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8OMU
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BU of 8omu by Molmil
Cryo-EM structure of rat SLC22A6 bound to alpha-ketoglutaric acid in a low occupancy state
Descriptor: Solute carrier family 22 member 6, Synthetic nanobody (Sybody)
Authors:Parker, J.L, Kato, T, Newstead, S.
Deposit date:2023-03-31
Release date:2023-07-19
Last modified:2023-11-22
Method:ELECTRON MICROSCOPY (3.43 Å)
Cite:Molecular basis for selective uptake and elimination of organic anions in the kidney by OAT1.
Nat.Struct.Mol.Biol., 30, 2023
1G4C
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BU of 1g4c by Molmil
CRYSTAL STRUCTURE OF A COMPLEX OF HPPK(R92A) FROM E.COLI WITH MG2+ AT 1.65 ANGSTROM RESOLUTION
Descriptor: 6-HYDROXYMETHYL-7,8-DIHYDROPTERIN PYROPHOSPHOKINASE, CHLORIDE ION, MAGNESIUM ION
Authors:Blaszczyk, J, Ji, X.
Deposit date:2000-10-26
Release date:2003-04-15
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Dynamic Roles of Arginine Residues 82 and 92 of Escherichia coli 6-Hydroxymethyl-7,8-dihydropterin Pyrophosphokinase: Crystallographic Studies
Biochemistry, 42, 2003
6LPG
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BU of 6lpg by Molmil
human VASH1-SVBP complex
Descriptor: SULFATE ION, Small vasohibin-binding protein, Tubulinyl-Tyr carboxypeptidase 1
Authors:Ikeda, A, Nishino, T.
Deposit date:2020-01-10
Release date:2020-10-21
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:The crystal structure of the tetrameric human vasohibin-1-SVBP complex reveals a variable arm region within the structural core.
Acta Crystallogr D Struct Biol, 76, 2020
6NIT
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BU of 6nit by Molmil
Human Argonaute2-miR-122 bound to a target RNA with four central mismatches (bu4)
Descriptor: Protein argonaute-2, RNA (5'-R(P*AP*AP*CP*AP*CP*CP*AP*UP*CP*CP*AP*AP*CP*AP*CP*UP*CP*CP*AP*AP*A)-3'), RNA (5'-R(P*UP*GP*GP*AP*GP*UP*GP*UP*GP*AP*CP*AP*AP*UP*GP*GP*UP*GP*UP*UP*U)-3')
Authors:Sheu-Gruttadauria, J, MacRae, I.J.
Deposit date:2018-12-31
Release date:2019-08-07
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (3.8 Å)
Cite:Structural Basis for Target-Directed MicroRNA Degradation.
Mol.Cell, 75, 2019
4TNV
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BU of 4tnv by Molmil
C. elegans glutamate-gated chloride channel (GluCl) in complex with Fab in a non-conducting conformation
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Avermectin-sensitive glutamate-gated chloride channel GluCl alpha, CHLORIDE ION, ...
Authors:Althoff, T, Hibbs, R.E, Banerjee, S, Gouaux, E.
Deposit date:2014-06-05
Release date:2014-08-13
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (3.6 Å)
Cite:X-ray structures of GluCl in apo states reveal a gating mechanism of Cys-loop receptors.
Nature, 512, 2014
7DS8
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BU of 7ds8 by Molmil
Crystal structure of actin capping protein in complex with twinflin-1/CD2AP CPI chimera peptide (CDN-TWC)
Descriptor: CD2-associated protein,Twinfilin-1, F-actin-capping protein subunit alpha-1, F-actin-capping protein subunit beta isoforms 1
Authors:Takeda, S.
Deposit date:2020-12-30
Release date:2021-03-03
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Structural Insights into the Regulation of Actin Capping Protein by Twinfilin C-terminal Tail.
J.Mol.Biol., 433, 2021
7DS4
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BU of 7ds4 by Molmil
Crystal structure of actin capping protein in complex with twinflin-1 C-terminus tail F323K mutant
Descriptor: F-actin-capping protein subunit alpha-1, F-actin-capping protein subunit beta isoforms 1, Twinfilin-1
Authors:Takeda, S.
Deposit date:2020-12-30
Release date:2021-03-03
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Structural Insights into the Regulation of Actin Capping Protein by Twinfilin C-terminal Tail.
J.Mol.Biol., 433, 2021
7DS3
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BU of 7ds3 by Molmil
Crystal structure of actin capping protein in complex with twinflin-2 C-terminus tail
Descriptor: F-actin-capping protein subunit alpha-1, F-actin-capping protein subunit beta isoforms 1, Twinfilin-2
Authors:Takeda, S.
Deposit date:2020-12-30
Release date:2021-03-03
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.09 Å)
Cite:Structural Insights into the Regulation of Actin Capping Protein by Twinfilin C-terminal Tail.
