7Y1K

Structure of SUR2A in complex with Mg-ATP, Mg-ADP and repaglinide in the inward-facing conformation

Summary for 7Y1K

• Entry DOI: 10.2210/pdb7y1k/pdb
• EMDB information: 33564
• Descriptor: ATP-binding cassette sub-family C member 9, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... (5 entities in total)
• Functional Keywords: sur2a, abc transporter, repaglinide, membrane protein
• Biological source: Rattus norvegicus (Norway rat)
• Total number of polymer chains: 1
• Total formula weight: 175736.00

Authors

Chen, L.,Ding, D.,Hou, T. (deposition date: 2022-06-08, release date: 2023-06-14, Last modification date: 2023-10-11)

• Primary citation: Ding, D.,Hou, T.,Wei, M.,Wu, J.X.,Chen, L.; The inhibition mechanism of the SUR2A-containing K ATP channel by a regulatory helix.; Nat Commun, 14:3608-3608, 2023; PubMed: 37330603; DOI: 10.1038/s41467-023-39379-4

Experimental method

ELECTRON MICROSCOPY (3.8 Å)