6PEX

An aldo keto reductase with 2-keto- L-gulonate reductase activity

Summary for 6PEX

Entry DOI	10.2210/pdb6pex/pdb
Descriptor	aldo keto reductase (2 entities in total)
Functional Keywords	d-isomer-specific 2-hydroxyacid dehydrogenase, l-tartaric acid pathway, 2-keto-l-gulonic acid, ascorbic acid degradation, oxidoreductase
Biological source	Vitis vinifera (Grape)
Total number of polymer chains	4
Total formula weight	144586.42
Authors	Yong, J.,Crystal, S.,Robert, D.H.,John, B.B. (deposition date: 2019-06-21, release date: 2019-09-11, Last modification date: 2023-10-11)
Primary citation	Jia, Y.,Burbidge, C.A.,Sweetman, C.,Schutz, E.,Soole, K.,Jenkins, C.,Hancock, R.D.,Bruning, J.B.,Ford, C.M. An aldo-keto reductase with 2-keto-l-gulonate reductase activity functions in l-tartaric acid biosynthesis from vitamin C inVitis vinifera. J.Biol.Chem., 294:15932-15946, 2019 Cited by PubMed: 31488549 DOI: 10.1074/jbc.RA119.010196 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.581 Å)

Structure validation