PDB: 12203 resultsInfo pagesStatus searchChemie searchBIRD

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5MNJ	Structure of MDM2-MDMX-UbcH5B-ubiquitin complex Descriptor: E3 ubiquitin-protein ligase Mdm2, Polyubiquitin-B, Protein Mdm4, ... Authors: Klejnot, M, Huang, D.T. Deposit date: 2016-12-13 Release date: 2017-05-31 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (2.16 Å) Cite: Structural analysis of MDM2 RING separates degradation from regulation of p53 transcription activity. Nat. Struct. Mol. Biol., 24, 2017
7DG4	The co-crystal structure of DYRK2 with a small molecule inhibitor 6 Descriptor: 2,7-dimethoxy-9-(piperidin-4-ylmethylsulfanyl)acridine, Dual specificity tyrosine-phosphorylation-regulated kinase 2 Authors: Wei, T, Xiao, J. Deposit date: 2020-11-10 Release date: 2021-11-10 Last modified: 2024-10-09 Method: X-RAY DIFFRACTION (2.58 Å) Cite: Selective inhibition reveals the regulatory function of DYRK2 in protein synthesis and calcium entry. Elife, 11, 2022
7DH9	The co-crystal structure of DYRK2 with a small molecule inhibitor 7 Descriptor: Dual specificity tyrosine-phosphorylation-regulated kinase 2, [2,7-dimethoxy-9-(piperidin-4-ylmethylsulfanyl)acridin-4-yl]methanol Authors: Wei, T, Xiao, J. Deposit date: 2020-11-13 Release date: 2021-11-17 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (2.194 Å) Cite: Selective inhibition reveals the regulatory function of DYRK2 in protein synthesis and calcium entry. Elife, 11, 2022
7DHC	The co-crystal structure of DYRK2 with a small molecule inhibitor 10 Descriptor: 4-[bis(fluoranyl)methyl]-2,7-dimethoxy-9-(piperidin-4-ylmethylsulfanyl)acridine, Dual specificity tyrosine-phosphorylation-regulated kinase 2 Authors: Wei, T, Xiao, J. Deposit date: 2020-11-13 Release date: 2021-11-17 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (2.592 Å) Cite: Selective inhibition reveals the regulatory function of DYRK2 in protein synthesis and calcium entry. Elife, 11, 2022
7DHH	The co-crystal structure of DYRK2 with a small molecule inhibitor 19 Descriptor: Dual specificity tyrosine-phosphorylation-regulated kinase 2, [9-(azetidin-3-ylmethylsulfanyl)-2,7-dimethoxy-acridin-4-yl]methanol Authors: Wei, T, Xiao, J. Deposit date: 2020-11-14 Release date: 2021-11-17 Last modified: 2024-10-09 Method: X-RAY DIFFRACTION (2.486 Å) Cite: Selective inhibition reveals the regulatory function of DYRK2 in protein synthesis and calcium entry. Elife, 11, 2022
7DHO	The co-crystal structure of DYRK2 with a small molecule inhibitor 14 Descriptor: 2-methoxy-9-(piperidin-4-ylmethylsulfanyl)-7-propan-2-yloxy-acridine, Dual specificity tyrosine-phosphorylation-regulated kinase 2 Authors: Wei, T, Xiao, J. Deposit date: 2020-11-16 Release date: 2021-11-17 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (3.29 Å) Cite: Selective inhibition reveals the regulatory function of DYRK2 in protein synthesis and calcium entry. Elife, 11, 2022
7DHN	The co-crystal structure of DYRK2 with a small molecule inhibitor 20 Descriptor: 7-methoxy-2-methylsulfanyl-9-(piperidin-4-ylmethylsulfanyl)-[1,3]thiazolo[5,4-b]quinoline, Dual specificity tyrosine-phosphorylation-regulated kinase 2 Authors: Wei, T, Xiao, J. Deposit date: 2020-11-16 Release date: 2021-11-17 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (2.38 Å) Cite: Selective inhibition reveals the regulatory function of DYRK2 in protein synthesis and calcium entry. Elife, 11, 2022
7DHK	The co-crystal structure of DYRK2 with a small molecule inhibitor 13 Descriptor: 2-methoxy-7-phenylmethoxy-9-(piperidin-4-ylmethylsulfanyl)acridine, Dual specificity tyrosine-phosphorylation-regulated kinase 2 Authors: Wei, T, Xiao, J. Deposit date: 2020-11-16 Release date: 2021-11-17 Last modified: 2024-10-09 Method: X-RAY DIFFRACTION (2.341 Å) Cite: Selective inhibition reveals the regulatory function of DYRK2 in protein synthesis and calcium entry. Elife, 11, 2022
