7Q87
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![BU of 7q87 by Molmil](/molmil-images/mine/7q87) | Carboxypeptidase T with (S)-3-phenyllactic acid | Descriptor: | ALPHA-HYDROXY-BETA-PHENYL-PROPIONIC ACID, CALCIUM ION, Carboxypeptidase T, ... | Authors: | Timofeev, V.I, Akparov, V.K, Shevtsov, M.B, Kuranova, I.P. | Deposit date: | 2021-11-10 | Release date: | 2022-01-26 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.73 Å) | Cite: | Carboxypeptidase T with (S)-3-phenyllactic acid To Be Published
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3F5X
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![BU of 3f5x by Molmil](/molmil-images/mine/3f5x) | CDK-2-Cyclin complex with indazole inhibitor 9 bound at its active site | Descriptor: | 4-{3-[7-(4-methylpiperazin-1-yl)-1H-benzimidazol-2-yl]-1H-indazol-6-yl}aniline, Cell division protein kinase 2, Cyclin-A2, ... | Authors: | Kiefer, J.R, Day, J.E, Caspers, N.L, Mathis, K.J, Kretzmer, K.K, Weinberg, R.A, Reitz, B.A, Stegeman, R.A, Trujillo, J.I, Huang, W, Thorarensen, A, Xing, L, Wrightstone, A, Christine, L, Compton, R, Li, X. | Deposit date: | 2008-11-04 | Release date: | 2009-02-03 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | 2-(6-Phenyl-1H-indazol-3-yl)-1H-benzo[d]imidazoles: Design and synthesis of a potent and isoform selective PKC-zeta inhibitor. Bioorg.Med.Chem.Lett., 19, 2009
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6P0U
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![BU of 6p0u by Molmil](/molmil-images/mine/6p0u) | Crystal structure of ternary DNA complex " FX(1-2)-2Xis" containing E. coli Fis and phage lambda Xis | Descriptor: | DNA (27-MER), FX1-2, DNA-binding protein Fis, ... | Authors: | Hancock, S.P, Cascio, D, Johnson, R.C. | Deposit date: | 2019-05-17 | Release date: | 2019-06-19 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (3.3 Å) | Cite: | Cooperative DNA binding by proteins through DNA shape complementarity. Nucleic Acids Res., 47, 2019
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3NRW
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![BU of 3nrw by Molmil](/molmil-images/mine/3nrw) | Crystal Structure of the N-terminal domain of Phage integrase/site-specific recombinase (tnp) from Haloarcula marismortui, Northeast Structural Genomics Consortium Target HmR208A | Descriptor: | Phage integrase/site-specific recombinase | Authors: | Forouhar, F, Su, M, Seetharaman, J, Mao, M, Xiao, R, Ciccosanti, C, Wang, D, Everett, J.K, Nair, R, Acton, T.B, Rost, B, Montelione, G.T, Tong, L, Hunt, J.F, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2010-06-30 | Release date: | 2010-08-25 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Northeast Structural Genomics Consortium Target HmR208A To be Published
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3NY4
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![BU of 3ny4 by Molmil](/molmil-images/mine/3ny4) | Crystal Structure of BlaC-K73A bound with Cefamandole | Descriptor: | (6R,7R)-7-{[(2R)-2-hydroxy-2-phenylacetyl]amino}-3-{[(1-methyl-1H-tetrazol-5-yl)sulfanyl]methyl}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, Beta-lactamase, PHOSPHATE ION | Authors: | Tremblay, L.W, Blanchard, J.S. | Deposit date: | 2010-07-14 | Release date: | 2010-11-24 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.22 Å) | Cite: | Structures of the Michaelis Complex (1.2 A) and the Covalent Acyl Intermediate (2.0 A) of Cefamandole Bound in the Active Sites of the Mycobacterium tuberculosis beta-Lactamase K73A and E166A Mutants. Biochemistry, 49, 2010
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3O18
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![BU of 3o18 by Molmil](/molmil-images/mine/3o18) | |
3O2H
