2D9Q
 
 | | Crystal Structure of the Human GCSF-Receptor Signaling Complex | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CSF3, Granulocyte colony-stimulating factor receptor | | Authors: | Tamada, T, Kuroki, R. | | Deposit date: | 2005-12-12 | | Release date: | 2006-02-07 | | Last modified: | 2023-10-25 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Homodimeric cross-over structure of the human granulocyte colony-stimulating factor (GCSF) receptor signaling complex
Proc.Natl.Acad.Sci.Usa, 103, 2006
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2DA3
 | | Solution structure of the third homeobox domain of AT-binding transcription factor 1 (ATBF1) | | Descriptor: | Alpha-fetoprotein enhancer binding protein | | Authors: | Ohnishi, S, Kigawa, T, Tomizawa, T, Koshiba, S, Inoue, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | Deposit date: | 2005-12-13 | | Release date: | 2006-06-13 | | Last modified: | 2024-05-29 | | Method: | SOLUTION NMR | | Cite: | Solution structure of the third homeobox domain of AT-binding transcription factor 1 (ATBF1)
To be Published
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2DMS
 | | Solution structure of the homeobox domain of Homeobox protein OTX2 | | Descriptor: | Homeobox protein OTX2 | | Authors: | Ohnishi, S, Saito, K, Koshiba, S, Inoue, M, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | Deposit date: | 2006-04-24 | | Release date: | 2006-10-24 | | Last modified: | 2024-05-29 | | Method: | SOLUTION NMR | | Cite: | Solution structure of the homeobox domain of Homeobox protein OTX2
To be Published
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2DS1
 | | Human cyclin dependent kinase 2 complexed with the CDK4 inhibitor | | Descriptor: | (13R,15S)-13-METHYL-16-OXA-8,9,12,22,24-PENTAAZAHEXACYCLO[15.6.2.16,9.1,12,15.0,2,7.0,21,25]HEPTACOSA-1(24),2,4,6,17(25 ),18,20-HEPTAENE-23,26-DIONE, Cell division protein kinase 2 | | Authors: | Ikuta, M. | | Deposit date: | 2006-06-17 | | Release date: | 2007-06-19 | | Last modified: | 2023-10-25 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Structure-based drug design of a highly potent CDK1,2,4,6 inhibitor with novel macrocyclic quinoxalin-2-one structure
Bioorg.Med.Chem.Lett., 16, 2006
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1VK5
 | | X-ray Structure of Gene Product from Arabidopsis Thaliana At3g22680 | | Descriptor: | 1,2-ETHANEDIOL, 3-[(3-CHOLAMIDOPROPYL)DIMETHYLAMMONIO]-1-PROPANESULFONATE, SULFATE ION, ... | | Authors: | Wesenberg, G.E, Smith, D.W, Phillips Jr, G.N, Johnson, K.A, Bingman, C.A, Allard, S.T.M, Center for Eukaryotic Structural Genomics (CESG) | | Deposit date: | 2004-05-06 | | Release date: | 2004-05-18 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (1.604 Å) | | Cite: | Structure at 1.6 A resolution of the protein from gene locus At3g22680 from Arabidopsis thaliana.
Acta Crystallogr.,Sect.F, 61, 2005
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2F21
 | | human Pin1 Fip mutant | | Descriptor: | PENTAETHYLENE GLYCOL, Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 | | Authors: | Jager, M, Zhang, Y, Bowman, M.E, Noel, J.P, Kelly, J.W. | | Deposit date: | 2005-11-15 | | Release date: | 2006-06-20 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (1.5 Å) | | Cite: | Structure-function-folding relationship in a WW domain.
