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3L6X
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BU of 3l6x by Molmil
Crystal structure of p120 catenin in complex with E-cadherin
Descriptor: Catenin delta-1, E-cadherin, SULFATE ION
Authors:Ishiyama, N, Lee, S.-H, Liu, S, Li, G.-Y, Smith, M.J, Reichardt, L.F, Ikura, M.
Deposit date:2009-12-27
Release date:2010-04-21
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Dynamic and static interactions between p120 catenin and E-cadherin regulate the stability of cell-cell adhesion.
Cell(Cambridge,Mass.), 141, 2010
3HSF
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BU of 3hsf by Molmil
HEAT SHOCK TRANSCRIPTION FACTOR (HSF)
Descriptor: HEAT SHOCK TRANSCRIPTION FACTOR
Authors:Damberger, F.F, Pelton, J.G, Liu, C, Cho, H, Harrison, C.J, Nelson, H.C.M, Wemmer, D.E.
Deposit date:1995-08-07
Release date:1995-11-14
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Refined solution structure and dynamics of the DNA-binding domain of the heat shock factor from Kluyveromyces lactis.
J.Mol.Biol., 254, 1995
3HMS
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BU of 3hms by Molmil
Crystal Crystal structure of the N-terminal fragment (28-126) of the human hepatocyte growth factor/scatter factor, orthorhombic crystal form
Descriptor: Hepatocyte growth factor, SULFATE ION
Authors:Tolbert, W.D.
Deposit date:2009-05-29
Release date:2010-06-09
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structural basis for agonism and antagonism of hepatocyte growth factor.
Proc.Natl.Acad.Sci.USA, 107, 2010
3E1U
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BU of 3e1u by Molmil
The Crystal Structure of the Anti-Viral APOBEC3G Catalytic Domain
Descriptor: DNA dC->dU-editing enzyme APOBEC-3G, ZINC ION
Authors:Holden, L, Prochnow, C, Chang, Y.P, Bransteitter, R, Chelico, L, Sen, U, Stevens, R.C, Goodman, R.F, Chen, X.S.
Deposit date:2008-08-04
Release date:2008-10-07
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structure of the anti-viral APOBEC3G catalytic domain and functional implications.
Nature, 456, 2008
3E4Z
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BU of 3e4z by Molmil
Crystal structure of human insulin degrading enzyme in complex with insulin-like growth factor II
Descriptor: Insulin-degrading enzyme, Insulin-like growth factor II, ZINC ION
Authors:Guo, Q, Manolopoulou, M, Tang, W.-J.
Deposit date:2008-08-12
Release date:2009-08-18
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.28 Å)
Cite:Molecular Basis for the Recognition and Cleavages of IGF-II, TGF-alpha, and Amylin by Human Insulin-Degrading Enzyme.
J.Mol.Biol., 395, 2010
3EBE
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BU of 3ebe by Molmil
Crystal structure of xenopus laevis replication initiation factor MCM10 internal domain
Descriptor: Protein MCM10 homolog, ZINC ION
Authors:Warren, E.M, Eichman, B.F.
Deposit date:2008-08-27
Release date:2008-12-09
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural basis for DNA binding by replication initiator mcm10.
Structure, 16, 2008
3HMT
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BU of 3hmt by Molmil
Crystal structure of the N-terminal fragment (28-126) of the human hepatocyte growth factor/scatter factor, trigonal crystal form
Descriptor: Hepatocyte growth factor
Authors:Tolbert, W.D.
Deposit date:2009-05-29
Release date:2010-06-09
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural basis for agonism and antagonism of hepatocyte growth factor.
Proc.Natl.Acad.Sci.USA, 107, 2010
3LH0
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BU of 3lh0 by Molmil
Crystal structure of the 53BP1 tandem tudor domain in complex with p53K372me2
Descriptor: DIMETHYLATED p53 LYSINE 372 PEPTIDE, SULFATE ION, TRIETHYLENE GLYCOL, ...
Authors:Roy, S, Kutateladze, T.G.
Deposit date:2010-01-21
Release date:2010-03-23
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural insight into p53 recognition by the 53BP1 tandem Tudor domain.
J.Mol.Biol., 398, 2010
3LLO
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BU of 3llo by Molmil
Crystal structure of the STAS domain of motor protein prestin (anion transporter SLC26A5)
Descriptor: Prestin, octyl beta-D-glucopyranoside
Authors:Pasqualetto, E, Aiello, R, Bonetto, G, Battistutta, R.
Deposit date:2010-01-29
Release date:2010-05-26
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.57 Å)
Cite:Structure of the cytosolic portion of the motor protein prestin and functional role of the STAS domain in SLC26/SulP anion transporters.
