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8SN2	Cryo-EM structure of the human nucleosome core particle in complex with RNF168 and UbcH5c (UbcH5c chemically conjugated to histone H2A) Descriptor: DNA (147-MER), E3 ubiquitin-protein ligase RNF168, Histone H2A type 1-B/E, ... Authors: Hu, Q, Botuyan, M.V, Zhao, D, Cui, G, Mer, G. Deposit date: 2023-04-26 Release date: 2024-01-17 Last modified: 2024-03-20 Method: ELECTRON MICROSCOPY (3.6 Å) Cite: Mechanisms of RNF168 nucleosome recognition and ubiquitylation. Mol.Cell, 84, 2024
8SN5	Cryo-EM structure of the human nucleosome core particle in complex with RNF168 and UbcH5c~Ub (UbcH5c chemically conjugated to histone H2A) (class 3) Descriptor: DNA (147-MER), E3 ubiquitin-protein ligase RNF168, Histone H2A type 1-B/E, ... Authors: Hu, Q, Botuyan, M.V, Zhao, D, Cui, G, Mer, G. Deposit date: 2023-04-26 Release date: 2024-01-17 Last modified: 2024-10-09 Method: ELECTRON MICROSCOPY (3.9 Å) Cite: Mechanisms of RNF168 nucleosome recognition and ubiquitylation. Mol.Cell, 84, 2024
8SNA	Cryo-EM structure of the human nucleosome core particle in complex with RNF168 and UbcH5c with backside ubiquitin (UbcH5c chemically conjugated to histone H2A) (class 2) Descriptor: DNA (147-MER), E3 ubiquitin-protein ligase RNF168, Histone H2A type 1-B/E, ... Authors: Hu, Q, Botuyan, M.V, Zhao, D, Cui, G, Mer, G. Deposit date: 2023-04-26 Release date: 2024-01-17 Last modified: 2024-03-20 Method: ELECTRON MICROSCOPY (4 Å) Cite: Mechanisms of RNF168 nucleosome recognition and ubiquitylation. Mol.Cell, 84, 2024
8SN3	Cryo-EM structure of the human nucleosome core particle in complex with RNF168 and UbcH5c~Ub (UbcH5c chemically conjugated to histone H2A) (class 1) Descriptor: DNA (147-MER), E3 ubiquitin-protein ligase RNF168, Histone H2A type 1-B/E, ... Authors: Hu, Q, Botuyan, M.V, Zhao, D, Cui, G, Mer, G. Deposit date: 2023-04-26 Release date: 2024-01-17 Last modified: 2024-03-20 Method: ELECTRON MICROSCOPY (3.8 Å) Cite: Mechanisms of RNF168 nucleosome recognition and ubiquitylation. Mol.Cell, 84, 2024
8SN8	Cryo-EM structure of the human nucleosome core particle in complex with RNF168 and UbcH5c~Ub (UbcH5c chemically conjugated to histone H2A) (class 6) Descriptor: DNA (147-MER), E3 ubiquitin-protein ligase RNF168, Histone H2A type 1-B/E, ... Authors: Hu, Q, Botuyan, M.V, Zhao, D, Cui, G, Mer, G. Deposit date: 2023-04-26 Release date: 2024-01-17 Last modified: 2024-03-20 Method: ELECTRON MICROSCOPY (3.7 Å) Cite: Mechanisms of RNF168 nucleosome recognition and ubiquitylation. Mol.Cell, 84, 2024
8SN9	Cryo-EM structure of the human nucleosome core particle in complex with RNF168 and UbcH5c with backside ubiquitin (UbcH5c chemically conjugated to histone H2A) (class 1) Descriptor: DNA (147-MER), E3 ubiquitin-protein ligase RNF168, Histone H2A type 1-B/E, ... Authors: Hu, Q, Botuyan, M.V, Zhao, D, Cui, G, Mer, G. Deposit date: 2023-04-26 Release date: 2024-01-17 Last modified: 2024-03-20 Method: ELECTRON MICROSCOPY (3.9 Å) Cite: Mechanisms of RNF168 nucleosome recognition and ubiquitylation. Mol.Cell, 84, 2024
5AVC	human nucleosome core particle Descriptor: DNA (147-MER), Histone H2A type 1-B/E, Histone H2B type 1-J, ... Authors: Wakamori, M, Fujii, Y, Umehara, T, Yokoyama, S. Deposit date: 2015-06-12 Release date: 2015-12-23 Last modified: 2024-03-20 Method: X-RAY DIFFRACTION (2.4 Å) Cite: Intra- and inter-nucleosomal interactions of the histone H4 tail revealed with a human nucleosome core particle with genetically-incorporated H4 tetra-acetylation Sci Rep, 5, 2015
8SN0	Cryo-EM structure of the human nucleosome core particle in complex with RNF168 and UbcH5c~Ub (UbcH5c chemically conjugated to histone H2A. No density for Ub.) (class 5) Descriptor: DNA (147-MER), E3 ubiquitin-protein ligase RNF168, Histone H2A type 1-B/E, ... Authors: Hu, Q, Botuyan, M.V, Zhao, D, Cui, G, Mer, G. Deposit date: 2023-04-26 Release date: 2024-01-17 Last modified: 2024-03-20 Method: ELECTRON MICROSCOPY (3.2 Å) Cite: Mechanisms of RNF168 nucleosome recognition and ubiquitylation. Mol.Cell, 84, 2024
