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5HVH
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BU of 5hvh by Molmil
Crystal Structure of Thrombin-activatable Fibrinolysis Inhibitor in Complex with two Inhibitory Nanobodies
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Carboxypeptidase B2, ...
Authors:Zhou, X, Weeks, S.D, Strelkov, S.V, Declerck, P.J.
Deposit date:2016-01-28
Release date:2016-06-22
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (3 Å)
Cite:Elucidation of the molecular mechanisms of two nanobodies that inhibit thrombin-activatable fibrinolysis inhibitor activation and activated thrombin-activatable fibrinolysis inhibitor activity.
J.Thromb.Haemost., 14, 2016
5HVF
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BU of 5hvf by Molmil
Crystal Structure of Thrombin-activatable Fibrinolysis Inhibitor in Complex with an Inhibitory Nanobody (VHH-i83)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CITRATE ANION, Carboxypeptidase B2, ...
Authors:Zhou, X, Weeks, S.D, Strelkov, S.V, Declerck, P.J.
Deposit date:2016-01-28
Release date:2016-06-22
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:Elucidation of the molecular mechanisms of two nanobodies that inhibit thrombin-activatable fibrinolysis inhibitor activation and activated thrombin-activatable fibrinolysis inhibitor activity.
J.Thromb.Haemost., 14, 2016
3K2K
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BU of 3k2k by Molmil
Crystal structure of putative carboxypeptidase (YP_103406.1) from BURKHOLDERIA MALLEI ATCC 23344 at 2.49 A resolution
Descriptor: CHLORIDE ION, GLYCEROL, putative carboxypeptidase
Authors:Joint Center for Structural Genomics (JCSG)
Deposit date:2009-09-30
Release date:2009-11-03
Last modified:2023-02-01
Method:X-RAY DIFFRACTION (2.49 Å)
Cite:Crystal structure of putative carboxypeptidase (YP_103406.1) from BURKHOLDERIA MALLEI ATCC 23344 at 2.49 A resolution
To be published
3L2N
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BU of 3l2n by Molmil
Crystal structure of Putative carboxypeptidase A (YP_562911.1) from SHEWANELLA DENITRIFICANS OS-217 at 2.39 A resolution
Descriptor: ACETATE ION, CALCIUM ION, GLYCEROL, ...
Authors:Joint Center for Structural Genomics (JCSG)
Deposit date:2009-12-15
Release date:2009-12-29
Last modified:2023-02-01
Method:X-RAY DIFFRACTION (2.39 Å)
Cite:Crystal structure of Putative carboxypeptidase A (YP_562911.1) from SHEWANELLA DENITRIFICANS OS-217 at 2.39 A resolution
To be published
1AYE
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BU of 1aye by Molmil
HUMAN PROCARBOXYPEPTIDASE A2
Descriptor: PROCARBOXYPEPTIDASE A2, ZINC ION
Authors:Garcia-Saez, I, Reverte, D, Vendrell, J, Aviles, F.X, Coll, M.
Deposit date:1997-11-03
Release date:1999-01-13
Last modified:2023-08-02
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:The three-dimensional structure of human procarboxypeptidase A2. Deciphering the basis of the inhibition, activation and intrinsic activity of the zymogen.
EMBO J., 16, 1997
1ZLI
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BU of 1zli by Molmil
Crystal structure of the tick carboxypeptidase inhibitor in complex with human carboxypeptidase B
Descriptor: Carboxypeptidase B, ZINC ION, carboxypeptidase inhibitor
Authors:Arolas, J.L, Popowicz, G.M, Lorenzo, J, Sommerhoff, C.P, Huber, R, Aviles, F.X, Holak, T.A.
Deposit date:2005-05-06
Release date:2005-07-05
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (2.09 Å)
Cite:The Three-Dimensional Structures of Tick Carboxypeptidase Inhibitor in Complex with A/B Carboxypeptidases Reveal a Novel Double-headed Binding Mode
J.Mol.Biol., 350, 2005
1ZLH
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BU of 1zlh by Molmil
Crystal structure of the tick carboxypeptidase inhibitor in complex with bovine carboxypeptidase A
Descriptor: Carboxypeptidase A1, ZINC ION, carboxypeptidase inhibitor
Authors:Arolas, J.L, Popowicz, G.M, Lorenzo, J, Sommerhoff, C.P, Huber, R, Aviles, F.X, Holak, T.A.
