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8UTG
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An RNA G-Quadruplex from the NS5 gene in the West Nile Virus Genome
Descriptor: AMMONIUM ION, POTASSIUM ION, RNA (5'-R(*UP*AP*UP*GP*GP*AP*AP*GP*AP*GP*GP*CP*GP*GP*UP*UP*GP*GP*UP*AP*U)-3')
Authors:Terrell, J.R, Le, T.T, Wilson, W.D, Siemer, J.L.
Deposit date:2023-10-31
Release date:2024-06-19
Last modified:2024-07-17
Method:X-RAY DIFFRACTION (1.97 Å)
Cite:Structure of an RNA G-quadruplex from the West Nile virus genome.
Nat Commun, 15, 2024
8BZU
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Double-ion dependent DNA quadruplex structure formed by C.elegans telomeric sequence
Descriptor: DNA (5'-D(*GP*GP*CP*TP*TP*AP*GP*GP*CP*TP*TP*AP*GP*GP*CP*TP*TP*AP*GP*GP*C)-3')
Authors:Lenarcic Zivkovic, M, Trantirek, L.
Deposit date:2022-12-15
Release date:2024-03-13
Method:SOLUTION NMR
Cite:DNA Quadruplex Structure with a Unique Cation Dependency.
Angew.Chem.Int.Ed.Engl., 63, 2024
5CMX
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X-ray structure of the complex between human alpha thrombin and a duplex/quadruplex 31-mer DNA aptamer
Descriptor: D-phenylalanyl-N-[(2S,3S)-6-{[amino(iminio)methyl]amino}-1-chloro-2-hydroxyhexan-3-yl]-L-prolinamide, POTASSIUM ION, RE31, ...
Authors:Russo Krauss, I, Pica, A, Napolitano, V, Sica, F.
Deposit date:2015-07-17
Release date:2016-01-13
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (2.98 Å)
Cite:Different duplex/quadruplex junctions determine the properties of anti-thrombin aptamers with mixed folding.
Nucleic Acids Res., 44, 2016
5UA3
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Crystal Structure of a DNA G-Quadruplex with a Cytosine Bulge
Descriptor: DNA (5'-D(*GP*GP*GP*TP*TP*GP*CP*GP*GP*AP*GP*GP*GP*TP*GP*GP*GP*CP*CP*T)-3'), POTASSIUM ION
Authors:Meier, M, McDougall, M.D, Krahn, N.J, Moya-Torres, A, McRae, E.K.S, Booy, E.P, Patel, T.R, McKenna, S.A, Stetefeld, J.
Deposit date:2016-12-18
Release date:2017-11-22
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.8802 Å)
Cite:Structure and hydrodynamics of a DNA G-quadruplex with a cytosine bulge.
Nucleic Acids Res., 46, 2018
1A6H
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DNA QUADRUPLEX CONTAINING GCGC TETRAD, NMR, 4 STRUCTURES
Descriptor: DNA (5'-D(GP*CP*GP*GP*TP*TP*TP*GP*CP*GP*G)-3')
Authors:Kettani, A, Kumar, R.A, Patel, D.J.
Deposit date:1998-02-25
Release date:1998-06-17
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Solution structure of a DNA quadruplex containing the fragile X syndrome triplet repeat.
J.Mol.Biol., 254, 1995
5DE5
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Crystal structure of the complex between human FMRP RGG motif and G-quadruplex RNA.
Descriptor: Fragile X mental retardation protein 1, POTASSIUM ION, sc1
Authors:Vasilyev, N, Polonskaia, A, Darnell, J.C, Darnell, R.B, Patel, D.J, Serganov, A.
Deposit date:2015-08-25
Release date:2015-09-23
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (3.0011 Å)
Cite:Crystal structure reveals specific recognition of a G-quadruplex RNA by a beta-turn in the RGG motif of FMRP.
Proc.Natl.Acad.Sci.USA, 112, 2015
5DE8
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Crystal structure of the complex between human FMRP RGG motif and G-quadruplex RNA, iridium hexammine bound form.
Descriptor: Fragile X mental retardation protein 1, IRIDIUM HEXAMMINE ION, POTASSIUM ION, ...
Authors:Vasilyev, N, Polonskaia, A, Darnell, J.C, Darnell, R.B, Patel, D.J, Serganov, A.
Deposit date:2015-08-25
Release date:2015-09-23
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (3.1003 Å)
Cite:Crystal structure reveals specific recognition of a G-quadruplex RNA by a beta-turn in the RGG motif of FMRP.
Proc.Natl.Acad.Sci.USA, 112, 2015
5DEA
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Crystal structure of the complex between human FMRP RGG motif and G-quadruplex RNA, cesium bound form.
Descriptor: CESIUM ION, Fragile X mental retardation protein 1, POTASSIUM ION, ...
