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4V6Y
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BU of 4v6y by Molmil
E. coli 70S-fMetVal-tRNAVal-tRNAfMet complex in classic pre-translocation state (pre1a)
Descriptor: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Blau, C, Bock, L.V, Schroder, G.F, Davydov, I, Fischer, N, Stark, H, Rodnina, M.V, Vaiana, A.C, Grubmuller, H.
Deposit date:2013-10-14
Release date:2014-07-09
Last modified:2019-12-18
Method:ELECTRON MICROSCOPY (12 Å)
Cite:Energy barriers and driving forces in tRNA translocation through the ribosome.
Nat.Struct.Mol.Biol., 20, 2013
4V6Z
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BU of 4v6z by Molmil
E. coli 70S-fMetVal-tRNAVal-tRNAfMet complex in classic pre-translocation state (pre1b)
Descriptor: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Blau, C, Bock, L.V, Schroder, G.F, Davydov, I, Fischer, N, Stark, H, Rodnina, M.V, Vaiana, A.C, Grubmuller, H.
Deposit date:2013-10-14
Release date:2014-07-09
Last modified:2019-12-18
Method:ELECTRON MICROSCOPY (12 Å)
Cite:Energy barriers and driving forces in tRNA translocation through the ribosome.
Nat.Struct.Mol.Biol., 20, 2013
4V79
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BU of 4v79 by Molmil
E. coli 70S-fMetVal-tRNAVal-tRNAfMet complex in intermediate post-translocation state (post3b)
Descriptor: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Blau, C, Bock, L.V, Schroder, G.F, Davydov, I, Fischer, N, Stark, H, Rodnina, M.V, Vaiana, A.C, Grubmuller, H.
Deposit date:2013-10-14
Release date:2014-07-09
Last modified:2024-10-16
Method:ELECTRON MICROSCOPY (15 Å)
Cite:Energy barriers and driving forces in tRNA translocation through the ribosome.
Nat.Struct.Mol.Biol., 20, 2013
4V70
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BU of 4v70 by Molmil
E. coli 70S-fMetVal-tRNAVal-tRNAfMet complex in intermediate pre-translocation state (pre3)
Descriptor: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Blau, C, Bock, L.V, Schroder, G.F, Davydov, I, Fischer, N, Stark, H, Rodnina, M.V, Vaiana, A.C, Grubmuller, H.
Deposit date:2013-10-14
Release date:2014-07-09
Last modified:2019-12-18
Method:ELECTRON MICROSCOPY (17 Å)
Cite:Energy barriers and driving forces in tRNA translocation through the ribosome.
Nat.Struct.Mol.Biol., 20, 2013
4V7A
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BU of 4v7a by Molmil
E. coli 70S-fMetVal-tRNAVal post-translocation complex (post4)
Descriptor: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Blau, C, Bock, L.V, Schroder, G.F, Davydov, I, Fischer, N, Stark, H, Rodnina, M.V, Vaiana, A.C, Grubmuller, H.
Deposit date:2013-10-14
Release date:2014-07-09
Last modified:2024-10-16
Method:ELECTRON MICROSCOPY (9 Å)
Cite:Energy barriers and driving forces in tRNA translocation through the ribosome.
Nat.Struct.Mol.Biol., 20, 2013
8CGK
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BU of 8cgk by Molmil
Lincomycin and Avilamycin bound to the 50S subunit
Descriptor: (2R,3S,4R,6S)-4-hydroxy-6-{[(2R,3aR,4R,4'R,5'S,6S,6'R,7aR)-4'-hydroxy-6-{[(2S,3R,4R,5S,6R)-3-hydroxy-2-{[(2R,3S,4S,5S,6S)-4-hydroxy-6-({(2R,3aS,3a'R,6S,6'R,7R,7'R,7aR,7a'R)-7'-hydroxy-7'-[(1S)-1-hydroxyethyl]-6'-methyl-7-[(2-methylpropanoyl)oxy]octahydro-4H-2,4'-spirobi[[1,3]dioxolo[4,5-c]pyran]-6-yl}oxy)-5-methoxy-2-(methoxymethyl)tetrahydro-2H-pyran-3-yl]oxy}-5-methoxy-6-methyltetrahydro-2H-pyran-4-yl]oxy}-4,6',7a-trimethyloctahydro-4H-spiro[1,3-dioxolo[4,5-c]pyran-2,2'-pyran]-5'-yl]oxy}-2-methyltetrahydro-2H-pyran-3-yl 3,5-dichloro-4-hydroxy-2-methoxy-6-methylbenzoate (non-preferred name), 23S rRNA, 50S ribosomal protein L15, ...
