6PLG
| Crystal structure of human PHGDH complexed with Compound 15 | Descriptor: | (2S)-(4-{3-[(4,5-dichloro-1-methyl-1H-indole-2-carbonyl)amino]oxetan-3-yl}phenyl)(pyridin-3-yl)acetic acid, D-3-phosphoglycerate dehydrogenase, D-MALATE | Authors: | Olland, A, Lakshminarasimhan, D, White, A, Suto, R.K. | Deposit date: | 2019-06-30 | Release date: | 2019-07-24 | Last modified: | 2019-09-04 | Method: | X-RAY DIFFRACTION (2.93 Å) | Cite: | Inhibition of 3-phosphoglycerate dehydrogenase (PHGDH) by indole amides abrogates de novo serine synthesis in cancer cells. Bioorg.Med.Chem.Lett., 29, 2019
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5AOV
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3GVX
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4NU6
| Crystal Structure of PTDH R301K | Descriptor: | NICOTINAMIDE-ADENINE-DINUCLEOTIDE, Phosphonate dehydrogenase, SULFATE ION | Authors: | Nair, S.K, Chekan, J.R. | Deposit date: | 2013-12-03 | Release date: | 2014-03-12 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.65 Å) | Cite: | Chemical rescue and inhibition studies to determine the role of arg301 in phosphite dehydrogenase. Plos One, 9, 2014
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6PEX
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6PLF
| Crystal structure of human PHGDH complexed with Compound 1 | Descriptor: | 1,2-ETHANEDIOL, 4-{(1S)-1-[(5-chloro-6-{[(5S)-2-oxo-1,3-oxazolidin-5-yl]methoxy}-1H-indole-2-carbonyl)amino]-2-hydroxyethyl}benzoic acid, D-3-phosphoglycerate dehydrogenase | Authors: | Olland, A, Lakshminarasimhan, D, White, A, Suto, R.K. | Deposit date: | 2019-06-30 | Release date: | 2019-07-24 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Inhibition of 3-phosphoglycerate dehydrogenase (PHGDH) by indole amides abrogates de novo serine synthesis in cancer cells. Bioorg.Med.Chem.Lett., 29, 2019
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3FN4
| Apo-form of NAD-dependent formate dehydrogenase from bacterium Moraxella sp.C-1 in closed conformation | Descriptor: | GLYCEROL, NAD-dependent formate dehydrogenase, SULFATE ION | Authors: | Shabalin, I.G, Polyakov, K.M, Filippova, E.V, Dorovatovskiy, P.V, Tikhonova, T.V, Sadykhov, E.G, Tishkov, V.I, Popov, V.O. | Deposit date: | 2008-12-23 | Release date: | 2009-12-01 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.96 Å) | Cite: | Structures of the apo and holo forms of formate dehydrogenase from the bacterium Moraxella sp. C-1: towards understanding the mechanism of the closure of the interdomain cleft Acta Crystallogr.,Sect.D, 65, 2009
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4NJO
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4NU5
| Crystal Structure of PTDH R301A | Descriptor: | NICOTINAMIDE-ADENINE-DINUCLEOTIDE, Phosphonate dehydrogenase | Authors: | Nair, S.K, Chekan, J.R. | Deposit date: | 2013-12-03 | Release date: | 2014-03-12 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.35 Å) | Cite: | Chemical rescue and inhibition studies to determine the role of arg301 in phosphite dehydrogenase. Plos One, 9, 2014
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6CDF
| Human CtBP1 (28-378) | Descriptor: | 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, C-terminal-binding protein 1, CALCIUM ION, ... | Authors: | Royer, W.E, Bellesis, A.G. | Deposit date: | 2018-02-08 | Release date: | 2018-05-09 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Assembly of human C-terminal binding protein (CtBP) into tetramers. J. Biol. Chem., 293, 2018
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6CDR
| Human CtBP1 (28-378) | Descriptor: | 1,2-ETHANEDIOL, 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, C-terminal-binding protein 1, ... | Authors: | Royer, W.E, Bellesis, A.G. | Deposit date: | 2018-02-09 | Release date: | 2018-05-09 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.399 Å) | Cite: | Assembly of human C-terminal binding protein (CtBP) into tetramers. J. Biol. Chem., 293, 2018
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4NFY
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3EVT
| Crystal structure of phosphoglycerate dehydrogenase from Lactobacillus plantarum | Descriptor: | Phosphoglycerate dehydrogenase | Authors: | Bonanno, J.B, Gilmore, M, Bain, K.T, Do, J, Sampathkumar, P, Wasserman, S, Sauder, J.M, Burley, S.K, Almo, S.C, New York SGX Research Center for Structural Genomics (NYSGXRC) | Deposit date: | 2008-10-13 | Release date: | 2008-10-21 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Crystal structure of phosphoglycerate dehydrogenase from Lactobacillus plantarum To be Published
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5DNA
| Crystal structure of Candida boidinii formate dehydrogenase | Descriptor: | FORMATE DEHYDROGENASE, SULFATE ION | Authors: | Guo, Q, Gakhar, L, Wichersham, K, Francis, K, Vardi-Kilshtain, A, Major, D.T, Cheatum, C.M, Kohen, A. | Deposit date: | 2015-09-09 | Release date: | 2016-05-04 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Structural and Kinetic Studies of Formate Dehydrogenase from Candida boidinii. Biochemistry, 55, 2016
