PDB: 72960 resultsInfo pagesStatus searchChemie searchBIRD

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3G4S	Co-crystal structure of Tiamulin bound to the large ribosomal subunit Descriptor: 23S ribosomal RNA, 50S ribosomal protein L10, 50S ribosomal protein L10e, ... Authors: Gurel, G, Blaha, G, Moore, P.B, Steitz, T.A. Deposit date: 2009-02-04 Release date: 2009-04-28 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (3.2 Å) Cite: U2504 determines the species specificity of the A-site cleft antibiotics: the structures of tiamulin, homoharringtonine, and bruceantin bound to the ribosome. J.Mol.Biol., 389, 2009
6QID	Crystal structure of DEAH-box ATPase Prp43-S387A Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, ... Authors: Hamann, F, Ficner, R, Enders, M. Deposit date: 2019-01-18 Release date: 2019-03-06 Last modified: 2024-01-24 Method: X-RAY DIFFRACTION (2.204 Å) Cite: Structural basis for RNA translocation by DEAH-box ATPases. Nucleic Acids Res., 47, 2019
5D08	Crystal structure of selenomethionine-labeled epoxyqueuosine reductase Descriptor: CHLORIDE ION, COBALAMIN, Epoxyqueuosine reductase, ... Authors: Dowling, D.P, Miles, Z.D, Kohrer, C, Bandarian, V, Drennan, C.L. Deposit date: 2015-08-02 Release date: 2016-09-28 Last modified: 2019-11-20 Method: X-RAY DIFFRACTION (1.747 Å) Cite: Molecular basis of cobalamin-dependent RNA modification. Nucleic Acids Res., 44, 2016
5ZX2	Mycobacterium tuberculosis RNA polymerase transcription initiation complex with ECF sigma factor sigma H and 7nt RNA Descriptor: DNA (47-MER), DNA (48-MER), DNA-directed RNA polymerase subunit alpha, ... Authors: Li, L, Zhang, Y. Deposit date: 2018-05-17 Release date: 2019-03-20 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (2.8 Å) Cite: Structural basis for transcription initiation by bacterial ECF sigma factors. Nat Commun, 10, 2019
2CBN	Crystal structure of ZipD from Escherichia coli Descriptor: RIBONUCLEASE Z, ZINC ION Authors: Pohl, E, Meyer-Klaucke, W, Kostelecky, B. Deposit date: 2006-01-06 Release date: 2006-02-15 Last modified: 2024-05-08 Method: X-RAY DIFFRACTION (2.9 Å) Cite: The Crystal Structure of the Zinc Phosphodiesterase from Escherichia Coli Provides Insight Into Function and Cooperativity of Trnase Z-Family Proteins. J.Bacteriol., 188, 2006
2DKF	Crystal Structure of TTHA0252 from Thermus thermophilus HB8, a RNA Degradation Protein of the Metallo-beta-lactamase Superfamily Descriptor: ZINC ION, metallo-beta-lactamase superfamily protein Authors: Ishikawa, I, Nakagawa, N, Kuramitsu, S, Yokoyama, S, Masui, R, RIKEN Structural Genomics/Proteomics Initiative (RSGI) Deposit date: 2006-04-10 Release date: 2006-12-05 Last modified: 2011-07-13 Method: X-RAY DIFFRACTION (2.8 Å) Cite: Crystal structure of TTHA0252 from Thermus thermophilus HB8, a RNA degradation protein of the metallo-beta-lactamase superfamily J.Biochem.(Tokyo), 140, 2006
6S8R	D. melanogaster RNA helicase Me31B in complex with GIGYF Descriptor: ACETATE ION, ATP-dependent RNA helicase me31b, GIGYF family protein CG11148 Authors: Peter, D, Valkov, E. Deposit date: 2019-07-10 Release date: 2019-09-04 Last modified: 2024-01-24 Method: X-RAY DIFFRACTION (2.41 Å) Cite: Molecular basis for GIGYF-Me31B complex assembly in 4EHP-mediated translational repression. Genes Dev., 33, 2019
6UTY	E. coli sigma-S transcription initiation complex with a mismatching CTP ("Old" crystal soaked with CTP for 30 minutes) Descriptor: CYTIDINE-5'-TRIPHOSPHATE, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... Authors: Zuo, Y, De, S, Steitz, T.A. Deposit date: 2019-10-30 Release date: 2020-08-26 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (4.15 Å) Cite: Structural Insights into Transcription Initiation from De Novo RNA Synthesis to Transitioning into Elongation. Iscience, 23, 2020