8SN1	Cryo-EM structure of the human nucleosome core particle in complex with RNF168 and UbcH5c~Ub (UbcH5c chemically conjugated to histone H2A. No density for Ub.) (class 6) Descriptor: DNA (147-MER), E3 ubiquitin-protein ligase RNF168, Histone H2A type 1-B/E, ... Authors: Hu, Q, Botuyan, M.V, Zhao, D, Cui, G, Mer, G. Deposit date: 2023-04-26 Release date: 2024-01-17 Last modified: 2024-03-20 Method: ELECTRON MICROSCOPY (3.3 Å) Cite: Mechanisms of RNF168 nucleosome recognition and ubiquitylation. Mol.Cell, 84, 2024
5AVB	human nucleosome core particle Descriptor: DNA (147-MER), Histone H2A type 1-B/E, Histone H2B type 1-J, ... Authors: Wakamori, M, Fujii, Y, Umehara, T, Yokoyama, S. Deposit date: 2015-06-12 Release date: 2015-12-23 Last modified: 2024-03-20 Method: X-RAY DIFFRACTION (2.4 Å) Cite: Intra- and inter-nucleosomal interactions of the histone H4 tail revealed with a human nucleosome core particle with genetically-incorporated H4 tetra-acetylation Sci Rep, 5, 2015
5B32	The crystal structure of the heterotypic H2AZ/H2A nucleosome with H3.3. Descriptor: CHLORIDE ION, DNA (146-MER), Histone H2A type 1-B/E, ... Authors: Horikoshi, N, Taguchi, H, Arimura, Y, Kurumizaka, H. Deposit date: 2016-02-08 Release date: 2016-08-03 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (2.35 Å) Cite: Crystal structures of heterotypic nucleosomes containing histones H2A.Z and H2A. Open Biology, 6, 2016
5B33	The crystal structure of the H2AZ nucleosome with H3.3. Descriptor: DNA (146-MER), Histone H2A.Z, Histone H2B type 1-J, ... Authors: Horikoshi, N, Taguchi, H, Arimura, Y, Kurumizaka, H. Deposit date: 2016-02-08 Release date: 2016-08-03 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (2.925 Å) Cite: Crystal structures of heterotypic nucleosomes containing histones H2A.Z and H2A. Open Biology, 6, 2016
5B2I	Human nucleosome containing CpG unmethylated DNA Descriptor: DNA (146-MER), Histone H2A type 1-B/E, Histone H2B type 1-J, ... Authors: Fujii, Y, Wakamori, M, Umehara, T, Yokoyama, S. Deposit date: 2016-01-16 Release date: 2016-06-15 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (3 Å) Cite: Crystal structure of human nucleosome core particle containing enzymatically introduced CpG methylation. Febs Open Bio, 6, 2016
5BNV	Crystal structure of Human MCM2 HBD chaperoning a histone H3-H4 tetramer Descriptor: DNA replication licensing factor MCM2, Histone H3.3, Histone H4, ... Authors: Huang, H, Patel, D.J. Deposit date: 2015-05-26 Release date: 2015-06-17 Last modified: 2024-03-06 Method: X-RAY DIFFRACTION (2.795 Å) Cite: A unique binding mode enables MCM2 to chaperone histones H3-H4 at replication forks. Nat.Struct.Mol.Biol., 22, 2015
8T9G	Automethylated PRC2 dimer bound to nucleosome Descriptor: DNA (226-MER), Histone H2A type 1, Histone H2B 1.1, ... Authors: Sauer, P.V, Pavlenko, E, Nogales, E, Poepsel, S. Deposit date: 2023-06-23 Release date: 2024-09-25 Last modified: 2024-10-09 Method: ELECTRON MICROSCOPY (6.2 Å) Cite: Activation of automethylated PRC2 by dimerization on chromatin. Mol.Cell, 2024
8U17	The ternary complex structure of DDB1-CRBN-SALL4(ZF1,2)-long bound to Pomalidomide Descriptor: DNA damage-binding protein 1, Protein cereblon, S-Pomalidomide, ... Authors: Clifton, M.C, Ma, X, Ornelas, E. Deposit date: 2023-08-30 Release date: 2023-12-27 Method: X-RAY DIFFRACTION (3.1 Å) Cite: Structural and biophysical comparisons of the pomalidomide- and CC-220-induced interactions of SALL4 with cereblon. Sci Rep, 13, 2023
8U14	Cryo-EM structure of the human nucleosome core particle ubiquitylated at histone H2A lysine 15 in complex with RNF168-UbcH5c (class 2) Descriptor: DNA (146-MER), DNA (147-MER), E3 ubiquitin-protein ligase RNF168, ... Authors: Hu, Q, Botuyan, M.V, Zhao, D, Cui, G, Mer, G. Deposit date: 2023-08-30 Release date: 2024-01-17 Last modified: 2024-10-16 Method: ELECTRON MICROSCOPY (3.9 Å) Cite: Mechanisms of RNF168 nucleosome recognition and ubiquitylation. Mol.Cell, 84, 2024
