PDB: 1682 resultsInfo pagesStatus searchChemie searchBIRD

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4N95	E. coli sliding clamp in complex with 5-chloroindoline-2,3-dione Descriptor: 5-chloro-1H-indole-2,3-dione, CALCIUM ION, CHLORIDE ION, ... Authors: Yin, Z, Oakley, A.J. Deposit date: 2013-10-19 Release date: 2013-11-06 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Discovery of lead compounds targeting the bacterial sliding clamp using a fragment-based approach. J.Med.Chem., 57, 2014
6PTR	Crystal structure of a DnaN sliding clamp (DNA polymerase III subunit beta) from Bartonella birtlesii bound to griselimycin Descriptor: 1,2-ETHANEDIOL, ACE-MVA-MP8-NZC-LEU-MP8-LEU-MVA-PRO-MLU-GLY, Beta sliding clamp, ... Authors: Seattle Structural Genomics Center for Infectious Disease (SSGCID) Deposit date: 2019-07-16 Release date: 2019-08-07 Last modified: 2023-11-15 Method: X-RAY DIFFRACTION (1.75 Å) Cite: Crystal structure of a DnaN sliding clamp (DNA polymerase III subunit beta) from Bartonella birtlesii bound to griselimycin To Be Published
6PTV	Crystal structure of a DnaN sliding clamp (DNA polymerase III subunit beta) from Rickettsia rickettsii bound to griselimycin Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, ACE-MVA-MP8-NZC-LEU-MP8-LEU-MVA-PRO-MLU-GLY, Beta sliding clamp Authors: Seattle Structural Genomics Center for Infectious Disease (SSGCID) Deposit date: 2019-07-16 Release date: 2019-08-07 Last modified: 2023-11-15 Method: X-RAY DIFFRACTION (1.85 Å) Cite: Crystal structure of a DnaN sliding clamp (DNA polymerase III subunit beta) from Rickettsia rickettsii bound to griselimycin To Be Published
8DKD	Sliding clamp from M. thermoresistibile Descriptor: Beta sliding clamp Authors: Kapur, M.K, Gray, O.J, Honzatko, R.H, Nelson, S.N. Deposit date: 2022-07-05 Release date: 2023-01-18 Last modified: 2023-10-25 Method: X-RAY DIFFRACTION (3.2 Å) Cite: Interaction of sliding clamp with mycobacterial polymerases To Be Published
5DAI	Proliferating cell nuclear antigen homolog 1 bound to FEN-1 peptide Descriptor: C-terminus of FEN-1 protein, DNA polymerase sliding clamp 1, SULFATE ION Authors: Ladner, J.E, Altieri, A.S, Kelman, Z. Deposit date: 2015-08-20 Release date: 2016-05-11 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (2 Å) Cite: A small protein inhibits proliferating cell nuclear antigen by breaking the DNA clamp. Nucleic Acids Res., 44, 2016
5DA7	monomeric PCNA bound to a small protein inhibitor Descriptor: DNA polymerase sliding clamp 1, Proliferating cell nuclear antigen, SULFATE ION, ... Authors: Ladner, J.E, Altieri, A.S, Kelman, Z. Deposit date: 2015-08-19 Release date: 2016-05-11 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (2.802 Å) Cite: A small protein inhibits proliferating cell nuclear antigen by breaking the DNA clamp. Nucleic Acids Res., 44, 2016
3K4X	Eukaryotic Sliding Clamp PCNA Bound to DNA Descriptor: DNA (5'-D(*CP*CP*CP*AP*TP*CP*GP*TP*AP*T)-3'), DNA (5'-D(*TP*TP*TP*TP*AP*TP*AP*CP*GP*AP*TP*GP*GP*G)-3'), Proliferating cell nuclear antigen Authors: McNally, R, Kuriyan, J. Deposit date: 2009-10-06 Release date: 2010-02-16 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (2.98 Å) Cite: Analysis of the role of PCNA-DNA contacts during clamp loading. Bmc Struct.Biol., 10, 2010