Proc.Natl.Acad.Sci.Usa, 103, 2006
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2F6J
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2E32
 | | Structural basis for selection of glycosylated substrate by SCFFbs1 ubiquitin ligase | | Descriptor: | F-box only protein 2, S-phase kinase-associated protein 1A | | Authors: | Mizushima, T, Yoshida, Y, Kumanomidou, T, Hasegawa, Y, Yamane, T, Tanaka, K. | | Deposit date: | 2006-11-20 | | Release date: | 2007-03-20 | | Last modified: | 2023-10-25 | | Method: | X-RAY DIFFRACTION (3.52 Å) | | Cite: | Structural basis for the selection of glycosylated substrates by SCFFbs1 ubiquitin ligase
Proc.Natl.Acad.Sci.Usa, 104, 2007
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2E5C
 | | Crystal structure of Human NMPRTase complexed with 5'-phosphoribosyl-1'-pyrophosphate | | Descriptor: | 1-O-pyrophosphono-5-O-phosphono-alpha-D-ribofuranose, Nicotinamide phosphoribosyltransferase | | Authors: | Takahashi, R, Nakamura, S, Kobayashi, Y, Ohkubo, T. | | Deposit date: | 2006-12-20 | | Release date: | 2007-12-25 | | Last modified: | 2023-10-25 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Structure and reaction mechanism of human nicotinamide phosphoribosyltransferase
J.Biochem., 147, 2010
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2E6Z
 | | Solution structure of the second KOW motif of human transcription elongation factor SPT5 | | Descriptor: | Transcription elongation factor SPT5 | | Authors: | Tanabe, W, Suzuki, S, Muto, Y, Inoue, M, Kigawa, T, Terada, T, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | Deposit date: | 2007-01-05 | | Release date: | 2007-07-10 | | Last modified: | 2024-05-29 | | Method: | SOLUTION NMR | | Cite: | Solution structure of the second KOW motif of human transcription elongation factor SPT5
To be Published
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2FUH
 | | Solution Structure of the UbcH5c/Ub Non-covalent Complex | | Descriptor: | Ubiquitin, Ubiquitin-conjugating enzyme E2 D3 | | Authors: | Brzovic, P.S, Lissounov, A, Hoyt, D.W, Klevit, R.E. | | Deposit date: | 2006-01-26 | | Release date: | 2006-03-28 | | Last modified: | 2024-05-29 | | Method: | SOLUTION NMR | | Cite: | A UbcH5/Ubiquitin Noncovalent Complex Is Required for Processive BRCA1-Directed Ubiquitination.
Mol.Cell, 21, 2006
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2FUI
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7Y1J
 | | Structure of SUR2A in complex with Mg-ATP and repaglinide in the inward-facing conformation. | | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, ATP-binding cassette sub-family C member 9, MAGNESIUM ION, ... | | Authors: | Chen, L, Ding, D, Hou, T. | | Deposit date: | 2022-06-08 | | Release date: | 2023-06-14 | | Last modified: | 2023-10-11 | | Method: | ELECTRON MICROSCOPY (3 Å) | | Cite: | The inhibition mechanism of the SUR2A-containing K ATP channel by a regulatory helix.
Nat Commun, 14, 2023
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7Y1L
 | | Structure of SUR2B in complex with Mg-ATP and repaglinide in the inward-facing conformation | | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Isoform SUR2B of ATP-binding cassette sub-family C member 9, MAGNESIUM ION, ... | | Authors: | Chen, L, Ding, D, Hou, T. | | Deposit date: | 2022-06-08 | | Release date: | 2023-06-14 | | Last modified: | 2023-10-11 | | Method: | ELECTRON MICROSCOPY (3.73 Å) | | Cite: | The inhibition mechanism of the SUR2A-containing K ATP channel by a regulatory helix.
Nat Commun, 14, 2023
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7Y1K
 | | Structure of SUR2A in complex with Mg-ATP, Mg-ADP and repaglinide in the inward-facing conformation | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP-binding cassette sub-family C member 9, ... | | Authors: | Chen, L, Ding, D, Hou, T. | | Deposit date: | 2022-06-08 | | Release date: | 2023-06-14 | | Last modified: | 2023-10-11 | | Method: | ELECTRON MICROSCOPY (3.8 Å) | | Cite: | The inhibition mechanism of the SUR2A-containing K ATP channel by a regulatory helix.
