4JX3
Crystal structure of Pim1 kinase
Summary for 4JX3
Entry DOI | 10.2210/pdb4jx3/pdb |
Related | 4JX7 |
Descriptor | Serine/threonine-protein kinase pim-1 (2 entities in total) |
Functional Keywords | human protein kinases, serine/threonine-protein kinase, atp binding, phosphorylation, transferase |
Biological source | Homo sapiens (human) |
Cellular location | Isoform 2: Cytoplasm. Isoform 1: Cell membrane: P11309 |
Total number of polymer chains | 1 |
Total formula weight | 37293.41 |
Authors | Lee, S.J.,Han, B.G.,Cho, J.W.,Choi, J.S.,Lee, J.K.,Song, H.J.,Koh, J.S.,Lee, B.I. (deposition date: 2013-03-27, release date: 2013-08-28, Last modification date: 2023-09-20) |
Primary citation | Lee, S.J.,Han, B.G.,Cho, J.W.,Choi, J.S.,Lee, J.,Song, H.J.,Koh, J.S.,Lee, B.I. Crystal structure of pim1 kinase in complex with a pyrido[4,3-d]pyrimidine derivative suggests a unique binding mode. Plos One, 8:e70358-e70358, 2013 Cited by PubMed: 23936194DOI: 10.1371/journal.pone.0070358 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.5 Å) |
Structure validation
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