7TIC	Structure of the yeast clamp loader (Replication Factor C RFC) bound to the sliding clamp (Proliferating Cell Nuclear Antigen PCNA) in an autoinhibited conformation Descriptor: ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, ... Authors: Gaubitz, C, Liu, X, Pajak, J, Stone, N, Hayes, J, Demo, G, Kelch, B.A. Deposit date: 2022-01-13 Release date: 2022-02-16 Last modified: 2024-02-28 Method: ELECTRON MICROSCOPY (3.9 Å) Cite: Cryo-EM structures reveal high-resolution mechanism of a DNA polymerase sliding clamp loader. Elife, 11, 2022
7TI8	Structure of the yeast clamp loader (Replication Factor C RFC) bound to the open sliding clamp (Proliferating Cell Nuclear Antigen PCNA) Descriptor: ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, ... Authors: Gaubitz, C, Liu, X, Pajak, J, Stone, N, Hayes, J, Demo, G, Kelch, B.A. Deposit date: 2022-01-13 Release date: 2022-02-16 Last modified: 2024-02-28 Method: ELECTRON MICROSCOPY (3.5 Å) Cite: Cryo-EM structures reveal high-resolution mechanism of a DNA polymerase sliding clamp loader. Elife, 11, 2022
7TIB	Structure of the yeast clamp loader (Replication Factor C RFC) bound to the open sliding clamp (Proliferating Cell Nuclear Antigen PCNA) and primer-template DNA Descriptor: ADENOSINE-5'-DIPHOSPHATE, DNA (5'-D(*AP*GP*AP*CP*AP*CP*TP*AP*CP*GP*AP*GP*TP*AP*CP*AP*TP*A)-3'), DNA (5'-D(P*TP*TP*TP*TP*TP*TP*TP*AP*TP*GP*TP*AP*CP*TP*CP*GP*TP*AP*GP*TP*GP*TP*CP*T)-3'), ... Authors: Gaubitz, C, Liu, X, Pajak, J, Stone, N, Hayes, J, Demo, G, Kelch, B.A. Deposit date: 2022-01-13 Release date: 2022-02-16 Last modified: 2024-02-28 Method: ELECTRON MICROSCOPY (3.4 Å) Cite: Cryo-EM structures reveal high-resolution mechanism of a DNA polymerase sliding clamp loader. Elife, 11, 2022
7THJ	Structure of the yeast clamp loader (Replication Factor C RFC) bound to the sliding clamp (Proliferating Cell Nuclear Antigen PCNA) in an autoinhibited conformation Descriptor: ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, ... Authors: Gaubitz, C, Liu, X, Pajak, J, Stone, N, Hayes, J, Demo, G, Kelch, B.A. Deposit date: 2022-01-11 Release date: 2022-02-16 Last modified: 2024-02-28 Method: ELECTRON MICROSCOPY (3.8 Å) Cite: Cryo-EM structures reveal high-resolution mechanism of a DNA polymerase sliding clamp loader. Elife, 11, 2022
7TID	Structure of the yeast clamp loader (Replication Factor C RFC) bound to the sliding clamp (Proliferating Cell Nuclear Antigen PCNA) and primer-template DNA Descriptor: ADENOSINE-5'-DIPHOSPHATE, DNA (5'-D(*AP*GP*AP*CP*AP*CP*TP*AP*CP*GP*AP*GP*TP*AP*CP*AP*TP*A)-3'), DNA (5'-D(P*TP*TP*TP*TP*TP*TP*TP*AP*TP*GP*TP*AP*CP*TP*CP*GP*TP*AP*GP*TP*GP*TP*CP*T)-3'), ... Authors: Gaubitz, C, Liu, X, Pajak, J, Stone, N, Hayes, J, Demo, G, Kelch, B.A. Deposit date: 2022-01-13 Release date: 2022-02-16 Last modified: 2024-02-28 Method: ELECTRON MICROSCOPY (3.3 Å) Cite: Cryo-EM structures reveal high-resolution mechanism of a DNA polymerase sliding clamp loader. Elife, 11, 2022
