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7OBG
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BU of 7obg by Molmil
Crystal structure of 14-3-3 sigma in complex with NPM1 phosphopeptide
Descriptor: 14-3-3 protein sigma, CHLORIDE ION, MAGNESIUM ION, ...
Authors:Centorrino, F, Andlovic, B, Ottmann, C.
Deposit date:2021-04-22
Release date:2022-05-04
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:IFN alpha primes cancer cells for Fusicoccin-induced cell death via 14-3-3 PPI stabilization.
Cell Chem Biol, 2023
7OBS
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BU of 7obs by Molmil
Crystal structure of 14-3-3 sigma in complex with RIPK2 phosphopeptide
Descriptor: 14-3-3 protein sigma, CALCIUM ION, MAGNESIUM ION, ...
Authors:Centorrino, F, Andlovic, B, Ottmann, C.
Deposit date:2021-04-23
Release date:2022-05-04
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:IFN alpha primes cancer cells for Fusicoccin-induced cell death via 14-3-3 PPI stabilization.
Cell Chem Biol, 2023
4V10
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BU of 4v10 by Molmil
Skelemin Association with alpha2b,beta3 Integrin: A Structural Model
Descriptor: MYOMESIN-1
Authors:Gorbatyuk, V, Deshmukh, L, Nguyen, K, Vinogradova, O.
Deposit date:2014-09-19
Release date:2014-10-08
Last modified:2024-06-19
Method:SOLUTION NMR
Cite:Skelemin Association with Alphaiibbeta3 Integrin: A Structural Model.
Biochemistry, 53, 2014
6ZD8
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BU of 6zd8 by Molmil
Crystal structure of YTHDC1 T379V mutant
Descriptor: SULFATE ION, YTHDC1
Authors:Bedi, R.K, Li, Y, Caflisch, A.
Deposit date:2020-06-14
Release date:2021-01-13
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Atomistic and Thermodynamic Analysis of N6-Methyladenosine (m 6 A) Recognition by the Reader Domain of YTHDC1.
J Chem Theory Comput, 17, 2021
4UZZ
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BU of 4uzz by Molmil
Crystal structure of the TtIFT52-46 complex
Descriptor: INTRAFLAGELLAR TRANSPORT COMPLEX B PROTEIN 46 CARBOXY-TERMINAL PROTEIN, INTRAFLAGELLAR TRANSPORTER-LIKE PROTEIN
Authors:Braeuer, P, Taschner, M, Lorentzen, E.
Deposit date:2014-09-09
Release date:2014-11-05
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.318 Å)
Cite:Crystal Structures of Ift70/52 and Ift52/46 Provide Insight Into Intraflagellar Transport B Core Complex Assembly.
J.Cell Biol., 207, 2014
4WJ5
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BU of 4wj5 by Molmil
Structure of HLA-A2 in complex with an altered peptide ligands based on Mart-1 variant epitope
Descriptor: Beta-2-microglobulin, GLYCEROL, HLA class I histocompatibility antigen, ...
Authors:Celie, P.H.N, Rodenko, B, Ovaa, H.
Deposit date:2014-09-29
Release date:2014-10-29
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Altered Peptide Ligands Revisited: Vaccine Design through Chemically Modified HLA-A2-Restricted T Cell Epitopes.
J Immunol., 193, 2014
4WGF
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BU of 4wgf by Molmil
YcaC from Pseudomonas aeruginosa with hexane-2,5-diol and covalent acrylamide
Descriptor: (2R,5R)-hexane-2,5-diol, CHLORIDE ION, PROPIONAMIDE, ...
Authors:Groftehauge, M.K, Truan, D, Vasil, A, Denny, P.W, Vasil, M.L, Pohl, E.
Deposit date:2014-09-18
Release date:2015-07-29
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.34020686 Å)
Cite:Crystal Structure of a Hidden Protein, YcaC, a Putative Cysteine Hydrolase from Pseudomonas aeruginosa, with and without an Acrylamide Adduct.
