PDB: 72236 resultsInfo pagesStatus searchChemie searchBIRD

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6FYI	X-ray Structure of CLK2-KD(130-496)/TG003 at 2.6A Descriptor: (1~{Z})-1-(3-ethyl-5-methoxy-1,3-benzothiazol-2-ylidene)propan-2-one, Dual specificity protein kinase CLK2 Authors: Kallen, J. Deposit date: 2018-03-12 Release date: 2018-07-18 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (2.6 Å) Cite: X-ray Structures and Feasibility Assessment of CLK2 Inhibitors for Phelan-McDermid Syndrome. ChemMedChem, 13, 2018
6FYP	X-RAY STRUCTURE OF CLK3-KD(GP-[275-632], NON-PHOS.)/CX-4945 AT 2.29A Descriptor: 5-[(3-chlorophenyl)amino]benzo[c][2,6]naphthyridine-8-carboxylic acid, Dual specificity protein kinase CLK3 Authors: Kallen, J. Deposit date: 2018-03-12 Release date: 2018-07-18 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (2.29 Å) Cite: X-ray Structures and Feasibility Assessment of CLK2 Inhibitors for Phelan-McDermid Syndrome. ChemMedChem, 13, 2018
8JJ8	Cryo-EM structure of the beta2AR-mBRIL/1b3 Fab/Glue complex with a partial agonist Descriptor: Beta-2 adrenergic receptor,Soluble cytochrome b562, ~{N}-[5-[(1~{R})-2-[[(2~{R})-1-(4-methoxyphenyl)propan-2-yl]amino]-1-oxidanyl-ethyl]-2-oxidanyl-phenyl]methanamide Authors: He, B.B, Zhong, Y.X, Guo, Q, Tao, Y.Y. Deposit date: 2023-05-29 Release date: 2023-09-06 Last modified: 2024-01-03 Method: ELECTRON MICROSCOPY (3.2 Å) Cite: A method for structure determination of GPCRs in various states. Nat.Chem.Biol., 20, 2024
5Z5W	VFR12 in complex with LPS micelles Descriptor: Peptide from Prothrombin Authors: Saravanan, R, Schmidtchen, A. Deposit date: 2018-01-21 Release date: 2018-03-07 Last modified: 2024-05-01 Method: SOLUTION NMR Cite: Structural basis for endotoxin neutralisation and anti-inflammatory activity of thrombin-derived C-terminal peptides. Nat Commun, 9, 2018
6NT0	Catalase 3 from N.Crassa in ferrous state, X-ray reduced (1.315 MGy) Descriptor: 1,2-ETHANEDIOL, ACETATE ION, Catalase-3, ... Authors: Zarate-Romero, A, Rudino-Pinera, E, Stojanoff, V. Deposit date: 2019-01-27 Release date: 2019-05-01 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (2.2 Å) Cite: X-ray driven reduction of Cpd I of Catalase-3 from N. crassa reveals differential sensitivity of active sites and formation of ferrous state. Arch.Biochem.Biophys., 666, 2019
6FYR	X-RAY STRUCTURE OF CLK3-KD(GP-[275-632], NON-PHOS.)/Cpd-2 AT 1.42A Descriptor: 6-~{tert}-butyl-~{N}-[6-(1~{H}-pyrazol-4-yl)-1~{H}-imidazo[1,2-a]pyridin-2-yl]pyridine-3-carboxamide, Dual specificity protein kinase CLK3 Authors: Kallen, J. Deposit date: 2018-03-12 Release date: 2018-07-18 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (1.42 Å) Cite: X-ray Structures and Feasibility Assessment of CLK2 Inhibitors for Phelan-McDermid Syndrome. ChemMedChem, 13, 2018
5ZGG	NMR structure of p75NTR transmembrane domain in complex with NSC49652 Descriptor: (2E)-1-(2-hydroxyphenyl)-3-(pyridin-3-yl)prop-2-en-1-one, Tumor necrosis factor receptor superfamily member 16 Authors: Lin, Z, Ibanez, C. Deposit date: 2018-03-08 Release date: 2019-03-13 Last modified: 2019-09-25 Method: SOLUTION NMR Cite: A Small Molecule Targeting the Transmembrane Domain of Death Receptor p75NTRInduces Melanoma Cell Death and Reduces Tumor Growth. Cell Chem Biol, 25, 2018
5Z5X	HVF18 in complex with LPS micelles Descriptor: Peptide from Prothrombin Authors: Saravanan, R, Schmidtchen, A. Deposit date: 2018-01-21 Release date: 2018-03-07 Last modified: 2024-05-01 Method: SOLUTION NMR Cite: Structural basis for endotoxin neutralisation and anti-inflammatory activity of thrombin-derived C-terminal peptides. Nat Commun, 9, 2018
