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7NY8
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BU of 7ny8 by Molmil
Affimer K69 - KRAS protein complex
Descriptor: Affimer K69, GTPase KRas, GUANOSINE-5'-DIPHOSPHATE, ...
Authors:Turner, A.L, Trinh, C.H, Haza, K.Z, Rao, A, Martin, H.L, Tiede, C, Edwards, T.A, McPherson, M.J, Tomlinson, D.C.
Deposit date:2021-03-21
Release date:2021-07-07
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:RAS-inhibiting biologics identify and probe druggable pockets including an SII-alpha 3 allosteric site.
Nat Commun, 12, 2021
7OE0
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BU of 7oe0 by Molmil
E. coli pre-30S delta rbfA ribosomal subunit class F
Descriptor: 16S rRNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ...
Authors:Maksimova, E, Korepanov, A, Baymukhametov, T, Kravchenko, O, Stolboushkina, E.
Deposit date:2021-04-30
Release date:2021-07-14
Last modified:2024-07-10
Method:ELECTRON MICROSCOPY (2.69 Å)
Cite:RbfA Is Involved in Two Important Stages of 30S Subunit Assembly: Formation of the Central Pseudoknot and Docking of Helix 44 to the Decoding Center.
Int J Mol Sci, 22, 2021
7OE1
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BU of 7oe1 by Molmil
30S ribosomal subunit from E. coli
Descriptor: 16S rRNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ...
Authors:Maksimova, E, Korepanov, A, Baymukhametov, T, Kravchenko, O, Stolboushkina, E.
Deposit date:2021-04-30
Release date:2021-07-14
Last modified:2024-07-10
Method:ELECTRON MICROSCOPY (3.05 Å)
Cite:RbfA Is Involved in Two Important Stages of 30S Subunit Assembly: Formation of the Central Pseudoknot and Docking of Helix 44 to the Decoding Center.
Int J Mol Sci, 22, 2021
7OI0
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BU of 7oi0 by Molmil
E.coli delta rbfA pre-30S ribosomal subunit class D
Descriptor: 16S rRNA, 30S ribosomal protein S11, 30S ribosomal protein S12, ...
Authors:Maksimova, E, Korepanov, A, Baymukhametov, T, Kravchenko, O, Stolboushkina, E.
Deposit date:2021-05-11
Release date:2021-07-14
Last modified:2024-07-10
Method:ELECTRON MICROSCOPY (2.76 Å)
Cite:RbfA Is Involved in Two Important Stages of 30S Subunit Assembly: Formation of the Central Pseudoknot and Docking of Helix 44 to the Decoding Center.
Int J Mol Sci, 22, 2021
2WY1
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BU of 2wy1 by Molmil
Crystal structure of rat angiotensinogen in P321 space group
Descriptor: ANGIOTENSINOGEN
Authors:Zhou, A, Wei, Z, Carrell, R.W, Read, R.J.
Deposit date:2009-11-11
Release date:2010-10-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.15 Å)
Cite:A Redox Switch in Angiotensinogen Modulates Angiotensin Release.
Nature, 468, 2010
2WXW
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BU of 2wxw by Molmil
Crystal structure of human angiotensinogen
Descriptor: ANGIOTENSINOGEN
Authors:Zhou, A, Wei, Z, Carrell, R.W, Read, R.J.
Deposit date:2009-11-11
Release date:2010-10-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:A Redox Switch in Angiotensinogen Modulates Angiotensin Release.
Nature, 468, 2010
1D6K
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BU of 1d6k by Molmil
NMR SOLUTION STRUCTURE OF THE 5S RRNA E-LOOP/L25 COMPLEX
Descriptor: 5S RRNA E-LOOP (5SE), RIBOSOMAL PROTEIN L25
Authors:Stoldt, M, Wohnert, J, Ohlenschlager, O, Gorlach, M, Brown, L.R.
Deposit date:1999-10-14
Release date:1999-11-22
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:The NMR structure of the 5S rRNA E-domain-protein L25 complex shows preformed and induced recognition.
EMBO J., 18, 1999
1N1M
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BU of 1n1m by Molmil
Human Dipeptidyl Peptidase IV/CD26 in complex with an inhibitor
Descriptor: 2-AMINO-3-METHYL-1-PYRROLIDIN-1-YL-BUTAN-1-ONE, 2-acetamido-2-deoxy-alpha-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-alpha-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Rasmussen, H.B, Branner, S, Wiberg, F.C, Wagtmann, N.R.
Deposit date:2002-10-18
Release date:2002-12-27
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structure of human dipeptidyl peptidase IV/CD26 in complex with a substrate analogue
Nat.Struct.Biol., 10, 2003
6Y69
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BU of 6y69 by Molmil
Cryo-EM structure of an Escherichia coli 70S ribosome in complex with antibiotic TetracenomycinX
Descriptor: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Wieland, M, Wilson, D.N.