Int J Mol Sci, 16, 2015
4WW5
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BU of 4ww5 by Molmil
Crystal structure of binary complex Bud32-Cgi121 in complex with AMPP
Descriptor: ACETATE ION, EKC/KEOPS complex subunit BUD32, EKC/KEOPS complex subunit CGI121, ...
Authors:Zhang, W.
Deposit date:2014-11-10
Release date:2015-03-18
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (1.997 Å)
Cite:Crystal structures of the Gon7/Pcc1 and Bud32/Cgi121 complexes provide a model for the complete yeast KEOPS complex.
Nucleic Acids Res., 43, 2015
4WW9
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BU of 4ww9 by Molmil
Crystal structure of binary complex Bud32-Cgi121 in complex with ADP
Descriptor: ACETATE ION, ADENOSINE-5'-DIPHOSPHATE, EKC/KEOPS complex subunit BUD32, ...
Authors:Zhang, W, Van Tilbeurgh, H.
Deposit date:2014-11-10
Release date:2015-03-18
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (1.951 Å)
Cite:Crystal structures of the Gon7/Pcc1 and Bud32/Cgi121 complexes provide a model for the complete yeast KEOPS complex.
Nucleic Acids Res., 43, 2015
4X6E
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BU of 4x6e by Molmil
CD1a binary complex with lysophosphatidylcholine
Descriptor: (4R,7R,18Z)-4,7-dihydroxy-N,N,N-trimethyl-10-oxo-3,5,9-trioxa-4-phosphaheptacos-18-en-1-aminium 4-oxide, Beta-2-microglobulin, D-MALATE, ...
Authors:Birkinshaw, R.W, Rossjohn, J.
Deposit date:2014-12-08
Release date:2015-01-28
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:alpha beta T cell antigen receptor recognition of CD1a presenting self lipid ligands.
Nat.Immunol., 16, 2015
4WV6
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BU of 4wv6 by Molmil
Heterodimer of Importin alpha 1 with nuclear localization signal of TAF8
Descriptor: 1,2-ETHANEDIOL, Importin subunit alpha-1, Transcription initiation factor TFIID subunit 8
Authors:Trowitzsch, S.
Deposit date:2014-11-04
Release date:2015-01-28
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Cytoplasmic TAF2-TAF8-TAF10 complex provides evidence for nuclear holo-TFIID assembly from preformed submodules.
Nat Commun, 6, 2015
4WH0
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BU of 4wh0 by Molmil
YcaC from Pseudomonas aeruginosa with S-mercaptocysteine active site cysteine
Descriptor: CHLORIDE ION, Putative hydrolase
Authors:Groftehauge, M.K, Truan, D, Vasil, A, Denny, P.W, Vasil, M.L, Pohl, E.
Deposit date:2014-09-19
Release date:2015-07-29
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.563 Å)
Cite:Crystal Structure of a Hidden Protein, YcaC, a Putative Cysteine Hydrolase from Pseudomonas aeruginosa, with and without an Acrylamide Adduct.
Int J Mol Sci, 16, 2015
4X6F
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BU of 4x6f by Molmil
CD1a binary complex with sphingomyelin
Descriptor: (4S,7S,23Z)-4-hydroxy-7-[(1S,2Z)-1-hydroxyhexadec-2-en-1-yl]-N,N,N-trimethyl-9-oxo-3,5-dioxa-8-aza-4-phosphadotriacont- 23-en-1-aminium 4-oxide, Beta-2-microglobulin, T-cell surface glycoprotein CD1a
Authors:Birkinshaw, R.W, Rossjohn, J.
Deposit date:2014-12-08
Release date:2015-02-04
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.91 Å)
Cite:alpha beta T cell antigen receptor recognition of CD1a presenting self lipid ligands.
