2KVD
Mesencephalic astrocyte-derived neurotrophic factor (MANF)
Summary for 2KVD
| Entry DOI | 10.2210/pdb2kvd/pdb |
| Related | 2KVE |
| NMR Information | BMRB: 16775 |
| Descriptor | Mesencephalic astrocyte-derived neurotrophic factor (1 entity in total) |
| Functional Keywords | disulfide bond, glycoprotein, growth factor, secreted, sialic acid, unfolded protein response, hormone |
| Biological source | Homo sapiens (human) |
| Cellular location | Secreted: P55145 |
| Total number of polymer chains | 1 |
| Total formula weight | 18339.27 |
| Authors | Hellman, M.H.,Peranen, J.,Saarma, M.,Permi, P. (deposition date: 2010-03-12, release date: 2010-11-03, Last modification date: 2011-07-13) |
| Primary citation | Hellman, M.H.,Arumae, U.,Yu, L.-Y.,Lindholm, P.,Peranen, J.,Saarma, M.,Permi, P. Mesencephalic Astrocyte-derived Neurotrophic Factor (MANF) Has a Unique Mechanism to Rescue Apoptotic Neurons J.Biol.Chem., 286:2675-2680, 2011 Cited by PubMed: 21047780DOI: 10.1074/jbc.M110.146738 PDB entries with the same primary citation |
| Experimental method | SOLUTION NMR |
Structure validation
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