1O0K

Structure of the First Parallel DNA Quadruplex-drug Complex

Summary for 1O0K

• Entry DOI: 10.2210/pdb1o0k/pdb
• Descriptor: 5'-D(*TP*GP*GP*GP*GP*T)-3', SODIUM ION, DAUNOMYCIN, ... (4 entities in total)
• Functional Keywords: g-4 quadruplex drug complex, parallel quadruplex, dna
• Total number of polymer chains: 4
• Total formula weight: 9172.53

Authors

Clark, G.R.,Pytel, P.D.,Squire, C.J.,Neidle, S. (deposition date: 2003-02-22, release date: 2003-04-15, Last modification date: 2024-04-03)

• Primary citation: Clark, G.R.,Pytel, P.D.,Squire, C.J.,Neidle, S.; Structure of the First Parallel DNA Quadruplex-drug Complex; J.Am.Chem.Soc., 125:4066-4067, 2003; PubMed: 12670225; DOI: 10.1021/ja0297988

Experimental method

X-RAY DIFFRACTION (1.17 Å)