Nat.Immunol., 16, 2015
1RW5
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BU of 1rw5 by Molmil
Solution structure of human prolactin
Descriptor: Prolactin
Authors:Teilum, K, Hoch, J, Martial, J.A, Kragelund, B.B.
Deposit date:2003-12-16
Release date:2005-02-22
Last modified:2022-03-02
Method:SOLUTION NMR
Cite:Solution structure of human prolactin
J.Mol.Biol., 351, 2005
4X6C
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BU of 4x6c by Molmil
CD1a ternary complex with lysophosphatidylcholine and BK6 TCR
Descriptor: (4R,7R,18Z)-4,7-dihydroxy-N,N,N-trimethyl-10-oxo-3,5,9-trioxa-4-phosphaheptacos-18-en-1-aminium 4-oxide, 2-acetamido-2-deoxy-beta-D-glucopyranose, Beta-2-microglobulin, ...
Authors:Birkinshaw, R.W, Rossjohn, J.
Deposit date:2014-12-08
Release date:2015-01-28
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:alpha beta T cell antigen receptor recognition of CD1a presenting self lipid ligands.
Nat.Immunol., 16, 2015
4WMH
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BU of 4wmh by Molmil
Structure of heme oxygenase-2 containing residues 1-288 lacking the membrane spanning region
Descriptor: CHLORIDE ION, Heme oxygenase 2
Authors:Bianchetti, C.M, Li, Y, Ragsdale, S.W, Phillips Jr, G.N, Center for Eukaryotic Structural Genomics (CESG)
Deposit date:2014-10-09
Release date:2014-11-05
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structure of heme oxygenase-2 containing residues 1-288 lacking the membrane spanning region
To Be Published
3HW2
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BU of 3hw2 by Molmil
Crystal structure of the SifA-SKIP(PH) complex
Descriptor: Pleckstrin homology domain-containing family M member 2, Protein sifA
Authors:Diacovich, L, Dumont, A, Lafitte, D, Soprano, E, Guilhon, A.-A, Bignon, C, Gorvel, J.-P, Bourne, Y, Meresse, S.
Deposit date:2009-06-17
Release date:2009-11-03
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Interaction between the SifA virulence factor and its host target skip is essential for salmonella pathogenesis
J.Biol.Chem., 284, 2009
5D22
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BU of 5d22 by Molmil
Structure of ovine granulocyte-macrophage colony-stimulating factor
Descriptor: 1,2-ETHANEDIOL, ACETATE ION, Granulocyte-macrophage colony-stimulating factor
Authors:Felix, J, Savvides, S.N.
Deposit date:2015-08-05
Release date:2016-11-16
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.994 Å)
Cite:Structural basis of GM-CSF and IL-2 sequestration by the viral decoy receptor GIF.
Nat Commun, 7, 2016
1CMK
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BU of 1cmk by Molmil
CRYSTAL STRUCTURES OF THE MYRISTYLATED CATALYTIC SUBUNIT OF CAMP-DEPENDENT PROTEIN KINASE REVEAL OPEN AND CLOSED CONFORMATIONS
Descriptor: IODIDE ION, MYRISTIC ACID, cAMP-DEPENDENT PROTEIN KINASE CATALYTIC SUBUNIT, ...
Authors:Zheng, J, Knighton, D.R, Xuong, N.-H, Taylor, S.S, Sowadski, J.M, Ten Eyck, L.F.
Deposit date:1993-11-18
Release date:1994-05-31
Last modified:2024-06-05
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Crystal structures of the myristylated catalytic subunit of cAMP-dependent protein kinase reveal open and closed conformations.
Protein Sci., 2, 1993
5AC1
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BU of 5ac1 by Molmil
Sheep aldehyde dehydrogenase 1A1 with duocarmycin analog inhibitor
Descriptor: 1-[(1S)-1-methyl-5-oxidanyl-1,2-dihydrobenzo[e]indol-3-yl]hexan-1-one, MAGNESIUM ION, RETINAL DEHYDROGENASE 1, ...