7TKU	Structure of the yeast clamp loader (Replication Factor C RFC) bound to the open sliding clamp (Proliferating Cell Nuclear Antigen PCNA) Descriptor: ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, ... Authors: Gaubitz, C, Liu, X, Pajak, J, Stone, N, Hayes, J, Demo, G, Kelch, B.A. Deposit date: 2022-01-17 Release date: 2022-02-16 Last modified: 2024-02-21 Method: ELECTRON MICROSCOPY (4 Å) Cite: Cryo-EM structures reveal high-resolution mechanism of a DNA polymerase sliding clamp loader. Elife, 11, 2022
7THV	Structure of the yeast clamp loader (Replication Factor C RFC) bound to the sliding clamp (Proliferating Cell Nuclear Antigen PCNA) in an autoinhibited conformation Descriptor: ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, ... Authors: Gaubitz, C, Liu, X, Pajak, J, Stone, N, Hayes, J, Demo, G, Kelch, B.A. Deposit date: 2022-01-12 Release date: 2022-02-16 Last modified: 2024-02-28 Method: ELECTRON MICROSCOPY (4 Å) Cite: Cryo-EM structures reveal high-resolution mechanism of a DNA polymerase sliding clamp loader. Elife, 11, 2022
4OVF	E. coli sliding clamp in complex with (R)-6-chloro-2,3,4,9-tetrahydro-1H-carbazole-2-carboxylic acid Descriptor: (2R)-6-chloro-2,3,4,9-tetrahydro-1H-carbazole-2-carboxylic acid, CALCIUM ION, CHLORIDE ION, ... Authors: Yin, Z, Oakley, A.J. Deposit date: 2014-02-21 Release date: 2014-03-05 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (2.05 Å) Cite: Bacterial Sliding Clamp Inhibitors that Mimic the Sequential Binding Mechanism of Endogenous Linear Motifs. J.Med.Chem., 58, 2015
4PNW	E. coli sliding clamp in complex with (R)-6-bromo-9-(2-((S)-1-carboxy-2-phenylethylamino)-2-oxoethyl)-2,3,4,9-tetrahydro-1H-carbazole-2-carboxylic acid Descriptor: (2R)-6-bromo-9-(2-{[(1S)-1-carboxy-2-phenylethyl]amino}-2-oxoethyl)-2,3,4,9-tetrahydro-1H-carbazole-2-carboxylic acid, CALCIUM ION, CHLORIDE ION, ... Authors: Yin, Z, Oakley, A.J. Deposit date: 2014-02-21 Release date: 2014-03-05 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (2 Å) Cite: Bacterial Sliding Clamp Inhibitors that Mimic the Sequential Binding Mechanism of Endogenous Linear Motifs. J.Med.Chem., 58, 2015
4OVG	E. coli sliding clamp in complex with (R)-9-(2-amino-2-oxoethyl)-6-chloro-2,3,4,9-tetrahydro-1H-carbazole-2-carboxylic acid Descriptor: (2R)-9-(2-amino-2-oxoethyl)-6-chloro-2,3,4,9-tetrahydro-1H-carbazole-2-carboxylic acid, 1,2-ETHANEDIOL, CALCIUM ION, ... Authors: Yin, Z, Oakley, A.J. Deposit date: 2014-02-21 Release date: 2014-03-05 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Bacterial Sliding Clamp Inhibitors that Mimic the Sequential Binding Mechanism of Endogenous Linear Motifs. J.Med.Chem., 58, 2015
4PNV	E. coli sliding clamp apo-crystal in P21 space group with larger cell dimensions Descriptor: CALCIUM ION, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ... Authors: Yin, Z, Oakley, A.J. Deposit date: 2014-02-21 Release date: 2014-03-05 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (1.86 Å) Cite: Bacterial Sliding Clamp Inhibitors that Mimic the Sequential Binding Mechanism of Endogenous Linear Motifs. J.Med.Chem., 58, 2015
4PNU	E. coli sliding clamp in complex with (R)-6-bromo-9-(2-((R)-1-carboxy-2-phenylethylamino)-2-oxoethyl)-2,3,4,9-tetrahydro-1H-carbazole-2-carboxylic acid Descriptor: (2R)-6-bromo-9-(2-{[(1R)-1-carboxy-2-phenylethyl]amino}-2-oxoethyl)-2,3,4,9-tetrahydro-1H-carbazole-2-carboxylic acid, CALCIUM ION, CHLORIDE ION, ... Authors: Yin, Z, Oakley, A.J. Deposit date: 2014-02-21 Release date: 2014-03-05 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Bacterial Sliding Clamp Inhibitors that Mimic the Sequential Binding Mechanism of Endogenous Linear Motifs. J.Med.Chem., 58, 2015
