6PEX

An aldo keto reductase with 2-keto- L-gulonate reductase activity

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005829	cellular_component	cytosol
A	0008720	molecular_function	D-lactate dehydrogenase (NAD+) activity
A	0009853	biological_process	photorespiration
A	0016491	molecular_function	oxidoreductase activity
A	0016616	molecular_function	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
A	0016618	molecular_function	hydroxypyruvate reductase [NAD(P)H] activity
A	0030267	molecular_function	glyoxylate reductase (NADPH) activity
A	0047964	molecular_function	glyoxylate reductase (NADH) activity
A	0051287	molecular_function	NAD binding
A	0120509	molecular_function	hydroxypyruvate reductase (NADPH) activity
B	0005829	cellular_component	cytosol
B	0008720	molecular_function	D-lactate dehydrogenase (NAD+) activity
B	0009853	biological_process	photorespiration
B	0016491	molecular_function	oxidoreductase activity
B	0016616	molecular_function	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
B	0016618	molecular_function	hydroxypyruvate reductase [NAD(P)H] activity
B	0030267	molecular_function	glyoxylate reductase (NADPH) activity
B	0047964	molecular_function	glyoxylate reductase (NADH) activity
B	0051287	molecular_function	NAD binding
B	0120509	molecular_function	hydroxypyruvate reductase (NADPH) activity
C	0005829	cellular_component	cytosol
C	0008720	molecular_function	D-lactate dehydrogenase (NAD+) activity
C	0009853	biological_process	photorespiration
C	0016491	molecular_function	oxidoreductase activity
C	0016616	molecular_function	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
C	0016618	molecular_function	hydroxypyruvate reductase [NAD(P)H] activity
C	0030267	molecular_function	glyoxylate reductase (NADPH) activity
C	0047964	molecular_function	glyoxylate reductase (NADH) activity
C	0051287	molecular_function	NAD binding
C	0120509	molecular_function	hydroxypyruvate reductase (NADPH) activity
D	0005829	cellular_component	cytosol
D	0008720	molecular_function	D-lactate dehydrogenase (NAD+) activity
D	0009853	biological_process	photorespiration
D	0016491	molecular_function	oxidoreductase activity
D	0016616	molecular_function	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
D	0016618	molecular_function	hydroxypyruvate reductase [NAD(P)H] activity
D	0030267	molecular_function	glyoxylate reductase (NADPH) activity
D	0047964	molecular_function	glyoxylate reductase (NADH) activity
D	0051287	molecular_function	NAD binding
D	0120509	molecular_function	hydroxypyruvate reductase (NADPH) activity

Functional Information from PROSITE/UniProt

site_id	PS00065
Number of Residues	28
Details	D_2_HYDROXYACID_DH_1 D-isomer specific 2-hydroxyacid dehydrogenases NAD-binding signature. VGIIGlGRIGsaiakraegfscp.ISyHS

Chain	Residue	Details
A	VAL147-SER174

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	8
Details	Active site: {"evidences":[{"source":"PubMed","id":"31488549","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	4
Details	Active site: {"description":"Proton donor","evidences":[{"source":"PubMed","id":"31488549","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI3
Number of Residues	28
Details	Binding site: {"evidences":[{"source":"UniProtKB","id":"Q65CJ7","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

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