4GBX
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![BU of 4gbx by Molmil](/molmil-images/mine/4gbx) | Crystal structure of an immune complex at pH 6.5 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, HLA class II histocompatibility antigen, DM alpha chain, ... | Authors: | Sethi, D.K, Pos, W, Wucherpfennig, K.W. | Deposit date: | 2012-07-28 | Release date: | 2013-01-16 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Crystal Structure of the HLA-DM-HLA-DR1 Complex Defines Mechanisms for Rapid Peptide Selection. Cell(Cambridge,Mass.), 151, 2012
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7PDZ
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![BU of 7pdz by Molmil](/molmil-images/mine/7pdz) | Structure of capping protein bound to the barbed end of a cytoplasmic actin filament | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Actin, cytoplasmic 1, ... | Authors: | Funk, J, Merino, F, Schacks, M, Rottner, K, Raunser, S, Bieling, P. | Deposit date: | 2021-08-09 | Release date: | 2021-09-01 | Last modified: | 2021-10-06 | Method: | ELECTRON MICROSCOPY (3.8 Å) | Cite: | A barbed end interference mechanism reveals how capping protein promotes nucleation in branched actin networks. Nat Commun, 12, 2021
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7D5X
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![BU of 7d5x by Molmil](/molmil-images/mine/7d5x) | Bovine heart cytochrome c oxidase in a catalytic intermediate, IO10, at 1.74 angstrom resolution | Descriptor: | (1R)-2-{[{[(2S)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL (11E)-OCTADEC-11-ENOATE, (1S)-2-{[(2-AMINOETHOXY)(HYDROXY)PHOSPHORYL]OXY}-1-[(STEAROYLOXY)METHYL]ETHYL (5E,8E,11E,14E)-ICOSA-5,8,11,14-TETRAENOATE, (7R,17E,20E)-4-HYDROXY-N,N,N-TRIMETHYL-9-OXO-7-[(PALMITOYLOXY)METHYL]-3,5,8-TRIOXA-4-PHOSPHAHEXACOSA-17,20-DIEN-1-AMINIUM 4-OXIDE, ... | Authors: | Tsukihara, T, Shimada, A. | Deposit date: | 2020-09-28 | Release date: | 2021-07-21 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.74 Å) | Cite: | Critical roles of the Cu B site in efficient proton pumping as revealed by crystal structures of mammalian cytochrome c oxidase catalytic intermediates. J.Biol.Chem., 297, 2021
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5DTO
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![BU of 5dto by Molmil](/molmil-images/mine/5dto) | Dengue virus full length NS5 complexed with viral Cap 0-RNA and SAH | Descriptor: | 7N-METHYL-8-HYDROGUANOSINE-5'-DIPHOSPHATE, ACETATE ION, MAGNESIUM ION, ... | Authors: | Zhao, Y, Soh, T.S, Lim, S.P, Chung, K.Y, Swaminathan, K, Vasudevan, S.G, Shi, P.-Y, Lescar, J, Luo, D. | Deposit date: | 2015-09-18 | Release date: | 2015-11-25 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (2.603 Å) | Cite: | Molecular basis for specific viral RNA recognition and 2'-O-ribose methylation by the dengue virus nonstructural protein 5 (NS5) Proc.Natl.Acad.Sci.USA, 112, 2015
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7D5W
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![BU of 7d5w by Molmil](/molmil-images/mine/7d5w) | Bovine heart cytochrome c oxidase in a catalytic intermediate of O at 1.84 angstrom resolution | Descriptor: | (1R)-2-{[{[(2S)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL (11E)-OCTADEC-11-ENOATE, (1S)-2-{[(2-AMINOETHOXY)(HYDROXY)PHOSPHORYL]OXY}-1-[(STEAROYLOXY)METHYL]ETHYL (5E,8E,11E,14E)-ICOSA-5,8,11,14-TETRAENOATE, (7R,17E,20E)-4-HYDROXY-N,N,N-TRIMETHYL-9-OXO-7-[(PALMITOYLOXY)METHYL]-3,5,8-TRIOXA-4-PHOSPHAHEXACOSA-17,20-DIEN-1-AMINIUM 4-OXIDE, ... | Authors: | Tsukihara, T, Shimada, A. | Deposit date: | 2020-09-28 | Release date: | 2021-07-21 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.84 Å) | Cite: | Critical roles of the Cu B site in efficient proton pumping as revealed by crystal structures of mammalian cytochrome c oxidase catalytic intermediates. J.Biol.Chem., 297, 2021
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8OV0
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![BU of 8ov0 by Molmil](/molmil-images/mine/8ov0) | MUC5AC CysD7 amino acids 3518-3626 | Descriptor: | CALCIUM ION, CHLORIDE ION, Mucin-5AC | Authors: | Khmelnitsky, L, Milo, A, Dym, O, Fass, D. | Deposit date: | 2023-04-25 | Release date: | 2023-08-16 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Diversity of CysD domains in gel-forming mucins. Febs J., 290, 2023
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5DUI
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7DBN
