2HP6
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![BU of 2hp6 by Molmil](/molmil-images/mine/2hp6) | Crystal structure of the OXA-10 W154A mutant at pH 7.5 | Descriptor: | Beta-lactamase PSE-2, SULFATE ION | Authors: | Kerff, F, Falzone, C, Herman, R, Sauvage, E, Charlier, P. | Deposit date: | 2006-07-17 | Release date: | 2007-07-03 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Critical role of tryptophan 154 for the activity and stability of class D beta-lactamases. Biochemistry, 48, 2009
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2HP9
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![BU of 2hp9 by Molmil](/molmil-images/mine/2hp9) | Crystal Structure of the OXA-10 W154A mutant at pH 6.0 | Descriptor: | Beta-lactamase PSE-2, SULFATE ION | Authors: | Kerff, F, Falzone, C, Herman, R, Sauvage, E, Charlier, P. | Deposit date: | 2006-07-17 | Release date: | 2007-07-03 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Critical role of tryptophan 154 for the activity and stability of class D beta-lactamases. Biochemistry, 48, 2009
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2I72
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![BU of 2i72 by Molmil](/molmil-images/mine/2i72) | AmpC beta-lactamase in complex with 5-diformylaminomethyl-benzo[b]thiophen-2-boronic acid | Descriptor: | Beta-lactamase, {5-[(DIFORMYLAMINO)METHYL]-1-BENZOTHIEN-2-YL}BORONIC ACID | Authors: | Venturelli, A, Cancian, L, Tondi, D, Morandi, F, Cannazza, G, Segatore, B, Prati, F, Amicosante, G, Shoichet, B.K, Costi, M.P. | Deposit date: | 2006-08-30 | Release date: | 2007-09-11 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Optimizing Cell Permeation of an Antibiotic Resistance Inhibitor for Improved Efficacy J.Med.Chem., 50, 2007
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2H5Y
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![BU of 2h5y by Molmil](/molmil-images/mine/2h5y) | Crystallographic structure of the Molybdate-Binding Protein of Xanthomonas citri at 1.7 Ang resolution bound to molybdate | Descriptor: | MOLYBDATE ION, Molybdate-binding periplasmic protein, SULFATE ION | Authors: | Balan, A, Santacruz, C.P, Ferreira, L.C.S, Barbosa, J.A.R.G. | Deposit date: | 2006-05-29 | Release date: | 2007-06-05 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Crystallization, data collection and phasing of the molybdate-binding protein of the phytopathogen Xanthomonas axonopodis pv. citri Acta Crystallogr.,Sect.F, 62, 2006
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2HP5
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![BU of 2hp5 by Molmil](/molmil-images/mine/2hp5) | Crystal Structure of the OXA-10 W154G mutant at pH 7.0 | Descriptor: | Beta-lactamase PSE-2, COBALT (II) ION, SULFATE ION | Authors: | Kerff, F, Falzone, C, Herman, R, Sauvage, E, Charlier, P. | Deposit date: | 2006-07-17 | Release date: | 2007-07-03 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Critical role of tryptophan 154 for the activity and stability of class D beta-lactamases. Biochemistry, 48, 2009
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4IJG
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![BU of 4ijg by Molmil](/molmil-images/mine/4ijg) | Crystal structure of monomeric bacteriophytochrome | Descriptor: | 3-[2-[(Z)-[3-(2-carboxyethyl)-5-[(Z)-(4-ethenyl-3-methyl-5-oxidanylidene-pyrrol-2-ylidene)methyl]-4-methyl-pyrrol-1-ium -2-ylidene]methyl]-5-[(Z)-[(3E)-3-ethylidene-4-methyl-5-oxidanylidene-pyrrolidin-2-ylidene]methyl]-4-methyl-1H-pyrrol-3- yl]propanoic acid, Bacteriophytochrome, DI(HYDROXYETHYL)ETHER, ... | Authors: | Auldridge, M.E. | Deposit date: | 2012-12-21 | Release date: | 2013-12-25 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.701 Å) | Cite: | Origins of fluorescence in evolved bacteriophytochromes. J.Biol.Chem., 289, 2014
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4II0