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![BU of 3o2h by Molmil](/molmil-images/mine/3o2h) | E. coli ClpS in complex with a Leu N-end rule peptide | Descriptor: | ATP-dependent Clp protease adaptor protein ClpS, DNA protection during starvation protein | Authors: | Roman-Hernandez, G, Grant, R.A, Sauer, R.T, Baker, T.A, de Regt, A. | Deposit date: | 2010-07-22 | Release date: | 2011-12-14 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | The ClpS adaptor mediates staged delivery of N-end rule substrates to the AAA+ ClpAP protease. Mol.Cell, 43, 2011
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3O2O
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![BU of 3o2o by Molmil](/molmil-images/mine/3o2o) | Structure of E. coli ClpS ring complex | Descriptor: | ATP-dependent Clp protease adaptor protein ClpS | Authors: | Roman-Hernandez, G, Grant, R.A, Sauer, R.T, Baker, T.A, de Regt, A. | Deposit date: | 2010-07-22 | Release date: | 2011-12-14 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | The ClpS adaptor mediates staged delivery of N-end rule substrates to the AAA+ ClpAP protease. Mol.Cell, 43, 2011
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3O3W
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![BU of 3o3w by Molmil](/molmil-images/mine/3o3w) | Crystal Structure of BH2092 protein (residues 14-131) from Bacillus halodurans, Northeast Structural Genomics Consortium Target BhR228A | Descriptor: | BH2092 protein | Authors: | Forouhar, F, Neely, H, Seetharaman, J, Sahdev, S, Xiao, R, Ciccosanti, C, Lee, D, Everett, J.K, Nair, R, Acton, T.B, Rost, B, Montelione, G.T, Tong, L, Hunt, J.F, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2010-07-26 | Release date: | 2010-09-01 | Last modified: | 2019-07-17 | Method: | X-RAY DIFFRACTION (2.91 Å) | Cite: | Crystal Structure of BH2092 protein (residues 14-131) from Bacillus halodurans, Northeast Structural Genomics Consortium Target BhR228A To be Published
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3M8C
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![BU of 3m8c by Molmil](/molmil-images/mine/3m8c) | Crystal Structure of Ketosteroid Isomerase D99N from Pseudomonas Testosteroni (tKSI) with Equilenin Bound | Descriptor: | EQUILENIN, GLYCEROL, SULFATE ION, ... | Authors: | Gonzalez, A, Tsai, Y, Schwans, J, Sunden, F, Herschlag, D. | Deposit date: | 2010-03-17 | Release date: | 2010-04-14 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Crystal Structure of Ketosteroid Isomerase D99N from Pseudomonas Testosteroni (tKSI) with Equilenin Bound TO BE PUBLISHED
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6YGD
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![BU of 6ygd by Molmil](/molmil-images/mine/6ygd) | Crystal structure of the NatC complex bound to Gag peptide and CoA | Descriptor: | 1,2-ETHANEDIOL, CHLORIDE ION, COENZYME A, ... | Authors: | Grunwald, S, Hopf, L, Bock-Bierbaum, T, Lally, C.C, Spahn, C.M.T, Daumke, O. | Deposit date: | 2020-03-27 | Release date: | 2020-10-28 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2.752 Å) | Cite: | Divergent architecture of the heterotrimeric NatC complex explains N-terminal acetylation of cognate substrates. Nat Commun, 11, 2020
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3M9K
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![BU of 3m9k by Molmil](/molmil-images/mine/3m9k) | Crystal structure of human thioredoxin C69/73S double-mutant, oxidized form | Descriptor: | (4S,5S)-1,2-DITHIANE-4,5-DIOL, SULFATE ION, Thioredoxin | Authors: | Weichsel, A, Montfort, W.R. | Deposit date: | 2010-03-22 | Release date: | 2010-08-11 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Crystal structure of human thioredoxin revealing an unraveled helix and exposed S-nitrosation site. Protein Sci., 19, 2010
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7QGK
