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3G8F
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Crystal structure of the complex formed between a group II phospholipase A2 and designed peptide inhibitor carbobenzoxy-dehydro-val-ala-arg-ser at 1.2 A resolution
Descriptor: PHQ VAL ALA ARG SER peptide, Phospholipase A2 VRV-PL-VIIIa, SULFATE ION
Authors:Singh, N, Kaur, P, Prem Kumar, R, Somvanshi, R.K, Perbandt, M, Betzel, C, Dey, S, Sharma, S, Singh, T.P.
Deposit date:2009-02-12
Release date:2009-03-10
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.25 Å)
Cite:Crystal Structure of the Complex Formed between a Group II Phospholipase A2 and Designed Peptide Inhibitor Carbobenzoxy-Dehydro-Val-Ala-Arg-Ser at 1.2 A Resolution
To be Published
3I3I
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Crystal Structure of Bothropstoxin-I crystallized at 283 K
Descriptor: Phospholipase A2 homolog bothropstoxin-1
Authors:Salvador, G.H.M, Marchi-Salvador, D.P, Soares, A.M, Fontes, M.R.M.
Deposit date:2009-06-30
Release date:2010-04-28
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.82 Å)
Cite:Comparison between apo and complexed structures of bothropstoxin-I reveals the role of Lys122 and Ca(2+)-binding loop region for the catalytically inactive Lys49-PLA(2)s.
J.Struct.Biol., 171, 2010
3I03
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Crystal structure of bothropstoxin-I chemically modified by p-bromophenacyl bromide (BPB) - monomeric form at a high resolution
Descriptor: ISOPROPYL ALCOHOL, Phospholipase A2 homolog bothropstoxin-1, p-Bromophenacyl bromide
Authors:Marchi-Salvador, D.P, Fernandes, C.A.H, Soares, A.M, Fontes, M.R.M.
Deposit date:2009-06-24
Release date:2010-05-12
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.48 Å)
Cite:Comparison between apo and complexed structures of bothropstoxin-I reveals the role of Lys122 and Ca(2+)-binding loop region for the catalytically inactive Lys49-PLA(2)s.
J.Struct.Biol., 171, 2010
3IQ3
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Crystal Structure of Bothropstoxin-I complexed with polietilene glicol 4000 - crystallized at 283 K
Descriptor: 2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, Phospholipase A2 homolog bothropstoxin-1, SULFATE ION
Authors:Salvador, G.H.M, Marchi-Salvador, D.P, Silva, M.C.O, Soares, A.M, Fontes, M.R.M.
Deposit date:2009-08-19
Release date:2009-10-27
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Comparison between apo and complexed structures of bothropstoxin-I reveals the role of Lys122 and Ca(2+)-binding loop region for the catalytically inactive Lys49-PLA(2)s.
J.Struct.Biol., 171, 2010
3JQL
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Crystal Structure of the Complex Formed Between Phospholipase A2 and a Hexapeptide Fragment of Amyloid Beta Peptide, Lys-Leu-Val-Phe-Phe-Ala at 1.2 A Resolution
Descriptor: Acidic phospholipase A2 3 (Fragment), Amyloid Beta Peptide, CALCIUM ION
Authors:Mirza, Z, Vikram, G, Singh, N, Sinha, M, Sharma, S, Srinivasan, A, Kaur, P, Singh, T.P.
Deposit date:2009-09-07
Release date:2009-09-29
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.2 Å)
Cite:Crystal Structure of the Complex Formed Between Phospholipase A2 and a Hexapeptide Fragment of Amyloid Beta Peptide, Lys-Leu-Val-Phe-Phe-Ala at 1.2 A Resolution
To be Published
3JTI
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Crystal structure of the complex formed between Phospholipase A2 with beta-amyloid fragment, Lys-Gly-Ala-Ile-Ile-Gly-Leu-Met at 1.8 A resolution
Descriptor: CALCIUM ION, Phospholipase A2 isoform 3, octapeptide from Amyloid beta A4 protein
Authors:Pandey, N, Mirza, Z, Vikram, G, Singh, N, Bhushan, A, Kaur, P, Srinivasan, A, Sharma, S, Singh, T.P.