7DHV	The co-crystal structure of DYRK2 with a small molecule inhibitor 8 Descriptor: 2,7-dimethoxy-9-(piperidin-4-ylmethylsulfanyl)acridine-4-carboxylic acid, Dual specificity tyrosine-phosphorylation-regulated kinase 2 Authors: Wei, T, Xiao, J. Deposit date: 2020-11-17 Release date: 2021-11-17 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (2.679 Å) Cite: Selective inhibition reveals the regulatory function of DYRK2 in protein synthesis and calcium entry. Elife, 11, 2022
7DJO	The co-crystal structure of DYRK2 with a small molecule inhibitor 17 Descriptor: Dual specificity tyrosine-phosphorylation-regulated kinase 2, [2,7-dimethoxy-9-[[(3S)-pyrrolidin-3-yl]methylsulfanyl]acridin-4-yl]methanol Authors: Wei, T, Xiao, J. Deposit date: 2020-11-20 Release date: 2021-11-24 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (2.499 Å) Cite: Selective inhibition reveals the regulatory function of DYRK2 in protein synthesis and calcium entry. Elife, 11, 2022
7DL6	The co-crystal structure of DYRK2 with a small molecule inhibitor 18 Descriptor: Dual specificity tyrosine-phosphorylation-regulated kinase 2, [2,7-dimethoxy-9-[[(3R)-pyrrolidin-3-yl]methylsulfanyl]acridin-4-yl]methanol Authors: Wei, T, Xiao, J. Deposit date: 2020-11-26 Release date: 2021-12-01 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (2.648 Å) Cite: Selective inhibition reveals the regulatory function of DYRK2 in protein synthesis and calcium entry. Elife, 11, 2022
3DQ7	Structure of the Yellow Fluorescent Protein Citrine Frozen at 1920 Atmospheres Number 1: Structure 17 in a Series of 26 High Pressure Structures Descriptor: Green fluorescent protein Authors: Barstow, B, Kim, C.U. Deposit date: 2008-07-09 Release date: 2008-09-23 Last modified: 2023-11-15 Method: X-RAY DIFFRACTION (1.23 Å) Cite: Alteration of citrine structure by hydrostatic pressure explains the accompanying spectral shift. Proc.Natl.Acad.Sci.Usa, 105, 2008
3DQK	Structure of the Yellow Fluorescent Protein Citrine Frozen at 1000 Atmospheres Number 2: Structure 6 in a Series of 26 High Pressure Structures Descriptor: Green fluorescent protein Authors: Barstow, B, Kim, C.U. Deposit date: 2008-07-09 Release date: 2008-09-23 Last modified: 2023-11-15 Method: X-RAY DIFFRACTION (1.4 Å) Cite: Alteration of citrine structure by hydrostatic pressure explains the accompanying spectral shift. Proc.Natl.Acad.Sci.Usa, 105, 2008
3DPZ	Structure of the Yellow Fluorescent Protein Citrine Frozen at 4000 Atmospheres Number 3: Structure 25 in a Series of 26 High Pressure Structures Descriptor: Green fluorescent protein Authors: Barstow, B, Kim, C.U. Deposit date: 2008-07-09 Release date: 2008-09-23 Last modified: 2023-11-15 Method: X-RAY DIFFRACTION (1.7 Å) Cite: Alteration of citrine structure by hydrostatic pressure explains the accompanying spectral shift. Proc.Natl.Acad.Sci.Usa, 105, 2008
3DQ8	Structure of the Yellow Fluorescent Protein Citrine Frozen at 1500 Atmospheres Number 2: Structure 16 in a Series of 26 High Pressure Structures Descriptor: Green fluorescent protein Authors: Barstow, B, Kim, C.U. Deposit date: 2008-07-09 Release date: 2008-09-23 Last modified: 2023-11-15 Method: X-RAY DIFFRACTION (1.51 Å) Cite: Alteration of citrine structure by hydrostatic pressure explains the accompanying spectral shift. Proc.Natl.Acad.Sci.Usa, 105, 2008
3DPW	Structure of the Yellow Fluorescent Protein Citrine Frozen at 1 Atmosphere Number 1: Structure 1 in a Series of 26 High Pressure Structures Descriptor: Green fluorescent protein Authors: Barstow, B, Kim, C.U. Deposit date: 2008-07-09 Release date: 2008-09-23 Last modified: 2023-11-15 Method: X-RAY DIFFRACTION (1.59 Å) Cite: Alteration of citrine structure by hydrostatic pressure explains the accompanying spectral shift. Proc.Natl.Acad.Sci.Usa, 105, 2008
3DQ4	Structure of the Yellow Fluorescent Protein Citrine Frozen at 2000 Atmospheres Number 2: Structure 20 in a Series of 26 High Pressure Structures Descriptor: Green fluorescent protein Authors: Barstow, B, Kim, C.U. Deposit date: 2008-07-09 Release date: 2008-09-23 Last modified: 2023-11-15 Method: X-RAY DIFFRACTION (1.47 Å) Cite: Alteration of citrine structure by hydrostatic pressure explains the accompanying spectral shift. Proc.Natl.Acad.Sci.Usa, 105, 2008