J.Mol.Biol., 433, 2021
7DS6
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BU of 7ds6 by Molmil
Crystal structure of actin capping protein in complex with twinflin-1/CD2AP CPI chimera peptide (TWN-CDC)
Descriptor: F-actin-capping protein subunit alpha-1, F-actin-capping protein subunit beta isoforms 1, Twinfilin-1,CD2-associated protein
Authors:Takeda, S.
Deposit date:2020-12-30
Release date:2021-03-03
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.69 Å)
Cite:Structural Insights into the Regulation of Actin Capping Protein by Twinfilin C-terminal Tail.
J.Mol.Biol., 433, 2021
7DS2
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BU of 7ds2 by Molmil
Crystal structure of actin capping protein in complex with twinflin-1 C-terminus tail
Descriptor: F-actin-capping protein subunit alpha-1, F-actin-capping protein subunit beta isoforms 1, Twinfilin-1
Authors:Takeda, S.
Deposit date:2020-12-30
Release date:2021-03-03
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Structural Insights into the Regulation of Actin Capping Protein by Twinfilin C-terminal Tail.
J.Mol.Biol., 433, 2021
7DSB
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BU of 7dsb by Molmil
Crystal structure of actin capping protein in complex with V-1 and twinfilin C-terminal tail
Descriptor: F-actin-capping protein subunit alpha-1, F-actin-capping protein subunit beta isoforms 1, Myotrophin, ...
Authors:Takeda, S.
Deposit date:2020-12-30
Release date:2021-03-03
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.44 Å)
Cite:Structural Insights into the Regulation of Actin Capping Protein by Twinfilin C-terminal Tail.
J.Mol.Biol., 433, 2021
7DA0
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BU of 7da0 by Molmil
High-resolution crystal structure of the chicken MHF complex
Descriptor: Centromere protein S, Centromere protein X
Authors:Ito, S, Nishino, T.
Deposit date:2020-10-14
Release date:2021-03-17
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.25 Å)
Cite:Structural analysis of the chicken FANCM-MHF complex and its stability.
Acta Crystallogr.,Sect.F, 77, 2021
7DA1
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BU of 7da1 by Molmil
Crystal structure of the chicken MHF complex
Descriptor: Centromere protein S, Centromere protein X
Authors:Ito, S, Nishino, T.
Deposit date:2020-10-14
Release date:2021-03-17
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.01 Å)
Cite:Structural analysis of the chicken FANCM-MHF complex and its stability.
Acta Crystallogr.,Sect.F, 77, 2021
7DA2
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BU of 7da2 by Molmil
The crystal structure of the chicken FANCM-MHF complex
Descriptor: Centromere protein S, Centromere protein X, Fanconi anemia group M protein
Authors:Nishino, T, Ito, S.
Deposit date:2020-10-14
Release date:2021-03-17
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.79 Å)
Cite:Structural analysis of the chicken FANCM-MHF complex and its stability.
Acta Crystallogr.,Sect.F, 77, 2021
3HW1
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BU of 3hw1 by Molmil
Structure of Bace (beta secretase) in complex with ligand EV2
Descriptor: 3-pyrrolidin-1-ylquinoxalin-2-amine, Beta-secretase 1, GLYCEROL
Authors:Godemann, R, Madden, J, Kramer, J, Smith, M.A, Barker, J, Ebneth, A.
Deposit date:2009-06-17
Release date:2009-11-03
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.48 Å)
Cite:Fragment-Based Discovery of BACE1 Inhibitors Using Functional Assays
Biochemistry, 48, 2009
7BK4
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BU of 7bk4 by Molmil
Crystal structure of RXRalpha ligand binding domain in complex with a fragment of the TIF2 coactivator
Descriptor: 6-[1-(3,5,5,8,8-PENTAMETHYL-5,6,7,8-TETRAHYDRONAPHTHALEN-2-YL)CYCLOPROPYL]PYRIDINE-3-CARBOXYLIC ACID, Nuclear receptor coactivator 2, Retinoic acid receptor RXR-alpha
Authors:le Maire, A, Bourguet, W.
Deposit date:2021-01-15
Release date:2021-08-04
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural Insights into the Interaction of the Intrinsically Disordered Co-activator TIF2 with Retinoic Acid Receptor Heterodimer (RXR/RAR).
J.Mol.Biol., 433, 2021
7K5L
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BU of 7k5l by Molmil
Ebola virus VP40 octameric ring generated by an RNA oligonucleotide
Descriptor: HSP RNA oligonucleotide, Matrix protein VP40
Authors:Landeras-Bueno, S, Wasserman, H, Salie, Z.L, Saphire, E.O.
Deposit date:2020-09-17
Release date:2021-04-21
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.38 Å)
Cite:Cellular mRNA triggers structural transformation of Ebola virus matrix protein VP40 to its essential regulatory form.