J.Mol.Biol., 400, 2010
3LHC
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BU of 3lhc by Molmil
Crystal structure of cyanovirin-n swapping domain b mutant
Descriptor: Cyanovirin-N, PHOSPHATE ION, SODIUM ION
Authors:Matei, E, Zheng, A, Furey, W, Rose, J, Aiken, C, Gronenborn, A.M.
Deposit date:2010-01-21
Release date:2010-02-09
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.34 Å)
Cite:Anti-HIV activity of defective cyanovirin-N mutants is restored by dimerization.
J.Biol.Chem., 285, 2010
3KKO
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BU of 3kko by Molmil
Crystal structure of M-Ras P40D/D41E/L51R in complex with GppNHp
Descriptor: MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, Ras-related protein M-Ras, ...
Authors:Muraoka, S, Shima, F, Liao, J, Ijiri, Y, Matsumoto, K, Ye, M, Inoue, T, Kataoka, T.
Deposit date:2009-11-06
Release date:2010-06-16
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural basis for conformational dynamics of GTP-bound Ras protein
J.Biol.Chem., 285, 2010
3DWH
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BU of 3dwh by Molmil
Structural and Functional Analysis of SRA domain
Descriptor: E3 ubiquitin-protein ligase UHRF1, GLYCEROL, SULFATE ION
Authors:Qian, C, Jakoncic, J, Zhou, M.
Deposit date:2008-07-22
Release date:2008-10-21
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Structure and Hemimethylated CpG Binding of the SRA Domain from Human UHRF1.
J.Biol.Chem., 283, 2008
3E07
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BU of 3e07 by Molmil
Crystal structure of spatzle cystine knot
Descriptor: GLYCEROL, Protein spaetzle
Authors:Hoffmann, A, Funkner, A, Neumann, P, Juhnke, S, Walther, M, Schierhorn, A, Weininger, U, Balbach, J, Reuter, G, Stubbs, M.T.
Deposit date:2008-07-31
Release date:2008-09-23
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Biophysical Characterization of Refolded Drosophila Spatzle, a Cystine Knot Protein, Reveals Distinct Properties of Three Isoforms
J.Biol.Chem., 283, 2008
3KO0
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BU of 3ko0 by Molmil
Structure of the tfp-ca2+-bound activated form of the s100a4 Metastasis factor
Descriptor: 10-[3-(4-METHYL-PIPERAZIN-1-YL)-PROPYL]-2-TRIFLUOROMETHYL-10H-PHENOTHIAZINE, CALCIUM ION, Protein S100-A4
Authors:Malashkevich, V.N, Dulyaninova, N.G, Knight, D, Almo, S.C, Bresnick, A.R.
Deposit date:2009-11-12
Release date:2010-05-26
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Phenothiazines inhibit S100A4 function by inducing protein oligomerization.
Proc.Natl.Acad.Sci.USA, 107, 2010
3KVR
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BU of 3kvr by Molmil
Trapping of an oxocarbenium ion intermediate in UP crystals
Descriptor: 2,5-anhydro-4-deoxy-D-erythro-pent-4-enitol, 5-FLUOROURACIL, SULFATE ION, ...
Authors:Paul, D, O'Leary, S, Rajashankar, K, Bu, W, Toms, A, Settembre, E, Sanders, J, Begley, T.P, Ealick, S.E.
Deposit date:2009-11-30
Release date:2010-04-28
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Glycal formation in crystals of uridine phosphorylase.
Biochemistry, 49, 2010
3GMH
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BU of 3gmh by Molmil
Crystal Structure of the Mad2 Dimer
Descriptor: Mitotic spindle assembly checkpoint protein MAD2A, SULFATE ION
Authors:Ozkan, E, Luo, X, Machius, M, Yu, H, Deisenhofer, J.
Deposit date:2009-03-13
Release date:2010-11-17
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (3.95 Å)
Cite:Structure of an intermediate conformer of the spindle checkpoint protein Mad2.
Proc.Natl.Acad.Sci.USA, 112, 2015
3KZD
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BU of 3kzd by Molmil
Crystal Structure of Free T-cell Lymphoma Invasion and Metastasis-1 PDZ Domain
Descriptor: T-lymphoma invasion and metastasis-inducing protein 1
Authors:Shepherd, T.R, Fuentes, E.J.
Deposit date:2009-12-08
Release date:2010-04-21
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:The Tiam1 PDZ domain couples to Syndecan1 and promotes cell-matrix adhesion.