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![BU of 7qgk by Molmil](/molmil-images/mine/7qgk) | The mRubyFT protein, Genetically Encoded Blue-to-Red Fluorescent Timer in its red state | Descriptor: | MAGNESIUM ION, The red form of the mRubyFT protein, Genetically Encoded Blue-to-Red Fluorescent Timer | Authors: | Boyko, K.M, Nikolaeva, A.Y, Gaivoronskii, F.A, Vlaskina, A.V, Subach, O.M, Popov, V.O, Subach, F.V. | Deposit date: | 2021-12-08 | Release date: | 2022-03-23 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | The mRubyFT Protein, Genetically Encoded Blue-to-Red Fluorescent Timer. Int J Mol Sci, 23, 2022
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3EXI
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![BU of 3exi by Molmil](/molmil-images/mine/3exi) | Crystal structure of the pyruvate dehydrogenase (E1p) component of human pyruvate dehydrogenase complex with the subunit-binding domain (SBD) of E2p, but SBD cannot be modeled into the electron density | Descriptor: | CHLORIDE ION, POTASSIUM ION, Pyruvate dehydrogenase E1 component subunit alpha, ... | Authors: | Kato, M, Wynn, R.M, Chuang, J.L, Tso, S.-C, Machius, M, Li, J, Chuang, D.T. | Deposit date: | 2008-10-16 | Release date: | 2008-11-25 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Structural basis for inactivation of the human pyruvate dehydrogenase complex by phosphorylation: role of disordered phosphorylation loops. Structure, 16, 2008
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3M8M
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![BU of 3m8m by Molmil](/molmil-images/mine/3m8m) | 1.05 A Structure of Manganese-free Manganese Peroxidase | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, GLYCEROL, ... | Authors: | Sundaramoorthy, M, Gold, M.H, Poulos, T.L. | Deposit date: | 2010-03-18 | Release date: | 2010-04-14 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (1.05 Å) | Cite: | Ultrahigh (0.93A) resolution structure of manganese peroxidase from Phanerochaete chrysosporium: implications for the catalytic mechanism. J.Inorg.Biochem., 104, 2010
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6FAO
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![BU of 6fao by Molmil](/molmil-images/mine/6fao) | Discovery and characterization of a thermostable GH6 endoglucanase from a compost metagenome | Descriptor: | 1,2-ETHANEDIOL, Glycoside hydrolase family 6, SULFATE ION | Authors: | Jensen, M.S, Fredriksen, L, MacKenzie, A.K, Pope, P.B, Chylenski, P, Leiros, I, Williamson, A.K, Christopeit, T, Ostby, H, Vaaje-Kolstad, G, Eijsink, V.G.H. | Deposit date: | 2017-12-15 | Release date: | 2018-06-06 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (1.88 Å) | Cite: | Discovery and characterization of a thermostable two-domain GH6 endoglucanase from a compost metagenome. PLoS ONE, 13, 2018
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3EZV
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![BU of 3ezv by Molmil](/molmil-images/mine/3ezv) | CDK-2 with indazole inhibitor 9 bound at its active site | Descriptor: | 4-{3-[7-(4-methylpiperazin-1-yl)-1H-benzimidazol-2-yl]-1H-indazol-6-yl}aniline, Cell division protein kinase 2 | Authors: | Kiefer, J.R, Day, J.E, Caspers, N.L, Mathis, K.J, Kretzmer, K.K, Weinberg, R.A, Reitz, B.A, Stegeman, R.A, Trujillo, J.I, Huang, W, Thorarensen, A, Xing, L, Wrightstone, A, Christine, L, Compton, R, Li, X. | Deposit date: | 2008-10-23 | Release date: | 2009-02-03 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (1.99 Å) | Cite: | 2-(6-Phenyl-1H-indazol-3-yl)-1H-benzo[d]imidazoles: Design and synthesis of a potent and isoform selective PKC-zeta inhibitor Bioorg.Med.Chem.Lett., 19, 2009
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3MEP
