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1EET
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BU of 1eet by Molmil
HIV-1 REVERSE TRANSCRIPTASE IN COMPLEX WITH THE INHIBITOR MSC204
Descriptor: 1-(5-BROMO-PYRIDIN-2-YL)-3-[2-(6-FLUORO-2-HYDROXY-3-PROPIONYL-PHENYL)-CYCLOPROPYL]-UREA, HIV-1 REVERSE TRANSCRIPTASE
Authors:Hogberg, M, Sahlberg, C, Engelhardt, P, Noreen, R, Kangasmetsa, J, Johansson, N.G, Oberg, B, Vrang, L, Zhang, H, Sahlberg, B.L, Unge, T, Lovgren, S, Fridborg, K, Backbro, K.
Deposit date:2000-02-03
Release date:2001-02-07
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.73 Å)
Cite:Urea-PETT compounds as a new class of HIV-1 reverse transcriptase inhibitors. 3. Synthesis and further structure-activity relationship studies of PETT analogues.
J.Med.Chem., 42, 1999
1EHT
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BU of 1eht by Molmil
THEOPHYLLINE-BINDING RNA IN COMPLEX WITH THEOPHYLLINE, NMR, 10 STRUCTURES
Descriptor: THEOPHYLLINE, THEOPHYLLINE-BINDING RNA
Authors:Zimmermann, G.R, Pardi, A.
Deposit date:1997-03-20
Release date:1997-12-24
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Interlocking structural motifs mediate molecular discrimination by a theophylline-binding RNA.
Nat.Struct.Biol., 4, 1997
7OLB
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BU of 7olb by Molmil
Crystal structure of Pab-AGOG, an 8-oxoguanine DNA glycosylase from Pyrococcus abyssi
Descriptor: 1,2-ETHANEDIOL, CHLORIDE ION, CITRIC ACID, ...
Authors:Coste, F, Goffinont, S, Flament, D, Castaing, B.
Deposit date:2021-05-19
Release date:2022-06-01
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.1 Å)
Cite:Structural and functional determinants of the archaeal 8-oxoguanine-DNA glycosylase AGOG for DNA damage recognition and processing.
Nucleic Acids Res., 50, 2022
1EGZ
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BU of 1egz by Molmil
CELLULASE CEL5 FROM ERWINIA CHRYSANTHEMI, A FAMILY GH 5-2 ENZYME
Descriptor: CALCIUM ION, ENDOGLUCANASE Z
Authors:Czjzek, M, El Hassouni, M, Py, B, Barras, F.
Deposit date:1999-03-18
Release date:1999-03-26
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Type II protein secretion in gram-negative pathogenic bacteria: the study of the structure/secretion relationships of the cellulase Cel5 (formerly EGZ) from Erwinia chrysanthemi
J.Mol.Biol., 310, 2001
9FMD
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BU of 9fmd by Molmil
Integrative model of the human post-catalytic spliceosome (P-complex)
Descriptor: 116 kDa U5 small nuclear ribonucleoprotein component, ADENOSINE-5'-TRIPHOSPHATE, ATP-dependent RNA helicase DHX8, ...
Authors:Rothe, P, Plaschka, C, Vorlaender, M.K.
Deposit date:2024-06-05
Release date:2024-07-10
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Mechanism for the initiation of spliceosome disassembly.
Nature, 2024
4TXD
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BU of 4txd by Molmil
Crystal structure of Thermofilum pendens Csc2
Descriptor: Csc2, ZINC ION
Authors:Hrle, A, Conti, E.
Deposit date:2014-07-03
Release date:2014-08-27
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (1.818 Å)
Cite:Structural analyses of the CRISPR protein Csc2 reveal the RNA-binding interface of the type I-D Cas7 family.
Rna Biol., 11, 2014
1ET4
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BU of 1et4 by Molmil
CRYSTAL STRUCTURE OF A VITAMIN B12 BINDING RNA APTAMER WITH LIGAND AT 2.3 A
Descriptor: CYANOCOBALAMIN, RNA APTAMER, 35-MER
Authors:Sussman, D, Wilson, C.
Deposit date:2000-04-12
Release date:2000-11-13
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:A water channel in the core of the vitamin B(12) RNA aptamer.
Structure Fold.Des., 8, 2000
8G23
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BU of 8g23 by Molmil
Structure of Ternary Complex of cGAS with dsDNA and Bound pppIpA
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Cyclic GMP-AMP synthase, MAGNESIUM ION, ...
Authors:Wu, S, Sohn, J.
Deposit date:2023-02-03
Release date:2024-05-22
Last modified:2024-05-29
Method:X-RAY DIFFRACTION (2.71 Å)
Cite:The structural basis for 2'-5'/3'-5'-cGAMP synthesis by cGAS.
