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4NTY
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BU of 4nty by Molmil
Cesium sites in the crystal structure of acid-sensing ion channel in complex with snake toxin
分子名称: 2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, Acid-sensing ion channel 1, Basic phospholipase A2 homolog Tx-beta, ...
著者Baconguis, I, Bohlen, C.J, Goehring, A, Julius, D, Gouaux, E.
登録日2013-12-02
公開日2014-02-19
最終更新日2019-12-25
実験手法X-RAY DIFFRACTION (2.65 Å)
主引用文献X-ray structure of Acid-sensing ion channel 1-snake toxin complex reveals open state of a na(+)-selective channel.
Cell(Cambridge,Mass.), 156, 2014
4ISO
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BU of 4iso by Molmil
Crystal Structure of Matriptase in complex with its inhibitor HAI-1
分子名称: DI(HYDROXYETHYL)ETHER, GLUTATHIONE, GLYCEROL, ...
著者Huang, M.D, Zhao, B.Y, Yuan, C, Li, R.
登録日2013-01-16
公開日2013-03-06
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.01 Å)
主引用文献Crystal structures of matriptase in complex with its inhibitor hepatocyte growth factor activator inhibitor-1.
J.Biol.Chem., 288, 2013
4ISN
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BU of 4isn by Molmil
Crystal Structure of Matriptase in complex with its inhibitor HAI-1
分子名称: GLUTATHIONE, Kunitz-type protease inhibitor 1, Suppressor of tumorigenicity 14 protein, ...
著者Huang, M.D, Zhao, B.Y, Yuan, C, Li, R.
登録日2013-01-16
公開日2013-03-06
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.45 Å)
主引用文献Crystal structures of matriptase in complex with its inhibitor hepatocyte growth factor activator inhibitor-1.
J.Biol.Chem., 288, 2013
4ISL
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BU of 4isl by Molmil
Crystal Structure of the inactive Matriptase in complex with its inhibitor HAI-1
分子名称: GLUTATHIONE, GLYCEROL, Kunitz-type protease inhibitor 1, ...
著者Huang, M.D, Zhao, B.Y, Yuan, C, Li, R.
登録日2013-01-16
公開日2013-03-06
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.29 Å)
主引用文献Crystal structures of matriptase in complex with its inhibitor hepatocyte growth factor activator inhibitor-1.
J.Biol.Chem., 288, 2013
2RA3
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BU of 2ra3 by Molmil
Human cationic trypsin complexed with bovine pancreatic trypsin inhibitor (BPTI)
分子名称: CALCIUM ION, Pancreatic trypsin inhibitor, SULFATE ION, ...
著者Salameh, M.A, Soares, A.S, Radisky, E.S.
登録日2007-09-14
公開日2007-12-11
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.46 Å)
主引用文献Structural Basis for Accelerated Cleavage of Bovine Pancreatic Trypsin Inhibitor (BPTI) by Human Mesotrypsin.
J.Biol.Chem., 283, 2008
2R9P
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BU of 2r9p by Molmil
Human mesotrypsin complexed with bovine pancreatic trypsin inhibitor(BPTI)
分子名称: Pancreatic trypsin inhibitor, SULFATE ION, Trypsin-3
著者Salameh, M.A, Soares, A.S, Radisky, E.S.
登録日2007-09-13
公開日2007-12-11
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Structural Basis for Accelerated Cleavage of Bovine Pancreatic Trypsin Inhibitor (BPTI) by Human Mesotrypsin.
J.Biol.Chem., 283, 2008
2TGP
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BU of 2tgp by Molmil
THE GEOMETRY OF THE REACTIVE SITE AND OF THE PEPTIDE GROUPS IN TRYPSIN, TRYPSINOGEN AND ITS COMPLEXES WITH INHIBITORS
分子名称: CALCIUM ION, SULFATE ION, TRYPSIN INHIBITOR, ...
著者Huber, R, Bode, W, Deisenhofer, J, Schwager, P.
登録日1982-09-27
公開日1983-01-18
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献The Geometry of the Reactive Site and of the Peptide Groups in Trypsin, Trypsinogen and its Complexes with Inhibitors
Acta Crystallogr.,Sect.B, 39, 1983
2TPI
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BU of 2tpi by Molmil
ON THE DISORDERED ACTIVATION DOMAIN IN TRYPSINOGEN. CHEMICAL LABELLING AND LOW-TEMPERATURE CRYSTALLOGRAPHY
分子名称: ISOLEUCINE, MERCURY (II) ION, TRYPSIN INHIBITOR, ...
著者Walter, J, Steigemann, W, Singh, T.P, Bartunik, H, Bode, W, Huber, R.
登録日1981-10-26
公開日1982-03-04
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献On the Disordered Activation Domain in Trypsinogen. Chemical Labelling and Low-Temperature Crystallography
Acta Crystallogr.,Sect.B, 38, 1982
3FP6
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BU of 3fp6 by Molmil
Anionic trypsin in complex with bovine pancreatic trypsin inhibitor (BPTI) determined to the 1.49 A resolution limit
分子名称: 1,2-ETHANEDIOL, Anionic trypsin-2, CALCIUM ION, ...
