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7UBA
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BU of 7uba by Molmil
Structure of fungal Hop1 CBR domain
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, HORMA domain-containing protein, PENTAETHYLENE GLYCOL, ...
Authors:Ur, S.N, Corbett, K.D.
Deposit date:2022-03-14
Release date:2023-03-29
Last modified:2024-04-10
Method:X-RAY DIFFRACTION (1.599 Å)
Cite:Chromatin binding by HORMAD proteins regulates meiotic recombination initiation.
Embo J., 43, 2024
6CSF
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BU of 6csf by Molmil
Crystal structure of sodium/alanine symporter AgcS with D-alanine bound
Descriptor: D-ALANINE, Monoclonal antibody FAB heavy chain, Monoclonal antibody FAB light chain, ...
Authors:Ma, J, Reyes, F.E, Gonen, T.
Deposit date:2018-03-20
Release date:2019-01-30
Last modified:2019-02-20
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Structural basis for substrate binding and specificity of a sodium-alanine symporter AgcS.
Proc. Natl. Acad. Sci. U.S.A., 116, 2019
8E2L
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BU of 8e2l by Molmil
Structure of Lates calcarifer Twinkle helicase with ATP and DNA
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, DNA (5'-D(P*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*T)-3'), MAGNESIUM ION, ...
Authors:Gao, Y, Li, Z.
Deposit date:2022-08-15
Release date:2022-11-02
Last modified:2024-06-12
Method:ELECTRON MICROSCOPY (3.51 Å)
Cite:Structural and dynamic basis of DNA capture and translocation by mitochondrial Twinkle helicase.
Nucleic Acids Res., 50, 2022
6ON0
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BU of 6on0 by Molmil
STRUCTURE OF N15 CRO COMPLEXED WITH CONSENSUS OPERATOR DNA
Descriptor: DNA (5'-D(*TP*TP*TP*AP*TP*AP*GP*CP*TP*AP*GP*CP*TP*AP*TP*AP*A)-3'), Gp39
Authors:Hall, B.M, Roberts, S.A, Cordes, M.H.J.
Deposit date:2019-04-19
Release date:2019-05-15
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Extreme divergence between one-to-one orthologs: the structure of N15 Cro bound to operator DNA and its relationship to the lambda Cro complex.
Nucleic Acids Res., 47, 2019
4YZY
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BU of 4yzy by Molmil
Crystal structures reveal transient PERK luminal domain tetramerization in ER stress signaling
Descriptor: Eukaryotic translation initiation factor 2-alpha kinase 3
Authors:Carrara, M, Prischi, F, Ali, M.M.U.
Deposit date:2015-03-25
Release date:2015-05-13
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Crystal structures reveal transient PERK luminal domain tetramerization in endoplasmic reticulum stress signaling.
Embo J., 34, 2015
1YQZ
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BU of 1yqz by Molmil
Structure of Coenzyme A-Disulfide Reductase from Staphylococcus aureus refined at 1.54 Angstrom resolution
Descriptor: CHLORIDE ION, COENZYME A, FLAVIN-ADENINE DINUCLEOTIDE, ...
Authors:Mallett, T.C, Wallen, J.R, Sakai, H, Luba, J, Parsonage, D, Karplus, P.A, Tsukihara, T, Claiborne, A.
Deposit date:2005-02-02
Release date:2006-05-09
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.54 Å)
Cite:Structure of coenzyme A-disulfide reductase from Staphylococcus aureus at 1.54 A resolution.
Biochemistry, 45, 2006
1KYT
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BU of 1kyt by Molmil
Crystal Structure of Thermoplasma acidophilum 0175 (APC014)
Descriptor: CALCIUM ION, hypothetical protein TA0175
Authors:Kim, Y, Joachimiak, A, Edwards, A, Xu, X, Pennycooke, M, Gu, J, Cheung, F, Christendat, D, Midwest Center for Structural Genomics (MCSG)
Deposit date:2002-02-05
Release date:2003-01-21
Last modified:2021-10-27
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Crystal Structure of Thermoplasma acidophilum 0175 (APC014)
To be published
6OS4
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BU of 6os4 by Molmil
Calmodulin in complex with farnesyl cysteine methyl ester
Descriptor: CALCIUM ION, Calmodulin-1, s-farnesyl-l-cysteine methyl ester
Authors:Grant, B.M.M, Enomoto, M, Lee, K.Y, Back, S.I, Gebregiworgis, T, Ishiyama, N, Ikura, M, Marshall, C.
Deposit date:2019-05-01
Release date:2020-04-08
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Calmodulin disrupts plasma membrane localization of farnesylated KRAS4b by sequestering its lipid moiety.
Sci.Signal., 13, 2020
1L3N
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BU of 1l3n by Molmil
The Solution Structure of Reduced Dimeric Copper Zinc SOD: the Structural Effects of Dimerization
Descriptor: COPPER (I) ION, ZINC ION, superoxide dismutase [Cu-Zn]
Authors:Banci, L, Bertini, I, Cramaro, F, Del Conte, R, Viezzoli, M.S.