6UTX	E. coli sigma-S transcription initiation complex with an empty bubble ("Old" crystal) Descriptor: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... Authors: Zuo, Y, De, S, Steitz, T.A. Deposit date: 2019-10-30 Release date: 2020-08-26 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (4.05 Å) Cite: Structural Insights into Transcription Initiation from De Novo RNA Synthesis to Transitioning into Elongation. Iscience, 23, 2020
6UUB	E. coli sigma-S transcription initiation complex with a mismatching UTP ("Fresh" crystal soaked with UTP for 2 hours) Descriptor: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... Authors: Zuo, Y, De, S, Steitz, T.A. Deposit date: 2019-10-30 Release date: 2020-08-26 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (3.955 Å) Cite: Structural Insights into Transcription Initiation from De Novo RNA Synthesis to Transitioning into Elongation. Iscience, 23, 2020
8RBZ	Structure of Integrator-PP2A-SOSS-CTD post-termination complex Descriptor: DNA-directed RNA polymerase subunit, DSS1, Integrator complex subunit 1, ... Authors: Fianu, I, Ochmann, M, Walshe, J.L, Cramer, P. Deposit date: 2023-12-05 Release date: 2024-02-07 Last modified: 2024-05-15 Method: ELECTRON MICROSCOPY (3.7 Å) Cite: Structural basis of Integrator-dependent RNA polymerase II termination. Nature, 629, 2024
3CCQ	Structure of Anisomycin resistant 50S Ribosomal Subunit: 23S rRNA mutation A2488U Descriptor: 23S RIBOSOMAL RNA, 50S ribosomal protein L10E, 50S ribosomal protein L10e, ... Authors: Blaha, G, Gurel, G. Deposit date: 2008-02-26 Release date: 2008-05-20 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (2.9 Å) Cite: Mutations outside the anisomycin-binding site can make ribosomes drug-resistant. J.Mol.Biol., 379, 2008
7RDQ	Cryo-EM structure of Thermus thermophilus reiterative transcription complex with 11nt oligo-G RNA Descriptor: DNA (31-MER) nontemplate strand, DNA (31-MER) template strand, DNA-directed RNA polymerase subunit alpha, ... Authors: Liu, Y, Ebright, R.H. Deposit date: 2021-07-10 Release date: 2022-02-02 Last modified: 2024-06-05 Method: ELECTRON MICROSCOPY (3 Å) Cite: Structural and mechanistic basis of reiterative transcription initiation. Proc.Natl.Acad.Sci.USA, 119, 2022
6OMF	CryoEM structure of SigmaS-transcription initiation complex with activator Crl Descriptor: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... Authors: Jaramillo Cartagena, A, Darst, S.A, Campbell, E.A. Deposit date: 2019-04-18 Release date: 2019-08-28 Last modified: 2024-03-13 Method: ELECTRON MICROSCOPY (3.26 Å) Cite: Structural basis for transcription activation by Crl through tethering of sigmaSand RNA polymerase. Proc.Natl.Acad.Sci.USA, 116, 2019
4ZDP	The crystal structure of Y334C mutant of human SepSecS in complex with selenocysteine tRNA (tRNASec) Descriptor: (5-HYDROXY-4,6-DIMETHYLPYRIDIN-3-YL)METHYL DIHYDROGEN PHOSPHATE, O-phosphoseryl-tRNA(Sec) selenium transferase, PHOSPHATE ION, ... Authors: French, R.L, Simonovic, M. Deposit date: 2015-04-17 Release date: 2016-04-20 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (2.703 Å) Cite: Structural basis for early-onset neurological disorders caused by mutations in human selenocysteine synthase. Sci Rep, 6, 2016
3CCU	Structure of Anisomycin resistant 50S Ribosomal Subunit: 23S rRNA mutation G2482C Descriptor: 23S RIBOSOMAL RNA, 50S ribosomal protein L10E, 50S ribosomal protein L10e, ... Authors: Blaha, G, Gurel, G. Deposit date: 2008-02-26 Release date: 2008-05-20 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (2.8 Å) Cite: Mutations outside the anisomycin-binding site can make ribosomes drug-resistant. J.Mol.Biol., 379, 2008
3CCL	Structure of Anisomycin resistant 50S Ribosomal Subunit: 23S rRNA mutation U2535C. Density for Anisomycin is visible but not included in model. Descriptor: 23S RIBOSOMAL RNA, 50S ribosomal protein L10E, 50S ribosomal protein L10e, ... Authors: Blaha, G, Gurel, G. Deposit date: 2008-02-26 Release date: 2008-05-20 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (2.9 Å) Cite: Mutations outside the anisomycin-binding site can make ribosomes drug-resistant. J.Mol.Biol., 379, 2008