Authors:Vasilyev, N, Polonskaia, A, Darnell, J.C, Darnell, R.B, Patel, D.J, Serganov, A.
Deposit date:2015-08-25
Release date:2015-09-23
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.7973 Å)
Cite:Crystal structure reveals specific recognition of a G-quadruplex RNA by a beta-turn in the RGG motif of FMRP.
Proc.Natl.Acad.Sci.USA, 112, 2015
2HY9
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Human telomere DNA quadruplex structure in K+ solution hybrid-1 form
Descriptor: DNA (26-MER)
Authors:Dai, J, Punchihewa, C, Jones, R.A, Hurley, L, Yang, D.
Deposit date:2006-08-04
Release date:2007-04-10
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:Structure of the intramolecular human telomeric G-quadruplex in potassium solution: a novel adenine triple formation.
Nucleic Acids Res., 35, 2007
1JJP
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A(GGGG) Pentad-Containing Dimeric DNA Quadruplex Involving Stacked G(anti)G(anti)G(anti)G(syn) Tetrads
Descriptor: 5'-D(*GP*GP*GP*AP*GP*GP*TP*TP*TP*GP*GP*GP*AP*T)-3'
Authors:Zhang, N, Gorin, A, Majumdar, A, Kettani, A, Chernichenko, N, Skripkin, E, Patel, D.J.
Deposit date:2001-07-09
Release date:2001-09-19
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:V-shaped scaffold: a new architectural motif identified in an A x (G x G x G x G) pentad-containing dimeric DNA quadruplex involving stacked G(anti) x G(anti) x G(anti) x G(syn) tetrads.
J.Mol.Biol., 311, 2001
6FQ2
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Structure of minimal sequence for left -handed G-quadruplex formation
Descriptor: DNA (5'-D(*GP*TP*GP*GP*TP*GP*GP*TP*GP*GP*TP*G)-3'), POTASSIUM ION
Authors:Schmitt, E, Mechulam, Y, Phan, A.T, Heddi, B, Bakalar, B.
Deposit date:2018-02-13
Release date:2018-12-05
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.31 Å)
Cite:A Minimal Sequence for Left-Handed G-Quadruplex Formation.
Angew. Chem. Int. Ed. Engl., 58, 2019
1EMQ
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NMR OBSERVATION OF T-TETRADS IN A PARALLEL STRANDED DNA QUADRUPLEX FORMED BY SACCHAROMYCES CEREVISIAE TELOMERE REPEATS
Descriptor: DNA (5'-D(*TP*GP*GP*TP*GP*GP*C)-3')
Authors:Hosur, R.V, Patel, P.K.
Deposit date:2000-03-17
Release date:2000-04-04
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:NMR observation of T-tetrads in a parallel stranded DNA quadruplex formed by Saccharomyces cerevisiae telomere repeats.
Nucleic Acids Res., 27, 1999
1L1H
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Crystal Structure of the Quadruplex DNA-Drug Complex
Descriptor: 3-PYRROLIDIN-1-YL-N-[6-(3-PYRROLIDIN-1-YL-PROPIONYLAMINO)-ACRIDIN-3-YL]-PROPIONAMIDE, 5'-D(*GP*GP*GP*GP*TP*TP*TP*TP*GP*GP*GP*G)-3', POTASSIUM ION
Authors:Haider, S.M, Parkinson, G.N, Neidle, S.
Deposit date:2002-02-16
Release date:2003-02-11
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Structure of a G-quadruplex-Ligand Complex
J.Mol.Biol., 326, 2003
6GZ6
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Structure of a left-handed G-quadruplex
Descriptor: DNA (27-MER), POTASSIUM ION
Authors:Bakalar, B, Heddi, B, Schmitt, E, Mechulam, Y, Phan, A.T.
Deposit date:2018-07-03
Release date:2019-04-24
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.006 Å)
Cite:A Minimal Sequence for Left-Handed G-Quadruplex Formation.
Angew.Chem.Int.Ed.Engl., 58, 2019
6R9L
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A quadruplex hybrid structure with lpp loop orientation and 5 syn residues
Descriptor: DNA (25-MER)
Authors:Karg, B, Weisz, K.
Deposit date:2019-04-03
Release date:2019-07-03
Last modified:2024-06-19
Method:SOLUTION NMR
Cite:Duplex-Guided Refolding into Novel G-Quadruplex (3+1) Hybrid Conformations.
Angew.Chem.Int.Ed.Engl., 58, 2019
6F4Z
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2'F-araG modified quadruplex with flipped G-tract and central tetrad
Descriptor: DNA (5'-D(*GP*GP*GP*AP*TP*GP*GP*GP*AP*CP*AP*CP*AP*GP*(GFL)P*GP*GP*AP*CP*GP*GP*G)-3')
Authors:Dickerhoff, J, Weisz, K.
Deposit date:2017-11-30
Release date:2018-04-25
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Fluorine-Mediated Editing of a G-Quadruplex Folding Pathway.
