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6VLR
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BG505 SOSIP.v5.2 in complex with rhesus macaque Fab RM20E1 and PGT122 Fab
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, BG505 SOSIPv5.2 gp41, ...
Authors:Cottrell, C.A, Ward, A.B.
Deposit date:2020-01-24
Release date:2020-06-24
Last modified:2024-10-09
Method:ELECTRON MICROSCOPY (4.42 Å)
Cite:Mapping the immunogenic landscape of near-native HIV-1 envelope trimers in non-human primates.
Plos Pathog., 16, 2020
6VN0
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BU of 6vn0 by Molmil
BG505 SOSIP.v4.1 in complex with rhesus macaque Fab RM20F
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein gp160, ...
Authors:Cottrell, C.A, Shin, M, Ward, A.B.
Deposit date:2020-01-29
Release date:2020-06-24
Last modified:2024-10-16
Method:ELECTRON MICROSCOPY (4.25 Å)
Cite:Mapping the immunogenic landscape of near-native HIV-1 envelope trimers in non-human primates.
Plos Pathog., 16, 2020
6VO0
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BU of 6vo0 by Molmil
BG505 SOSIP.v5.2 in complex with rabbit Fab 43A2
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 43A2 heavy chain, ...
Authors:Nogal, B, Cottrell, C.A, Ward, A.B.
Deposit date:2020-01-29
Release date:2020-07-01
Last modified:2024-10-16
Method:ELECTRON MICROSCOPY (3.52 Å)
Cite:HIV envelope trimer-elicited autologous neutralizing antibodies bind a region overlapping the N332 glycan supersite.
Sci Adv, 6, 2020
6VO1
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BU of 6vo1 by Molmil
BG505 SOSIP.v5.2 in complex with rhesus macaque Fab RM20J
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein gp120, ...
Authors:Cottrell, C.A, Ward, A.B.
Deposit date:2020-01-29
Release date:2020-07-01
Last modified:2024-10-30
Method:ELECTRON MICROSCOPY (3.88 Å)
Cite:Mapping the immunogenic landscape of near-native HIV-1 envelope trimers in non-human primates.
Plos Pathog., 16, 2020
6VPX
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BU of 6vpx by Molmil
Nanodisc of full-length HIV-1 Envelope glycoprotein clone AMC011 in complex with one PGT151 Fab and three 10E8 Fabs
Descriptor: (2R)-3-(phosphonooxy)propane-1,2-diyl dihexanoate, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Rantalainen, K, Ward, A.B.W.
Deposit date:2020-02-04
Release date:2020-04-22
Last modified:2020-07-29
Method:ELECTRON MICROSCOPY (5 Å)
Cite:HIV-1 Envelope and MPER Antibody Structures in Lipid Assemblies.
Cell Rep, 31, 2020
6VY2
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BU of 6vy2 by Molmil
Cryo-EM structure of M1214_N1 Fab in complex with CH505 TF chimeric SOSIP.664 Env trimer
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Glycoprotein 120, ...
Authors:Chan, K.-W, Kong, X.P.
Deposit date:2020-02-25
Release date:2020-05-06
Last modified:2024-11-13
Method:ELECTRON MICROSCOPY (4.86 Å)
Cite:VSV-Displayed HIV-1 Envelope Identifies Broadly Neutralizing Antibodies Class-Switched to IgG and IgA.
Cell Host Microbe, 27, 2020
6VZI
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BU of 6vzi by Molmil
Crystal Structure of HIV-1 CAP256 RnS-3mut-2G-SOSIP.664 Prefusion Env Trimer in Complex with Human Antibodies 3H109L and 35O22 at 3.5 Angstrom
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 35O22 scFv heavy chain, ...
Authors:Lai, Y.-T, Kwong, P.D.
Deposit date:2020-02-28
Release date:2020-04-15
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (2.716 Å)
Cite:Development of a 3Mut-Apex-Stabilized Envelope Trimer That Expands HIV-1 Neutralization Breadth When Used To Boost Fusion Peptide-Directed Vaccine-Elicited Responses.
J.Virol., 94, 2020
6W03
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BU of 6w03 by Molmil
Crystal Structure of HIV-1 BG505 DS-SOSIP.3mut Prefusion Env Trimer in Complex with Human Antibodies 3H109L and 35O22 at 3.3 Angstrom
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 35O22 scFv heavy chain, ...
Authors:Lai, Y.-T, Kwong, P.D.
Deposit date:2020-02-28
Release date:2020-04-15
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Development of a 3Mut-Apex-Stabilized Envelope Trimer That Expands HIV-1 Neutralization Breadth When Used To Boost Fusion Peptide-Directed Vaccine-Elicited Responses.
