d5h by Molmil
Crystal structure of Mycobacterium tuberculosis Topoisomerase I
Descriptor: ACETATE ION, DNA topoisomerase 1, GLYCEROL, ...
Authors:Tan, K, Cheng, B, Tse-Dinh, Y.C.
Deposit date:2015-08-10
Release date:2015-12-16
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (2.52 Å)
Cite:Insights from the Structure of Mycobacterium tuberculosis Topoisomerase I with a Novel Protein Fold.
J.Mol.Biol., 428, 2016
5XD2
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BU of 5xd2 by Molmil
Crystal structure of Mycobacterium smegmatis MutT1 in complex with Ap5A, ATP and manganese
Descriptor: ADENOSINE-5'-PENTAPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, GLYCEROL, ...
Authors:Arif, S.M, Varshney, U, Vijayan, M.
Deposit date:2017-03-24
Release date:2017-08-09
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Hydrolysis of diadenosine polyphosphates. Exploration of an additional role of Mycobacterium smegmatis MutT1
J. Struct. Biol., 199, 2017
5E12
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BU of 5e12 by Molmil
Crystal Structure of PASTA Domains 2, 3 and 4 of Mycobacterium tuberculosis Protein Kinase B
Descriptor: CITRATE ANION, Serine/threonine-protein kinase PknB
Authors:Prigozhin, D.M, TB Structural Genomics Consortium (TBSGC)
Deposit date:2015-09-29
Release date:2016-09-14
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (2.208 Å)
Cite:Structural and Genetic Analyses of the Mycobacterium tuberculosis Protein Kinase B Sensor Domain Identify a Potential Ligand-binding Site.
J.Biol.Chem., 291, 2016
6DRQ
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BU of 6drq by Molmil
The crystal structure of SatS c-terminal domain in complex with bromine
Descriptor: BROMIDE ION, Primosomal protein
Authors:Hughes, R.C, Sacchettini, J.C, TB Structural Genomics Consortium (TBSGC)
Deposit date:2018-06-12
Release date:2019-01-23
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Mycobacterium tuberculosisSatS is a chaperone for the SecA2 protein export pathway.
Elife, 8, 2019
5E10
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BU of 5e10 by Molmil
Crystal Structure of PASTA Domains 1 and 2 of Mycobacterium tuberculosis Protein Kinase B
Descriptor: Serine/threonine-protein kinase PknB
Authors:Prigozhin, D.M, TB Structural Genomics Consortium (TBSGC)
Deposit date:2015-09-29
Release date:2016-09-14
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (1.801 Å)
Cite:Structural and Genetic Analyses of the Mycobacterium tuberculosis Protein Kinase B Sensor Domain Identify a Potential Ligand-binding Site.
J.Biol.Chem., 291, 2016
5E0Y
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BU of 5e0y by Molmil
Crystal Structure of PASTA Domain 4 of Mycobacterium tuberculosis Protein Kinase B
Descriptor: Serine/threonine-protein kinase PknB, ZINC ION
Authors:Prigozhin, D.M, TB Structural Genomics Consortium (TBSGC)
Deposit date:2015-09-29
Release date:2016-09-14
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (2.001 Å)
Cite:Structural and Genetic Analyses of the Mycobacterium tuberculosis Protein Kinase B Sensor Domain Identify a Potential Ligand-binding Site.
J.Biol.Chem., 291, 2016
5XD5
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BU of 5xd5 by Molmil
Crystal structure of Mycobacterium smegmatis MutT1 in complex with ATP, magnesium fluoride and phosphate
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, CHLORIDE ION, FLUORIDE ION, ...
Authors:Arif, S.M, Varshney, U, Vijayan, M.
Deposit date:2017-03-24
Release date:2017-08-09
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Hydrolysis of diadenosine polyphosphates. Exploration of an additional role of Mycobacterium smegmatis MutT1
J. Struct. Biol., 199, 2017
5XD4
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BU of 5xd4 by Molmil
Crystal structure of Mycobacterium smegmatis MutT1 in complex with ATP (II)
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, GLYCEROL, MAGNESIUM ION, ...
