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3UPT
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BU of 3upt by Molmil
Crystal structure of a transketolase from Burkholderia pseudomallei bound to TPP, calcium and ribose-5-phosphate
Descriptor: 5-O-phosphono-beta-D-ribofuranose, BROMIDE ION, CALCIUM ION, ...
Authors:Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2011-11-18
Release date:2011-12-14
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Combining functional and structural genomics to sample the essential Burkholderia structome.
Plos One, 8, 2013
4FS4
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BU of 4fs4 by Molmil
Structure of BACE Bound to (S)-4-(3'-methoxy-[1,1'-biphenyl]-3-yl)-1,4-dimethyl-6-oxotetrahydropyrimidin-2(1H)-iminium
Descriptor: (6S)-2-amino-6-(3'-methoxybiphenyl-3-yl)-3,6-dimethyl-5,6-dihydropyrimidin-4(3H)-one, Beta-secretase 1, L(+)-TARTARIC ACID
Authors:Strickland, C, Stamford, A.
Deposit date:2012-06-26
Release date:2012-10-10
Last modified:2014-07-23
Method:X-RAY DIFFRACTION (1.74 Å)
Cite:A Potent and Orally Efficacious, Hydroxyethylamine-Based Inhibitor of beta-Secretase.
ACS Med Chem Lett, 3, 2012
3U2U
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BU of 3u2u by Molmil
Crystal Structure of Human Glycogenin-1 (GYG1) complexed with manganese, UDP and maltotetraose
Descriptor: GLYCEROL, Glycogenin-1, MANGANESE (II) ION, ...
Authors:Chaikuad, A, Froese, D.S, Krysztofinska, E, von Delft, F, Weigelt, J, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Oppermann, U, Yue, W.W, Structural Genomics Consortium (SGC)
Deposit date:2011-10-04
Release date:2011-11-02
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:Conformational plasticity of glycogenin and its maltosaccharide substrate during glycogen biogenesis.
Proc.Natl.Acad.Sci.USA, 108, 2011
4GIL
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BU of 4gil by Molmil
Crystal Structure of Pseudouridine Monophosphate Glycosidase/Linear Pseudouridine 5'-Phosphate Adduct
Descriptor: MANGANESE (II) ION, Pseudouridine-5'-phosphate glycosidase, pseudouridine 5'-phosphate, ...
Authors:Huang, S, Mahanta, N, Begley, T.P, Ealick, S.E.
Deposit date:2012-08-08
Release date:2012-10-31
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.539 Å)
Cite:Pseudouridine monophosphate glycosidase: a new glycosidase mechanism.
Biochemistry, 51, 2012
4G6G
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BU of 4g6g by Molmil
Crystal structure of NDH with TRT
Descriptor: FLAVIN-ADENINE DINUCLEOTIDE, FRAGMENT OF TRITON X-100, MAGNESIUM ION, ...
Authors:Li, W, Feng, Y, Ge, J, Yang, M.
Deposit date:2012-07-19
Release date:2012-10-24
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.39 Å)
Cite:Structural insight into the type-II mitochondrial NADH dehydrogenases.
Nature, 491, 2012
3VLW
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BU of 3vlw by Molmil
Crystal structure of Sphingomonas sp. A1 alginate-binding protein AlgQ1 in complex with mannuronate-guluronate disaccharide
Descriptor: AlgQ1, CALCIUM ION, GLYCEROL, ...
Authors:Nishitani, Y, Maruyama, Y, Itoh, T, Mikami, B, Hashimoto, W, Murata, K.
Deposit date:2011-12-05
Release date:2012-01-25
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2 Å)
Cite:Recognition of heteropolysaccharide alginate by periplasmic solute-binding proteins of a bacterial ABC transporter
Biochemistry, 51, 2012
3MS7
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BU of 3ms7 by Molmil
Glycogen phosphorylase complexed with 2-chlorobenzaldehyde-4-(2,3,4,6-tetra-O-acetyl-beta-D-glucopyranosyl) thiosemicarbazone
Descriptor: Glycogen phosphorylase, muscle form, N-({(2E)-2-[(2-chlorophenyl)methylidene]hydrazino}carbonothioyl)-beta-D-glucopyranosylamine
Authors:Alexacou, K.-M.
Deposit date:2010-04-29
Release date:2011-01-05
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:The binding of beta-D-glucopyranosyl-thiosemicarbazone derivatives to glycogen phosphorylase: a new class of inhibitors
Bioorg.Med.Chem., 18, 2010
2MJW
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BU of 2mjw by Molmil
Structural Insights into Calcium Bound S100P - V Domain of the receptor for advanced glycation end products (RAGE) Complex
Descriptor: Advanced glycosylation end product-specific receptor, Protein S100-P
Authors:Rao, P.S.
Deposit date:2014-01-19
Release date:2014-11-05
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Structural insights into calcium-bound S100P and the V domain of the RAGE complex.
Plos One, 9, 2014
3E86
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BU of 3e86 by Molmil
High resolution Crystal Structure of the open NaK channel pore
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, CALCIUM ION, CESIUM ION, ...
Authors:Jiang, Y, Alam, A.
