7D8B
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![BU of 7d8b by Molmil](/molmil-images/mine/7d8b) | Engineering Disulphide-Free Autonomous Antibody VH Domains to modulate intracellular pathways | Descriptor: | Eukaryotic translation initiation factor 4E, VH-S4 | Authors: | Frosi, Y, Lin, Y.C, Jiang, S, Brown, C.J. | Deposit date: | 2020-10-07 | Release date: | 2021-08-25 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.46 Å) | Cite: | Engineering an autonomous VH domain to modulate intracellular pathways and to interrogate the eIF4F complex. Nat Commun, 13, 2022
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6LLZ
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2GH2
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6LMY
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![BU of 6lmy by Molmil](/molmil-images/mine/6lmy) | Crystal structure of DUSP22 mutant_C88S/S93A | Descriptor: | Dual specificity protein phosphatase 22, PHOSPHATE ION | Authors: | Lai, C.H, Lyu, P.C. | Deposit date: | 2019-12-27 | Release date: | 2020-10-28 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Structural Insights into the Active Site Formation of DUSP22 in N-loop-containing Protein Tyrosine Phosphatases. Int J Mol Sci, 21, 2020
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6OQP
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![BU of 6oqp by Molmil](/molmil-images/mine/6oqp) | U-AITx-Ate1 | Descriptor: | SER-LYS-TRP-ILE-CYS-ALA-ASN-ARG-SER-VAL-CYS-PRO-ILE | Authors: | Elnahriry, K.A, Wai, D.C.C, Norton, R.S. | Deposit date: | 2019-04-28 | Release date: | 2019-07-31 | Last modified: | 2023-06-14 | Method: | SOLUTION NMR | Cite: | Structural and functional characterisation of a novel peptide from the Australian sea anemone Actinia tenebrosa. Toxicon, 168, 2019
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2GHW
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![BU of 2ghw by Molmil](/molmil-images/mine/2ghw) | Crystal structure of SARS spike protein receptor binding domain in complex with a neutralizing antibody, 80R | Descriptor: | CHLORIDE ION, Spike glycoprotein, anti-sars scFv antibody, ... | Authors: | Hwang, W.C, Lin, Y, Santelli, E, Sui, J, Jaroszewski, L, Stec, B, Farzan, M, Marasco, W.A, Liddington, R.C. | Deposit date: | 2006-03-27 | Release date: | 2006-09-19 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structural basis of neutralization by a human anti-severe acute respiratory syndrome spike protein antibody, 80R. J.Biol.Chem., 281, 2006
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7Z1X
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7YTO
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6LOT
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![BU of 6lot by Molmil](/molmil-images/mine/6lot) | Crystal structure of DUSP22 mutant_N128D | Descriptor: | Dual specificity protein phosphatase 22, SULFATE ION | Authors: | Lai, C.H, Lyu, P.C. | Deposit date: | 2020-01-07 | Release date: | 2020-10-28 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.69 Å) | Cite: | Structural Insights into the Active Site Formation of DUSP22 in N-loop-containing Protein Tyrosine Phosphatases. Int J Mol Sci, 21, 2020
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2G8G
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![BU of 2g8g by Molmil](/molmil-images/mine/2g8g) | Structurally mapping the diverse phenotype of Adeno-Associated Virus serotype 4 | Descriptor: | 2'-DEOXYADENOSINE-5'-MONOPHOSPHATE, Capsid | Authors: | Govindasamy, L, Padron, E, McKenna, R, Muzyczka, N, Chiorini, J.A, Agbandje-McKenna, M. | Deposit date: | 2006-03-02 | Release date: | 2007-01-02 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | Structurally mapping the diverse phenotype of adeno-associated virus serotype 4. J.Virol., 80, 2006
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6LZG
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![BU of 6lzg by Molmil](/molmil-images/mine/6lzg) | Structure of novel coronavirus spike receptor-binding domain complexed with its receptor ACE2 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme 2, Spike protein S1, ... | Authors: | Wang, Q.H, Song, H, Qi, J.X. | Deposit date: | 2020-02-19 | Release date: | 2020-03-18 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Structural and Functional Basis of SARS-CoV-2 Entry by Using Human ACE2. Cell, 181, 2020
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2GFP
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![BU of 2gfp by Molmil](/molmil-images/mine/2gfp) | Structure of the Multidrug Transporter EmrD from Escherichia coli | Descriptor: | Multidrug resistance protein D | Authors: | Yin, Y, He, X, Szewczyk, P, Nguyen, T, Chang, G. | Deposit date: | 2006-03-22 | Release date: | 2006-05-16 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (3.5 Å) | Cite: | Structure of the multidrug transporter EmrD from Escherichia coli Science, 312, 2006
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6LU8
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![BU of 6lu8 by Molmil](/molmil-images/mine/6lu8) | Cryo-EM structure of a human pre-60S ribosomal subunit - state A | Descriptor: | 28S rRNA, 5.8S rRNA, 5S rRNA, ... | Authors: | Liang, X, Zuo, M, Zhang, Y, Li, N, Ma, C, Dong, M, Gao, N. | Deposit date: | 2020-01-26 | Release date: | 2020-08-26 | Method: | ELECTRON MICROSCOPY (3.13 Å) | Cite: | Structural snapshots of human pre-60S ribosomal particles before and after nuclear export. Nat Commun, 11, 2020