著者Zakharova, E, Horvath, M.P, Goldenberg, D.P.
登録日2009-01-04
公開日2009-02-17
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.49 Å)
主引用文献Structure of a serine protease poised to resynthesize a peptide bond.
Proc.Natl.Acad.Sci.USA, 106, 2009
5NX1
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BU of 5nx1 by Molmil
Combinatorial Engineering of Proteolytically Resistant APPI Variants that Selectively Inhibit Human Kallikrein 6 for Cancer Therapy
分子名称: Amyloid-beta A4 protein, Kallikrein-6
著者Shahar, A, Sananes, A, Radisky, E.S, Papo, N.
登録日2017-05-09
公開日2018-05-30
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.853 Å)
主引用文献A potent, proteolysis-resistant inhibitor of kallikrein-related peptidase 6 (KLK6) for cancer therapy, developed by combinatorial engineering.
J.Biol.Chem., 293, 2018
3FP8
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BU of 3fp8 by Molmil
Anionic trypsin variant S195A in complex with bovine pancreatic trypsin inhibitor (BPTI) determined to the 1.46 A resolution limit
分子名称: 1,2-ETHANEDIOL, Anionic trypsin-2, CALCIUM ION, ...
著者Zakharova, E, Horvath, M.P, Goldenberg, D.P, Curtice, K.
登録日2009-01-04
公開日2009-02-17
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.46 Å)
主引用文献Structure of a serine protease poised to resynthesize a peptide bond.
Proc.Natl.Acad.Sci.USA, 106, 2009
5NX3
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BU of 5nx3 by Molmil
Combinatorial Engineering of Proteolytically Resistant APPI Variants that Selectively Inhibit Human Kallikrein 6 for Cancer Therapy
分子名称: Amyloid-beta A4 protein, Kallikrein-6
著者Shahar, A, Sananes, A, Radisky, E.S, Papo, N.
登録日2017-05-09
公開日2018-05-30
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.296 Å)
主引用文献A potent, proteolysis-resistant inhibitor of kallikrein-related peptidase 6 (KLK6) for cancer therapy, developed by combinatorial engineering.
J.Biol.Chem., 293, 2018
3D65
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BU of 3d65 by Molmil
Crystal structure of Textilinin-1, a Kunitz-type serine protease inhibitor from the Australian Common Brown snake venom, in complex with trypsin
分子名称: CALCIUM ION, Cationic trypsin, Textilinin
著者Millers, E.-K.I, Masci, P.P, Lavin, M.F, de Jersey, J, Guddat, L.W.
登録日2008-05-19
公開日2009-06-16
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.64 Å)
主引用文献Crystal structure of Textilinin-1, a Kunitz-type serine protease inhibitor from the Australian Common Brown snake venom, in complex with trypsin
To be Published
3FP7
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BU of 3fp7 by Molmil
Anionic trypsin variant S195A in complex with bovine pancreatic trypsin inhibitor (BPTI) cleaved at the scissile bond (LYS15-ALA16) determined to the 1.46 A resolution limit
分子名称: 1,2-ETHANEDIOL, Anionic trypsin-2, CALCIUM ION, ...
著者Zakharova, E, Horvath, M.P, Goldenberg, D.P.
登録日2009-01-04
公開日2009-02-17
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.46 Å)
主引用文献Structure of a serine protease poised to resynthesize a peptide bond.
Proc.Natl.Acad.Sci.USA, 106, 2009
2FI4
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BU of 2fi4 by Molmil
Crystal structure of a BPTI variant (Cys14->Ser) in complex with trypsin
分子名称: 1,2-ETHANEDIOL, CALCIUM ION, Cationic trypsin, ...
著者Zakharova, E, Horvath, M.P, Goldenberg, D.P.
登録日2005-12-27
公開日2006-01-24
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.58 Å)
主引用文献Functional and structural roles of the Cys14-Cys38 disulfide of bovine pancreatic trypsin inhibitor.
J.Mol.Biol., 382, 2008
3BTF
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BU of 3btf by Molmil
THE CRYSTAL STRUCTURES OF THE COMPLEXES BETWEEN BOVINE BETA-TRYPSIN AND TEN P1 VARIANTS OF BPTI.
分子名称: CALCIUM ION, PROTEIN (PANCREATIC TRYPSIN INHIBITOR), PROTEIN (TRYPSIN), ...
著者Helland, R, Otlewski, J, Sundheim, O, Dadlez, M, Smalas, A.O.
登録日1999-03-10
公開日2000-03-13
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献The crystal structures of the complexes between bovine beta-trypsin and ten P1 variants of BPTI.
J.Mol.Biol., 287, 1999
3BTM
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BU of 3btm by Molmil
THE CRYSTAL STRUCTURES OF THE COMPLEXES BETWEEN BOVINE BETA-TRYPSIN AND TEN P1 VARIANTS OF BPTI
分子名称: CALCIUM ION, PROTEIN (PANCREATIC TRYPSIN INHIBITOR), PROTEIN (TRYPSIN), ...