J.Mol.Biol., 398, 2010
3HCM
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BU of 3hcm by Molmil
Crystal structure of human S100B in complex with S45
Descriptor: (3R)-3-[3-(4-chlorophenyl)-1,2,4-oxadiazol-5-yl]piperidine, ACETATE ION, CALCIUM ION, ...
Authors:Mangani, S, Cesari, L.
Deposit date:2009-05-06
Release date:2010-02-02
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2 Å)
Cite:Fragmenting the S100B-p53 Interaction: Combined Virtual/Biophysical Screening Approaches to Identify Ligands
Chemmedchem, 5, 2010
3EVS
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BU of 3evs by Molmil
Crystal structure of the GDF-5:BMP receptor IB complex.
Descriptor: Bone morphogenetic protein receptor type-1B, Growth/differentiation factor 5
Authors:Kotzsch, A, Mueller, T.D.
Deposit date:2008-10-13
Release date:2009-03-10
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal structure analysis reveals a spring-loaded latch as molecular mechanism for GDF-5-type I receptor specificity.
Embo J., 28, 2009
3LI6
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BU of 3li6 by Molmil
Crystal structure and trimer-monomer transition of N-terminal domain of EhCaBP1 from Entamoeba histolytica
Descriptor: CALCIUM ION, Calcium-binding protein
Authors:Kumar, S, Ahmad, E, Kumar, S, Mansuri, M.S, Khan, R.H, Samudrala, G.
Deposit date:2010-01-24
Release date:2010-02-02
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.502 Å)
Cite:Crystal structure and trimer-monomer transition of N-terminal domain of EhCaBP1 from Entamoeba histolytica
Biophys.J., 98, 2010
3LJW
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BU of 3ljw by Molmil
Crystal Structure of the Second Bromodomain of Human Polybromo
Descriptor: ACETATE ION, Protein polybromo-1, SODIUM ION
Authors:Charlop-Powers, Z, Zhou, M.M, Zeng, L, Zhang, Q.
Deposit date:2010-01-26
Release date:2010-05-19
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.501 Å)
Cite:Structural insights into selective histone H3 recognition by the human Polybromo bromodomain 2.
Cell Res., 20, 2010
3F0L
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BU of 3f0l by Molmil
Crystal structure of oxidized D105N Synechocystis sp. PcyA
Descriptor: 1,2-ETHANEDIOL, BILIVERDINE IX ALPHA, Phycocyanobilin:ferredoxin oxidoreductase
Authors:Kohler, A.C, Gae, D.D.
Deposit date:2008-10-25
Release date:2009-10-13
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:Structural basis for hydration dynamics in radical stabilization of bilin reductase mutants.
Biochemistry, 49, 2010
3LB9
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BU of 3lb9 by Molmil
Crystal structure of the B. circulans cpA123 circular permutant
Descriptor: Endo-1,4-beta-xylanase
Authors:D'Angelo, I, Reitinger, S, Ludwiczek, M, Strynadka, N, Withers, S.G, Mcintosh, L.P.
Deposit date:2010-01-08
Release date:2010-03-23
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (3 Å)
Cite:Circular permutation of Bacillus circulans xylanase: a kinetic and structural study.
Biochemistry, 49, 2010
3F2O
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BU of 3f2o by Molmil
Crystal Structure of human splA/ryanodine receptor domain and SOCS box containing 1 (SPSB1) in complex with a 20-residue VASA peptide
Descriptor: 20-mer peptide from ATP-dependent RNA helicase vasa, SPRY domain-containing SOCS box protein 1
Authors:Filippakopoulos, P, Sharpe, T, Keates, T, Murray, J.W, Savitsky, P, Roos, A, Pike, A.C.W, Von Delft, F, Arrowsmith, C.H, Edwards, A.M, Weigelt, J, Bountra, C, Knapp, S, Bullock, A, Structural Genomics Consortium (SGC)
Deposit date:2008-10-30
Release date:2008-12-09
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Structural basis for Par-4 recognition by the SPRY domain- and SOCS box-containing proteins SPSB1, SPSB2, and SPSB4.
J.Mol.Biol., 401, 2010
3KU4
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Trapping of an oxocarbenium ion intermediate in UP crystals
Descriptor: SULFATE ION, Uridine phosphorylase
Authors:Paul, D, O'Leary, S, Rajashankar, K, Bu, W, Toms, A, Settembre, E, Sanders, J, Begley, T.P, Ealick, S.E.
Deposit date:2009-11-26
Release date:2010-04-28
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.099 Å)
Cite:Glycal formation in crystals of uridine phosphorylase.
Biochemistry, 49, 2010

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