Authors:Arif, S.M, Varshney, U, Vijayan, M.
Deposit date:2017-03-24
Release date:2017-08-09
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.47 Å)
Cite:Hydrolysis of diadenosine polyphosphates. Exploration of an additional role of Mycobacterium smegmatis MutT1
J. Struct. Biol., 199, 2017
4X5C
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BU of 4x5c by Molmil
Anthranilate phosphoribosyltransferase variant R193L from Mycobacterium tuberculosis with pyrophosphate/PRPP and Mg2+ bound
Descriptor: 1-O-pyrophosphono-5-O-phosphono-alpha-D-ribofuranose, Anthranilate phosphoribosyltransferase, MAGNESIUM ION, ...
Authors:Cookson, T.V.M, Parker, E.J, Lott, J.S.
Deposit date:2014-12-05
Release date:2015-11-25
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.33 Å)
Cite:Structures of Mycobacterium tuberculosis Anthranilate Phosphoribosyltransferase Variants Reveal the Conformational Changes That Facilitate Delivery of the Substrate to the Active Site.
Biochemistry, 54, 2015
4X5B
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BU of 4x5b by Molmil
Anthranilate phosphoribosyltransferase variant R193L from Mycobacterium tuberculosis in complex with PRPP and Mg
Descriptor: 1-O-pyrophosphono-5-O-phosphono-alpha-D-ribofuranose, Anthranilate phosphoribosyltransferase, MAGNESIUM ION
Authors:Cookson, T.V.M, Parker, E.J, Lott, J.S.
Deposit date:2014-12-05
Release date:2015-11-18
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.47 Å)
Cite:Structures of Mycobacterium tuberculosis Anthranilate Phosphoribosyltransferase Variants Reveal the Conformational Changes That Facilitate Delivery of the Substrate to the Active Site.
Biochemistry, 54, 2015
4X5D
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BU of 4x5d by Molmil
Anthranilate phosphoribosyltransferase variant R193A from Mycobacterium tuberculosis with anthranilate bound
Descriptor: 2-AMINOBENZOIC ACID, Anthranilate phosphoribosyltransferase, GLYCEROL, ...
Authors:Cookson, T.V.M, Parker, E.J, Lott, J.S.
Deposit date:2014-12-05
Release date:2015-09-23
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structures of Mycobacterium tuberculosis Anthranilate Phosphoribosyltransferase Variants Reveal the Conformational Changes That Facilitate Delivery of the Substrate to the Active Site.
Biochemistry, 54, 2015
4UY6
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BU of 4uy6 by Molmil
Crystal structure of Histidine and SAH bound Histidine-specific methyltransferase EgtD from Mycobacterium smegmatis
Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, HISTIDINE, HISTIDINE-SPECIFIC METHYLTRANSFERASE EGTD, ...
Authors:Jeong, J.H, Kim, Y.G.
Deposit date:2014-08-29
Release date:2014-10-08
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.04 Å)
Cite:Structural Insights Into the Histidine Trimethylation Activity of Egtd from Mycobacterium Smegmatis.
Biochem.Biophys.Res.Commun., 452, 2014
4UAQ
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BU of 4uaq by Molmil
Crystal structure of the accessory translocation ATPase, SecA2, from Mycobacterium tuberculosis
Descriptor: Protein translocase subunit SecA 2
Authors:Swanson-Smith, S, Ioerger, T.R, Rigel, N.W, Miller, B.K, Braunstein, M, Sacchettini, J.C, TB Structural Genomics Consortium (TBSGC)
Deposit date:2014-08-11
Release date:2015-09-09
Last modified:2024-10-09
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural Similarities and Differences between Two Functionally Distinct SecA Proteins, Mycobacterium tuberculosis SecA1 and SecA2.
J.Bacteriol., 198, 2015
4XY3
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BU of 4xy3 by Molmil
Structure of ESX-1 secreted protein EspB
Descriptor: ESX-1 secretion-associated protein EspB
Authors:Wagner, J.M, Korotkov, K.V.
