6UUB

E. coli sigma-S transcription initiation complex with a mismatching UTP ("Fresh" crystal soaked with UTP for 2 hours)

This is a non-PDB format compatible entry.

Summary for 6UUB

• Entry DOI: 10.2210/pdb6uub/pdb
• Descriptor: DNA-directed RNA polymerase subunit alpha, URIDINE 5'-TRIPHOSPHATE, DNA-directed RNA polymerase subunit beta, ... (10 entities in total)
• Functional Keywords: transcription initiation, rna polymerase, dna promoter, transcription bubble, de novo rna synthesis, dna scrunching, sigma-s factor, transcription, transferase-dna complex, transferase/dna
• Biological source: Escherichia coli; More
• Total number of polymer chains: 8
• Total formula weight: 440423.10

Authors

Zuo, Y.,De, S.,Steitz, T.A. (deposition date: 2019-10-30, release date: 2020-08-26, Last modification date: 2023-10-11)

• Primary citation: Zuo, Y.,De, S.,Feng, Y.,Steitz, T.A.; Structural Insights into Transcription Initiation from De Novo RNA Synthesis to Transitioning into Elongation.; Iscience, 23:101445-101445, 2020; PubMed: 32829286; DOI: 10.1016/j.isci.2020.101445

Experimental method

X-RAY DIFFRACTION (3.955 Å)