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6QCG
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PCNA complex with Cdt1 N-terminal PIP-box peptide
Descriptor: DNA replication factor Cdt1, Proliferating cell nuclear antigen
Authors:Perrakis, A, von Castelmur, E.
Deposit date:2018-12-28
Release date:2019-01-23
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:Direct binding of Cdt2 to PCNA is important for targeting the CRL4Cdt2E3 ligase activity to Cdt1.
Life Sci Alliance, 1, 2018
6QH1
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BU of 6qh1 by Molmil
The structure of Schizosaccharomyces pombe PCNA in complex with an Spd1 derived peptide
Descriptor: Proliferating cell nuclear antigen, S-phase delaying protein 1
Authors:Kragelund, B.B, Nielsen, O, Olsen, J.G, Kassem, N, Prestel, A.
Deposit date:2019-01-14
Release date:2020-02-05
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:The structure of Schizosaccharomyces pombe PCNA in complex with an Spd1 derived peptide
To Be Published
5E0U
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Human PCNA variant (S228I) complexed with p21 at 1.9 Angstroms
Descriptor: Cyclin-dependent kinase inhibitor 1, Proliferating cell nuclear antigen
Authors:Duffy, C.M, Hilbert, B.J, Kelch, B.A.
Deposit date:2015-09-29
Release date:2016-04-20
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.93 Å)
Cite:A Disease-Causing Variant in PCNA Disrupts a Promiscuous Protein Binding Site.
J.Mol.Biol., 428, 2016
5E0V
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Human PCNA variant (S228I) complexed with FEN1 at 2.1 Angstroms
Descriptor: Flap endonuclease 1, Proliferating cell nuclear antigen
Authors:Duffy, C.M, Hilbert, B.J, Kelch, B.A.
Deposit date:2015-09-29
Release date:2016-04-20
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.074 Å)
Cite:A Disease-Causing Variant in PCNA Disrupts a Promiscuous Protein Binding Site.
J.Mol.Biol., 428, 2016
5E0T
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Human PCNA mutant - S228I
Descriptor: Proliferating cell nuclear antigen
Authors:Duffy, C.M, Hilbert, B.J, Kelch, B.A.
Deposit date:2015-09-29
Release date:2016-04-20
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.6653 Å)
Cite:A Disease-Causing Variant in PCNA Disrupts a Promiscuous Protein Binding Site.
J.Mol.Biol., 428, 2016
1UL1
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BU of 1ul1 by Molmil
Crystal structure of the human FEN1-PCNA complex
Descriptor: Flap endonuclease-1, MAGNESIUM ION, Proliferating cell nuclear antigen
Authors:Sakurai, S, Kitano, K, Yamaguchi, H, Hamada, K, Okada, K, Fukuda, K, Uchida, M, Ohtsuka, E, Morioka, H, Hakoshima, T.
Deposit date:2003-09-05
Release date:2005-03-01
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structural basis for recruitment of human flap endonuclease 1 to PCNA
EMBO J., 24, 2005
1U76
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Crystal structure of hPCNA bound to residues 452-466 of the DNA polymerase-delta-p66 subunit
Descriptor: KANRQVSITGFFQRK peptide from DNA polymerase delta subunit 3, Proliferating cell nuclear antigen
Authors:Bruning, J.B, Shamoo, Y.
Deposit date:2004-08-02
Release date:2004-12-14
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural and Thermodynamic Analysis of Human PCNA with Peptides Derived from DNA Polymerase-delta p66 Subunit and Flap Endonuclease-1.
Structure, 12, 2004
7M5M
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PCNA bound to peptide mimetic
Descriptor: N-BUTANE, Peptide mimetic (ACE)RQCSMTCFYHSK(NH2) with linker, Proliferating cell nuclear antigen
Authors:Vandborg, B.A, Bruning, J.B.
Deposit date:2021-03-24
Release date:2021-08-11
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (3 Å)
Cite:A cell permeable bimane-constrained PCNA-interacting peptide.
Rsc Chem Biol, 2, 2021
7M5L
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PCNA bound to peptide mimetic with linker
Descriptor: PROPANE, Peptide mimetic (ACE)RQCSMTCFYHSK(NH2) with linker, Proliferating cell nuclear antigen
Authors:Vandborg, B.A, Bruning, J.B.
Deposit date:2021-03-24
Release date:2021-08-11
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (3 Å)
Cite:A cell permeable bimane-constrained PCNA-interacting peptide.
Rsc Chem Biol, 2, 2021
7M5N
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PCNA bound to peptide mimetic with linker
Descriptor: 1,3-dimethylbenzene, Peptide mimetic (ACE)RQCSMTCFYHSK(NH2) with linker, Proliferating cell nuclear antigen
Authors:Vandborg, B.A, Bruning, J.B.