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![BU of 4ii0 by Molmil](/molmil-images/mine/4ii0) | |
4LH8
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![BU of 4lh8 by Molmil](/molmil-images/mine/4lh8) | Triazine hydrolase from Arthobacter aurescens modified for maximum expression in E.coli | Descriptor: | Triazine hydrolase, ZINC ION | Authors: | Jackson, C.J, Coppin, C.W, Alexandrov, A, Wilding, M, Liu, J.-W, Ubels, J, Paks, M, Carr, P.D, Newman, J, Russell, R.J, Field, M, Weik, M, Oakeshott, J.G, Scott, C. | Deposit date: | 2013-07-01 | Release date: | 2014-05-21 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | 300-Fold increase in production of the Zn2+-dependent dechlorinase TrzN in soluble form via apoenzyme stabilization. Appl.Environ.Microbiol., 80, 2014
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4ILZ
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![BU of 4ilz by Molmil](/molmil-images/mine/4ilz) | Structural and kinetic study of an internal substrate binding site of dehaloperoxidase-hemoglobin A from Amphitrite ornata | Descriptor: | 2,4,6-TRIBROMOPHENOL, Dehaloperoxidase A, ISOPROPYL ALCOHOL, ... | Authors: | de Serrano, V.S, Zhao, J, Zhao, J, Franzen, S. | Deposit date: | 2013-01-01 | Release date: | 2013-03-27 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.91 Å) | Cite: | Structural and Kinetic Study of an Internal Substrate Binding Site in Dehaloperoxidase-Hemoglobin A from Amphitrite ornata. Biochemistry, 52, 2013
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4JX7
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![BU of 4jx7 by Molmil](/molmil-images/mine/4jx7) | Crystal structure of Pim1 kinase in complex with inhibitor 2-[(trans-4-aminocyclohexyl)amino]-4-{[3-(trifluoromethyl)phenyl]amino}pyrido[4,3-d]pyrimidin-5(6H)-one | Descriptor: | 2-[(trans-4-aminocyclohexyl)amino]-4-{[3-(trifluoromethyl)phenyl]amino}pyrido[4,3-d]pyrimidin-5(6H)-one, PIM1 consensus peptide, Serine/threonine-protein kinase pim-1 | Authors: | Lee, S.J, Han, B.G, Cho, J.W, Choi, J.S, Lee, J.K, Song, H.J, Koh, J.S, Lee, B.I. | Deposit date: | 2013-03-27 | Release date: | 2013-08-28 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Crystal structure of pim1 kinase in complex with a pyrido[4,3-d]pyrimidine derivative suggests a unique binding mode. Plos One, 8, 2013
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2BVU
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![BU of 2bvu by Molmil](/molmil-images/mine/2bvu) | |
4JX3
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![BU of 4jx3 by Molmil](/molmil-images/mine/4jx3) | Crystal structure of Pim1 kinase | Descriptor: | Serine/threonine-protein kinase pim-1 | Authors: | Lee, S.J, Han, B.G, Cho, J.W, Choi, J.S, Lee, J.K, Song, H.J, Koh, J.S, Lee, B.I. | Deposit date: | 2013-03-27 | Release date: | 2013-08-28 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Crystal structure of pim1 kinase in complex with a pyrido[4,3-d]pyrimidine derivative suggests a unique binding mode. Plos One, 8, 2013
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2B77
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![BU of 2b77 by Molmil](/molmil-images/mine/2b77) | Human transthyretin (TTR) complexed with Diflunisal analogues- TTR.2',4'-DICHLORO-4-HYDROXY-1,1'-BIPHENYL-3-CARBOXYLIC ACID | Descriptor: | 2',4'-DICHLORO-4-HYDROXY-1,1'-BIPHENYL-3-CARBOXYLIC ACID, Transthyretin | Authors: | Palaninathan, S.K, Kelly, J.W, Sacchettini, J.C. | Deposit date: | 2005-10-03 | Release date: | 2005-10-11 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Diflunisal analogues stabilize the native state of transthyretin. Potent inhibition of amyloidogenesis. J.Med.Chem., 47, 2004
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4GRX