著者Helland, R, Otlewski, J, Sundheim, O, Dadlez, M, Smalas, A.O.
登録日1999-03-10
公開日2000-03-13
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献The crystal structures of the complexes between bovine beta-trypsin and ten P1 variants of BPTI.
J.Mol.Biol., 287, 1999
3U1J
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BU of 3u1j by Molmil
Aprotinin bound to Dengue virus protease
分子名称: Pancreatic trypsin inhibitor, Serine protease NS3, Serine protease subunit NS2B
著者Noble, C.G.
登録日2011-09-30
公開日2011-11-09
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Ligand-bound structures of the dengue virus protease reveal the active conformation
J.Virol., 86, 2012
3TPI
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BU of 3tpi by Molmil
THE GEOMETRY OF THE REACTIVE SITE AND OF THE PEPTIDE GROUPS IN TRYPSIN, TRYPSINOGEN AND ITS COMPLEXES WITH INHIBITORS
分子名称: BOVINE PANCREATIC TRYPSIN INHIBITOR, CALCIUM ION, ISOLEUCINE, ...
著者Huber, R, Bode, W, Deisenhofer, J, Schwager, P.
登録日1982-09-27
公開日1983-01-18
最終更新日2012-02-01
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献The Geometry of the Reactive Site and of the Peptide Groups in Trypsin, Trypsinogen and its Complexes with Inhibitors
Acta Crystallogr.,Sect.B, 39, 1983
3BTE
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BU of 3bte by Molmil
The Crystal Structures of the Complexes Between Bovine Beta-Trypsin and Ten P1 Variants of BPTI.
分子名称: CALCIUM ION, PANCREATIC TRYPSIN INHIBITOR, SULFATE ION, ...
著者Helland, R, Otlewski, J, Sundheim, O, Dadlez, M, Smalas, A.O.
登録日1999-03-11
公開日2000-03-15
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献The crystal structures of the complexes between bovine beta-trypsin and ten P1 variants of BPTI.
J.Mol.Biol., 287, 1999
3BTG
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BU of 3btg by Molmil
THE CRYSTAL STRUCTURES OF THE COMPLEXES BETWEEN BOVINE BETA-TRYPSIN AND TEN P1 VARIANTS OF BPTI
分子名称: CALCIUM ION, PROTEIN (PANCREATIC TRYPSIN INHIBITOR), PROTEIN (TRYPSIN), ...
著者Helland, R, Otlewski, J, Sundheim, O, Dadlez, M, Smalas, A.O.
登録日1999-03-10
公開日2000-03-13
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献The crystal structures of the complexes between bovine beta-trypsin and ten P1 variants of BPTI.
J.Mol.Biol., 287, 1999
4BNR
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BU of 4bnr by Molmil
Extremely stable complex of crayfish trypsin with bovine trypsin inhibitor
分子名称: CALCIUM ION, HEPATOPANCREAS TRYPSIN, PANCREATIC TRYPSIN INHIBITOR, ...
著者Molnar, T, Voros, J, Szeder, B, Takats, K, Kardos, J, Katona, G, Graf, L.
登録日2013-05-17
公開日2013-09-04
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Comparison of Complexes Formed by a Crustacean and a Vertebrate Trypsin with Bovine Pancreatic Trypsin Inhibitor - the Key to Achieving Extreme Stability?
FEBS J., 280, 2013
2ODY
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BU of 2ody by Molmil
Thrombin-bound boophilin displays a functional and accessible reactive-site loop
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Boophilin, PHOSPHATE ION, ...
著者Macedo-Ribeiro, S, Fuentes-Prior, P, Pereira, P.J.B.
登録日2006-12-27
公開日2008-01-22
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献Isolation, cloning and structural characterisation of boophilin, a multifunctional kunitz-type proteinase inhibitor from the cattle tick.
Plos One, 3, 2008
4DG4
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BU of 4dg4 by Molmil
Human mesotrypsin-S39Y complexed with bovine pancreatic trypsin inhibitor (BPTI)
分子名称: CALCIUM ION, PRSS3 protein, Pancreatic trypsin inhibitor, ...
著者Salameh, M.A, Soares, A.S, Radisky, E.S.
登録日2012-01-24
公開日2012-09-12
最終更新日2018-01-24
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Presence versus absence of hydrogen bond donor Tyr-39 influences interactions of cationic trypsin and mesotrypsin with protein protease inhibitors.
Protein Sci., 21, 2012
4BD9
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BU of 4bd9 by Molmil
Structure of the complex between SmCI and human carboxypeptidase A4
分子名称: CARBOXYPEPTIDASE A4, CARBOXYPEPTIDASE INHIBITOR SMCI, ZINC ION
著者Alonso-del-Ribero, M, Reytor, M.L, Trejo, S.A, Chavez, M.A, Aviles, F.X, Reverter, D.
登録日2012-10-05
公開日2013-07-17
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献A Noncanonical Mechanism of Carboxypeptidase Inhibition Revealed by the Crystal Structure of the Tri-Kunitz Smci in Complex with Human Cpa4.
Structure, 21, 2013

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