Cell Rep, 35, 2021
7K5D
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BU of 7k5d by Molmil
Ebola virus VP40 octameric ring generated by a DNA oligonucleotide
Descriptor: HSP DNA oligonucleotide, Matrix protein VP40
Authors:Landeras-Bueno, S, Wasserman, H, Salie, Z.L, Saphire, E.O.
Deposit date:2020-09-16
Release date:2021-04-21
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.78 Å)
Cite:Cellular mRNA triggers structural transformation of Ebola virus matrix protein VP40 to its essential regulatory form.
Cell Rep, 35, 2021
3LW8
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BU of 3lw8 by Molmil
Shigella IpgB2 in complex with human RhoA, GDP and Mg2+ (complex A)
Descriptor: GUANOSINE-5'-DIPHOSPHATE, IpgB2, MAGNESIUM ION, ...
Authors:Klink, B.U, Barden, S, Heidler, T.V, Borchers, C, Ladwein, M, Stradal, T.E.B, Rottner, K, Heinz, D.W.
Deposit date:2010-02-23
Release date:2010-03-31
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Structure of Shigella IPGB2 in complex with human RhoA: Implications for the mechanism of bacterial GEF-mimicry
J.Biol.Chem., 285, 2010
7JV3
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BU of 7jv3 by Molmil
Crystal structure of alkanesulfonate monooxygenase MsuD from Pseudomonas fluorescens
Descriptor: Alkanesulfonate monooxygenase
Authors:Liew, J.J.M, Dowling, D.P.
Deposit date:2020-08-20
Release date:2021-05-26
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structures of the alkanesulfonate monooxygenase MsuD provide insight into C-S bond cleavage, substrate scope, and an unexpected role for the tetramer.
J.Biol.Chem., 297, 2021
7BED
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BU of 7bed by Molmil
X-ray structure of WDR5 bound to the WDR5 win motif peptide
Descriptor: SULFATE ION, WD repeat-containing protein 5
Authors:McVey, C.E, Kaye, K.M.
Deposit date:2020-12-23
Release date:2021-12-08
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.26 Å)
Cite:MLL1 is regulated by KSHV LANA and is important for virus latency.
Nucleic Acids Res., 49, 2021
4PEP
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BU of 4pep by Molmil
THE MOLECULAR AND CRYSTAL STRUCTURES OF MONOCLINIC PORCINE PEPSIN REFINED AT 1.8 ANGSTROMS RESOLUTION
Descriptor: PEPSIN
Authors:Andreeva, N, Fedorov, A.A, Sielecki, A, James, M.
Deposit date:1989-12-18
Release date:1990-04-15
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Molecular and crystal structures of monoclinic porcine pepsin refined at 1.8 A resolution.
J.Mol.Biol., 214, 1990
2CND
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BU of 2cnd by Molmil
STRUCTURAL STUDIES ON CORN NITRATE REDUCTASE: REFINED STRUCTURE OF THE CYTOCHROME B REDUCTASE FRAGMENT AT 2.5 ANGSTROMS, ITS ADP COMPLEX AND AN ACTIVE SITE MUTANT AND MODELING OF THE CYTOCHROME B DOMAIN
Descriptor: FLAVIN-ADENINE DINUCLEOTIDE, NADH-DEPENDENT NITRATE REDUCTASE
Authors:Lu, G, Lindqvist, Y, Schneider, G.
Deposit date:1995-02-01
Release date:1995-04-20
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural studies on corn nitrate reductase: refined structure of the cytochrome b reductase fragment at 2.5 A, its ADP complex and an active-site mutant and modeling of the cytochrome b domain.
J.Mol.Biol., 248, 1995
7JSD
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BU of 7jsd by Molmil
Hydroxylase homolog of BesD with Fe(II), alpha-ketoglutarate, and lysine
Descriptor: 2-OXOGLUTARIC ACID, FE (II) ION, LYSINE, ...
Authors:Kissman, E.N, Neugebauer, M.E, Chang, M.C.Y.
Deposit date:2020-08-14
Release date:2021-08-25
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Reaction pathway engineering converts a radical hydroxylase into a halogenase.
Nat.Chem.Biol., 18, 2022
7JUA
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BU of 7jua by Molmil
Crystal structure of the second heterocyclization domain of yersiniabactin synthetase at 2.35 A resolution
Descriptor: 2-(2-METHOXYETHOXY)ETHANOL, Irp2 protein, SODIUM ION
Authors:Xia, Y, Soule, J, Dowling, D.P.
Deposit date:2020-08-19
Release date:2021-09-22
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:High-resolution structures of a siderophore-producing cyclization domain from Yersinia pestis offer a refined proposal of substrate binding.
J.Biol.Chem., 2022

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PDB entries from 2024-10-16

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