Deposit date:2020-02-26
Release date:2020-07-01
Last modified:2023-11-08
Method:ELECTRON MICROSCOPY (2.86 Å)
Cite:Tetracenomycin X inhibits translation by binding within the ribosomal exit tunnel.
Nat.Chem.Biol., 16, 2020
2WJY
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BU of 2wjy by Molmil
Crystal structure of the complex between human nonsense mediated decay factors UPF1 and UPF2 Orthorhombic form
Descriptor: REGULATOR OF NONSENSE TRANSCRIPTS 1, SULFATE ION, ZINC ION
Authors:Clerici, M, Mourao, A, Gutsche, I, Gehring, N.H, Hentze, M.W, Kulozik, A, Kadlec, J, Sattler, M, Cusack, S.
Deposit date:2009-06-01
Release date:2009-07-07
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Unusual Bipartite Mode of Interaction between the Nonsense-Mediated Decay Factors, Upf1 and Upf2.
Embo J., 28, 2009
1NDV
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BU of 1ndv by Molmil
Crystal Structure of Adenosine Deaminase complexed with FR117016
Descriptor: Adenosine deaminase, N''-(4-(5-((1H-BENZIMIDAZOL-2-YLAMINO)METHYL)-2-THIENYL)-1,3-THIAZOL-2-YL)GUANIDINE, ZINC ION
Authors:Kinoshita, T.
Deposit date:2002-12-09
Release date:2003-12-09
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:A highly potent non-nucleoside adenosine deaminase inhibitor: efficient drug discovery by intentional lead hybridization
J.Am.Chem.Soc., 126, 2004
6YDP
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BU of 6ydp by Molmil
55S mammalian mitochondrial ribosome with mtEFG1 and P site fMet-tRNAMet (POST)
Descriptor: 12S rRNA, 28S ribosomal protein S16, mitochondrial, ...
Authors:Kummer, E, Ban, N.
Deposit date:2020-03-20
Release date:2020-07-15
Last modified:2020-08-12
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Structural insights into mammalian mitochondrial translation elongation catalyzed by mtEFG1.
Embo J., 39, 2020
7O19
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BU of 7o19 by Molmil
Cryo-EM structure of an Escherichia coli TnaC-ribosome complex stalled in response to L-tryptophan
Descriptor: 30S ribosomal protein S10, 30S ribosomal protein S11, 30S ribosomal protein S12, ...
Authors:van der Stel, A.X, Gordon, E.R, Sengupta, A, Martinez, A.K, Klepacki, D, Perry, T.N, Herrero del Valle, A, Vazquez-Laslop, N, Sachs, M.S, Cruz-Vera, L.R, Innis, C.A.
Deposit date:2021-03-29
Release date:2021-09-01
Last modified:2024-04-24
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Structural basis for the tryptophan sensitivity of TnaC-mediated ribosome stalling.
Nat Commun, 12, 2021
7O1A
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BU of 7o1a by Molmil
Cryo-EM structure of an Escherichia coli TnaC(R23F)-ribosome complex stalled in response to L-tryptophan
Descriptor: 30S ribosomal protein S10, 30S ribosomal protein S11, 30S ribosomal protein S12, ...
Authors:van der Stel, A.X, Gordon, E.R, Sengupta, A, Martinez, A.K, Klepacki, D, Perry, T.N, Herrero del Valle, A, Vazquez-Laslop, N, Sachs, M.S, Cruz-Vera, L.R, Innis, C.A.
Deposit date:2021-03-29
Release date:2021-09-01
Last modified:2024-04-24
Method:ELECTRON MICROSCOPY (2.4 Å)
Cite:Structural basis for the tryptophan sensitivity of TnaC-mediated ribosome stalling.
Nat Commun, 12, 2021
7O1C
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BU of 7o1c by Molmil
Cryo-EM structure of an Escherichia coli TnaC(R23F)-ribosome-RF2 complex stalled in response to L-tryptophan
Descriptor: 30S ribosomal protein S10, 30S ribosomal protein S11, 30S ribosomal protein S12, ...
Authors:van der Stel, A.X, Gordon, E.R, Sengupta, A, Martinez, A.K, Klepacki, D, Perry, T.N, Herrero del Valle, A, Vazquez-Laslop, N, Sachs, M.S, Cruz-Vera, L.R, Innis, C.A.
Deposit date:2021-03-29
Release date:2021-09-01
Last modified:2024-04-24
Method:ELECTRON MICROSCOPY (2.6 Å)
Cite:Structural basis for the tryptophan sensitivity of TnaC-mediated ribosome stalling.
Nat Commun, 12, 2021
1C4Z
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BU of 1c4z by Molmil
STRUCTURE OF AN E6AP-UBCH7 COMPLEX: INSIGHTS INTO THE UBIQUITINATION PATHWAY
Descriptor: UBIQUITIN CONJUGATING ENZYME E2, UBIQUITIN-PROTEIN LIGASE E3A
Authors:Huang, L, Kinnucan, E, Wang, G, Beaudenon, S, Howley, P.M, Huibregtse, J.M, Pavletich, N.P.
