7TIB

Structure of the yeast clamp loader (Replication Factor C RFC) bound to the open sliding clamp (Proliferating Cell Nuclear Antigen PCNA) and primer-template DNA

Summary for 7TIB

Entry DOI	10.2210/pdb7tib/pdb
EMDB information	25616
Descriptor	Replication factor C subunit 1, MAGNESIUM ION, ADENOSINE-5'-DIPHOSPHATE, ... (11 entities in total)
Functional Keywords	sliding clamp, dna replication, aaa+, clamp loader, replication-dna complex, replication/dna
Biological source	Saccharomyces cerevisiae (baker's yeast) More
Total number of polymer chains	10
Total formula weight	355696.15
Authors	Gaubitz, C.,Liu, X.,Pajak, J.,Stone, N.,Hayes, J.,Demo, G.,Kelch, B.A. (deposition date: 2022-01-13, release date: 2022-02-16, Last modification date: 2024-02-28)
Primary citation	Gaubitz, C.,Liu, X.,Pajak, J.,Stone, N.P.,Hayes, J.A.,Demo, G.,Kelch PhD, B.A. Cryo-EM structures reveal high-resolution mechanism of a DNA polymerase sliding clamp loader. Elife, 11:-, 2022 Cited by PubMed: 35179493 DOI: 10.7554/eLife.74175 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3.4 Å)

Structure validation