3CCR

Structure of Anisomycin resistant 50S Ribosomal Subunit: 23S rRNA mutation A2488C. Density for anisomycin is visible but not included in the model.

Summary for 3CCR

• Entry DOI: 10.2210/pdb3ccr/pdb
• Related: 3CC2 3CC4 3CC7 3CCE 3CCJ 3CCL 3CCM 3CCQ 3CCS 3CCU 3CCV 3CD6
• Descriptor: 50S ribosomal protein L2P, 50S ribosomal protein L13P, 50S ribosomal protein L14P, ... (38 entities in total)
• Functional Keywords: a2488c mutation, 23s rrna, large ribosomal subunit, ribosome
• Biological source: Haloarcula marismortui (Halobacterium marismortui); More
• Cellular location: Cytoplasm : P12743
• Total number of polymer chains: 31
• Total formula weight: 1493224.80

Authors

Blaha, G.,Gurel, G. (deposition date: 2008-02-26, release date: 2008-05-20, Last modification date: 2024-02-21)

• Primary citation: Blaha, G.,Gurel, G.,Schroeder, S.J.,Moore, P.B.,Steitz, T.A.; Mutations outside the anisomycin-binding site can make ribosomes drug-resistant.; J.Mol.Biol., 379:505-519, 2008; PubMed: 18455733; DOI: 10.1016/j.jmb.2008.03.075

Experimental method

X-RAY DIFFRACTION (3 Å)