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6BII
| Crystal Structure of Pyrococcus yayanosii Glyoxylate Hydroxypyruvate Reductase in complex with NADP and malonate (re-refinement of 5AOW) | Descriptor: | GLYCEROL, Glyoxylate reductase, MALONATE ION, ... | Authors: | Lassalle, L, Shabalin, I.G, Girard, E, Minor, W. | Deposit date: | 2017-11-02 | Release date: | 2018-01-17 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | New insights into the mechanism of substrates trafficking in Glyoxylate/Hydroxypyruvate reductases. Sci Rep, 6, 2016
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3JTM
| Structure of recombinant formate dehydrogenase from Arabidopsis thaliana | Descriptor: | AZIDE ION, Formate dehydrogenase, mitochondrial, ... | Authors: | Timofeev, V.I, Shabalin, I.G, Serov, A.E, Polyakov, K.M, Popov, V.O, Tishkov, V.I, Kuranova, I.P, Samigina, V.R. | Deposit date: | 2009-09-13 | Release date: | 2010-09-15 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (1.3 Å) | Cite: | Structure of recombinant formate dehydrogenase from Arabidopsis thaliana to be published
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4NJM
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5DT9
| Crystal structure of a putative D-Erythronate-4-Phosphate Dehydrogenase from Vibrio cholerae | Descriptor: | CHLORIDE ION, Erythronate-4-phosphate dehydrogenase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ... | Authors: | Stogios, P.J, Skarina, T, Savchenko, A, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID) | Deposit date: | 2015-09-17 | Release date: | 2015-09-30 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.663 Å) | Cite: | Crystal structure of a putative D-Erythronate-4-Phosphate Dehydrogenase from Vibrio cholerae To Be Published
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6CWA
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3K5P
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5DN9
| Crystal structure of Candida boidinii formate dehydrogenase complexed with NAD+ and azide | Descriptor: | AZIDE ION, CHLORIDE ION, FDH, ... | Authors: | Guo, Q, Gakhar, L, Wichersham, K, Francis, K, Vardi-Kilshtain, A, Major, D.T, Cheatum, C.M, Kohen, A. | Deposit date: | 2015-09-09 | Release date: | 2016-05-04 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Structural and Kinetic Studies of Formate Dehydrogenase from Candida boidinii. Biochemistry, 55, 2016
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6D4B
| Crystal structure of Candida boidinii formate dehydrogenase V123A mutant complexed with NAD+ and azide | Descriptor: | AZIDE ION, CHLORIDE ION, Formate dehydrogenase, ... | Authors: | Guo, Q, Ye, H, Gakhar, L, Cheatum, C.M, Kohen, A. | Deposit date: | 2018-04-17 | Release date: | 2019-04-24 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (1.45 Å) | Cite: | Oscillatory Active-site Motions Correlate with Kinetic Isotope Effects in Formate Dehydrogenase Acs Catalysis, 2019
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3KB6
| Crystal structure of D-Lactate dehydrogenase from aquifex aeolicus complexed with NAD and Lactic acid | Descriptor: | D-lactate dehydrogenase, DI(HYDROXYETHYL)ETHER, GLYCEROL, ... | Authors: | Antonyuk, S.V, Strange, R.W, Ellis, M.J, Bessho, Y, Kuramitsu, S, Yokoyama, S, Hasnain, S.S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2009-10-20 | Release date: | 2009-11-10 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.12 Å) | Cite: | Structure of D-lactate dehydrogenase from Aquifex aeolicus complexed with NAD(+) and lactic acid (or pyruvate). Acta Crystallogr.,Sect.F, 65, 2009
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3GA0
| CtBP1/BARS Gly172->Glu mutant structure: impairing NAD(H) binding and dimerization | Descriptor: | C-terminal-binding protein 1, FORMIC ACID | Authors: | Nardini, M, Valente, C, Ricagno, S, Luini, A, Corda, D, Bolognesi, M. | Deposit date: | 2009-02-16 | Release date: | 2009-04-21 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (3.4 Å) | Cite: | CtBP1/BARS Gly172-->Glu mutant structure: impairing NAD(H)-binding and dimerization Biochem.Biophys.Res.Commun., 381, 2009
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3GG9
| CRYSTAL STRUCTURE OF putative D-3-phosphoglycerate dehydrogenase oxidoreductase from Ralstonia solanacearum | Descriptor: | CHLORIDE ION, GLYCEROL, SULFATE ION, ... | Authors: | Patskovsky, Y, Ramagopal, U, Toro, R, Morano, C, Freeman, J, Chang, S, Sauder, J.M, Burley, S.K, Almo, S.C, New York SGX Research Center for Structural Genomics (NYSGXRC) | Deposit date: | 2009-02-27 | Release date: | 2009-03-24 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Crystal Structure of Putative D-3-Phosphoglycerate Dehydrogenase from Ralstonia Solanacearum To be Published
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