Nat Commun, 14, 2023
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7Y1M
 | | Structure of SUR2B in complex with Mg-ATP, Mg-ADP, and repaglinide in the inward-facing conformation | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Isoform SUR2B of ATP-binding cassette sub-family C member 9, ... | | Authors: | Chen, L, Ding, D, Hou, T. | | Deposit date: | 2022-06-08 | | Release date: | 2023-06-14 | | Last modified: | 2023-10-11 | | Method: | ELECTRON MICROSCOPY (3.57 Å) | | Cite: | The inhibition mechanism of the SUR2A-containing K ATP channel by a regulatory helix.
Nat Commun, 14, 2023
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7Y1N
 | | Structure of SUR2B in complex with Mg-ATP, Mg-ADP, and repaglinide in the partially occluded state | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Isoform SUR2B of ATP-binding cassette sub-family C member 9, ... | | Authors: | Chen, L, Ding, D, Hou, T. | | Deposit date: | 2022-06-08 | | Release date: | 2023-06-14 | | Last modified: | 2023-10-11 | | Method: | ELECTRON MICROSCOPY (3.61 Å) | | Cite: | The inhibition mechanism of the SUR2A-containing K ATP channel by a regulatory helix.
Nat Commun, 14, 2023
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5HLP
 | | X-RAY CRYSTAL STRUCTURE OF GSK3B IN COMPLEX WITH BRD3937 | | Descriptor: | 4-(2-methoxyphenyl)-3,7,7-trimethyl-1,6,7,8-tetrahydro-5H-pyrazolo[3,4-b]quinolin-5-one, Glycogen synthase kinase-3 beta | | Authors: | White, A, Lakshminarasimhan, D, Nadupalli, A, Suto, R.K. | | Deposit date: | 2016-01-15 | | Release date: | 2016-05-25 | | Last modified: | 2016-07-27 | | Method: | X-RAY DIFFRACTION (2.45 Å) | | Cite: | Inhibitors of Glycogen Synthase Kinase 3 with Exquisite Kinome-Wide Selectivity and Their Functional Effects.
Acs Chem.Biol., 11, 2016
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7YXY
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7YXX
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5HZM
 | | Human HMT1 hnRNP methyltransferase-like protein 6 (S. cerevisiae) | | Descriptor: | Protein arginine N-methyltransferase 6, S-ADENOSYL-L-HOMOCYSTEINE, UNKNOWN ATOM OR ION | | Authors: | DONG, A, ZENG, H, WALKER, J.R, Seitova, A, Hutchinson, A, Bountra, C, Arrowsmith, C.H, Edwards, A.M, BROWN, P.J, MIN, J, WU, H, Structural Genomics Consortium (SGC) | | Deposit date: | 2016-02-02 | | Release date: | 2016-02-17 | | Last modified: | 2023-09-27 | | Method: | X-RAY DIFFRACTION (2.02 Å) | | Cite: | Structural basis of arginine asymmetrical dimethylation by PRMT6.
Biochem. J., 473, 2016
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8F36
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8F37
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8EQG
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8EKV
 | | Human PU.1 ETS-Domain (165-270) Bound to d(AATAAGCGGATGTGGG) | | Descriptor: | DNA (5'-D(*AP*AP*TP*AP*AP*GP*CP*GP*GP*AP*TP*GP*TP*GP*GP*G)-3'), DNA (5'-D(*TP*CP*CP*CP*AP*CP*AP*TP*CP*CP*GP*CP*TP*TP*AP*T)-3'), SODIUM ION, ... | | Authors: | Terrell, J.R, Poon, G.M.K. | | Deposit date: | 2022-09-22 | | Release date: | 2023-07-05 | | Last modified: | 2023-10-25 | | Method: | X-RAY DIFFRACTION (1.62 Å) | | Cite: | DNA selection by the master transcription factor PU.1.
Cell Rep, 42, 2023
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