Deposit date:2002-02-28
Release date:2002-05-08
Last modified:2021-10-27
Method:SOLUTION NMR
Cite:The solution structure of reduced dimeric copper zinc superoxide dismutase. The structural effects of dimerization
Eur.J.Biochem., 269, 2002
1L1N
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BU of 1l1n by Molmil
POLIOVIRUS 3C PROTEINASE
Descriptor: Genome polyprotein: Picornain 3C
Authors:Mosimann, S.C, Chernaia, M.M, Sia, S, Plotch, S, James, M.N.G.
Deposit date:2002-02-19
Release date:2002-04-10
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Refined X-ray crystallographic structure of the poliovirus 3C gene product.
J.Mol.Biol., 273, 1997
6BUT
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BU of 6but by Molmil
Solution structure of full-length apo mammalian calmodulin bound to the IQ motif of the human voltage-gated sodium channel NaV1.2
Descriptor: Calmodulin-1, Sodium channel protein type 2 subunit alpha
Authors:Mahling, R, Kilpatrick, A.M, Shea, M.A.
Deposit date:2017-12-11
Release date:2019-06-19
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:Na V 1.2 EFL domain allosterically enhances Ca 2+ binding to sites I and II of WT and pathogenic calmodulin mutants bound to the channel CTD.
Structure, 2021
8E18
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BU of 8e18 by Molmil
Crystal structure of apo TnmK1
Descriptor: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Secreted hydrolase
Authors:Liu, Y.-C, Gui, C, Shen, B.
Deposit date:2022-08-10
Release date:2022-11-09
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.14 Å)
Cite:Intramolecular C-C Bond Formation Links Anthraquinone and Enediyne Scaffolds in Tiancimycin Biosynthesis.
J.Am.Chem.Soc., 144, 2022
6OF4
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BU of 6of4 by Molmil
Precursor ribosomal RNA processing complex, apo-state.
Descriptor: CLP1_P domain-containing protein, Ribonuclease
Authors:Pillon, M.C, Hsu, A.L, Krahn, J.M, Williams, J.G, Goslen, K.H, Sobhany, M, Borgnia, M.J, Stanley, R.E.
Deposit date:2019-03-28
Release date:2019-09-11
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Cryo-EM reveals active site coordination within a multienzyme pre-rRNA processing complex.
Nat.Struct.Mol.Biol., 26, 2019
1KAW
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BU of 1kaw by Molmil
STRUCTURE OF SINGLE STRANDED DNA BINDING PROTEIN (SSB)
Descriptor: SINGLE-STRANDED DNA BINDING PROTEIN
Authors:Raghunathan, S, Waksman, G.
Deposit date:1996-12-06
Release date:1997-12-31
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Crystal structure of the homo-tetrameric DNA binding domain of Escherichia coli single-stranded DNA-binding protein determined by multiwavelength x-ray diffraction on the selenomethionyl protein at 2.9-A resolution.
Proc.Natl.Acad.Sci.USA, 94, 1997
8E19
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BU of 8e19 by Molmil
Crystal structure of TnmK1 complexed with TNM H
Descriptor: (1R,8S,13S)-8-[(4-hydroxy-9,10-dioxo-9,10-dihydroanthracen-1-yl)amino]-12-methoxy-10-methylbicyclo[7.3.1]trideca-9,11-diene-2,6-diyne-13-carbaldehyde, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, SUCCINIC ACID, ...
Authors:Liu, Y.-C, Gui, C, Shen, B.
Deposit date:2022-08-10
Release date:2022-11-09
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.03 Å)
Cite:Intramolecular C-C Bond Formation Links Anthraquinone and Enediyne Scaffolds in Tiancimycin Biosynthesis.
J.Am.Chem.Soc., 144, 2022
1YUK
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BU of 1yuk by Molmil
The crystal structure of the PSI/Hybrid domain/ I-EGF1 segment from the human integrin beta2 at 1.8 resolution
Descriptor: 2-acetamido-2-deoxy-alpha-D-glucopyranose, Integrin beta-2 A chain, Integrin beta-2 B chain
Authors:Shi, M, Sundramurthy, K, Liu, B, Tan, S.M, Law, S.K, Lescar, J.
Deposit date:2005-02-14
Release date:2005-07-19
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:The Crystal Structure of the Plexin-Semaphorin-Integrin Domain/Hybrid Domain/I-EGF1 Segment from the Human Integrin {beta}2 Subunit at 1.8-A Resolution
J.Biol.Chem., 280, 2005
8FZY
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BU of 8fzy by Molmil
Bacteroides spp. Ntox15 domain type VI secretion system effector Tde1
Descriptor: 1,2-ETHANEDIOL, Ntox15 domain-containing protein, SULFATE ION
Authors:Bosch, D.E, Mougous, J.D.
Deposit date:2023-01-30
Release date:2023-07-05
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structural disruption of Ntox15 nuclease effector domains by immunity proteins protects against type VI secretion system intoxication in Bacteroidales.