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![BU of 7dbn by Molmil](/molmil-images/mine/7dbn) | HIV-1 reverse transcriptase mutant Q151M/Y115F/F116Y/M184V/F160M:DNA:dCTP ternary complex | Descriptor: | 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, DNA/RNA (38-MER), GLYCEROL, ... | Authors: | Yasutake, Y, Hattori, S.I, Tamura, N, Maeda, K. | Deposit date: | 2020-10-21 | Release date: | 2021-08-04 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.67 Å) | Cite: | Biochemical and Structural Properties of Entecavir-Resistant Hepatitis B Virus Polymerase with L180M/M204V Mutations. J.Virol., 95, 2021
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7DF8
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![BU of 7df8 by Molmil](/molmil-images/mine/7df8) | full length hNPC1L1-Apo | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Hu, M, Sun, S, Sui, S. | Deposit date: | 2020-11-06 | Release date: | 2021-08-04 | Method: | ELECTRON MICROSCOPY (3.03 Å) | Cite: | Structural insights into the mechanism of human NPC1L1-mediated cholesterol uptake. Sci Adv, 7, 2021
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7PJT
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![BU of 7pjt by Molmil](/molmil-images/mine/7pjt) | Structure of the 70S ribosome with tRNAs in hybrid state 1 (H1) | Descriptor: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | Authors: | Petrychenko, V, Peng, B.Z, Schwarzer, A.C, Peske, F, Rodnina, M.V, Fischer, N. | Deposit date: | 2021-08-24 | Release date: | 2021-10-20 | Last modified: | 2024-04-24 | Method: | ELECTRON MICROSCOPY (6 Å) | Cite: | Structural mechanism of GTPase-powered ribosome-tRNA movement. Nat Commun, 12, 2021
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6ZPL
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![BU of 6zpl by Molmil](/molmil-images/mine/6zpl) | Inward-open structure of human glycine transporter 1 in complex with a benzoylisoindoline inhibitor, sybody Sb_GlyT1#7 and bound Na and Cl ions. | Descriptor: | CHLORIDE ION, Endoglucanase H, SODIUM ION, ... | Authors: | Shahsavar, A, Stohler, P, Bourenkov, G, Zimmermann, I, Siegrist, M, Guba, W, Pinard, E, Sinning, S, Seeger, M.A, Schneider, T.R, Dawson, R.J.P, Nissen, P. | Deposit date: | 2020-07-08 | Release date: | 2021-03-17 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (3.945 Å) | Cite: | Structural insights into the inhibition of glycine reuptake. Nature, 591, 2021
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7PJU
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![BU of 7pju by Molmil](/molmil-images/mine/7pju) | Structure of the 70S ribosome with tRNAs in hybrid state 2 (H2) | Descriptor: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | Authors: | Petrychenko, V, Peng, B.Z, Schwarzer, A.C, Peske, F, Rodnina, M.V, Fischer, N. | Deposit date: | 2021-08-24 | Release date: | 2021-11-17 | Last modified: | 2024-04-24 | Method: | ELECTRON MICROSCOPY (9.5 Å) | Cite: | Structural mechanism of GTPase-powered ribosome-tRNA movement. Nat Commun, 12, 2021
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8P4B
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![BU of 8p4b by Molmil](/molmil-images/mine/8p4b) | Structural insights into human co-transcriptional capping - structure 2 | Descriptor: | DNA (35-MER), DNA (5'-D(P*AP*GP*CP*GP*GP*CP*GP*GP*AP*GP*CP*CP*AP*GP*CP*AP*GP*GP*GP*AP*GP*CP*TP*G)-3'), DNA-directed RNA polymerase II subunit E, ... | Authors: | Garg, G, Dienemann, C, Farnung, L, Schwarz, J, Linden, A, Urlaub, H, Cramer, P. | Deposit date: | 2023-05-20 | Release date: | 2023-08-16 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Structural insights into human co-transcriptional capping. Mol.Cell, 83, 2023
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7DEG
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![BU of 7deg by Molmil](/molmil-images/mine/7deg) | Cryo-EM structure of a heme-copper terminal oxidase dimer provides insights into its catalytic mechanism | Descriptor: | (1R)-2-{[{[(2S)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL (11E)-OCTADEC-11-ENOATE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, 2-[(2~{E},6~{E},10~{Z},14~{Z},18~{Z},23~{R})-3,7,11,15,19,23,27-heptamethyloctacosa-2,6,10,14,18-pentaenyl]naphthalene-1,4-dione, ... | Authors: | Fei, S, Hartmut, M, Yun, Z, Guoliang, Z, Shuangbo, Z. | Deposit date: | 2020-11-04 | Release date: | 2021-08-04 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | The Unusual Homodimer of a Heme-Copper Terminal Oxidase Allows Itself to Utilize Two Electron Donors. Angew.Chem.Int.Ed.Engl., 60, 2021
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7DBM