Deposit date:1999-10-14
Release date:1999-11-17
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structure of an E6AP-UbcH7 complex: insights into ubiquitination by the E2-E3 enzyme cascade.
Science, 286, 1999
7OI9
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BU of 7oi9 by Molmil
Cryo-EM structure of late human 39S mitoribosome assembly intermediates, state 3B
Descriptor: 16S rRNA, 39S ribosomal protein L10, mitochondrial, ...
Authors:Cheng, J, Berninghausen, O, Beckmann, R.
Deposit date:2021-05-11
Release date:2021-09-15
Last modified:2024-07-10
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:A distinct assembly pathway of the human 39S late pre-mitoribosome.
Nat Commun, 12, 2021
6Y9B
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BU of 6y9b by Molmil
Cryo-EM structure of trimeric human STEAP1 bound to three Fab120.545 fragments
Descriptor: 1,2-DIMYRISTOYL-SN-GLYCERO-3-PHOSPHATE, Fab120.545 heavy chain, Fab120.545 light chain, ...
Authors:Oosterheert, W, Gros, P.
Deposit date:2020-03-06
Release date:2020-05-20
Last modified:2020-07-22
Method:ELECTRON MICROSCOPY (2.97 Å)
Cite:Cryo-electron microscopy structure and potential enzymatic function of human six-transmembrane epithelial antigen of the prostate 1 (STEAP1).
J.Biol.Chem., 295, 2020
7OIA
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BU of 7oia by Molmil
Cryo-EM structure of late human 39S mitoribosome assembly intermediates, state 3C
Descriptor: 16S rRNA, 39S ribosomal protein L10, mitochondrial, ...
Authors:Cheng, J, Berninghausen, O, Beckmann, R.
Deposit date:2021-05-11
Release date:2021-09-15
Last modified:2024-07-10
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:A distinct assembly pathway of the human 39S late pre-mitoribosome.
Nat Commun, 12, 2021
7OI7
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BU of 7oi7 by Molmil
Cryo-EM structure of late human 39S mitoribosome assembly intermediates, state 2
Descriptor: 16S rRNA, 39S ribosomal protein L10, mitochondrial, ...
Authors:Cheng, J, Berninghausen, O, Beckmann, R.
Deposit date:2021-05-11
Release date:2021-09-15
Last modified:2024-07-10
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:A distinct assembly pathway of the human 39S late pre-mitoribosome.
Nat Commun, 12, 2021
7OIE
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BU of 7oie by Molmil
Cryo-EM structure of late human 39S mitoribosome assembly intermediates, state 5B
Descriptor: 16S rRNA, 39S ribosomal protein L10, mitochondrial, ...
Authors:Cheng, J, Berninghausen, O, Beckmann, R.
Deposit date:2021-05-11
Release date:2021-09-15
Last modified:2024-07-10
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:A distinct assembly pathway of the human 39S late pre-mitoribosome.
Nat Commun, 12, 2021
7OIC
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BU of 7oic by Molmil
Cryo-EM structure of late human 39S mitoribosome assembly intermediates, state 4
Descriptor: 16S rRNA, 39S ribosomal protein L10, mitochondrial, ...
Authors:Cheng, J, Berninghausen, O, Beckmann, R.
Deposit date:2021-05-11
Release date:2021-09-15
Last modified:2021-10-13
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:A distinct assembly pathway of the human 39S late pre-mitoribosome.
Nat Commun, 12, 2021
7OIB
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BU of 7oib by Molmil
Cryo-EM structure of late human 39S mitoribosome assembly intermediates, state 3D
Descriptor: 16S rRNA, 39S ribosomal protein L10, mitochondrial, ...
Authors:Cheng, J, Berninghausen, O, Beckmann, R.
Deposit date:2021-05-11
Release date:2021-09-15
Last modified:2024-07-10
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:A distinct assembly pathway of the human 39S late pre-mitoribosome.
Nat Commun, 12, 2021
7OJ0
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BU of 7oj0 by Molmil
Cryo-EM structure of 70S ribosome stalled with TnaC peptide and RF2
Descriptor: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
Authors:Su, T, Kudva, R, Becker, T, Berninghausen, O, Heijne, G, Cheng, J, Beckmann, R.
Deposit date:2021-05-13
Release date:2021-09-15
Last modified:2024-04-24
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Structural basis of l-tryptophan-dependent inhibition of release factor 2 by the TnaC arrest peptide.
Nucleic Acids Res., 49, 2021
7OIZ
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BU of 7oiz by Molmil
Cryo-EM structure of 70S ribosome stalled with TnaC peptide
Descriptor: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
Authors:Su, T, Kudva, R, Becker, T, Berninghausen, O, Heijne, G, Cheng, J, Beckmann, R.
Deposit date:2021-05-13
Release date:2021-09-15
Last modified:2024-04-24
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Structural basis of l-tryptophan-dependent inhibition of release factor 2 by the TnaC arrest peptide.
Nucleic Acids Res., 49, 2021

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