Deposit date:2008-08-19
Release date:2008-12-23
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:High-resolution structure of the open NaK channel
Nat.Struct.Mol.Biol., 16, 2009
2SCU
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BU of 2scu by Molmil
A detailed description of the structure of Succinyl-COA synthetase from Escherichia coli
Descriptor: COENZYME A, PROTEIN (SUCCINYL-COA LIGASE), SULFATE ION
Authors:Fraser, M.E, Wolodko, W.T, James, M.N.G, Bridger, W.A.
Deposit date:1998-09-24
Release date:1999-08-02
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:A detailed structural description of Escherichia coli succinyl-CoA synthetase.
J.Mol.Biol., 285, 1999
2YVE
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BU of 2yve by Molmil
Crystal structure of the methylene blue-bound form of the multi-drug binding transcriptional repressor CgmR
Descriptor: 3,7-BIS(DIMETHYLAMINO)PHENOTHIAZIN-5-IUM, CHLORIDE ION, GLYCEROL, ...
Authors:Itou, H, Shirakihara, Y, Tanaka, I.
Deposit date:2007-04-12
Release date:2008-04-15
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Crystal Structures of the Multidrug Binding Repressor Corynebacteriumglutamicum CgmR in Complex with Inducers and with an Operator
J.Mol.Biol., 403, 2010
6EOU
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BU of 6eou by Molmil
O-GlcNAc transferase TPR domain with the intellectual disability associated mutation L254F
Descriptor: UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit
Authors:Gundogdu, M, van Aalten, D.M.F.
Deposit date:2017-10-10
Release date:2018-05-09
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:The O-GlcNAc Transferase Intellectual Disability Mutation L254F Distorts the TPR Helix.
Cell Chem Biol, 25, 2018
6O83
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BU of 6o83 by Molmil
S. pombe ubiquitin E1~ubiquitin-AMP tetrahedral intermediate mimic
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 5'-{[(3-aminopropyl)sulfonyl]amino}-5'-deoxyadenosine, ...
Authors:Hann, Z.S, Lima, C.D.
Deposit date:2019-03-08
Release date:2019-06-19
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (3.153 Å)
Cite:Structural basis for adenylation and thioester bond formation in the ubiquitin E1.
Proc.Natl.Acad.Sci.USA, 116, 2019
2YVH
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BU of 2yvh by Molmil
Crystal structure of the operator-binding form of the multi-drug binding transcriptional repressor CgmR
Descriptor: 5'-D(*DGP*DGP*DTP*DCP*DGP*DGP*DTP*DAP*DCP*DAP*DGP*DTP*DTP*DA)-3', 5'-D(*DTP*DAP*DAP*DCP*DTP*DGP*DTP*DAP*DCP*DCP*DGP*DAP*DCP*DC)-3', Transcriptional regulator
Authors:Itou, H, Shirakihara, Y, Tanaka, I.
Deposit date:2007-04-12
Release date:2008-04-15
Last modified:2017-01-11
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal Structures of the Multidrug Binding Repressor Corynebacteriumglutamicum CgmR in Complex with Inducers and with an Operator
J.Mol.Biol., 403, 2010
5LMC
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BU of 5lmc by Molmil
Oxidized flavodiiron core of Escherichia coli flavorubredoxin, including the Fe-4SG atoms from its rubredoxin domain
Descriptor: ACETIC ACID, Anaerobic nitric oxide reductase flavorubredoxin, CACODYLATE ION, ...
Authors:Romao, C.V, Borges, P.T, Vicente, J.B, Carrondo, M.A, Teixeira, M, Frazao, C.
Deposit date:2016-07-29
Release date:2016-10-19
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structure of Escherichia coli Flavodiiron Nitric Oxide Reductase.
J.Mol.Biol., 428, 2016
8SJD
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BU of 8sjd by Molmil
Cryo-EM structure of the Hermes transposase bound to two right-ends of its DNA transposon.
Descriptor: DNA (46-MER), DNA (55-MER), DNA (8-MER), ...
Authors:Lannes, L, Dyda, F.
Deposit date:2023-04-17
Release date:2023-08-02
Last modified:2024-06-19
Method:ELECTRON MICROSCOPY (5.1 Å)
Cite:Zinc-finger BED domains drive the formation of the active Hermes transpososome by asymmetric DNA binding.
Nat Commun, 14, 2023
8DDW
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BU of 8ddw by Molmil
cryo-EM structure of TRPM3 ion channel in complex with Gbg, tethered by ALFA-nanobody
Descriptor: Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Transient receptor potential cation channel, ...
Authors:Zhao, C, MacKinnon, R.
Deposit date:2022-06-19
Release date:2022-11-02
Last modified:2024-06-12
Method:ELECTRON MICROSCOPY (4.7 Å)
Cite:Structural and functional analyses of a GPCR-inhibited ion channel TRPM3.