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![BU of 4grx by Molmil](/molmil-images/mine/4grx) | Structure of an omega-aminotransferase from Paracoccus denitrificans | Descriptor: | Aminotransferase, DELTA-AMINO VALERIC ACID, SODIUM ION | Authors: | Rausch, C, Lerchner, A, Schiefner, A, Skerra, A. | Deposit date: | 2012-08-27 | Release date: | 2012-12-19 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Crystal structure of the omega-aminotransferase from Paracoccus denitrificans and its phylogenetic relationship with other class III aminotransferases that have biotechnological potential. Proteins, 81, 2013
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4O8G
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![BU of 4o8g by Molmil](/molmil-images/mine/4o8g) | Structure of Infrared Fluorescent Protein 1.4 | Descriptor: | 3-[2-[(Z)-[3-(2-carboxyethyl)-5-[(Z)-(4-ethenyl-3-methyl-5-oxidanylidene-pyrrol-2-ylidene)methyl]-4-methyl-pyrrol-1-ium -2-ylidene]methyl]-5-[(Z)-[(3E)-3-ethylidene-4-methyl-5-oxidanylidene-pyrrolidin-2-ylidene]methyl]-4-methyl-1H-pyrrol-3- yl]propanoic acid, 3-[2-[(Z)-[5-[(Z)-(4-ethenyl-3-methyl-5-oxidanylidene-pyrrol-2-ylidene)methyl]-3-(3-hydroxy-3-oxopropyl)-4-methyl-pyrrol-1-ium-2-ylidene]methyl]-5-[(Z)-[(3E,4R)-3-ethylidene-4-methyl-5-oxidanylidene-pyrrolidin-2-ylidene]methyl]-4-methyl-1H-pyrrol-3-yl]propanoic acid, Bacteriophytochrome | Authors: | Bhattacharya, S, Forest, K.T. | Deposit date: | 2013-12-27 | Release date: | 2014-10-01 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.652 Å) | Cite: | Origins of fluorescence in evolved bacteriophytochromes. J.Biol.Chem., 289, 2014
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4IHZ
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![BU of 4ihz by Molmil](/molmil-images/mine/4ihz) | |
2B9A
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![BU of 2b9a by Molmil](/molmil-images/mine/2b9a) | Human transthyretin (TTR) complexed with diflunisal analogues- TTR.3',5'-difluorobiphenyl-4-carboxylic acid | Descriptor: | 3',5'-DIFLUOROBIPHENYL-4-CARBOXYLIC ACID, Transthyretin | Authors: | Palaninathan, S.K, Kelly, J.W, Sacchettini, J.C. | Deposit date: | 2005-10-11 | Release date: | 2005-10-25 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.54 Å) | Cite: | Diflunisal Analogues Stabilize the Native State of Transthyretin. Potent Inhibition of Amyloidogenesis. J.Med.Chem., 47, 2004
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2F7I
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![BU of 2f7i by Molmil](/molmil-images/mine/2f7i) | Human transthyretin (TTR) complexed with diflunisal analogues- TTR. 2',6'-Difluorobiphenyl-4-carboxylic Acid | Descriptor: | 2',6'-DIFLUOROBIPHENYL-4-CARBOXYLIC ACID, Transthyretin | Authors: | Palaninathan, S.K, Kelly, J.W, Sacchettini, J.C. | Deposit date: | 2005-11-30 | Release date: | 2005-12-13 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Diflunisal Analogues Stabilize the Native State of Transthyretin. Potent Inhibition of Amyloidogenesis. J.Med.Chem., 47, 2004
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4KGE
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![BU of 4kge by Molmil](/molmil-images/mine/4kge) | Crystal structure of near-infrared fluorescent protein with an extended stokes shift, pH 4.5 | Descriptor: | CHLORIDE ION, TagRFP675, red fluorescent protein | Authors: | Malashkevich, V.N, Piatkevich, K, Almo, S.C, Verkhusha, V, New York Structural Genomics Research Consortium (NYSGRC) | Deposit date: | 2013-04-29 | Release date: | 2013-05-08 | Last modified: | 2023-12-06 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Extended Stokes shift in fluorescent proteins: chromophore-protein interactions in a near-infrared TagRFP675 variant. Sci Rep, 3, 2013
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4OID