Chembiochem, 19, 2018
1MY9
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Solution structure of a K+ cation stabilized dimeric RNA quadruplex containing two G:G(:A):G:G(:A) hexads, G:G:G:G tetrads and UUUU loops
Descriptor: 5'-R(*GP*GP*AP*GP*GP*UP*UP*UP*UP*GP*GP*AP*GP*G)-3'
Authors:Liu, H, Matsugami, A, Katahira, M, Uesugi, S.
Deposit date:2002-10-04
Release date:2003-10-07
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:A Dimeric RNA Quadruplex Architecture Comprised of Two G:G(:A):G:G(:A) Hexads, G:G:G:G Tetrads and UUUU Loops
J.Mol.Biol., 322, 2002
6R9K
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A quadruplex hybrid structure with lpp loop orientation and 3 syn residues
Descriptor: DNA (25-MER)
Authors:Karg, B, Weisz, K.
Deposit date:2019-04-03
Release date:2019-07-03
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Duplex-Guided Refolding into Novel G-Quadruplex (3+1) Hybrid Conformations.
Angew.Chem.Int.Ed.Engl., 58, 2019
1C38
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SOLUTION STRUCTURE OF A QUADRUPLEX FORMING DNA AND ITS INTERMEDIATE
Descriptor: DNA (5'-D(*GP*GP*TP*TP*GP*GP*TP*GP*TP*GP*GP*TP*TP*GP*G)-3'), POTASSIUM ION
Authors:Bolton, P.H, Marathias, V.M, Wang, K.
Deposit date:1999-07-25
Release date:1999-08-25
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Structures of the potassium-saturated, 2:1, and intermediate, 1:1, forms of a quadruplex DNA.
Nucleic Acids Res., 28, 2000
139D
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BU of 139d by Molmil
SOLUTION STRUCTURE OF A PARALLEL-STRANDED G-QUADRUPLEX DNA
Descriptor: DNA (5'-D(*TP*TP*GP*GP*GP*GP*T)-3')
Authors:Patel, D.J, Wang, Y.
Deposit date:1993-09-28
Release date:1994-01-31
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Solution structure of a parallel-stranded G-quadruplex DNA.
J.Mol.Biol., 234, 1993
6KVB
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Structure of an intra-locked G-quadruplex
Descriptor: DNA (28-mer)
Authors:Maity, A, Winnerdy, F.R, Chang, W.D, Chen, G, Phan, A.T.
Deposit date:2019-09-03
Release date:2020-03-04
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:Intra-locked G-quadruplex structures formed by irregular DNA G-rich motifs.
Nucleic Acids Res., 48, 2020
1O0K
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BU of 1o0k by Molmil
Structure of the First Parallel DNA Quadruplex-drug Complex
Descriptor: 5'-D(*TP*GP*GP*GP*GP*T)-3', DAUNOMYCIN, SODIUM ION
Authors:Clark, G.R, Pytel, P.D, Squire, C.J, Neidle, S.
Deposit date:2003-02-22
Release date:2003-04-15
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.17 Å)
Cite:Structure of the First Parallel DNA Quadruplex-drug Complex
J.Am.Chem.Soc., 125, 2003
1VYA
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Identification and characterization of the first plant G-quadruplex binding protein encoded by the Zea mays L. nucleoside diphosphate1 gene, ZmNDPK1
Descriptor: Nucleoside diphosphate kinase
Authors:Kopylov, M, Stroupe, M.E.
Deposit date:2014-08-14
Release date:2015-04-08
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:The Maize (Zea mays L.) Nucleoside Diphosphate Kinase1 (ZmNDPK1) Gene Encodes a Human NM23-H2 Homologue That Binds and Stabilizes G-Quadruplex DNA.
Biochemistry, 54, 2015
6CCW
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Hybrid-2 form Human Telomeric G Quadruplex in Complex with Epiberberine
Descriptor: DNA (26-MER), Epiberberine
Authors:Lin, C, Yang, D.Z.
Deposit date:2018-02-07
Release date:2018-06-20
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Molecular Recognition of the Hybrid-2 Human Telomeric G-Quadruplex by Epiberberine: Insights into Conversion of Telomeric G-Quadruplex Structures.
Angew. Chem. Int. Ed. Engl., 57, 2018
1NP9
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Structure of the parallel-stranded DNA quadruplex d(TTAGGGA)4 containing the human telomeric repeat
Descriptor: 5'-D(*TP*TP*AP*GP*GP*GP*T)-3'
Authors:Gavathiotis, E, Searle, M.S.
Deposit date:2003-01-17
Release date:2003-09-16
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Structure of the parallel-stranded DNA quadruplex d(TTAGGGT)4 containing the human telomeric repeat: evidence for A-tetrad formation from NMR and molecular dynamics simulations.
ORG.BIOMOL.CHEM., 1, 2003

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