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![BU of 3mep by Molmil](/molmil-images/mine/3mep) | Crystal Structure of ECA2234 protein from Erwinia carotovora, Northeast Structural Genomics Consortium Target EwR44 | Descriptor: | uncharacterized protein ECA2234 | Authors: | Seetharaman, J, Abashidze, M, Forouhar, F, Mao, M, Xiao, R, Ciccosanti, C, Wang, D, Everett, J.K, Nair, R, Acton, T.B, Rost, B, Montelione, G.T, Tong, L, Hunt, J.F, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2010-03-31 | Release date: | 2010-04-14 | Last modified: | 2019-07-17 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Northeast Structural Genomics Consortium Target EwR44 To be Published
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3F1I
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![BU of 3f1i by Molmil](/molmil-images/mine/3f1i) | Human ESCRT-0 Core Complex | Descriptor: | Hepatocyte growth factor-regulated tyrosine kinase substrate, Signal transducing adapter molecule 1 | Authors: | Ren, X, Kloer, D.P, Kim, Y, Ghirlando, R, Saidi, L, Hummer, G, Hurley, J.H. | Deposit date: | 2008-10-28 | Release date: | 2009-03-24 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Hybrid Structural Model of the Complete Human ESCRT-0 Complex. Structure, 17, 2009
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3F1Y
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![BU of 3f1y by Molmil](/molmil-images/mine/3f1y) | Mannosyl-3-phosphoglycerate synthase from Rubrobacter xylanophilus | Descriptor: | CHLORIDE ION, MAGNESIUM ION, Mannosyl-3-phosphoglycerate synthase | Authors: | Macedo-Ribeiro, S, Pereira, P.J.B, Empadinhas, N, da Costa, M.S. | Deposit date: | 2008-10-28 | Release date: | 2009-11-03 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Functional and structural characterization of a novel mannosyl-3-phosphoglycerate synthase from Rubrobacter xylanophilus reveals its dual substrate specificity Mol.Microbiol., 79, 2011
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3MI3
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![BU of 3mi3 by Molmil](/molmil-images/mine/3mi3) | Homocitrate Synthase Lys4 bound to Lysine | Descriptor: | Homocitrate synthase, mitochondrial, LYSINE, ... | Authors: | Bulfer, S.L, Scott, E.M, Pillus, L, Trievel, R.C. | Deposit date: | 2010-04-09 | Release date: | 2010-04-28 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.38 Å) | Cite: | Structural Basis for L-lysine Feedback Inhibition of Homocitrate Synthase J.Biol.Chem., 285, 2010
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6Y0J
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3MJA
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![BU of 3mja by Molmil](/molmil-images/mine/3mja) | Cricket Paralysis Virus IGR IRES Domain 3 RNA bound to selenate, structure #2 | Descriptor: | Domain 3 of the cricket paralysis virus intergenic region IRES RNA, RNA (5'-R(P*UP*AP*AP*GP*AP*AP*AP*UP*UP*UP*AP*CP*CP*U)-3'), SELENATE ION | Authors: | Kieft, J.S, Golden, B.L, Costantino, D.A, Chase, E. | Deposit date: | 2010-04-12 | Release date: | 2010-05-19 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Identification and characterization of anion binding sites in RNA. Rna, 16, 2010
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3MFX
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![BU of 3mfx by Molmil](/molmil-images/mine/3mfx) | Crystal Structure of the sensory box domain of the sensory-box/GGDEF protein SO_1695 from Shewanella oneidensis, Northeast Structural Genomics Consortium Target SoR288B | Descriptor: | Sensory box/GGDEF family protein | Authors: | Forouhar, F, Abashidze, M, Seetharaman, J, Mao, M, Xiao, R, Ciccosanti, C, Lee, D, Everett, J.K, Nair, R, Acton, T.B, Rost, B, Montelione, G.T, Tong, L, Hunt, J.F, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2010-04-04 | Release date: | 2010-04-14 | Last modified: | 2019-07-17 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Northeast Structural Genomics Consortium Target SoR288B To be Published
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6PBH
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![BU of 6pbh by Molmil](/molmil-images/mine/6pbh) | |