Deposit date:2005-05-06
Release date:2005-07-05
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:The Three-Dimensional Structures of Tick Carboxypeptidase Inhibitor in Complex with A/B Carboxypeptidases Reveal a Novel Double-headed Binding Mode
J.Mol.Biol., 350, 2005
3FJU
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BU of 3fju by Molmil
Ascaris suum carboxypeptidase inhibitor in complex with human carboxypeptidase A1
Descriptor: ACETATE ION, CACODYLATE ION, Carboxypeptidase A inhibitor, ...
Authors:Sanglas, L, Aviles, F.X, Huber, R, Gomis-Ruth, F.X, Arolas, J.L.
Deposit date:2008-12-15
Release date:2008-12-30
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Mammalian metallopeptidase inhibition at the defense barrier of Ascaris parasite
Proc.Natl.Acad.Sci.USA, 106, 2009
3D4U
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BU of 3d4u by Molmil
Bovine thrombin-activatable fibrinolysis inhibitor (TAFIa) in complex with tick-derived carboxypeptidase inhibitor.
Descriptor: ACETATE ION, Carboxypeptidase B2, Carboxypeptidase inhibitor, ...
Authors:Sanglas, L, Valnickova, Z, Arolas, J.L, Pallares, I, Guevara, T, Sola, M, Kristensen, T, Enghild, J.J, Aviles, F.X, Gomis-Ruth, F.X.
Deposit date:2008-05-15
Release date:2008-08-19
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structure of activated thrombin-activatable fibrinolysis inhibitor, a molecular link between coagulation and fibrinolysis.
Mol.Cell, 31, 2008
3D67
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BU of 3d67 by Molmil
Crystal structure of Thrombin-Activatable Fibrinolysis Inhibitor (TAFI) in complex with 2-guanidino-ethyl-mercaptosuccinic acid (GEMSA)
Descriptor: (2-GUANIDINOETHYLMERCAPTO)SUCCINIC ACID, 2-acetamido-2-deoxy-beta-D-glucopyranose, Carboxypeptidase B2, ...
Authors:Brondijk, T.H.C, Huizinga, E.G.
Deposit date:2008-05-19
Release date:2008-07-01
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:Crystal structures of TAFI elucidate the inactivation mechanism of activated TAFI: a novel mechanism for enzyme autoregulation
Blood, 112, 2008
3D66
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BU of 3d66 by Molmil
Crystal structure of Thrombin-Activatable Fibrinolysis Inhibitor (TAFI)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Carboxypeptidase B2, ZINC ION
Authors:Brondijk, T.H.C, Huizinga, E.G.
Deposit date:2008-05-19
Release date:2008-07-01
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Crystal structures of TAFI elucidate the inactivation mechanism of activated TAFI: a novel mechanism for enzyme autoregulation
Blood, 112, 2008
3DGV
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BU of 3dgv by Molmil
Crystal structure of thrombin activatable fibrinolysis inhibitor (TAFI)
Descriptor: 2-acetamido-2-deoxy-alpha-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Anand, K, Pallares, I, Valnickova, Z, Christensen, T, Schreuder, H, Enghild, J.
Deposit date:2008-06-16
Release date:2008-07-22
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:The crystal structure of thrombin-activable fibrinolysis inhibitor (TAFI) provides the structural basis for its intrinsic activity and the short half-life of TAFIa.
J.Biol.Chem., 283, 2008
3GLJ
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BU of 3glj by Molmil
A polymorph of carboxypeptidase B zymogen structure
Descriptor: Carboxypeptidase B, GLYCEROL, ZINC ION
Authors:Fernandez, D.
Deposit date:2009-03-12
Release date:2009-10-20
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.89 Å)
Cite:Analysis of a new crystal form of procarboxypeptidase B: further insights into the catalytic mechanism
Biopolymers, 2009
4A39
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BU of 4a39 by Molmil
Metallo-carboxypeptidase from Pseudomonas Aeruginosa in complex with (2-guanidinoethylmercapto)succinic acid
Descriptor: (2-GUANIDINOETHYLMERCAPTO)SUCCINIC ACID, METALLO-CARBOXYPEPTIDASE, ZINC ION
Authors:Otero, A, Rodriguez de la Vega, M, Tanco, S.M, Lorenzo, J, Aviles, F.X, Reverter, D.