3UF2	Crystal structure of the human Colony-Stimulating Factor 1 (hCSF-1) cytokine Descriptor: Macrophage colony-stimulating factor 1 Authors: Elegheert, J, Savvides, S.N. Deposit date: 2011-10-31 Release date: 2012-08-22 Last modified: 2013-07-17 Method: X-RAY DIFFRACTION (2.75 Å) Cite: Allosteric competitive inactivation of hematopoietic CSF-1 signaling by the viral decoy receptor BARF1 Nat.Struct.Mol.Biol., 19, 2012
3LUZ	Crystal structure of extragenic suppressor protein suhB from Bartonella henselae, via combined iodide SAD molecular replacement Descriptor: Extragenic suppressor protein suhB, IODIDE ION, MAGNESIUM ION Authors: Seattle Structural Genomics Center for Infectious Disease (SSGCID) Deposit date: 2010-02-18 Release date: 2010-03-02 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (2.05 Å) Cite: SAD phasing using iodide ions in a high-throughput structural genomics environment. J Struct Funct Genomics, 12, 2011
3UF5	Crystal structure of the mouse Colony-Stimulating Factor 1 (mCSF-1) cytokine Descriptor: CALCIUM ION, Macrophage colony-stimulating factor 1 Authors: Elegheert, J, Bracke, N, Bekaert, A, Savvides, S.N. Deposit date: 2011-10-31 Release date: 2012-08-22 Last modified: 2013-07-17 Method: X-RAY DIFFRACTION (2.8 Å) Cite: Allosteric competitive inactivation of hematopoietic CSF-1 signaling by the viral decoy receptor BARF1 Nat.Struct.Mol.Biol., 19, 2012
3UEZ	Crystal structure of the human Colony-Stimulating Factor 1 (hCSF-1) cytokine in complex with the viral receptor BARF1 Descriptor: Macrophage colony-stimulating factor 1, Secreted protein BARF1, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose Authors: Elegheert, J, Bracke, N, Savvides, S.N. Deposit date: 2011-10-31 Release date: 2012-08-22 Last modified: 2020-07-29 Method: X-RAY DIFFRACTION (3.414 Å) Cite: Allosteric competitive inactivation of hematopoietic CSF-1 signaling by the viral decoy receptor BARF1 Nat.Struct.Mol.Biol., 19, 2012
3S55	Crystal structure of a putative short-chain dehydrogenase/reductase from Mycobacterium abscessus bound to NAD Descriptor: CALCIUM ION, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, Putative short-chain dehydrogenase/reductase Authors: Seattle Structural Genomics Center for Infectious Disease (SSGCID) Deposit date: 2011-05-20 Release date: 2011-06-08 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Mycofactocin-associated mycobacterial dehydrogenases with non-exchangeable NAD cofactors. Sci Rep, 7, 2017
3UXF	Structure of the fimbrial protein FimP from Actonomyces oris Descriptor: CALCIUM ION, Fimbrial subunit type 1 Authors: Persson, K. Deposit date: 2011-12-05 Release date: 2012-11-28 Last modified: 2018-01-24 Method: X-RAY DIFFRACTION (1.603 Å) Cite: The Pilin Protein FimP from Actinomyces oris: Crystal Structure and Sequence Analyses. Plos One, 7, 2012
3NF4	Crystal structure of acyl-CoA dehydrogenase from Mycobacterium thermoresistibile bound to flavin adenine dinucleotide Descriptor: FLAVIN-ADENINE DINUCLEOTIDE, SODIUM ION, acyl-CoA dehydrogenase Authors: Seattle Structural Genomics Center for Infectious Disease (SSGCID) Deposit date: 2010-06-09 Release date: 2010-06-23 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (2.35 Å) Cite: Increasing the structural coverage of tuberculosis drug targets. Tuberculosis (Edinb), 95, 2015
3PXX	Crystal structure of carveol dehydrogenase from Mycobacterium avium bound to nicotinamide adenine dinucleotide Descriptor: Carveol dehydrogenase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE Authors: Seattle Structural Genomics Center for Infectious Disease (SSGCID) Deposit date: 2010-12-10 Release date: 2010-12-29 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (2 Å) Cite: Mycofactocin-associated mycobacterial dehydrogenases with non-exchangeable NAD cofactors. Sci Rep, 7, 2017
3OA3	Crystal structure of a putative deoxyribose-phosphate aldolase from Coccidioides immitis Descriptor: ACETATE ION, aldolase Authors: Seattle Structural Genomics Center for Infectious Disease (SSGCID) Deposit date: 2010-08-04 Release date: 2010-08-18 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (1.6 Å) Cite: Crystal structure of an unknown aldolase from Coccidioides immitis To be Published