J.Virol., 94, 2020
6WIX
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BU of 6wix by Molmil
Crystal Structure of HIV-1 MI369 RnS-DS.SOSIP Prefusion Env Trimer in Complex with Human Antibodies 3H109L and 35O22 at 3.5 Angstrom
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Lai, Y.-T, Olia, A, Kwong, P.D.
Deposit date:2020-04-10
Release date:2020-11-25
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.67 Å)
Cite:Automated Design by Structure-Based Stabilization and Consensus Repair to Achieve Prefusion-Closed Envelope Trimers in a Wide Variety of HIV Strains.
Cell Rep, 33, 2020
6X5B
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BU of 6x5b by Molmil
Symmetric model of CD4- and 17-bound B41 HIV-1 Env SOSIP in complex with small molecule GO52
Descriptor: 17b Fab heavy chain, 17b Fab light chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Ozorowski, G, Torres, J.L, Ward, A.B.
Deposit date:2020-05-25
Release date:2020-10-21
Last modified:2020-12-09
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:A Strain-Specific Inhibitor of Receptor-Bound HIV-1 Targets a Pocket near the Fusion Peptide.
Cell Rep, 33, 2020
6X5C
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BU of 6x5c by Molmil
Asymmetric model of CD4-bound B41 HIV-1 Env SOSIP in complex with small molecule GO52
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein gp160, ...
Authors:Ozorowski, G, Torres, J.L, Ward, A.B.
Deposit date:2020-05-25
Release date:2020-10-21
Last modified:2024-11-06
Method:ELECTRON MICROSCOPY (4.04 Å)
Cite:A Strain-Specific Inhibitor of Receptor-Bound HIV-1 Targets a Pocket near the Fusion Peptide.
Cell Rep, 33, 2020
6X96
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BU of 6x96 by Molmil
Cryo-EM model of HIV-1 Env BG505 SOSIP.664 in complex with rabbit monoclonal antibody 10A fragment antigen binding variable domain
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, BG505 HIV-1 Env gp120, ...
Authors:Ozorowski, G, Cottrell, C.A, Ward, A.B.
Deposit date:2020-06-02
Release date:2021-12-08
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Limited breadth of anti-HIV Env glycan hole antibodies is further hindered by strain-specific peptide interactions
To Be Published
6X97
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BU of 6x97 by Molmil
Cryo-EM model of HIV-1 Env BG505 SOSIP.664 in complex with rabbit monoclonal antibody 11A fragment antigen binding variable domain
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, BG505 HIV-1 Env gp120, ...
Authors:Ozorowski, G, Cottrell, C.A, Ward, A.B.
Deposit date:2020-06-02
Release date:2021-12-08
Last modified:2024-11-13
Method:ELECTRON MICROSCOPY (3.65 Å)
Cite:Limited breadth of anti-HIV Env glycan hole antibodies is further hindered by strain-specific peptide interactions
To Be Published
6X98
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BU of 6x98 by Molmil
Cryo-EM model of HIV-1 Env BG505 SOSIP.664 in complex with rabbit monoclonal antibody 11B fragment antigen binding variable domain
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, BG505 HIV-1 Env gp120, ...
Authors:Ozorowski, G, Cottrell, C.A, Ward, A.B.
Deposit date:2020-06-02
Release date:2021-12-08
Last modified:2024-10-30
Method:ELECTRON MICROSCOPY (3.38 Å)
Cite:Limited breadth of anti-HIV Env glycan hole antibodies is further hindered by strain-specific peptide interactions
To Be Published
6X9R
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BU of 6x9r by Molmil
HIV-1 Envelope Glycoprotein BG505 SOSIP.664 expressed in HEK293F cells in complex with RM20A3 Fab
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, HIV-1 Envelope Glycoprotein BG505 SOSIP.664 gp120, ...
Authors:Berndsen, Z.T, Ward, A.B.
Deposit date:2020-06-03
Release date:2020-11-04
Last modified:2024-11-13
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Visualization of the HIV-1 Env glycan shield across scales.
Proc.Natl.Acad.Sci.USA, 117, 2020
6X9S
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BU of 6x9s by Molmil
HIV-1 Envelope Glycoprotein BG505 SOSIP.664 expressed in stable CHO cells in complex with RM20A3 Fab
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, HIV-1 Envelope Glycoprotein BG505 SOSIP.664 gp120, ...
Authors:Berndsen, Z.T, Ward, A.B.
Deposit date:2020-06-03
Release date:2020-11-04
Last modified:2024-11-13
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Visualization of the HIV-1 Env glycan shield across scales.
Proc.Natl.Acad.Sci.USA, 117, 2020
6X9T
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BU of 6x9t by Molmil
HIV-1 Envelope Glycoprotein BG505 SOSIP.664 expressed in HEK293S cells in complex with RM20A3 Fab
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, HIV-1 Envelope Glycoprotein BG505 SOSIP.664 gp120, ...