Deposit date:2011-09-30
Release date:2012-05-09
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:The Novel Structure of a Cytosolic M14 Metallocarboxypeptidase (Ccp) from Pseudomonas Aeruginosa: A Model for Mammalian Ccps.
Faseb J., 26, 2012
4A38
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BU of 4a38 by Molmil
METALLO-CARBOXYPEPTIDASE FROM PSEUDOMONAS AUREGINOSA IN COMPLEX WITH L-BENZYLSUCCINIC ACID
Descriptor: L-BENZYLSUCCINIC ACID, METALLO-CARBOXYPEPTIDASE, ZINC ION
Authors:Otero, A, Rodriguez de la Vega, M, Tanco, S.M, Lorenzo, J, Aviles, F.X, Reverter, D.
Deposit date:2011-09-30
Release date:2012-05-09
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2 Å)
Cite:The Novel Structure of a Cytosolic M14 Metallocarboxypeptidase (Ccp) from Pseudomonas Aeruginosa: A Model for Mammalian Ccps.
Faseb J., 26, 2012
4A37
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BU of 4a37 by Molmil
Metallo-carboxypeptidase from Pseudomonas Aeruginosa
Descriptor: METALLO-CARBOXYPEPTIDASE, ZINC ION
Authors:Otero, A, Rodriguez de la Vega, M, Tanco, S.M, Lorenzo, J, Aviles, F.X, Reverter, D.
Deposit date:2011-09-30
Release date:2012-05-09
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:The Novel Structure of a Cytosolic M14 Metallocarboxypeptidase (Ccp) from Pseudomonas Aeruginosa: A Model for Mammalian Ccps.
Faseb J., 26, 2012
1H8L
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BU of 1h8l by Molmil
Duck Carboxypeptidase D Domain II in complex with GEMSA
Descriptor: (2-GUANIDINOETHYLMERCAPTO)SUCCINIC ACID, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Gomis-Rueth, F.X, Coll, M, Aviles, F.X, Vendrell, J, Fricker, L.D.
Deposit date:2001-02-09
Release date:2002-02-08
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:The crystal structure of the inhibitor-complexed carboxypeptidase D domain II and the modeling of regulatory carboxypeptidases.
J. Biol. Chem., 276, 2001
2NSM
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BU of 2nsm by Molmil
Crystal structure of the human carboxypeptidase N (Kininase I) catalytic domain
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Carboxypeptidase N catalytic chain, SULFATE ION
Authors:Keil, C, Maskos, K, Than, M, Hoopes, J.T, Huber, R, Tan, F, Deddish, P.A, Erdoes, E.G, Skidgel, R.A, Bode, W.
Deposit date:2006-11-05
Release date:2007-04-24
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal structure of the human carboxypeptidase N (kininase I) catalytic domain
J.Mol.Biol., 366, 2007
4BD9
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BU of 4bd9 by Molmil
Structure of the complex between SmCI and human carboxypeptidase A4
Descriptor: CARBOXYPEPTIDASE A4, CARBOXYPEPTIDASE INHIBITOR SMCI, ZINC ION
Authors:Alonso-del-Ribero, M, Reytor, M.L, Trejo, S.A, Chavez, M.A, Aviles, F.X, Reverter, D.
Deposit date:2012-10-05
Release date:2013-07-17
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:A Noncanonical Mechanism of Carboxypeptidase Inhibition Revealed by the Crystal Structure of the Tri-Kunitz Smci in Complex with Human Cpa4.
Structure, 21, 2013
1PYT
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BU of 1pyt by Molmil
TERNARY COMPLEX OF PROCARBOXYPEPTIDASE A, PROPROTEINASE E, AND CHYMOTRYPSINOGEN C
Descriptor: CALCIUM ION, CHYMOTRYPSINOGEN C, PROCARBOXYPEPTIDASE A, ...
Authors:Gomis-Ruth, F.X, Gomez, M, Bode, W, Huber, R, Aviles, F.X.
Deposit date:1995-06-21
Release date:1997-01-27
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:The three-dimensional structure of the native ternary complex of bovine pancreatic procarboxypeptidase A with proproteinase E and chymotrypsinogen C.
EMBO J., 14, 1995

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