Authors:Paternoga, H, Crowe-McAuliffe, C, Beckert, B, Wilson, D.N.
Deposit date:2023-02-05
Release date:2023-07-19
Last modified:2023-11-15
Method:ELECTRON MICROSCOPY (1.64 Å)
Cite:Structural conservation of antibiotic interaction with ribosomes.
Nat.Struct.Mol.Biol., 30, 2023
8CGD
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BU of 8cgd by Molmil
Clindamycin bound to the 50S subunit
Descriptor: 23S rRNA, 50S ribosomal protein L15, 50S ribosomal protein L25, ...
Authors:Paternoga, H, Koller, T.O, Beckert, B, Wilson, D.N.
Deposit date:2023-02-03
Release date:2023-07-26
Last modified:2023-11-15
Method:ELECTRON MICROSCOPY (1.98 Å)
Cite:Structural conservation of antibiotic interaction with ribosomes.
Nat.Struct.Mol.Biol., 30, 2023
8CEU
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BU of 8ceu by Molmil
Retapamulin and Capreomycin bound to the 50S subunit
Descriptor: 23S rRNA, 50S ribosomal protein L15, 50S ribosomal protein L25, ...
Authors:Paternoga, H, Beckert, B, Wilson, D.N.
Deposit date:2023-02-02
Release date:2023-07-26
Last modified:2023-11-15
Method:ELECTRON MICROSCOPY (1.83 Å)
Cite:Structural conservation of antibiotic interaction with ribosomes.
Nat.Struct.Mol.Biol., 30, 2023
8CAM
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BU of 8cam by Molmil
Evernimicin bound to the 50S subunit
Descriptor: 23S rRNA, 50S ribosomal protein L15, 50S ribosomal protein L25, ...
Authors:Paternoga, H, Crowe-McAuliffe, C, Novacek, J, Wilson, D.N.
Deposit date:2023-01-24
Release date:2023-07-26
Last modified:2023-11-15
Method:ELECTRON MICROSCOPY (1.86 Å)
Cite:Structural conservation of antibiotic interaction with ribosomes.
Nat.Struct.Mol.Biol., 30, 2023
8CGV
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BU of 8cgv by Molmil
Tiamulin bound to the 50S subunit
Descriptor: 23S rRNA, 50S ribosomal protein L15, 50S ribosomal protein L25, ...
Authors:Paternoga, H, Crowe-McAuliffe, C, Novacek, J, Wilson, D.N.
Deposit date:2023-02-06
Release date:2023-08-02
Last modified:2023-11-15
Method:ELECTRON MICROSCOPY (1.66 Å)
Cite:Structural conservation of antibiotic interaction with ribosomes.
Nat.Struct.Mol.Biol., 30, 2023
8R55
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BU of 8r55 by Molmil
Bacillus subtilis MutS2-collided disome complex (collided 70S)
Descriptor: 16S rRNA (1533-MER), 23S RNA (2887-MER), 30S ribosomal protein S10, ...
Authors:Park, E, Mackens-Kiani, T, Berhane, R, Esser, H, Erdenebat, C, Burroughs, A.M, Berninghausen, O, Aravind, L, Beckmann, R, Green, R, Buskirk, A.R.
Deposit date:2023-11-16
Release date:2024-01-17
Last modified:2024-02-28
Method:ELECTRON MICROSCOPY (3.57 Å)
Cite:B. subtilis MutS2 splits stalled ribosomes into subunits without mRNA cleavage.
Embo J., 43, 2024
8CAS
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BU of 8cas by Molmil
Cryo-EM structure of native Otu2-bound ubiquitinated 48S initiation complex (partial)
Descriptor: 18S ribosomal RNA, 40S ribosomal protein S0-A, 40S ribosomal protein S1-A, ...