3CCV	Structure of Anisomycin resistant 50S Ribosomal Subunit: 23S rRNA mutation G2616A Descriptor: 23S RIBOSOMAL RNA, 50S ribosomal protein L10E, 50S ribosomal protein L10e, ... Authors: Blaha, G, Gurel, G. Deposit date: 2008-02-26 Release date: 2008-05-20 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (2.9 Å) Cite: Mutations outside the anisomycin-binding site can make ribosomes drug-resistant. J.Mol.Biol., 379, 2008
3CCE	Structure of Anisomycin resistant 50S Ribosomal Subunit: 23S rRNA mutation U2535A Descriptor: 23S RIBOSOMAL RNA, 50S ribosomal protein L10E, 50S ribosomal protein L10e, ... Authors: Blaha, G, Gurel, G. Deposit date: 2008-02-25 Release date: 2008-05-20 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (2.75 Å) Cite: Mutations outside the anisomycin-binding site can make ribosomes drug-resistant. J.Mol.Biol., 379, 2008
5ZX3	Mycobacterium tuberculosis RNA polymerase holoenzyme with ECF sigma factor sigma H Descriptor: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... Authors: Li, L, Zhang, Y. Deposit date: 2018-05-17 Release date: 2019-03-20 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (2.751 Å) Cite: Structural basis for transcription initiation by bacterial ECF sigma factors. Nat Commun, 10, 2019
4ZDO	The crystal structure of T325S mutant of human SepSecS in complex with selenocysteine tRNA (tRNASec) Descriptor: (5-HYDROXY-4,6-DIMETHYLPYRIDIN-3-YL)METHYL DIHYDROGEN PHOSPHATE, O-phosphoseryl-tRNA(Sec) selenium transferase, PHOSPHATE ION, ... Authors: French, R.L, Simonovic, M. Deposit date: 2015-04-17 Release date: 2016-04-20 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (2.65 Å) Cite: Structural basis for early-onset neurological disorders caused by mutations in human selenocysteine synthase. Sci Rep, 6, 2016
3CCM	Structure of Anisomycin resistant 50S Ribosomal Subunit: 23S rRNA mutation G2611U Descriptor: 23S RIBOSOMAL RNA, 50S ribosomal protein L10E, 50S ribosomal protein L10e, ... Authors: Blaha, G, Gurel, G. Deposit date: 2008-02-26 Release date: 2008-05-20 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (2.55 Å) Cite: Mutations outside the anisomycin-binding site can make ribosomes drug-resistant. J.Mol.Biol., 379, 2008
3CCJ	Structure of Anisomycin resistant 50S Ribosomal Subunit: 23S rRNA mutation C2534U Descriptor: 23S RIBOSOMAL RNA, 50S ribosomal protein L10E, 50S ribosomal protein L10e, ... Authors: Blaha, G, Gurel, G. Deposit date: 2008-02-26 Release date: 2008-05-20 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (3.3 Å) Cite: Mutations outside the anisomycin-binding site can make ribosomes drug-resistant. J.Mol.Biol., 379, 2008
3CCR	Structure of Anisomycin resistant 50S Ribosomal Subunit: 23S rRNA mutation A2488C. Density for anisomycin is visible but not included in the model. Descriptor: 23S RIBOSOMAL RNA, 50S ribosomal protein L10E, 50S ribosomal protein L10e, ... Authors: Blaha, G, Gurel, G. Deposit date: 2008-02-26 Release date: 2008-05-20 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (3 Å) Cite: Mutations outside the anisomycin-binding site can make ribosomes drug-resistant. J.Mol.Biol., 379, 2008
7Y41	Mycobacterium smegmatis 50S ribosomal subunit from Log Phase of growth Descriptor: 23S ribosomal RNA, 50S ribosomal protein L10, 50S ribosomal protein L11, ... Authors: Sengupta, J, Baid, P. Deposit date: 2022-06-13 Release date: 2023-05-03 Last modified: 2024-05-15 Method: ELECTRON MICROSCOPY (4.1 Å) Cite: Cryo-EM captures a unique conformational rearrangement in 23S rRNA helices of the Mycobacterium 50S subunit. Int.J.Biol.Macromol., 253, 2023

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