Deposit date:2021-03-24
Release date:2021-08-11
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (3.11 Å)
Cite:A cell permeable bimane-constrained PCNA-interacting peptide.
Rsc Chem Biol, 2, 2021
7N5K
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PCNA from Thermococcus gammatolerans: crystal II, collection 1, 1.98 A, 3.84 MGy
Descriptor: DNA polymerase sliding clamp, GLYCEROL, SULFATE ION
Authors:Marin-Tovar, Y, Rudino-Pinera, E.
Deposit date:2021-06-05
Release date:2022-05-04
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.98 Å)
Cite:PCNA from Thermococcus gammatolerans: A protein involved in chromosomal DNA metabolism intrinsically resistant at high levels of ionizing radiation.
Proteins, 90, 2022
7N5M
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PCNA from Thermococcus gammatolerans: crystal III, collection 1, 2.00 A, 1.91 MGy
Descriptor: DNA polymerase sliding clamp, GLYCEROL, SULFATE ION
Authors:Marin-Tovar, Y, Rudino-Pinera, E.
Deposit date:2021-06-05
Release date:2022-05-04
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2 Å)
Cite:PCNA from Thermococcus gammatolerans: A protein involved in chromosomal DNA metabolism intrinsically resistant at high levels of ionizing radiation.
Proteins, 90, 2022
7N5I
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PCNA from Thermococcus gammatolerans: crystal I, collection 1, 1.95 A, 5.22 MGy
Descriptor: DNA polymerase sliding clamp, GLYCEROL, SULFATE ION
Authors:Marin-Tovar, Y, Rudino-Pinera, E.
Deposit date:2021-06-05
Release date:2022-05-04
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:PCNA from Thermococcus gammatolerans: A protein involved in chromosomal DNA metabolism intrinsically resistant at high levels of ionizing radiation.
Proteins, 90, 2022
7N5N
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PCNA from Thermococcus gammatolerans: crystal III, collection 15, 2.20 A, 28.7 MGy
Descriptor: DNA polymerase sliding clamp, GLYCEROL, SULFATE ION
Authors:Marin-Tovar, Y, Rudino-Pinera, E.
Deposit date:2021-06-05
Release date:2022-05-04
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:PCNA from Thermococcus gammatolerans: A protein involved in chromosomal DNA metabolism intrinsically resistant at high levels of ionizing radiation.
Proteins, 90, 2022
7N5J
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PCNA from Thermococcus gammatolerans: crystal I, collection 5, 2.82 A, 89.1 MGy
Descriptor: DNA polymerase sliding clamp, GLYCEROL, SULFATE ION
Authors:Marin-Tovar, Y, Rudino-Pinera, E.
Deposit date:2021-06-05
Release date:2022-05-04
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.82 Å)
Cite:PCNA from Thermococcus gammatolerans: A protein involved in chromosomal DNA metabolism intrinsically resistant at high levels of ionizing radiation.
Proteins, 90, 2022
7N5L
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BU of 7n5l by Molmil
PCNA from Thermococcus gammatolerans: crystal II, collection 20, 3.07 A, 77.0 MGy
Descriptor: DNA polymerase sliding clamp, GLYCEROL, SULFATE ION
Authors:Marin-Tovar, Y, Rudino-Pinera, E.
Deposit date:2021-06-05
Release date:2022-05-04
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (3.07 Å)
Cite:PCNA from Thermococcus gammatolerans: A protein involved in chromosomal DNA metabolism intrinsically resistant at high levels of ionizing radiation.
Proteins, 90, 2022
8E84
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BU of 8e84 by Molmil
Human PCNA mutant- C148S
Descriptor: Proliferating cell nuclear antigen
Authors:Magrino, J, Page, B, Gaubitz, C, Kelch, B.A.
Deposit date:2022-08-25
Release date:2023-04-12
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:A thermosensitive PCNA allele underlies an ataxia-telangiectasia-like disorder.
J.Biol.Chem., 299, 2023
8F5Q
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BU of 8f5q by Molmil
Crystal structure of human PCNA in complex with the PIP box of FBH1
Descriptor: F-box DNA helicase 1, Proliferating cell nuclear antigen
Authors:Liu, J, Chaves-Arquero, B, Wei, P, Tencer, H, Zhang, G, Blanco, F, Kutateladze, T.
Deposit date:2022-11-15
Release date:2023-09-27
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Molecular insight into the PCNA-binding mode of FBH1.
Structure, 31, 2023
5JNE
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BU of 5jne by Molmil
E2-SUMO-Siz1 E3-SUMO-PCNA complex
Descriptor: E3 SUMO-protein ligase SIZ1,Ubiquitin-like protein SMT3, GLYCEROL, Proliferating cell nuclear antigen, ...
Authors:Lima, C.D, Streich Jr, F.C.