Deposit date:2009-09-12
Release date:2010-07-21
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal structure of the complex formed between Phospholipase A2 with beta-amyloid fragment, Lys-Gly-Ala-Ile-Ile-Gly-Leu-Met at 1.8 A resolution
To be Published
3JQ5
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Phospholipase A2 Prevents the Aggregation of Amyloid Beta Peptides: Crystal Structure of the Complex of Phospholipase A2 with Octapeptide Fragment of Amyloid Beta Peptide, Asp-Ala-Glu-Phe-Arg-His-Asp-Ser at 2 A Resolution
Descriptor: Amyloid Beta Peptide, CALCIUM ION, Phospholipase A2 isoform 3
Authors:Mirza, Z, Vikram, G, Singh, N, Sinha, M, Bhushan, A, Sharma, S, Srinivasan, A, Kaur, P, Singh, T.P.
Deposit date:2009-09-06
Release date:2009-09-29
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.03 Å)
Cite:Phospholipase A2 Prevents the Aggregation of Amyloid Beta Peptides: Crystal Structure of the Complex of Phospholipase A2 with Octapeptide Fragment of Amyloid Beta Peptide, Asp-Ala-Glu-Phe-Arg-His-Asp-Ser at 2 A Resolution
To be Published
3HZD
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Crystal structure of bothropstoxin-I (BthTX-I), a PLA2 homologue from Bothrops jararacussu venom
Descriptor: LITHIUM ION, Phospholipase A2 homolog bothropstoxin-1
Authors:Silva, M.C.O, Marchi-Salvador, D.P, Fernandes, C.A.H, Soares, A.M, Fontes, M.R.M.
Deposit date:2009-06-23
Release date:2009-07-07
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.91 Å)
Cite:Comparison between apo and complexed structures of bothropstoxin-I reveals the role of Lys122 and Ca(2+)-binding loop region for the catalytically inactive Lys49-PLA(2)s.
J.Struct.Biol., 171, 2010
3I3H
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Crystal structure of Bothropstoxin-I crystallized at 291K
Descriptor: Phospholipase A2 homolog bothropstoxin-1
Authors:Salvador, G.H.M, Marchi-Salvador, D.P, Soares, A.M, Fontes, M.R.M.
Deposit date:2009-06-30
Release date:2010-08-11
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.17 Å)
Cite:Structural Studies with a BthTX-I a Lys49 PLA2 from Bothrops jararacussu Snake Venom Crystallized at Different Temperatures
To be Published
3HZW
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Crystal structure of bothropstoxin-I chemically modified by p-bromophenacyl bromide (BPB)
Descriptor: ISOPROPYL ALCOHOL, Phospholipase A2 homolog bothropstoxin-1, p-Bromophenacyl bromide
Authors:Fernandes, C.A.H, Marchi-Salvador, D.P, Soares, A.M, Fontes, M.R.M.
Deposit date:2009-06-24
Release date:2010-05-12
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.28 Å)
Cite:Comparison between apo and complexed structures of bothropstoxin-I reveals the role of Lys122 and Ca(2+)-binding loop region for the catalytically inactive Lys49-PLA(2)s.
J.Struct.Biol., 171, 2010
3JR8
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Crystal Structure of BthTX-II (Asp49-PLA2 from Bothrops jararacussu snake venom) with calcium ions
Descriptor: CALCIUM ION, Phospholipase A2 bothropstoxin-2
Authors:Borges, R.J, dos Santos, J.I, Fontes, M.R.M.
Deposit date:2009-09-08
Release date:2010-09-08
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural, functional, and bioinformatics studies reveal a new snake venom homologue phospholipase A2 class.
Proteins, 79, 2011
3HSW
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Crystal Structure of Porcine Pancreatic Phospholipase A2 in Complex with 2-methoxycyclohexa-2-5-diene-1,4-dione
Descriptor: 2-methoxycyclohexa-2,5-diene-1,4-dione, CALCIUM ION, Phospholipase A2, ...
Authors:Dileep, K.V, Tintu, I, Karthe, P, Mandal, P.K, Haridas, M, Sadasivan, C.
