7BK4
Crystal structure of RXRalpha ligand binding domain in complex with a fragment of the TIF2 coactivator
Summary for 7BK4
Entry DOI | 10.2210/pdb7bk4/pdb |
Descriptor | Retinoic acid receptor RXR-alpha, Nuclear receptor coactivator 2, 6-[1-(3,5,5,8,8-PENTAMETHYL-5,6,7,8-TETRAHYDRONAPHTHALEN-2-YL)CYCLOPROPYL]PYRIDINE-3-CARBOXYLIC ACID, ... (4 entities in total) |
Functional Keywords | nuclear receptor, ligand binding domain, coactivator, transcription |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 4 |
Total formula weight | 61395.13 |
Authors | le Maire, A.,Bourguet, W. (deposition date: 2021-01-15, release date: 2021-08-04, Last modification date: 2024-01-31) |
Primary citation | Senicourt, L.,le Maire, A.,Allemand, F.,Carvalho, J.E.,Guee, L.,Germain, P.,Schubert, M.,Bernado, P.,Bourguet, W.,Sibille, N. Structural Insights into the Interaction of the Intrinsically Disordered Co-activator TIF2 with Retinoic Acid Receptor Heterodimer (RXR/RAR). J.Mol.Biol., 433:166899-166899, 2021 Cited by PubMed: 33647291DOI: 10.1016/j.jmb.2021.166899 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.8 Å) |
Structure validation
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