Nat Commun, 15, 2024
1EAN
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BU of 1ean by Molmil
THE RUNX1 Runt domain at 1.70A resolution: A structural switch and specifically bound chloride ions modulate DNA binding
Descriptor: CHLORIDE ION, RUNT-RELATED TRANSCRIPTION FACTOR 1
Authors:Backstrom, S, Wolf-Watz, M, Grundstrom, C, Hard, T, Grundstrom, T, Sauer, U.H.
Deposit date:2001-07-13
Release date:2002-09-12
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:The Runx1 Runt Domain at 1.25 A Resolution: A Structural Switch and Specifically Bound Chloride Ions Modulate DNA Binding
J.Mol.Biol., 322, 2002
4TUS
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BU of 4tus by Molmil
Human DNA polymerase beta inserting dCMPNPP opposite the 5'G of cisplatin crosslinked Gs (Pt-GG2) WITH MANGANESE IN THE ACTIVE SITE.
Descriptor: 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]cytidine, Cisplatin, DNA (5'-D(*CP*CP*CP*AP*CP*GP*GP*CP*CP*CP*AP*TP*CP*AP*CP*C)-3'), ...
Authors:Koag, M.C, Lee, S.
Deposit date:2014-06-24
Release date:2014-10-01
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.42 Å)
Cite:Structural Basis for the Inefficient Nucleotide Incorporation Opposite Cisplatin-DNA Lesion by Human DNA Polymerase beta.
J.Biol.Chem., 289, 2014
1ESD
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BU of 1esd by Molmil
THE MOLECULAR MECHANISM OF ENANTIORECOGNITION BY ESTERASES
Descriptor: ESTERASE, METHYLPHOSPHONIC ACID ESTER GROUP
Authors:Wei, Y, Schottel, J.L, Derewenda, U, Swenson, L, Patkar, S, Derewenda, Z.S.
Deposit date:1994-10-07
Release date:1995-10-15
Last modified:2024-06-05
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:A novel variant of the catalytic triad in the Streptomyces scabies esterase.
Nat.Struct.Biol., 2, 1995
4TUQ
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BU of 4tuq by Molmil
Human DNA polymerase beta inserting dCMPNPP opposite GG template (GG0b).
Descriptor: 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]cytidine, DNA (5'-D(*CP*CP*CP*AP*CP*GP*GP*CP*CP*CP*AP*TP*CP*AP*CP*C)-3'), DNA (5'-D(*GP*GP*TP*GP*AP*TP*GP*GP*GP*C)-3'), ...
Authors:Koag, M.C, Lee, S.
Deposit date:2014-06-24
Release date:2014-10-01
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.367 Å)
Cite:Structural Basis for the Inefficient Nucleotide Incorporation Opposite Cisplatin-DNA Lesion by Human DNA Polymerase beta.
J.Biol.Chem., 289, 2014
7OU3
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BU of 7ou3 by Molmil
Crystal structure of Tga-AGOG, an 8-oxoguanine DNA glycosylase from Thermococcus gammatolerans
Descriptor: CHLORIDE ION, GLYCEROL, N-glycosylase/DNA lyase
Authors:Coste, F, Confalonieri, F, Castaing, B.
Deposit date:2021-06-11
Release date:2022-06-22
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.49 Å)
Cite:Structural and functional determinants of the archaeal 8-oxoguanine-DNA glycosylase AGOG for DNA damage recognition and processing.
Nucleic Acids Res., 50, 2022
1EAW
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BU of 1eaw by Molmil
Crystal structure of the MTSP1 (matriptase)-BPTI (aprotinin) complex
Descriptor: PANCREATIC TRYPSIN INHIBITOR, SUPPRESSOR OF TUMORIGENICITY 14
Authors:Friedrich, R, Bode, W.
Deposit date:2001-07-17
Release date:2002-01-28
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.93 Å)
Cite:Catalytic Domain Structures of Mt-Sp1/Matriptase, a Matrix-Degrading Transmembrane Serine Proteinase.
J.Biol.Chem., 277, 2002
8H50
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BU of 8h50 by Molmil
Crystal structure of carboxyspermidine dehydrogenase from Helicobacter pylori in space group C2221
Descriptor: Saccharopine dehydrogenase
Authors:Ko, K.Y, Park, S.C, Cho, S.Y, Yoon, S.I.
Deposit date:2022-10-11
Release date:2022-11-09
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structural analysis of carboxyspermidine dehydrogenase from Helicobacter pylori.
Biochem.Biophys.Res.Commun., 635, 2022
8H4Z
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BU of 8h4z by Molmil
Crystal structure of carboxyspermidine dehydrogenase from Helicobacter pylori in space group P21212
Descriptor: Saccharopine dehydrogenase
Authors:Ko, K.Y, Park, S.C, Cho, S.Y, Yoon, S.I.
Deposit date:2022-10-11
Release date:2022-11-09
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural analysis of carboxyspermidine dehydrogenase from Helicobacter pylori.