Deposit date:2009-06-11
Release date:2009-06-30
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structure of porcine pancreatic phospholipase A2 in complex with 2-methoxycyclohexa-2-5-diene-1,4-dione
Frontiers in life sci., 2012
3H1X
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Simultaneous inhibition of anti-coagulation and inflammation: Crystal structure of phospholipase A2 complexed with indomethacin at 1.4 A resolution reveals the presence of the new common ligand binding site
Descriptor: INDOMETHACIN, Phospholipase A2 VRV-PL-VIIIa, SULFATE ION
Authors:Singh, N, Prem Kumar, R, Sharma, S, Kaur, P, Singh, T.P.
Deposit date:2009-04-14
Release date:2009-06-09
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Simultaneous inhibition of anti-coagulation and inflammation: crystal structure of phospholipase A2 complexed with indomethacin at 1.4 A resolution reveals the presence of the new common ligand-binding site
J.Mol.Recognit., 22, 2009
3G8G
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Crystal structure of phospholipase A2 ammodytoxin A from vipera ammodytes ammodytes
Descriptor: Phospholipase A2, ammodytoxin A, SULFATE ION
Authors:Saul, F.A, Faure, G.
Deposit date:2009-02-12
Release date:2009-12-15
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Comparative structural studies of two natural isoforms of ammodytoxin, phospholipases A2 from Vipera ammodytes ammodytes which differ in neurotoxicity and anticoagulant activity
J.Struct.Biol., 169, 2010
1A3D
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PHOSPHOLIPASE A2 (PLA2) FROM NAJA NAJA VENOM
Descriptor: PHOSPHOLIPASE A2, SODIUM ION
Authors:Segelke, B.W, Nguyen, D, Chee, R, Xuong, H.N, Dennis, E.A.
Deposit date:1998-01-20
Release date:1998-04-29
Last modified:2023-08-02
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structures of two novel crystal forms of Naja naja naja phospholipase A2 lacking Ca2+ reveal trimeric packing.
J.Mol.Biol., 279, 1998
1A2A
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AGKISTROTOXIN, A PHOSPHOLIPASE A2-TYPE PRESYNAPTIC NEUROTOXIN FROM AGKISTRODON HALYS PALLAS
Descriptor: CHLORIDE ION, PHOSPHOLIPASE A2
Authors:Tang, L, Zhou, Y, Lin, Z.
Deposit date:1997-12-25
Release date:1999-01-13
Last modified:2023-08-02
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal structure of agkistrodotoxin, a phospholipase A2-type presynaptic neurotoxin from agkistrodon halys pallas.
J.Mol.Biol., 282, 1998
1A3F
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PHOSPHOLIPASE A2 (PLA2) FROM NAJA NAJA VENOM
Descriptor: PHOSPHOLIPASE A2
Authors:Segelke, B.W, Nguyen, D, Chee, R, Xuong, H.N, Dennis, E.A.
Deposit date:1998-01-21
Release date:1998-04-29
Last modified:2023-08-02
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Structures of two novel crystal forms of Naja naja naja phospholipase A2 lacking Ca2+ reveal trimeric packing.
J.Mol.Biol., 279, 1998
1AE7
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NOTEXIN, A PRESYNAPTIC NEUROTOXIC PHOSPHOLIPASE A2
Descriptor: PHOSPHOLIPASE A2, SULFATE ION
Authors:Westerlund, B, Nordlund, P, Uhlin, U, Eaker, D, Eklund, H.
Deposit date:1997-03-06
Release date:1997-05-15
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2 Å)
Cite:The three-dimensional structure of notexin, a presynaptic neurotoxic phospholipase A2 at 2.0 A resolution.
FEBS Lett., 301, 1992
1AYP
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A PROBE MOLECULE COMPOSED OF SEVENTEEN PERCENT OF TOTAL DIFFRACTING MATTER GIVES CORRECT SOLUTIONS IN MOLECULAR REPLACEMENT
Descriptor: 1-OCTADECYL-2-ACETAMIDO-2-DEOXY-SN-GLYCEROL-3-PHOSPHOETHYLMETHYL SULFIDE, CALCIUM ION, PHOSPHOLIPASE A2
Authors:Oh, B.-H.