Deposit date:2015-02-01
Release date:2015-02-18
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (3.04 Å)
Cite:Structure of EspB, a secreted substrate of the ESX-1 secretion system of Mycobacterium tuberculosis.
J.Struct.Biol., 191, 2015
6H59
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BU of 6h59 by Molmil
Crystal structure of Mycobacterium tuberculosis phosphatidylinositol phosphate synthase (PgsA1) with CDP-DAG bound
Descriptor: (2S)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, CDP-diacylglycerol--inositol 3-phosphatidyltransferase, MAGNESIUM ION, ...
Authors:Grave, K, Hogbom, M.
Deposit date:2018-07-24
Release date:2019-05-15
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structure ofMycobacterium tuberculosisphosphatidylinositol phosphate synthase reveals mechanism of substrate binding and metal catalysis.
Commun Biol, 2, 2019
6A7V
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BU of 6a7v by Molmil
Crystal structure of Mycobacterium tuberculosis VapBC11 toxin-antitoxin complex
Descriptor: Antitoxin VapB11, PENTAETHYLENE GLYCOL, Ribonuclease VapC11, ...
Authors:Deep, A, Thakur, K.G.
Deposit date:2018-07-04
Release date:2018-10-10
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.67 Å)
Cite:Structural, functional and biological insights into the role of Mycobacterium tuberculosis VapBC11 toxin-antitoxin system: targeting a tRNase to tackle mycobacterial adaptation.
Nucleic Acids Res., 46, 2018
4XU4
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BU of 4xu4 by Molmil
Crystal structure of a mycobacterial Insig homolog MvINS from Mycobacterium vanbaalenii at 1.9A resolution
Descriptor: DECYLAMINE-N,N-DIMETHYL-N-OXIDE, Uncharacterized protein, nonyl beta-D-glucopyranoside
Authors:Ren, R.B, Wu, J.P, Yan, C.Y, He, Y, Yan, N.
Deposit date:2015-01-25
Release date:2015-10-14
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (1.901 Å)
Cite:PROTEIN STRUCTURE. Crystal structure of a mycobacterial Insig homolog provides insight into how these sensors monitor sterol levels
Science, 349, 2015
5WW6
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BU of 5ww6 by Molmil
Crystal structure of the second DNA-Binding protein under starvation from Mycobacterium smegmatis soaked with iron in the ratio of 240 iron atoms per dodecamer
Descriptor: CHLORIDE ION, FE (II) ION, FE (III) ION, ...
Authors:Williams, S.M, Chatterji, D.
Deposit date:2016-12-31
Release date:2017-08-09
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.04 Å)
Cite:Flexible aspartates propel iron to the ferroxidation sites along pathways stabilized by a conserved arginine in Dps proteins from Mycobacterium smegmatis
Metallomics, 9, 2017
5WW8
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BU of 5ww8 by Molmil
Crystal structure of the second DNA-Binding protein under starvation from Mycobacterium smegmatis soaked with iron in the ratio of 480 iron atoms per dodecamer
Descriptor: CHLORIDE ION, FE (II) ION, FE (III) ION, ...
Authors:Williams, S.M, Chatterji, D.
Deposit date:2016-12-31
Release date:2017-08-09
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.04 Å)
Cite:Flexible aspartates propel iron to the ferroxidation sites along pathways stabilized by a conserved arginine in Dps proteins from Mycobacterium smegmatis
Metallomics, 9, 2017
3O8G
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BU of 3o8g by Molmil
EthR from Mycobacterium tuberculosis in complex with compound BDM14801
Descriptor: 1-(azidoacetyl)-4-(3-thiophen-2-yl-1,2,4-oxadiazol-5-yl)piperidine, TRANSCRIPTIONAL REGULATORY REPRESSOR PROTEIN (TETR-FAMILY) ETHR
Authors:Willand, N, Desroses, M, Toto, P, Diri, B, Lens, Z, Villeret, V, Rucktooa, P, Locht, C, Baulard, A, Deprez, B.
Deposit date:2010-08-03
Release date:2010-09-01
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Exploring drug target flexibility using in situ click chemistry: application to a mycobacterial transcriptional regulator.
Acs Chem.Biol., 5, 2010

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