Mbio, 14, 2023
1O6X
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BU of 1o6x by Molmil
NMR solution structure of the activation domain of human procarboxypeptidase A2
Descriptor: PROCARBOXYPEPTIDASE A2
Authors:Jimenez, M.A, Villegas, V, Santoro, J, Serrano, L, Vendrell, J, Aviles, F.X, Rico, M.
Deposit date:2002-10-17
Release date:2003-01-30
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:NMR Solution Structure of the Activation Domain of Human Procarboxypeptidase A2
Protein Sci., 12, 2003
6BHO
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BU of 6bho by Molmil
Green Light-Absorbing State of NpR6012g4, a Red/Green Cyanobacteriochrome
Descriptor: Methyl-accepting chemotaxis sensory transducer with phytochrome sensor, PHYCOCYANOBILIN
Authors:Lim, S, Yu, Q, Rockwell, N.C, Martin, S.S, Lagarias, J.C, Ames, J.B.
Deposit date:2017-10-31
Release date:2018-04-18
Last modified:2019-12-04
Method:SOLUTION NMR
Cite:Correlating structural and photochemical heterogeneity in cyanobacteriochrome NpR6012g4.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
1ZGU
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BU of 1zgu by Molmil
Solution structure of the human Mms2-Ubiquitin complex
Descriptor: Ubiquitin, Ubiquitin-conjugating enzyme E2 variant 2
Authors:Lewis, M.J, Saltibus, L.F, Hau, D.D, Xiao, W, Spyracopoulos, L.
Deposit date:2005-04-22
Release date:2006-04-04
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Structural Basis for Non-Covalent Interaction Between Ubiquitin and the Ubiquitin Conjugating Enzyme Variant Human MMS2.
J.Biomol.Nmr, 34, 2006
1L9W
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BU of 1l9w by Molmil
CRYSTAL STRUCTURE OF 3-DEHYDROQUINASE FROM SALMONELLA TYPHI COMPLEXED WITH REACTION PRODUCT
Descriptor: 3-AMINO-4,5-DIHYDROXY-CYCLOHEX-1-ENECARBOXYLATE, 3-dehydroquinate dehydratase aroD
Authors:Lee, W.H, Perles, L.A, Nagem, R.A.P, Shrive, A.K, Hawkins, A, Sawyer, L, Polikarpov, I.
Deposit date:2002-03-26
Release date:2003-03-26
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Comparison of different crystal forms of 3-dehydroquinase from Salmonella typhi and its implication for the enzyme activity.
Acta Crystallogr.,Sect.D, 58, 2002
5YXW
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BU of 5yxw by Molmil
Crystal structure of the prefusion form of measles virus fusion protein
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, glycoprotein F1,measles virus fusion protein, ...
Authors:Hashiguchi, T, Fukuda, Y, Matsuoka, R, Kuroda, D, Kubota, M, Shirogane, Y, Watanabe, S, Tsumoto, K, Kohda, D, Plemper, R.K, Yanagi, Y.
Deposit date:2017-12-07
Release date:2018-02-21
Last modified:2022-03-23
Method:X-RAY DIFFRACTION (2.776 Å)
Cite:Structures of the prefusion form of measles virus fusion protein in complex with inhibitors.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
8E90
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BU of 8e90 by Molmil
Inhibition of Human Menin by SNDX-5613
Descriptor: 1,2-ETHANEDIOL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 2-({4-[7-({(1r,4r)-4-[(ethanesulfonyl)amino]cyclohexyl}methyl)-2,7-diazaspiro[3.5]nonan-2-yl]pyrimidin-5-yl}oxy)-N-ethyl-5-fluoro-N-(propan-2-yl)benzamide, ...
Authors:McKeever, B.M, KULKARNI, S, McGeehan, G.M.
Deposit date:2022-08-26
Release date:2022-12-14
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:MEN1 mutations mediate clinical resistance to menin inhibition.
Nature, 615, 2023
8GPB
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BU of 8gpb by Molmil
STRUCTURAL MECHANISM FOR GLYCOGEN PHOSPHORYLASE CONTROL BY PHOSPHORYLATION AND AMP
Descriptor: ADENOSINE MONOPHOSPHATE, GLYCOGEN PHOSPHORYLASE B, PYRIDOXAL-5'-PHOSPHATE
Authors:Barford, D, Hu, S.-H, Johnson, L.N.
Deposit date:1990-11-13
Release date:1992-10-15
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural mechanism for glycogen phosphorylase control by phosphorylation and AMP.
J.Mol.Biol., 218, 1991
1O70
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BU of 1o70 by Molmil
Novel Fold Revealed by the Structure of a FAS1 Domain Pair from the Insect Cell Adhesion Molecule Fasciclin I
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, FASCICLIN I, SULFATE ION
Authors:Clout, N.J, Tisi, D, Hohenester, E.
Deposit date:2002-10-23
Release date:2003-02-13
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Novel Fold Revealed by the Structure of a Fas1 Domain Pair from the Insect Cell Adhesion Molecule Fasciclin I
Structure, 11, 2003

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