8TGP	Crystal structure of SIRT2 with FAM-PEG4-H4K16(myristoyl) peptide Descriptor: H4K16(myristoyl) peptide, MYRISTIC ACID, NAD-dependent protein deacetylase sirtuin-2, ... Authors: Nicely, N.I, Weiser, B.P. Deposit date: 2023-07-12 Release date: 2024-01-24 Method: X-RAY DIFFRACTION (1.76 Å) Cite: Effects of Dimerization on the Deacylase Activities of Human SIRT2. Biochemistry, 62, 2023
8TXX	Cryo-EM structure of the human nucleosome core particle ubiquitylated at histone H2A K15 in complex with RNF168 (Class 3) Descriptor: DNA (147-MER), E3 ubiquitin-protein ligase RNF168, Histone H2A type 1-B/E, ... Authors: Hu, Q, Botuyan, M.V, Zhao, D, Cui, G, Mer, G. Deposit date: 2023-08-24 Release date: 2024-01-17 Last modified: 2024-03-20 Method: ELECTRON MICROSCOPY (3.7 Å) Cite: Mechanisms of RNF168 nucleosome recognition and ubiquitylation. Mol.Cell, 84, 2024
8TXV	Cryo-EM structure of the human nucleosome core particle ubiquitylated at histone H2A K15 in complex with RNF168 (Class 1) Descriptor: DNA (147-MER), E3 ubiquitin-protein ligase RNF168, Histone H2A type 1-B/E, ... Authors: Hu, Q, Botuyan, M.V, Zhao, D, Cui, G, Mer, G. Deposit date: 2023-08-24 Release date: 2024-01-17 Last modified: 2024-03-20 Method: ELECTRON MICROSCOPY (3.8 Å) Cite: Mechanisms of RNF168 nucleosome recognition and ubiquitylation. Mol.Cell, 84, 2024
8U13	Cryo-EM structure of the human nucleosome core particle ubiquitylated at histone H2A lysine 15 in complex with RNF168-UbcH5c (class 1) Descriptor: DNA (146-MER), DNA (147-MER), E3 ubiquitin-protein ligase RNF168, ... Authors: Hu, Q, Botuyan, M.V, Zhao, D, Cui, G, Mer, G. Deposit date: 2023-08-30 Release date: 2024-01-17 Last modified: 2024-03-20 Method: ELECTRON MICROSCOPY (3.8 Å) Cite: Mechanisms of RNF168 nucleosome recognition and ubiquitylation. Mol.Cell, 84, 2024
8TXW	Cryo-EM structure of the human nucleosome core particle ubiquitylated at histone H2A K15 in complex with RNF168 (Class 2) Descriptor: DNA (147-MER), E3 ubiquitin-protein ligase RNF168, Histone H2A type 1-B/E, ... Authors: Hu, Q, Botuyan, M.V, Zhao, D, Cui, G, Mer, G. Deposit date: 2023-08-24 Release date: 2024-01-17 Last modified: 2024-10-09 Method: ELECTRON MICROSCOPY (3.6 Å) Cite: Mechanisms of RNF168 nucleosome recognition and ubiquitylation. Mol.Cell, 84, 2024
5O9Z	Cryo-EM structure of a pre-catalytic human spliceosome primed for activation (B complex) Descriptor: 116 kDa U5 small nuclear ribonucleoprotein component, Homo sapiens RNA, U6 small nuclear 1 (RNU6-1), ... Authors: Bertram, K, Kastner, B. Deposit date: 2017-06-20 Release date: 2017-08-16 Last modified: 2018-10-24 Method: ELECTRON MICROSCOPY (4.5 Å) Cite: Cryo-EM Structure of a Pre-catalytic Human Spliceosome Primed for Activation. Cell, 170, 2017
5CPI	Nucleosome containing unmethylated Sat2R DNA Descriptor: DNA (146-MER), Histone H2A type 1-B/E, Histone H2B type 1-J, ... Authors: Osakabe, A, Arimura, Y, Adachi, F, Maehara, K, Ohkawa, Y, Kurumizaka, H. Deposit date: 2015-07-21 Release date: 2015-10-28 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (2.902 Å) Cite: Influence of DNA methylation on positioning and DNA flexibility of nucleosomes with pericentric satellite DNA. Open Biology, 5, 2015
5CPK	Nucleosome containing methylated Sat2L DNA Descriptor: DNA (145-MER), Histone H2A type 1-B/E, Histone H2B type 1-J, ... Authors: Osakabe, A, Arimura, Y, Adachi, F, Maehara, K, Ohkawa, Y, Kurumizaka, H. Deposit date: 2015-07-21 Release date: 2015-10-28 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (2.632 Å) Cite: Influence of DNA methylation on positioning and DNA flexibility of nucleosomes with pericentric satellite DNA. Open Biology, 5, 2015

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