2C0T
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![BU of 2c0t by Molmil](/molmil-images/mine/2c0t) | Src family kinase Hck with bound inhibitor A-641359 | Descriptor: | CALCIUM ION, N-(4-{4-AMINO-1-[1-(TETRAHYDRO-2H-PYRAN-4-YL)PIPERIDIN-4-YL]-1H-PYRAZOLO[3,4-D]PYRIMIDIN-3-YL}-2-METHOXYPHENYL)-1-METHYL-1H-INDOLE-2-CARBOXAMIDE, TYROSINE-PROTEIN KINASE HCK | Authors: | Borhani, D.W, Burchat, A, Calderwood, D.J, Hirst, G.C, Li, B, Loew, A. | Deposit date: | 2005-09-07 | Release date: | 2006-09-20 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | Discovery of A-770041, a Src-Family Selective Orally Active Lck Inhibitor that Prevents Organ Allograft Rejection. Bioorg.Med.Chem.Lett., 16, 2006
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5AOV
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2C0O
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![BU of 2c0o by Molmil](/molmil-images/mine/2c0o) | Src family kinase Hck with bound inhibitor A-770041 | Descriptor: | CALCIUM ION, N-(4-{1-[4-(4-ACETYLPIPERAZIN-1-YL)-TRANS-CYCLOHEXYL]-4-AMINO-1H-PYRAZOLO[3,4-D]PYRIMIDIN-3-YL}-2-METHOXYPHENYL)-1-METHYL-1H-INDOLE-2-CARBOXAMIDE, TYROSINE-PROTEIN KINASE HCK | Authors: | Borhani, D.W, Burchat, A, Calderwood, D.J, Hirst, G.C, Li, B, Loew, A. | Deposit date: | 2005-09-06 | Release date: | 2006-09-20 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.85 Å) | Cite: | Discovery of A-770041, a Src-Family Selective Orally Active Lck Inhibitor that Prevents Organ Allograft Rejection. Bioorg.Med.Chem.Lett., 16, 2006
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2C0I
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![BU of 2c0i by Molmil](/molmil-images/mine/2c0i) | Src family kinase Hck with bound inhibitor A-420983 | Descriptor: | CALCIUM ION, N-(4-{4-AMINO-1-[4-(4-METHYLPIPERAZIN-1-YL)-TRANS-CYCLOHEXYL]-1H-PYRAZOLO[3,4-D]PYRIMIDIN-3-YL}-2-METHOXYPHENYL)-1-METHYL-1H-INDOLE-2-CARBOXAMIDE, TYROSINE-PROTEIN KINASE HCK | Authors: | Borhani, D.W, Burchat, A, Calderwood, D.J, Hirst, G.C, Li, B, Loew, A. | Deposit date: | 2005-09-03 | Release date: | 2006-09-20 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Discovery of A-770041, a Src-Family Selective Orally Active Lck Inhibitor that Prevents Organ Allograft Rejection. Bioorg.Med.Chem.Lett., 16, 2006
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2CWR
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![BU of 2cwr by Molmil](/molmil-images/mine/2cwr) | |
2BG9
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![BU of 2bg9 by Molmil](/molmil-images/mine/2bg9) | |
2KR6
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![BU of 2kr6 by Molmil](/molmil-images/mine/2kr6) | |
2KVD
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2KW1
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![BU of 2kw1 by Molmil](/molmil-images/mine/2kw1) | Solution structure of CTD | Descriptor: | Fas apoptotic inhibitory molecule 1 | Authors: | Ma, S, Zheng, X, Jin, C. | Deposit date: | 2010-03-30 | Release date: | 2011-04-13 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | Solution structure of CTD To be Published
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2KVX
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![BU of 2kvx by Molmil](/molmil-images/mine/2kvx) | Solution structure of kalata B12 | Descriptor: | Kalata-B12 | Authors: | Wang, C.K. | Deposit date: | 2010-03-29 | Release date: | 2011-03-09 | Last modified: | 2016-06-01 | Method: | SOLUTION NMR | Cite: | The role of conserved Glu residue on cyclotide stability and activity: a structural and functional study of kalata B12, a naturally occurring Glu to Asp mutant. Biochemistry, 50, 2011
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2KXR
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![BU of 2kxr by Molmil](/molmil-images/mine/2kxr) | ZO1 ZU5 domain MC/AA mutation | Descriptor: | Tight junction protein ZO-1 | Authors: | Wen, W, Zhang, M. | Deposit date: | 2010-05-12 | Release date: | 2011-03-30 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | Cdc42-dependent formation of the ZO-1/MRCKb complex at the leading edge controls cell migration Embo J., 30, 2011
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2KUB
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![BU of 2kub by Molmil](/molmil-images/mine/2kub) | Solution structure of the alpha subdomain of the major non-repeat unit of Fap1 fimbriae of Streptococcus parasanguis | Descriptor: | Fimbriae-associated protein Fap1 | Authors: | Ramboarina, S, Garnett, J.A, Bodey, A, Simpson, P, Bardiaux, B, Nilges, M, Matthews, S. | Deposit date: | 2010-02-17 | Release date: | 2010-07-21 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | Structural insights into serine-rich fimbriae from gram-positive bacteria. J.Biol.Chem., 2010
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2KV0
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![BU of 2kv0 by Molmil](/molmil-images/mine/2kv0) | 2-Aminopurine incorporation perturbs the dynamics and structure of DNA | Descriptor: | DNA (5'-D(*CP*GP*AP*CP*GP*TP*TP*TP*GP*CP*AP*GP*C)-3'), DNA (5'-D(*GP*CP*TP*GP*CP*AP*(2PR)P*AP*CP*GP*TP*CP*G)-3') | Authors: | Dallmann, A, Dehmel, L, Peters, T, Muegge, C, Griesinger, C.P, Tuma, J, Ernsting, N.P. | Deposit date: | 2010-03-03 | Release date: | 2011-01-19 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | 2-Aminopurine incorporation perturbs the dynamics and structure of DNA. Angew.Chem.Int.Ed.Engl., 49, 2010