Deposit date:1994-07-19
Release date:1995-07-31
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.57 Å)
Cite:A probe molecule composed of seventeen percent of total diffracting matter gives correct solutions in molecular replacement.
Acta Crystallogr.,Sect.D, 51, 1995
1B4W
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BASIC PHOSPHOLIPASE A2 FROM AGKISTRODON HALYS PALLAS-IMPLICATIONS FOR ITS ASSOCIATION AND ANTICOAGULANT ACTIVITIES BY X-RAY CRYSTALLOGRAPHY
Descriptor: PROTEIN (PHOSPHOLIPASE A2), octyl beta-D-glucopyranoside
Authors:Zhao, K.H, Lin, Z.J.
Deposit date:1998-12-30
Release date:2000-01-12
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structure of basic phospholipase A2 from Agkistrodon halys Pallas: implications for its association, hemolytic and anticoagulant activities.
Toxicon, 38, 2000
1AOK
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VIPOXIN COMPLEX
Descriptor: ACETATE ION, VIPOXIN COMPLEX
Authors:Perbandt, M, Wilson, J.C, Eschenburg, S, Betzel, C.
Deposit date:1997-07-07
Release date:1998-01-21
Last modified:2023-08-02
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structure of vipoxin at 2.0 A: an example of regulation of a toxic function generated by molecular evolution.
FEBS Lett., 412, 1997
1BBC
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STRUCTURE OF RECOMBINANT HUMAN RHEUMATOID ARTHRITIC SYNOVIAL FLUID PHOSPHOLIPASE A2 AT 2.2 ANGSTROMS RESOLUTION
Descriptor: PHOSPHOLIPASE A2
Authors:Wery, J.-P, Schevitz, R.W, Clawson, D.K, Bobbitt, J.L, Dow, E.R, Gamboa, G, Goodsonjunior, T, Hermann, R.B, Kramer, R.M, Mcclure, D.B, Mihelich, E.D, Putnam, J.E, Sharp, J.D, Stark, D.H, Teater, C, Warrick, M.W, Jones, N.D.
Deposit date:1992-05-04
Release date:1993-10-31
Last modified:2019-08-14
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structure of recombinant human rheumatoid arthritic synovial fluid phospholipase A2 at 2.2 A resolution.
Nature, 352, 1991
1BK9
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PHOSPHOLIPASE A2 MODIFIED BY PBPB
Descriptor: 1,4-BUTANEDIOL, CALCIUM ION, PHOSPHOLIPASE A2, ...
Authors:Zhao, H, Tang, L, Wang, X, Lin, Z, Zhou, Y.
Deposit date:1998-07-16
Release date:1999-03-02
Last modified:2023-08-02
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structure of a snake venom phospholipase A2 modified by p-bromo-phenacyl-bromide.
Toxicon, 36, 1998
1BPQ
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PHOSPHOLIPASE A2 ENGINEERING. X-RAY STRUCTURAL AND FUNCTIONAL EVIDENCE FOR THE INTERACTION OF LYSINE-56 WITH SUBSTRATES
Descriptor: CALCIUM ION, PHOSPHOLIPASE A2
Authors:Sundaralingam, M.
Deposit date:1991-10-28
Release date:1993-10-31
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Phospholipase A2 engineering. X-ray structural and functional evidence for the interaction of lysine-56 with substrates.
Biochemistry, 30, 1991
1BVM
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SOLUTION NMR STRUCTURE OF BOVINE PANCREATIC PHOSPHOLIPASE A2, 20 STRUCTURES
Descriptor: PROTEIN (PHOSPHOLIPASE A2)
Authors:Yuan, C.-H, Byeon, I.-J.L, Li, Y, Tsai, M.-D.
Deposit date:1998-09-14
Release date:1999-09-16
Last modified:2023-12-27
Method:SOLUTION NMR
Cite:Structural analysis of phospholipase A2 from functional perspective. 1. Functionally relevant solution structure and roles of the hydrogen-bonding network.
Biochemistry, 38, 1999

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