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4GGK
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![BU of 4ggk by Molmil](/molmil-images/mine/4ggk) | Crystal structure of Zucchini from mouse (mZuc / PLD6 / MitoPLD) bound to tungstate | Descriptor: | Mitochondrial cardiolipin hydrolase, TUNGSTATE(VI)ION, ZINC ION | Authors: | Ipsaro, J.J, Haase, A.D, Hannon, G.J, Joshua-Tor, L. | Deposit date: | 2012-08-06 | Release date: | 2012-10-10 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | The structural biochemistry of Zucchini implicates it as a nuclease in piRNA biogenesis. Nature, 491, 2012
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7ZG3
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![BU of 7zg3 by Molmil](/molmil-images/mine/7zg3) | Structure of the mouse 8-oxoguanine DNA Glycosylase mOGG1 in complex with ligand TH011228 | Descriptor: | N-glycosylase/DNA lyase, NICKEL (II) ION, ~{N}-[(1~{S})-1,2,2-trimethylcyclopropyl]pyrrolo[1,2-c]pyrimidine-3-carboxamide | Authors: | Davies, J.R, Scaletti, E, Stenmark, P. | Deposit date: | 2022-04-01 | Release date: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structure of the mouse 8-oxoguanine DNA Glycosylase mOGG1 in complex with ligand TH011228 To Be Published
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7YW9
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![BU of 7yw9 by Molmil](/molmil-images/mine/7yw9) | Crystal structure of the triple mutant CmnC-L136Q,S138G,D249Y in complex with alpha-KG | Descriptor: | ACETATE ION, CmnC, D-ARGININE, ... | Authors: | Huang, S.J, Hsiao, Y.H, Lin, E.C, Hsiao, P.Y, Chang, C.Y. | Deposit date: | 2022-08-22 | Release date: | 2023-08-30 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (1.76 Å) | Cite: | Crystal structure of the alpha-ketoglutarate-dependent non-heme iron oxygenase CmnC in capreomycin biosynthesis and its engineering to catalyze hydroxylation of the substrate enantiomer. Front Chem, 10, 2022
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2GHQ
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5IRN
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4ETU
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4GJS
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![BU of 4gjs by Molmil](/molmil-images/mine/4gjs) | Streptavidin-K121H | Descriptor: | Rhodium, Streptavidin, trichloro{(1,2,3,4,5-eta)-1,2,3,4-tetramethyl-5-[2-({5-[(3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl]pentanoyl}amino)ethyl]cyclopentadienyl}rhodium(1+) | Authors: | Heinisch, T, Schirmer, T. | Deposit date: | 2012-08-10 | Release date: | 2013-02-13 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | A dual anchoring strategy for the localization and activation of artificial metalloenzymes based on the biotin-streptavidin technology. J.Am.Chem.Soc., 135, 2013
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5IS2
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7DDX
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![BU of 7ddx by Molmil](/molmil-images/mine/7ddx) | Crystal structure of KANK1 S1179F mutant in complex wtih eIF4A1 | Descriptor: | Eukaryotic initiation factor 4A-I, GLYCEROL, KN motif and ankyrin repeat domains 1, ... | Authors: | Pan, W, Xu, Y, Wei, Z. | Deposit date: | 2020-10-30 | Release date: | 2021-09-08 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Nephrotic-syndrome-associated mutation of KANK2 induces pathologic binding competition with physiological interactor KIF21A. J.Biol.Chem., 297, 2021
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7Z6O
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![BU of 7z6o by Molmil](/molmil-images/mine/7z6o) | X-Ray studies of Ku70/80 reveal the binding site for IP6 | Descriptor: | DNA (5'-D(*GP*TP*TP*TP*TP*TP*AP*GP*TP*TP*TP*AP*T)-3'), DNA (5'-D(P*AP*AP*AP*TP*AP*AP*AP*CP*TP*AP*AP*AP*AP*AP*C)-3'), INOSITOL HEXAKISPHOSPHATE, ... | Authors: | Varela, P.F, Charbonnier, J.B. | Deposit date: | 2022-03-14 | Release date: | 2023-08-30 | Last modified: | 2023-12-06 | Method: | X-RAY DIFFRACTION (3.7 Å) | Cite: | Structural and functional basis of inositol hexaphosphate stimulation of NHEJ through stabilization of Ku-XLF interaction. Nucleic Acids Res., 51, 2023
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2G81
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![BU of 2g81 by Molmil](/molmil-images/mine/2g81) | Crystal Structure of the Bowman-Birk Inhibitor from Vigna unguiculata Seeds in Complex with Beta-trypsin at 1.55 Angstrons Resolution | Descriptor: | 1,2-ETHANEDIOL, ACETIC ACID, Bowman-Birk type seed trypsin and chymotrypsin inhibitor, ... | Authors: | Freitas, S.M, Barbosa, J.A.R.G, Paulino, L.S, Teles, R.C.L, Esteves, G.F, Ventura, M.M. | Deposit date: | 2006-03-01 | Release date: | 2007-01-02 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.55 Å) | Cite: | Crystal Structure of the Bowman-Birk Inhibitor from Vigna unguiculata Seeds in Complex with {beta}-Trypsin at 1.55 A Resolution and Its Structural Properties in Association with Proteinases Biophys.J., 92, 2007
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5ISK
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![BU of 5isk by Molmil](/molmil-images/mine/5isk) | |