3NWO	Crystal structure of Proline iminopeptidase Mycobacterium smegmatis Descriptor: 1,2-ETHANEDIOL, GLYCEROL, MAGNESIUM ION, ... Authors: Seattle Structural Genomics Center for Infectious Disease (SSGCID) Deposit date: 2010-07-09 Release date: 2010-08-04 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Increasing the structural coverage of tuberculosis drug targets. Tuberculosis (Edinb), 95, 2015
3OC7	Crystal structure of an enoyl-CoA hydratase from Mycobacterium avium Descriptor: 1,2-ETHANEDIOL, Enoyl-CoA hydratase Authors: Seattle Structural Genomics Center for Infectious Disease (SSGCID) Deposit date: 2010-08-09 Release date: 2010-08-18 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (1.5 Å) Cite: Increasing the structural coverage of tuberculosis drug targets. Tuberculosis (Edinb), 95, 2015
3NFW	Crystal structure of nitrilotriacetate monooxygenase component B (A0R521 homolog) from Mycobacterium thermoresistibile Descriptor: Flavin reductase-like, FMN-binding protein, GLYCEROL Authors: Seattle Structural Genomics Center for Infectious Disease (SSGCID) Deposit date: 2010-06-10 Release date: 2010-06-23 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (1.6 Å) Cite: Structure of nitrilotriacetate monooxygenase component B from Mycobacterium thermoresistibile. Acta Crystallogr.,Sect.F, 67, 2011
3NDN	Crystal structure of O-succinylhomoserine sulfhydrylase from Mycobacterium tuberculosis covalently bound to pyridoxal-5-phosphate Descriptor: O-succinylhomoserine sulfhydrylase Authors: Seattle Structural Genomics Center for Infectious Disease (SSGCID) Deposit date: 2010-06-07 Release date: 2010-06-16 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (1.85 Å) Cite: Increasing the structural coverage of tuberculosis drug targets. Tuberculosis (Edinb), 95, 2015
3OC9	Crystal structure of putative UDP-N-acetylglucosamine pyrophosphorylase from Entamoeba histolytica Descriptor: 1,2-ETHANEDIOL, SULFATE ION, UDP-N-acetylglucosamine pyrophosphorylase Authors: Seattle Structural Genomics Center for Infectious Disease (SSGCID) Deposit date: 2010-08-09 Release date: 2010-08-18 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Structure of uridine diphosphate N-acetylglucosamine pyrophosphorylase from Entamoeba histolytica. Acta Crystallogr F Struct Biol Commun, 71, 2015
3O38	Crystal structure of a short chain dehydrogenase from Mycobacterium smegmatis Descriptor: SODIUM ION, Short chain dehydrogenase Authors: Seattle Structural Genomics Center for Infectious Disease (SSGCID) Deposit date: 2010-07-23 Release date: 2010-08-11 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (1.95 Å) Cite: Increasing the structural coverage of tuberculosis drug targets. Tuberculosis (Edinb), 95, 2015
3P0X	Crystal structure of isocitrate lyase from Brucella melitensis, bound to magnesium isocitrate Descriptor: 1,2-ETHANEDIOL, ISOCITRIC ACID, Isocitrate lyase, ... Authors: Seattle Structural Genomics Center for Infectious Disease (SSGCID) Deposit date: 2010-09-29 Release date: 2010-10-27 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (2.35 Å) Cite: Crystal structure of isocitrate lyase from Brucella melitensis, bound to magnesium isocitrate To be Published
3MXU	Crystal structure of glycine cleavage system protein H from Bartonella henselae Descriptor: 1,2-ETHANEDIOL, CITRIC ACID, Glycine cleavage system H protein, ... Authors: Seattle Structural Genomics Center for Infectious Disease (SSGCID) Deposit date: 2010-05-07 Release date: 2010-05-26 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Crystal structure of glycine cleavage system protein H from Bartonella henselae To be Published

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