PDB: 960 resultsInfo pagesStatus searchChemie searchBIRD

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7MA0	HIV-1 Protease (I84V) in Complex with LR2-91 Descriptor: (3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-yl {(2S,3R)-3-hydroxy-4-[{[4-(hydroxymethyl)phenyl]sulfonyl}(2-methylpropyl)amino]-1-phenylbutan-2-yl}carbamate, Protease, SULFATE ION Authors: Lockbaum, G.J, Schiffer, C.A. Deposit date: 2021-03-31 Release date: 2022-04-27 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (1.92 Å) Cite: HIV-1 Protease (I84V) in Complex with LR2-91 To Be Published
7MA2	HIV-1 Protease (I84V) in Complex with a Darunavir Derivative Descriptor: (3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-yl [(2S,3R)-4-{[(1,3-benzothiazol-6-yl)sulfonyl](2-methylpropyl)amino}-3-hydroxy-1-phenylbutan-2-yl]carbamate, Protease, SULFATE ION Authors: Lockbaum, G.J, Schiffer, C.A. Deposit date: 2021-03-31 Release date: 2022-04-27 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (1.869 Å) Cite: HIV-1 Protease (I84V) in Complex with a Darunavir Derivative To Be Published
7M9Z	HIV-1 Protease (I84V) in Complex with TMC-126 Descriptor: (3R,3AS,6AR)-HEXAHYDROFURO[2,3-B]FURAN-3-YL [(1S,2R)-1-BENZYL-2-HYDROXY-3-{ISOBUTYL[(4-METHOXYPHENYL)SULFONYL]AMINO}PROPYL]CARBAMATE, Protease, SULFATE ION Authors: Lockbaum, G.J, Schiffer, C.A. Deposit date: 2021-03-31 Release date: 2022-04-27 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (1.828 Å) Cite: HIV-1 Protease (I84V) in Complex with TMC-126 To Be Published
7MAH	HIV-1 Protease (I84V) in Complex with PU4 (LR2-78) Descriptor: Protease, SULFATE ION, diethyl [(4-{(2S,3R)-4-{[(2H-1,3-benzodioxol-5-yl)sulfonyl][(2S)-2-methylbutyl]amino}-2-[({[(3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-yl]oxy}carbonyl)amino]-3-hydroxybutyl}phenoxy)methyl]phosphonate Authors: Lockbaum, G.J, Schiffer, C.A. Deposit date: 2021-03-31 Release date: 2022-04-27 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (1.881 Å) Cite: HIV-1 Protease (I84V) in Complex with PU4 (LR2-78) To Be Published
7MAB	HIV-1 Protease (I84V) in Complex with GS-8374 Descriptor: DIETHYL ({4-[(2S,3R)-2-({[(3R,3AS,6AR)-HEXAHYDROFURO[2,3-B]FURAN-3-YLOXY]CARBONYL}AMINO)-3-HYDROXY-4-{ISOBUTYL[(4-METHOXYPHENYL)SULFONYL]AMINO}BUTYL]PHENOXY}METHYL)PHOSPHONATE, Protease, SULFATE ION Authors: Lockbaum, G.J, Schiffer, C.A. Deposit date: 2021-03-31 Release date: 2022-04-27 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (1.879 Å) Cite: HIV-1 Protease (I84V) in Complex with GS-8374 To Be Published
7N6T	Crystal structure of inhibitor-free HIV-1 PRS17 revertant mutant PRS17 V48G Descriptor: Protease Authors: Burnaman, S.H, Wang, Y.-F, Weber, I.T. Deposit date: 2021-06-09 Release date: 2021-09-08 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (1.32 Å) Cite: Revertant mutation V48G alters conformational dynamics of highly drug resistant HIV protease PRS17. J.Mol.Graph.Model., 108, 2021
7N6V	Crystal structure of HIV-1 Protease multiple mutants PRS17 with Revertant mutation V48G bound to inhibitor Amprenavir Descriptor: GLYCEROL, Protease, {3-[(4-AMINO-BENZENESULFONYL)-ISOBUTYL-AMINO]-1-BENZYL-2-HYDROXY-PROPYL}-CARBAMIC ACID TETRAHYDRO-FURAN-3-YL ESTER Authors: Burnaman, S.H, Wang, Y.-F, Weber, I.T. Deposit date: 2021-06-09 Release date: 2021-09-08 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (1.39 Å) Cite: Revertant mutation V48G alters conformational dynamics of highly drug resistant HIV protease PRS17. J.Mol.Graph.Model., 108, 2021
7N6X	Crystal structure of HIV-1 Protease multiple mutants PRS17 bound to inhibitor Amprenavir Descriptor: Protease, {3-[(4-AMINO-BENZENESULFONYL)-ISOBUTYL-AMINO]-1-BENZYL-2-HYDROXY-PROPYL}-CARBAMIC ACID TETRAHYDRO-FURAN-3-YL ESTER Authors: Burnaman, S.H, Wang, Y.-F, Weber, I.T. Deposit date: 2021-06-09 Release date: 2021-09-08 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (1.47 Å) Cite: Revertant mutation V48G alters conformational dynamics of highly drug resistant HIV protease PRS17. J.Mol.Graph.Model., 108, 2021
7SEP	Cryo-EM Structure of the RT component of the HIV-1 Pol Polyprotein Descriptor: Gag-Pol polyprotein Authors: Lyumkis, D, Passos, D, Arnold, E, Harrison, J.J.E. Deposit date: 2021-10-01 Release date: 2022-07-27 Last modified: 2024-06-05 Method: ELECTRON MICROSCOPY (3.8 Å) Cite: Cryo-EM structure of the HIV-1 Pol polyprotein provides insights into virion maturation. Sci Adv, 8, 2022
7SJX	Cryo-EM Structure of the PR-RT components of the HIV-1 Pol Polyprotein Descriptor: Gag-Pol polyprotein Authors: Lyumkis, D, Passos, D, Arnold, E, Harrison, J.J.E.K, Ruiz, F.X. Deposit date: 2021-10-19 Release date: 2022-07-27 Last modified: 2023-08-16 Method: ELECTRON MICROSCOPY (8.2 Å) Cite: Cryo-EM structure of the HIV-1 Pol polyprotein provides insights into virion maturation. Sci Adv, 8, 2022

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