Authors:Koch, M.F, Harteis, S, Blank, I.D, Pestel, G, Tietze, L.F, Ochsenfeld, C, Schneider, S, Sieber, S.A.
Deposit date:2015-08-11
Release date:2015-08-26
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.08 Å)
Cite:Structural, Biochemical, and Computational Studies Reveal the Mechanism of Selective Aldehyde Dehydrogenase 1A1 Inhibition by Cytotoxic Duocarmycin Analogues.
Angew.Chem.Int.Ed.Engl., 54, 2015
8BIP
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BU of 8bip by Molmil
Structure of a yeast 80S ribosome-bound N-Acetyltransferase B complex
Descriptor: 25S rRNA, 5.8S rRNA, 5S rRNA, ...
Authors:Knorr, A.G, Mackens-Kiani, T, Musial, J, Berninghausen, O, Becker, T, Beatrix, B, Beckmann, R.
Deposit date:2022-11-02
Release date:2023-02-08
Last modified:2024-07-24
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:The dynamic architecture of Map1- and NatB-ribosome complexes coordinates the sequential modifications of nascent polypeptide chains.
Plos Biol., 21, 2023
3P8M
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BU of 3p8m by Molmil
Human dynein light chain (DYNLL2) in complex with an in vitro evolved peptide dimerized by leucine zipper
Descriptor: Dynein light chain 2, General control protein GCN4
Authors:Rapali, P, Radnai, L, Suveges, D, Hetenyi, C, Harmat, V, Tolgyesi, F, Wahlgren, W.Y, Katona, G, Nyitray, L, Pal, G.
Deposit date:2010-10-14
Release date:2011-08-31
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Directed evolution reveals the binding motif preference of the LC8/DYNLL hub protein and predicts large numbers of novel binders in the human proteome.
Plos One, 6, 2011
8BJQ
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BU of 8bjq by Molmil
Structure of a yeast 80S ribosome-bound N-Acetyltransferase B complex
Descriptor: 25S rRNA, 5.8S rRNA, 5S rRNA, ...
Authors:Knorr, A.G, Mackens-Kiani, T, Musial, J, Berninghausen, O, Becker, T, Beatrix, B, Beckmann, R.
Deposit date:2022-11-05
Release date:2023-02-08
Last modified:2024-07-24
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:The dynamic architecture of Map1- and NatB-ribosome complexes coordinates the sequential modifications of nascent polypeptide chains.
Plos Biol., 21, 2023
6G04
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BU of 6g04 by Molmil
NMR Solution Structure of Yeast TSR2(1-152) in Complex with S26A(100-119)
Descriptor: 40S ribosomal protein S26-A, Pre-rRNA-processing protein TSR2
Authors:Michel, E, Schuetz, S, Damberger, F.F, Allain, F.H.-T, Panse, V.G.
Deposit date:2018-03-16
Release date:2018-09-19
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Molecular basis for disassembly of an importin:ribosomal protein complex by the escortin Tsr2.
Nat Commun, 9, 2018
2TSC
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BU of 2tsc by Molmil
STRUCTURE, MULTIPLE SITE BINDING, AND SEGMENTAL ACCOMODATION IN THYMIDYLATE SYNTHASE ON BINDING D/UMP AND AN ANTI-FOLATE
Descriptor: 10-PROPARGYL-5,8-DIDEAZAFOLIC ACID, 2'-DEOXYURIDINE 5'-MONOPHOSPHATE, THYMIDYLATE SYNTHASE
Authors:Montfort, W.R, Stroud, R.M.
Deposit date:1991-07-03
Release date:1991-10-15
Last modified:2024-06-05
Method:X-RAY DIFFRACTION (1.97 Å)
Cite:Structure, multiple site binding, and segmental accommodation in thymidylate synthase on binding dUMP and an anti-folate.
Biochemistry, 29, 1990

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