Biochem.Biophys.Res.Commun., 635, 2022
8H52
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BU of 8h52 by Molmil
Crystal structure of Helicobacter pylori carboxyspermidine dehydrogenase in complex with NADP
Descriptor: NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, Saccharopine dehydrogenase
Authors:Ko, K.Y, Park, S.C, Cho, S.Y, Yoon, S.I.
Deposit date:2022-10-11
Release date:2022-11-09
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Structural analysis of carboxyspermidine dehydrogenase from Helicobacter pylori.
Biochem.Biophys.Res.Commun., 635, 2022
7OPK
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BU of 7opk by Molmil
Crystal structure of C. thermophilum Xrn2
Descriptor: 5'-3' exoribonuclease, MAGNESIUM ION
Authors:Overbeck, J.H, Sprangers, R.
Deposit date:2021-06-01
Release date:2022-07-06
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (3 Å)
Cite:Observation of conformational changes that underlie the catalytic cycle of Xrn2.
Nat.Chem.Biol., 18, 2022
8HIJ
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BU of 8hij by Molmil
The 5-MTHF-bound BRIL-SLC19A1/Fab/Nb ternary complex
Descriptor: Anti-BRIL Fab heavy chain, Anti-BRIL Fab light chain, Anti-Fab nanobody, ...
Authors:Zhang, Z, Dang, Y.
Deposit date:2022-11-20
Release date:2022-12-21
Last modified:2023-01-11
Method:ELECTRON MICROSCOPY (3.54 Å)
Cite:Molecular mechanism of substrate recognition by folate transporter SLC19A1.
Cell Discov, 8, 2022
8HEH
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BU of 8heh by Molmil
Crystal structure of GCN5-related N-acetyltransferase 05790
Descriptor: COENZYME A, GLYCEROL, GNAT family N-acetyltransferase
Authors:Xu, M.X, Ran, T.T, Wang, W.
Deposit date:2022-11-08
Release date:2022-12-21
Last modified:2024-05-29
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Crystal structure of prodigiosin binding protein PgbP, a GNAT family protein, in Serratia marcescens FS14.
Biochem.Biophys.Res.Commun., 640, 2022
4V4V
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BU of 4v4v by Molmil
Structure of a pre-translocational E. coli ribosome obtained by fitting atomic models for RNA and protein components into cryo-EM map EMD-1056
Descriptor: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal subunit protein S10, ...
Authors:Mitra, K, Frank, J.
Deposit date:2006-05-09
Release date:2014-07-09
Last modified:2024-02-28
Method:ELECTRON MICROSCOPY (15 Å)
Cite:Elongation arrest by SecM via a cascade of ribosomal RNA rearrangements
Mol.Cell, 22, 2006
1E59
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BU of 1e59 by Molmil
E.coli cofactor-dependent phosphoglycerate mutase complexed with vanadate
Descriptor: CHLORIDE ION, PHOSPHOGLYCERATE MUTASE, TETRAMETAVANADATE
Authors:Bond, C.S, Hunter, W.N.
Deposit date:2000-07-19
Release date:2002-02-05
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:Mechanistic Implications for Escherichia Coli Cofactor-Dependent Phosphoglycerate Mutase Based on the High-Resolution Crystal Structure of a Vanadate Complex.
J.Mol.Biol., 316, 2002
1ELV
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BU of 1elv by Molmil
CRYSTAL STRUCTURE OF THE CATALYTIC DOMAIN OF HUMAN COMPLEMENT C1S PROTEASE
Descriptor: 2-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-ETHANESULFONIC ACID, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, COMPLEMENT C1S COMPONENT, ...
Authors:Gaboriaud, C, Rossi, V, Bally, I, Arlaud, G, Fontecilla-Camps, J.-C.
Deposit date:2000-03-14
Release date:2001-03-14
Last modified:2021-11-03
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Crystal structure of the catalytic domain of human complement c1s: a serine protease with a handle.
EMBO J., 19, 2000
1ENW
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BU of 1enw by Molmil
ELONGATION FACTOR TFIIS DOMAIN II
Descriptor: TRANSCRIPTION ELONGATION FACTOR S-II
Authors:Morin, P.E, Awrey, D.E, Edwards, A.M, Arrowsmith, C.H.
Deposit date:2000-03-21
Release date:2000-04-12
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Elongation factor TFIIS contains three structural domains: solution structure of domain II.
Proc.Natl.Acad.Sci.USA, 93, 1996
4V4W
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Structure of a SecM-stalled E. coli ribosome complex obtained by fitting atomic models for RNA and protein components into cryo-EM map EMD-1143
Descriptor: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal subunit protein S10, ...
Authors:Mitra, K, Frank, J.
Deposit date:2006-05-09
Release date:2014-07-09
Last modified:2024-02-28
Method:ELECTRON MICROSCOPY (15 Å)
Cite:Elongation arrest by SecM via a cascade of ribosomal RNA rearrangements
Mol.Cell, 22, 2006

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