Neuron, 111, 2023
3NZQ
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BU of 3nzq by Molmil
Crystal Structure of Biosynthetic arginine decarboxylase ADC (SpeA) from Escherichia coli, Northeast Structural Genomics Consortium Target ER600
Descriptor: Biosynthetic arginine decarboxylase, SULFATE ION
Authors:Forouhar, F, Lew, S, Seetharaman, J, Sahdev, S, Xiao, R, Ciccosanti, C, Belote, R.L, Everett, J.K, Nair, R, Acton, T.B, Rost, B, Montelione, G.T, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG)
Deposit date:2010-07-16
Release date:2010-09-01
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Structures of bacterial biosynthetic arginine decarboxylases.
Acta Crystallogr.,Sect.F, 66, 2010
2WL6
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BU of 2wl6 by Molmil
BIOSYNTHETIC THIOLASE FROM Z. RAMIGERA. THE N316H-H348N MUTANT.
Descriptor: ACETYL-COA ACETYLTRANSFERASE
Authors:Merilainen, G, Poikela, V, Kursula, P, Wierenga, R.K.
Deposit date:2009-06-22
Release date:2009-11-03
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.98 Å)
Cite:The Thiolase Reaction Mechanism: The Importance of Asn316 and His348 for Stabilizing the Enolate Intermediate of the Claisen Condensation.
Biochemistry, 48, 2009
5M33
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BU of 5m33 by Molmil
Structural tuning of CD81LEL (space group P21)
Descriptor: 1,2-ETHANEDIOL, CD81 antigen
Authors:Cunha, E.S, Sfriso, P, Rojas, A.L, Roversi, P, Hospital, A, Orozco, M, Abrescia, N.G.
Deposit date:2016-10-14
Release date:2016-12-14
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.28 Å)
Cite:Mechanism of Structural Tuning of the Hepatitis C Virus Human Cellular Receptor CD81 Large Extracellular Loop.
Structure, 25, 2017
8DDX
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BU of 8ddx by Molmil
cryo-EM structure of TRPM3 ion channel in complex with Gbg in the presence of PIP2, tethered by ALFA-nanobody
Descriptor: (3beta,14beta,17beta,25R)-3-[4-methoxy-3-(methoxymethyl)butoxy]spirost-5-en, 1,2-DIACYL-GLYCEROL-3-SN-PHOSPHATE, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ...
Authors:Zhao, C, MacKinnon, R.
Deposit date:2022-06-19
Release date:2022-11-02
Last modified:2024-06-12
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Structural and functional analyses of a GPCR-inhibited ion channel TRPM3.
Neuron, 111, 2023
2ZAB
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BU of 2zab by Molmil
Crystal Structure of Family 7 Alginate Lyase A1-II' Y284F in Cmplex with Product (GGG)
Descriptor: Alginate lyase, GLYCEROL, alpha-L-gulopyranuronic acid-(1-4)-alpha-L-gulopyranuronic acid-(1-4)-alpha-L-gulopyranuronic acid
Authors:Ogura, K, Yamasaki, M, Mikami, B, Hashimoto, W, Murata, K.
Deposit date:2007-10-02
Release date:2008-05-27
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.66 Å)
Cite:Substrate Recognition in Tunnel of Family 7 Alginate Lyase from Sphingomonas sp. A1
To be Published
5M2C
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BU of 5m2c by Molmil
Structural tuning of CD81LEL (space group P32 1 2)
Descriptor: CD81 antigen, PHOSPHATE ION
Authors:Cunha, E.S, Sfriso, P, Rojas, A.L, Roversi, P, Hospital, A, Orozco, M, Abrescia, N.G.
Deposit date:2016-10-12
Release date:2016-12-14
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.961 Å)
Cite:Mechanism of Structural Tuning of the Hepatitis C Virus Human Cellular Receptor CD81 Large Extracellular Loop.
Structure, 25, 2017
8G6W
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BU of 8g6w by Molmil
Structure of WT E.coli 70S ribosome complexed with mRNA, P-site fMet-NH-tRNAfMet and A-site ortho-aminobenzoic acid charged NH-tRNAPhe
Descriptor: 16S rRNA, 2-AMINO-BENZAMIDE, 23S rRNA, ...
Authors:Majumdar, C, Cate, J.H.D.
Deposit date:2023-02-16
Release date:2023-04-05
Last modified:2023-11-15
Method:ELECTRON MICROSCOPY (2.02 Å)
Cite:Aminobenzoic Acid Derivatives Obstruct Induced Fit in the Catalytic Center of the Ribosome.
Acs Cent.Sci., 9, 2023
8G6X
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BU of 8g6x by Molmil
Structure of WT E.coli ribosome 50S subunit with complexed with mRNA, P-site fMet-NH-tRNAfMet and A-site meta-aminobenzoic acid charged NH-tRNAPhe
Descriptor: 23S rRNA, 3'-amino-3'-deoxyadenosine 5'-(dihydrogen phosphate), 3-aminobenzamide, ...
Authors:Majumdar, C, Cate, J.H.D.
Deposit date:2023-02-16
Release date:2023-03-22
Last modified:2023-11-15
Method:ELECTRON MICROSCOPY (2.31 Å)
Cite:Aminobenzoic Acid Derivatives Obstruct Induced Fit in the Catalytic Center of the Ribosome.
Acs Cent.Sci., 9, 2023

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