4TZP	As Grown, Untreated Co-crystals of the Ternary Complex Containing a T-box Stem I RNA, its cognate tRNAGly, and B. subtilis YbxF protein Descriptor: Ribosome-associated protein L7Ae-like, engineered tRNA, glyQ T-box Stem I Authors: Zhang, J, Ferre-D'Amare, A.R. Deposit date: 2014-07-10 Release date: 2014-09-10 Last modified: 2023-11-15 Method: X-RAY DIFFRACTION (8.503 Å) Cite: Dramatic Improvement of Crystals of Large RNAs by Cation Replacement and Dehydration. Structure, 22, 2014
7RYF	A. baumannii Ribosome-TP-6076 complex: P-site tRNA 70S Descriptor: (4S,4aS,5aR,12aS)-4-(diethylamino)-3,10,12,12a-tetrahydroxy-1,11-dioxo-8-[(2S)-pyrrolidin-2-yl]-7-(trifluoromethyl)-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide, 16S Ribosomal RNA, 23S ribosomal RNA, ... Authors: Morgan, C.E, Yu, E.W. Deposit date: 2021-08-25 Release date: 2022-02-02 Last modified: 2024-06-05 Method: ELECTRON MICROSCOPY (2.65 Å) Cite: An Analysis of the Novel Fluorocycline TP-6076 Bound to Both the Ribosome and Multidrug Efflux Pump AdeJ from Acinetobacter baumannii. Mbio, 13, 2022
7RYG	A. baumannii Ribosome-TP-6076 complex: E-site tRNA 70S Descriptor: (4S,4aS,5aR,12aS)-4-(diethylamino)-3,10,12,12a-tetrahydroxy-1,11-dioxo-8-[(2S)-pyrrolidin-2-yl]-7-(trifluoromethyl)-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide, 16S Ribosomal RNA, 23S ribosomal RNA, ... Authors: Morgan, C.E, Yu, E.W. Deposit date: 2021-08-25 Release date: 2022-02-02 Last modified: 2024-06-05 Method: ELECTRON MICROSCOPY (2.38 Å) Cite: An Analysis of the Novel Fluorocycline TP-6076 Bound to Both the Ribosome and Multidrug Efflux Pump AdeJ from Acinetobacter baumannii. Mbio, 13, 2022
7RYH	A. baumannii Ribosome-TP-6076 complex: Empty 70S Descriptor: (4S,4aS,5aR,12aS)-4-(diethylamino)-3,10,12,12a-tetrahydroxy-1,11-dioxo-8-[(2S)-pyrrolidin-2-yl]-7-(trifluoromethyl)-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide, 16S Ribosomal RNA, 23S ribosomal RNA, ... Authors: Morgan, C.E, Yu, E.W. Deposit date: 2021-08-25 Release date: 2022-02-02 Last modified: 2024-06-05 Method: ELECTRON MICROSCOPY (2.43 Å) Cite: An Analysis of the Novel Fluorocycline TP-6076 Bound to Both the Ribosome and Multidrug Efflux Pump AdeJ from Acinetobacter baumannii. Mbio, 13, 2022
3DQ1	Structure of the Yellow Fluorescent Protein Citrine Frozen at 4000 Atmospheres Number 2: Structure 24 in a Series of 26 High Pressure Structures Descriptor: Green fluorescent protein Authors: Barstow, B, Kim, C.U. Deposit date: 2008-07-09 Release date: 2008-09-23 Last modified: 2023-11-15 Method: X-RAY DIFFRACTION (1.7 Å) Cite: Alteration of citrine structure by hydrostatic pressure explains the accompanying spectral shift. Proc.Natl.Acad.Sci.Usa, 105, 2008
3DQA	Structure of the Yellow Fluorescent Protein Citrine Frozen at 1250 Atmospheres Number 4: Structure 14 in a Series of 26 High Pressure Structures Descriptor: Green fluorescent protein Authors: Barstow, B, Kim, C.U. Deposit date: 2008-07-09 Release date: 2008-09-23 Last modified: 2023-11-15 Method: X-RAY DIFFRACTION (1.44 Å) Cite: Alteration of citrine structure by hydrostatic pressure explains the accompanying spectral shift. Proc.Natl.Acad.Sci.Usa, 105, 2008
3DQ2	Structure of the Yellow Fluorescent Protein Citrine Frozen at 4000 Atmospheres Number 1: Structure 23 in a Series of 26 High Pressure Structures Descriptor: Green fluorescent protein Authors: Barstow, B, Kim, C.U. Deposit date: 2008-07-09 Release date: 2008-09-23 Last modified: 2023-11-15 Method: X-RAY DIFFRACTION (1.6 Å) Cite: Alteration of citrine structure by hydrostatic pressure explains the accompanying spectral shift. Proc.Natl.Acad.Sci.Usa, 105, 2008
3DQC	Structure of the Yellow Fluorescent Protein Citrine Frozen at 1250 Atmospheres Number 3: Structure 13 in a Series of 26 High Pressure Structures Descriptor: Green fluorescent protein Authors: Barstow, B, Kim, C.U. Deposit date: 2008-07-09 Release date: 2008-09-23 Last modified: 2023-11-15 Method: X-RAY DIFFRACTION (1.49 Å) Cite: Alteration of citrine structure by hydrostatic pressure explains the accompanying spectral shift. Proc.Natl.Acad.Sci.Usa, 105, 2008

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