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![BU of 4oid by Molmil](/molmil-images/mine/4oid) | Structural and kinetic bases for the metal preference of the M18 aminopeptidase from Pseudomonas aeruginosa | Descriptor: | Probable M18 family aminopeptidase 2 | Authors: | Nguyen, D.D, Pandian, R, Kim, D.D, Ha, S.C, Yoon, H.J, Kim, K.S, Yun, K.H, Kim, J.H, Kim, K.K. | Deposit date: | 2014-01-19 | Release date: | 2014-04-02 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structural and kinetic bases for the metal preference of the M18 aminopeptidase from Pseudomonas aeruginosa Biochem.Biophys.Res.Commun., 447, 2014
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4KGF
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![BU of 4kgf by Molmil](/molmil-images/mine/4kgf) | Crystal structure of near-infrared fluorescent protein with an extended stokes shift, ph 8.0 | Descriptor: | CHLORIDE ION, TagRFP675, red fluorescent protein | Authors: | Malashkevich, V.N, Piatkevich, K, Almo, S.C, Verkhusha, V, New York Structural Genomics Research Consortium (NYSGRC) | Deposit date: | 2013-04-29 | Release date: | 2013-05-08 | Last modified: | 2023-12-06 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Extended Stokes shift in fluorescent proteins: chromophore-protein interactions in a near-infrared TagRFP675 variant. Sci Rep, 3, 2013
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4J3Q
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![BU of 4j3q by Molmil](/molmil-images/mine/4j3q) | Crystal structure of truncated catechol oxidase from Aspergillus oryzae | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, COPPER (II) ION, ... | Authors: | Hakulinen, N, Gasparetti, C, Kaljunen, H, Rouvinen, J. | Deposit date: | 2013-02-06 | Release date: | 2013-11-27 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | The crystal structure of an extracellular catechol oxidase from the ascomycete fungus Aspergillus oryzae. J.Biol.Inorg.Chem., 18, 2013
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4OIW
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![BU of 4oiw by Molmil](/molmil-images/mine/4oiw) | Structural and kinetic bases for the metal preference of the M18 aminopeptidase from Pseudomonas aeruginosa | Descriptor: | Probable M18 family aminopeptidase 2, ZINC ION | Authors: | Nguyen, D.D, Pandian, R, Kim, D.D, Ha, S.C, Yoon, H.J, Kim, K.S, Yun, K.H, Kim, J.H, Kim, K.K. | Deposit date: | 2014-01-20 | Release date: | 2014-04-02 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.44 Å) | Cite: | Structural and kinetic bases for the metal preference of the M18 aminopeptidase from Pseudomonas aeruginosa Biochem.Biophys.Res.Commun., 447, 2014
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4NJR
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![BU of 4njr by Molmil](/molmil-images/mine/4njr) | Structural and kinetic bases for the metal preference of the M18 aminopeptidase from Pseudomonas aeruginosa | Descriptor: | CARBONATE ION, Probable M18 family aminopeptidase 2, ZINC ION | Authors: | Nguyen, D.D, Pandian, R, Kim, D.Y, Ha, S.C, Yun, K.H, Kim, K.S, Kim, J.H, Kim, K.K. | Deposit date: | 2013-11-11 | Release date: | 2014-04-02 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structural and kinetic bases for the metal preference of the M18 aminopeptidase from Pseudomonas aeruginosa Biochem.Biophys.Res.Commun., 447, 2014
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4PB5
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![BU of 4pb5 by Molmil](/molmil-images/mine/4pb5) | D-threo-3-hydroxyaspartate dehydratase H351A mutant complexed with L-erythro-3-hydroxyaspartate | Descriptor: | (3R)-3-hydroxy-L-aspartic acid, D-threo-3-hydroxyaspartate dehydratase, GLYCEROL, ... | Authors: | Yasutake, Y, Matsumoto, Y, Wada, M. | Deposit date: | 2014-04-11 | Release date: | 2015-03-11 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structural insights into the substrate stereospecificity of D-threo-3-hydroxyaspartate dehydratase from Delftia sp. HT23: a useful enzyme for the synthesis of optically pure L-threo- and D-erythro-3-hydroxyaspartate. Appl.Microbiol.Biotechnol., 99, 2015
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