Deposit date:2016-04-29
Release date:2016-08-10
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:Capturing a substrate in an activated RING E3/E2-SUMO complex.
Nature, 536, 2016
3A2F
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BU of 3a2f by Molmil
Crystal Structure of Pyrococcus furiosus DNA polymerase/PCNA monomer mutant complex
Descriptor: DNA polymerase, DNA polymerase sliding clamp
Authors:Nishida, H, Ishino, Y, Morikawa, K.
Deposit date:2009-05-15
Release date:2009-11-03
Last modified:2021-11-10
Method:X-RAY DIFFRACTION (2.67 Å)
Cite:Structural determinant for switching between the polymerase and exonuclease modes in the PCNA-replicative DNA polymerase complex
To be Published
6TNZ
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BU of 6tnz by Molmil
Human polymerase delta-FEN1-PCNA toolbelt
Descriptor: DNA polymerase delta catalytic subunit, DNA polymerase delta subunit 2, DNA polymerase delta subunit 3, ...
Authors:Lancey, C, Hamdan, S.M, De Biasio, A.
Deposit date:2019-12-10
Release date:2019-12-18
Last modified:2024-05-22
Method:ELECTRON MICROSCOPY (4.05 Å)
Cite:Structure of the processive human Pol delta holoenzyme.
Nat Commun, 11, 2020
7KC0
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BU of 7kc0 by Molmil
Structure of the Saccharomyces cerevisiae replicative polymerase delta in complex with a primer/template and the PCNA clamp
Descriptor: 2',3'-DIDEOXY-THYMIDINE-5'-TRIPHOSPHATE, DNA (25-MER), DNA (5'-D(P*AP*TP*GP*AP*CP*CP*AP*TP*GP*AP*TP*TP*AP*CP*GP*AP*AP*TP*TP*GP*C)-3'), ...
Authors:Zheng, F, Georgescu, R, Li, H, O'Donnell, M.E.
Deposit date:2020-10-04
Release date:2020-12-02
Last modified:2020-12-16
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Structure of eukaryotic DNA polymerase delta bound to the PCNA clamp while encircling DNA.
Proc.Natl.Acad.Sci.USA, 117, 2020
6TNY
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BU of 6tny by Molmil
Processive human polymerase delta holoenzyme
Descriptor: DNA polymerase delta catalytic subunit, DNA polymerase delta subunit 2, DNA polymerase delta subunit 3, ...
Authors:Lancey, C, Hamdan, S.M, De Biasio, A.
Deposit date:2019-12-10
Release date:2019-12-18
Last modified:2024-05-22
Method:ELECTRON MICROSCOPY (3.08 Å)
Cite:Structure of the processive human Pol delta holoenzyme.
Nat Commun, 11, 2020
8PPV
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BU of 8ppv by Molmil
Intermediate conformer of Pyrococcus abyssi DNA polymerase D (PolD) bound to a primer/template substrate containing three consecutive mismatches
Descriptor: DNA (5'-D(*P*CP*CP*GP*GP*GP*CP*CP*GP*AP*GP*CP*CP*GP*TP*(GS)P*(G7P)P*(PST)P*(PST)P*(PST))-3'), DNA (5'-D(P*AP*GP*CP*AP*CP*GP*GP*CP*TP*CP*GP*GP*CP*CP*CP*GP*G)-3'), DNA polymerase II small subunit, ...
Authors:Betancurt-Anzola, L, Martinez-Carranza, M, Zatopek, K.M, Gardner, A.F, Sauguet, L.
Deposit date:2023-07-10
Release date:2023-12-20
Last modified:2023-12-27
Method:ELECTRON MICROSCOPY (3.02 Å)
Cite:Molecular basis for proofreading by the unique exonuclease domain of Family-D DNA polymerases.
Nat Commun, 14, 2023
8PPU
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Pyrococcus abyssi DNA polymerase D (PolD) in its editing mode bound to a primer/template substrate containing three consecutive mismatches
Descriptor: DNA (5'-D(P*AP*GP*CP*AP*CP*GP*GP*CP*TP*CP*GP*GP*CP*CP*CP*GP*G)-3'), DNA (5'-D(P*CP*CP*GP*GP*GP*CP*CP*GP*AP*GP*CP*CP*GP*TP*(GS)P*(C7R)P*(PST)P*(PST)P*(PST))-3'), DNA polymerase II small subunit, ...
Authors:Betancurt-Anzola, L, Martinez-Carranza, M, Zatopek, K.M, Gardner, A.F, Sauguet, L.
Deposit date:2023-07-10
Release date:2023-12-20
Last modified:2023-12-27
Method:ELECTRON MICROSCOPY (3.02 Å)
Cite:Molecular basis for proofreading by the unique exonuclease domain of Family-D DNA polymerases.
Nat Commun, 14, 2023

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