4OVH	E. coli sliding clamp in complex with (R)-6-bromo-9-(2-(carboxymethylamino)-2-oxoethyl)-2,3,4,9-tetrahydro-1H-carbazole-2-carboxylic acid Descriptor: (2R)-6-bromo-9-{2-[(carboxymethyl)amino]-2-oxoethyl}-2,3,4,9-tetrahydro-1H-carbazole-2-carboxylic acid, CALCIUM ION, CHLORIDE ION, ... Authors: Yin, Z, Oakley, A.J. Deposit date: 2014-02-21 Release date: 2014-03-05 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (2.25 Å) Cite: Bacterial Sliding Clamp Inhibitors that Mimic the Sequential Binding Mechanism of Endogenous Linear Motifs. J.Med.Chem., 58, 2015
2POL	THREE-DIMENSIONAL STRUCTURE OF THE BETA SUBUNIT OF ESCHERICHIA COLI DNA POLYMERASE III HOLOENZYME: A SLIDING DNA CLAMP Descriptor: DNA POLYMERASE III (BETA SUBUNIT) Authors: Kong, X.-P, Kuriyan, J. Deposit date: 1992-11-13 Release date: 1994-01-31 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (2.5 Å) Cite: Three-dimensional structure of the beta subunit of E. coli DNA polymerase III holoenzyme: a sliding DNA clamp. Cell(Cambridge,Mass.), 69, 1992
6MAN	Crystal structure of a DnaN sliding clamp DNA polymerase III subunit beta from Rickettsia bellii RML369-C Descriptor: 1,2-ETHANEDIOL, Beta sliding clamp, THIOCYANATE ION Authors: Seattle Structural Genomics Center for Infectious Disease, Seattle Structural Genomics Center for Infectious Disease (SSGCID) Deposit date: 2018-08-28 Release date: 2018-09-05 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (2.35 Å) Cite: Crystal structure of a DnaN sliding clamp DNA polymerase III subunit beta from Rickettsia bellii RML369-C To Be Published
6DEG	Crystal structure of a DNA polymerase III subunit beta DnaN sliding clamp from Bartonella birtlesii LL-WM9 Descriptor: Beta sliding clamp Authors: Seattle Structural Genomics Center for Infectious Disease (SSGCID) Deposit date: 2018-05-11 Release date: 2018-05-30 Last modified: 2024-03-13 Method: X-RAY DIFFRACTION (2.45 Å) Cite: Crystal structure of a DNA polymerase III subunit beta DnaN sliding clamp from Bartonella birtlesii LL-WM9 To Be Published
6D47	Crystal structure of a DNA polymerase III subunit beta DnaN sliding clamp from Mycobacterium marinum Descriptor: Beta sliding clamp Authors: Seattle Structural Genomics Center for Infectious Disease (SSGCID) Deposit date: 2018-04-17 Release date: 2018-05-02 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (2.45 Å) Cite: Crystal structure of a DNA polymerase III subunit beta DnaN sliding clamp from Mycobacterium marinum To Be Published
3QG5	The Mre11:Rad50 complex forms an ATP dependent molecular clamp in DNA double-strand break repair Descriptor: GLYCEROL, Mre11, rad50 Authors: Lammens, K. Deposit date: 2011-01-24 Release date: 2011-04-20 Last modified: 2024-03-13 Method: X-RAY DIFFRACTION (3.4 Å) Cite: The Mre11:Rad50 Structure Shows an ATP-Dependent Molecular Clamp in DNA Double-Strand Break Repair. Cell(Cambridge,Mass.), 145, 2011

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