7DBM

HIV-1 reverse transcriptase mutant Q151M/Y115F/F116Y/M184V:DNA:dGTP ternary complex

Summary for 7DBM

• Entry DOI: 10.2210/pdb7dbm/pdb
• Descriptor: Protease, HIV-1 RT p51 subunit, DNA/RNA (38-MER), ... (7 entities in total)
• Functional Keywords: entecavir 5'-triphosphate, hiv-1, hbv, reverse transcriptase, drug resistance, transferase-dna complex, replication, transferase/dna
• Biological source: Human immunodeficiency virus 1; More
• Total number of polymer chains: 6
• Total formula weight: 256698.19

Authors

Yasutake, Y.,Hattori, S.I.,Tamura, N.,Maeda, K. (deposition date: 2020-10-21, release date: 2021-08-04, Last modification date: 2023-11-29)

• Primary citation: Nakajima, S.,Watashi, K.,Kato, T.,Muramatsu, M.,Wakita, T.,Tamura, N.,Hattori, S.I.,Maeda, K.,Mitsuya, H.,Yasutake, Y.,Toyoda, T.; Biochemical and Structural Properties of Entecavir-Resistant Hepatitis B Virus Polymerase with L180M/M204V Mutations.; J.Virol., 95:e0240120-e0240120, 2021; PubMed: 34076480; DOI: 10.1128/JVI.02401-20

Experimental method

X-RAY DIFFRACTION (2.43 Å)