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![BU of 7dbm by Molmil](/molmil-images/mine/7dbm) | HIV-1 reverse transcriptase mutant Q151M/Y115F/F116Y/M184V:DNA:dGTP ternary complex | Descriptor: | 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, DNA/RNA (38-MER), GLYCEROL, ... | Authors: | Yasutake, Y, Hattori, S.I, Tamura, N, Maeda, K. | Deposit date: | 2020-10-21 | Release date: | 2021-08-04 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.43 Å) | Cite: | Biochemical and Structural Properties of Entecavir-Resistant Hepatitis B Virus Polymerase with L180M/M204V Mutations. J.Virol., 95, 2021
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4FZ1
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![BU of 4fz1 by Molmil](/molmil-images/mine/4fz1) | |
7PQD
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![BU of 7pqd by Molmil](/molmil-images/mine/7pqd) | Cryo-EM structure of the dimeric Rhodobacter sphaeroides RC-LH1 core complex at 2.9 A: the structural basis for dimerisation | Descriptor: | (2R,5R,11R,14R)-5,8,11-trihydroxy-5,11-dioxido-17-oxo-2,14-bis(tetradecanoyloxy)-4,6,10,12,16-pentaoxa-5,11-diphosphatriacont-1-yl tetradecanoate, 1,2-DI-O-ACYL-3-O-[6-DEOXY-6-SULFO-ALPHA-D-GLUCOPYRANOSYL]-SN-GLYCEROL, 1,2-Distearoyl-sn-glycerophosphoethanolamine, ... | Authors: | Qian, P, Hunter, C.N. | Deposit date: | 2021-09-17 | Release date: | 2021-11-24 | Last modified: | 2022-12-07 | Method: | ELECTRON MICROSCOPY (2.9 Å) | Cite: | Cryo-EM structure of the dimeric Rhodobacter sphaeroides RC-LH1 core complex at 2.9 angstrom : the structural basis for dimerisation. Biochem.J., 478, 2021
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5E13
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![BU of 5e13 by Molmil](/molmil-images/mine/5e13) | Crystal structure of Eosinophil-derived neurotoxin in complex with the triazole double-headed ribonucleoside 11c | Descriptor: | 3'-{4-[(4-amino-2-oxopyrimidin-1(2H)-yl)methyl]-1H-1,2,3-triazol-1-yl}-3'-deoxyadenosine, Non-secretory ribonuclease | Authors: | Chatzileontiadou, D.S.M, Stravodimos, G.A, Kantsadi, A.L, Leonidas, D.D. | Deposit date: | 2015-09-29 | Release date: | 2015-11-18 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.34 Å) | Cite: | Triazole double-headed ribonucleosides as inhibitors of eosinophil derived neurotoxin. Bioorg.Chem., 63, 2015
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4G0I
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![BU of 4g0i by Molmil](/molmil-images/mine/4g0i) | Glutathionyl-Hydroquinone Reductase, YqjG of Escherichia coli | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, SULFATE ION, protein yqjG | Authors: | Green, A.R, Hayes, R.P, Xun, L, Kang, C. | Deposit date: | 2012-07-09 | Release date: | 2012-09-12 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | Structural understanding of the glutathione-dependent reduction mechanism of glutathionyl-hydroquinone reductases. J.Biol.Chem., 287, 2012
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4G0W
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![BU of 4g0w by Molmil](/molmil-images/mine/4g0w) | Human topoisomerase iibeta in complex with DNA and ametantrone | Descriptor: | 1,4-bis({2-[(2-hydroxyethyl)amino]ethyl}amino)anthracene-9,10-dione, DNA (5'-D(P*AP*GP*CP*CP*GP*AP*GP*C)-3'), DNA (5'-D(P*TP*GP*CP*AP*GP*CP*TP*CP*GP*GP*CP*T)-3'), ... | Authors: | Wu, C.C, Li, T.K, Li, Y.C, Chan, N.L. | Deposit date: | 2012-07-10 | Release date: | 2013-07-17 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.696 Å) | Cite: | On the structural basis and design guidelines for type II topoisomerase-targeting anticancer drugs Nucleic Acids Res., 41, 2013
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8P4C
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![BU of 8p4c by Molmil](/molmil-images/mine/8p4c) | Structural insights into human co-transcriptional capping - structure 3 | Descriptor: | DNA (32-MER), DNA (41-MER), DNA-directed RNA polymerase II subunit E, ... | Authors: | Garg, G, Dienemann, C, Farnung, L, Schwarz, J, Linden, A, Urlaub, H, Cramer, P. | Deposit date: | 2023-05-20 | Release date: | 2023-08-16 | Method: | ELECTRON MICROSCOPY (3.8 Å) | Cite: | Structural insights into human co-transcriptional capping. Mol.Cell, 83, 2023
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4FZ0
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![BU of 4fz0 by Molmil](/molmil-images/mine/4fz0) | |
7ABO
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![BU of 7abo by Molmil](/molmil-images/mine/7abo) | |
7A43
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![BU of 7a43 by Molmil](/molmil-images/mine/7a43) | |
7A42
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![BU of 7a42 by Molmil](/molmil-images/mine/7a42) | |