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2KYU
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![BU of 2kyu by Molmil](/molmil-images/mine/2kyu) | The solution structure of the PHD3 finger of MLL | Descriptor: | Histone-lysine N-methyltransferase MLL, ZINC ION | Authors: | Park, S, Bushweller, J.H. | Deposit date: | 2010-06-08 | Release date: | 2010-08-25 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | The PHD3 domain of MLL acts as a CYP33-regulated switch between MLL-mediated activation and repression. Biochemistry, 49, 2010
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2KUA
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2KV6
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![BU of 2kv6 by Molmil](/molmil-images/mine/2kv6) | Tetrapeptide KWKK conjugated to oligonucleotide duplex by a trimethylene tether | Descriptor: | 5'-D(*GP*CP*TP*AP*GP*CP*GP*AP*GP*TP*CP*C)-3', 5'-D(*GP*GP*AP*CP*TP*CP*GP*CP*TP*AP*GP*C)-3', KWKK Tetrapeptide | Authors: | Huang, H, Kozekov, I.D, Kozekova, A, Rizzo, C.J, McCullough, A, LLoyd, R.S, Stone, M.P. | Deposit date: | 2010-03-08 | Release date: | 2010-07-21 | Last modified: | 2011-07-13 | Method: | SOLUTION NMR | Cite: | Minor Groove Orientation of the KWKK Peptide Tethered via the N-Terminal Amine to the Acrolein-Derived 1,N(2)-gamma-Hydroxypropanodeoxyguanosine Lesion with a Trimethylene Linkage . Biochemistry, 49, 2010
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2KYK
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![BU of 2kyk by Molmil](/molmil-images/mine/2kyk) | The sandwich region between two LMP2A PY motif regulates the interaction between AIP4WW2domain and PY motif | Descriptor: | E3 ubiquitin-protein ligase Itchy homolog | Authors: | Seo, M, Park, S, Seok, S, Kim, J, Cha, M, Lee, B. | Deposit date: | 2010-05-28 | Release date: | 2011-06-01 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | The sandwich region between two LMP2A PY motif regulates the interaction between AIP4WW2domain and PY motif To be Published
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2KT0
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2KYC
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2K7N
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2KLL
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![BU of 2kll by Molmil](/molmil-images/mine/2kll) | Solution structure of human interleukin-33 | Descriptor: | Interleukin-33 | Authors: | Lingel, A, Fairbrother, W. | Deposit date: | 2009-07-06 | Release date: | 2009-11-17 | Last modified: | 2024-05-08 | Method: | SOLUTION NMR | Cite: | Structure of IL-33 and its interaction with the ST2 and IL-1RAcP receptors--insight into heterotrimeric IL-1 signaling complexes. Structure, 17, 2009
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2L3Y
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![BU of 2l3y by Molmil](/molmil-images/mine/2l3y) | Solution structure of mouse IL-6 | Descriptor: | Interleukin-6 | Authors: | Veverka, V, Redpath, N.T, Carrington, B, Muskett, F.W, Taylor, R.J, Henry, A.J, Carr, M.D. | Deposit date: | 2010-09-25 | Release date: | 2011-09-28 | Last modified: | 2013-01-02 | Method: | SOLUTION NMR | Cite: | Conservation of functional sites on interleukin-6 and implications for evolution of signaling complex assembly and therapeutic intervention. J.Biol.Chem., 287, 2012
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2L5J
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![BU of 2l5j by Molmil](/molmil-images/mine/2l5j) | structure of the spliceosomal phosphopeptide P140 (phosphorylated form) | Descriptor: | U1 small nuclear ribonucleoprotein 70 kDa | Authors: | Quinternet, M, Page, N, Schall, N, Strub, J, Chaloin, O, Decossas, M, Cung, M, van Dorsselaer, A, Briand, J, Muller, S. | Deposit date: | 2010-11-02 | Release date: | 2010-12-01 | Last modified: | 2011-07-13 | Method: | SOLUTION NMR | Cite: | The spliceosomal phosphopeptide P140 controls the lupus disease by interacting with the HSC70 protein and via a mechanism mediated by gammadelta T cells. Plos One, 4, 2009
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2L3T
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![BU of 2l3t by Molmil](/molmil-images/mine/2l3t) | Solution structure of tandem SH2 domain from Spt6 | Descriptor: | Transcription elongation factor SPT6 | Authors: | Liu, J, Zhang, J, Wu, J, Shi, Y. | Deposit date: | 2010-09-22 | Release date: | 2011-06-15 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | Solution structure of the tandem SH2 domains from Spt6 and their binding to the phosphorylated RNA polymerase II C-terminal domain To be Published
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2LBZ
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![BU of 2lbz by Molmil](/molmil-images/mine/2lbz) | Thurincin H | Descriptor: | Thuricin17 | Authors: | Sit, C.S, van Belkum, M.J, Mckay, R.T, Worobo, R.W, Vederas, J.C. | Deposit date: | 2011-04-10 | Release date: | 2012-01-18 | Last modified: | 2018-08-22 | Method: | SOLUTION NMR | Cite: | The 3D solution structure of thurincin H, a bacteriocin with four sulfur to alpha-carbon crosslinks. Angew.Chem.Int.Ed.Engl., 50, 2011
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