Authors:Ikeuchi, K, Buschauer, R, Cheng, J, Berninghausen, O, Becker, T, Beckmann, R.
Deposit date:2023-01-24
Release date:2023-05-24
Last modified:2024-07-24
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Molecular basis for recognition and deubiquitination of 40S ribosomes by Otu2.
Nat Commun, 14, 2023
8CAH
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BU of 8cah by Molmil
Cryo-EM structure of native Otu2-bound ubiquitinated 43S pre-initiation complex
Descriptor: 18S ribosomal RNA, 40S ribosomal protein S0-A, 40S ribosomal protein S1-A, ...
Authors:Ikeuchi, K, Buschauer, R, Cheng, J, Berninghausen, O, Becker, T, Beckmann, R.
Deposit date:2023-01-24
Release date:2023-05-24
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Molecular basis for recognition and deubiquitination of 40S ribosomes by Otu2.
Nat Commun, 14, 2023
4V91
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BU of 4v91 by Molmil
Kluyveromyces lactis 80S ribosome in complex with CrPV-IRES
Descriptor: 25S RRNA, 5.8S RRNA, 5S RRNA, ...
Authors:Fernandez, I.S, Bai, X, Scheres, S.H.W, Ramakrishnan, V.
Deposit date:2014-03-21
Release date:2014-07-09
Last modified:2019-12-11
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Initiation of Translation by Cricket Paralysis Virus Ires Requires its Translocation in the Ribosome.
Cell(Cambridge,Mass.), 157, 2014
6ND4
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BU of 6nd4 by Molmil
Conformational switches control early maturation of the eukaryotic small ribosomal subunit
Descriptor: 18S rRNA 5' domain start, 5'ETS rRNA, Bud21, ...
Authors:Hunziker, M, Barandun, J, Klinge, S.
Deposit date:2018-12-13
Release date:2019-06-19
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (4.3 Å)
Cite:Conformational switches control early maturation of the eukaryotic small ribosomal subunit.
Elife, 8, 2019
3N2D
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BU of 3n2d by Molmil
Crystal Structure of the Complex of type I Ribosome inactivating protein with hexapeptide Ser-Asp-Asp-Asp-Met-Gly at 2.2 A resolution
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 6-meric peptide from 60S acidic ribosomal protein P2-beta, Ribosome inactivating protein
Authors:Kushwaha, G.S, Prem Kumar, R, Sinha, M, Bhushan, A, Kaur, P, Sharma, S, Singh, T.P.
Deposit date:2010-05-18
Release date:2010-07-28
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.22 Å)
Cite:Crystal Structure of the Complex of type I Ribosome inactivating protein with hexapeptide Ser-Asp-Asp-Asp-Met-Gly at 2.2 A resolution
To be Published
3U6T
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BU of 3u6t by Molmil
Crystal structure of the complex of type I Ribosome inactivating protein in complex with Kanamycin at 1.85 A
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, KANAMYCIN A, ...
Authors:Yamini, S, Pandey, S, Kushwaha, G.S, Sinha, M, Bhushan, A, Kaur, P, Sharma, S, Singh, T.P.
Deposit date:2011-10-13
Release date:2011-11-16
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Crystal structure of the complex of type I Ribosome inactivating protein in complex with Kanamycin at 1.85 A
To be Published
3U8F
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BU of 3u8f by Molmil
Crystal structure of the complex of type I Ribosome inactivating protein in complex with Mycolic acid at 1.8 A resolution
Descriptor: (2R,3R)-2-hexyl-3-hydroxytridecanoic acid, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, ...
Authors:Yamini, S, Pandey, S, Sinha, M, Kaur, P, Sharma, S, Singh, T.P.
Deposit date:2011-10-17
Release date:2011-11-16
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal structure of the complex of type I Ribosome inactivating protein in complex with Mycolic acid at 1.8 A resolution
To be Published
8W51
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BU of 8w51 by Molmil
Structure of YchF(H114A) on E.coli 50S ribosomal subunit
Descriptor: 23S rRNA, 50S ribosomal protein L13, 50S ribosomal protein L14, ...