Authors:Berndsen, Z.T, Ward, A.B.
Deposit date:2020-06-03
Release date:2020-11-04
Last modified:2024-10-23
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Visualization of the HIV-1 Env glycan shield across scales.
Proc.Natl.Acad.Sci.USA, 117, 2020
6X9U
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BU of 6x9u by Molmil
HIV-1 Envelope Glycoprotein BG505 SOSIP.664, expressed in HEK293S cells and partially deglycosylated by endoglycosidase H, in complex with RM20A3 Fab
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, HIV-1 Envelope Glycoprotein BG505 SOSIP.664 gp120, ...
Authors:Berndsen, Z.T, Ward, A.B.
Deposit date:2020-06-03
Release date:2020-11-04
Last modified:2024-10-09
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Visualization of the HIV-1 Env glycan shield across scales.
Proc.Natl.Acad.Sci.USA, 117, 2020
6X9V
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BU of 6x9v by Molmil
HIV-1 Envelope Glycoprotein BG505 SOSIP.664, expressed in HEK293S cells and deglycosylated by endoglycosidase H, in complex with RM20A3 Fab
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, HIV-1 Envelope Glycoprotein BG505 SOSIP.664 gp120, ...
Authors:Berndsen, Z.T, Ward, A.B.
Deposit date:2020-06-03
Release date:2020-11-04
Last modified:2024-10-16
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Visualization of the HIV-1 Env glycan shield across scales.
Proc.Natl.Acad.Sci.USA, 117, 2020
6XRT
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BU of 6xrt by Molmil
Cryo-EM structure of SHIV-elicited RHA1.V2.01 in complex with HIV-1 Env BG505 DS-SOSIP.664
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein gp160, ...
Authors:Gorman, J, Kwong, P.D.
Deposit date:2020-07-13
Release date:2020-10-07
Last modified:2024-10-30
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Recapitulation of HIV-1 Env-antibody coevolution in macaques leading to neutralization breadth.
Science, 371, 2021
7AEJ
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BU of 7aej by Molmil
Crystal structure of asymmetric HIV-1 gp41 containing all membrane anchors
Descriptor: 2H10, Envelope glycoprotein gp160,Envelope glycoprotein gp160
Authors:Caillat, C, Guilligay, D, Weissenhorn, W.
Deposit date:2020-09-17
Release date:2021-05-26
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (3.8 Å)
Cite:Structure of HIV-1 gp41 with its membrane anchors targeted by neutralizing antibodies.
Elife, 10, 2021
7KDE
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BU of 7kde by Molmil
BG505 SOSIP.664 in complex with the V3-targeting rhesus macaque antibody 1485 and human gp120-gp41 interface antibody 8ANC195
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Barnes, C.O, Bjorkman, P.J.
Deposit date:2020-10-08
Release date:2020-10-28
Last modified:2024-10-30
Method:ELECTRON MICROSCOPY (3.55 Å)
Cite:A broadly neutralizing macaque monoclonal antibody against the HIV-1 V3-Glycan patch.
Elife, 9, 2020
7L6O
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BU of 7l6o by Molmil
Cryo-EM structure of HIV-1 Env CH848.3.D0949.10.17chim.6R.DS.SOSIP.664
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CH848.3.D0949.10.17chim.6R.DS.SOSIP.664 - gp120, ...
Authors:Manne, K, Edwards, R.J, Acharya, P.
Deposit date:2020-12-23
Release date:2021-04-14
Last modified:2021-06-09
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Fab-dimerized glycan-reactive antibodies are a structural category of natural antibodies.
Cell, 184, 2021
7L7T
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BU of 7l7t by Molmil
BG505 SOSIP reconstructed from a designed nanoparticle, BG505 SOSIP-T33-31 (Component A)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, BG505 SOSIP.v5.2(7S) - gp120, ...
Authors:Antanasijevic, A, Cannac, F, Sewall, L.M, Ward, A.B.
Deposit date:2020-12-30
Release date:2021-08-04
Last modified:2021-08-25
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Polyclonal antibody responses to HIV Env immunogens resolved using cryoEM.
Nat Commun, 12, 2021
7L7U
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BU of 7l7u by Molmil
BG505 SOSIP reconstructed from a designed nanoparticle, BG505 SOSIP-T33-31 (Component B)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, BG505 SOSIP.v5.2(7S) - gp120, ...
Authors:Antanasijevic, A, Froes Rocha, R, Sewall, L.M, Ward, A.B.
Deposit date:2020-12-30
Release date:2021-08-04
Last modified:2024-11-06
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Polyclonal antibody responses to HIV Env immunogens resolved using cryoEM.
Nat Commun, 12, 2021

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