Authors:Yu, T, Li, X, Zeng, F.
Deposit date:2023-08-25
Release date:2024-08-28
Method:ELECTRON MICROSCOPY (2.4 Å)
Cite:Structure basis of translation regulation by YchF bound to ribosome
To Be Published
3J92
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BU of 3j92 by Molmil
Structure and assembly pathway of the ribosome quality control complex
Descriptor: 28S rRNA, 5.8S rRNA, 5S rRNA, ...
Authors:Shao, S, Brown, A, Santhanam, B, Hegde, R.S.
Deposit date:2014-12-02
Release date:2015-01-21
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Structure and Assembly Pathway of the Ribosome Quality Control Complex.
Mol.Cell, 57, 2015
7A5J
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BU of 7a5j by Molmil
Structure of the split human mitoribosomal large subunit with P-and E-site mt-tRNAs
Descriptor: 16S rRNA, 39S ribosomal protein L10, mitochondrial, ...
Authors:Desai, N, Yang, H, Chandrasekaran, V, Kazi, R, Minczuk, M, Ramakrishnan, V.
Deposit date:2020-08-21
Release date:2020-12-23
Last modified:2023-03-15
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Elongational stalling activates mitoribosome-associated quality control.
Science, 370, 2020
3IZD
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BU of 3izd by Molmil
Model of the large subunit RNA expansion segment ES27L-out based on a 6.1 A cryo-EM map of Saccharomyces cerevisiae translating 80S ribosome. 3IZD is a small part (an expansion segment) which is in an alternative conformation to what is in already 3IZF.
Descriptor: rRNA expansion segment ES27L in an "out" conformation
Authors:Armache, J.-P, Jarasch, A, Anger, A.M, Villa, E, Becker, T, Bhushan, S, Jossinet, F, Habeck, M, Dindar, G, Franckenberg, S, Marquez, V, Mielke, T, Thomm, M, Berninghausen, O, Beatrix, B, Soeding, J, Westhof, E, Wilson, D.N, Beckmann, R.
Deposit date:2010-10-13
Release date:2010-12-01
Last modified:2024-02-21
Method:ELECTRON MICROSCOPY (8.6 Å)
Cite:Cryo-EM structure and rRNA model of a translating eukaryotic 80S ribosome at 5.5-A resolution.
Proc.Natl.Acad.Sci.USA, 107, 2010
7A5H
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BU of 7a5h by Molmil
Structure of the split human mitoribosomal large subunit with rescue factors mtRF-R and MTRES1
Descriptor: 16S rRNA, 39S ribosomal protein L10, mitochondrial, ...
Authors:Desai, N, Yang, H, Chandrasekaran, V, Kazi, R, Minczuk, M, Ramakrishnan, V.
Deposit date:2020-08-21
Release date:2020-12-23
Last modified:2023-03-01
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Elongational stalling activates mitoribosome-associated quality control.
Science, 370, 2020
2OTL
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BU of 2otl by Molmil
Girodazole bound to the large subunit of Haloarcula marismortui
Descriptor: 23S ribosomal RNA, 50S ribosomal protein L10E, 50S ribosomal protein L10e, ...
Authors:Blaha, G, Schroeder, S.J, Tirado-Rives, J.
Deposit date:2007-02-08
Release date:2007-04-03
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:The Structures of Antibiotics Bound to the E Site Region of the 50 S Ribosomal Subunit of Haloarcula marismortui: 13-Deoxytedanolide and Girodazole.
J.Mol.Biol., 367, 2007
7UQB
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BU of 7uqb by Molmil
Nucleoplasmic pre-60S intermediate of the Nog2 containing pre-rotation state from a SPB1-D52A strain with AlF4
Descriptor: 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 25S rRNA, 5.8S rRNA, ...
Authors:Sekulski, K, Cruz, V.E, Weirich, C.S, Erzberger, J.P.
Deposit date:2022-04-19
Release date:2023-03-15
Last modified:2024-06-12
Method:ELECTRON MICROSCOPY (2.43 Å)
Cite:rRNA methylation by Spb1 regulates the GTPase activity of Nog2 during 60S ribosomal subunit assembly.
Nat Commun, 14, 2023

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